Training in the Genetics of Human Disease
The TL1 program provides training to post-doctoral fellows in the genetics of human disease, creating future leaders in genome analysis and interpretation. The program builds on the University of Utah’s strengths in sequencing technology and analysis, the Utah Population Database, and the Utah Genome Project. In addition, trainees benefit from existing and expanding bridges between basic and clinical departments at the University of Utah.
Trainees are co-mentored by clinical faculty members who have expertise in specific diseases and by faculty on the steering committee of the Utah Genome Project. TL1 scholars receive training in multiple areas, including:
- Informatics and study design using the UPDB,
- Analysis of whole genome sequencing data,
- The use of analytic software such as the Variant Annotation, Analysis and Search Tool (VAAST).
TL1s also benefit from cross training in clinical and translational research competencies using the education framework for the master's in clinical investigation (MSCI) program. Trainees with an MD or other clinical backgrounds are given formal scientific training in genetics, molecular biology, and computational analysis, and PhD trainees are embedded in the clinical enterprise. Upon completion of the program, trainees are conversant in both the clinical and basic science arenas.