Lorise C. Gahring, PhD

Languages

  • English

Academic Information

  • Departments: Dentistry - Adjunct Professor, Internal Medicine - Professor, Pathology - Adjunct Professor
  • Divisions: Geriatrics, Microbiology and Immunology

Academic Office Information

  • 801-585-6338
  • School of Medicine
    Division of Geriatrics
    30 N 1900 E, Room: AB193
    Salt Lake City, UT 84132

Email: Lorise.Gahring@hsc.utah.edu

Academic Bio

Dr. Gahring joined the faculty team of the Division of Geriatrics in 1993 and also holds an adjunct professorship in the Pathology Department, specializing in microbiology and immunology.She is interested in how inflammation affects diseases such as Alzheimer's, Parkinson's, Multiple Sclerosis, Epilepsy or just normal aging. Her lab studies several aspects of neuroinflammation that involve how inflammatory cytokines interact with neurotransmitter receptors. During the course of a peripheral inflammatory event, cytokines are produced locally and upon release into the blood stream stimulate cells within the central nervous system (CNS) to produce more cytokines.In most cases, inflammatory cytokines are produced transiently in the brain and have a positive effect on neuronal survival. Interleukin-1 ( a and b ), interleukin-6 (IL-6), and tumor necrosis factor alpha (TNF a ) can protect neurons against subsequent toxic challenges (including b -amyloid peptide, paraquat, and N-methyl-d-aspartic acid (NMDA)). Chronic stimulation of these inflammatory cytokines, however, can have deleterious effects on neuronal viability. Overexpression of inflammatory cytokines such as TNF is detected in neurological diseases. Dr. Gahring's laboratory investigates the effects of inflammatory cytokines on neurons through measuring intracellular events induced by these proteins. We require proper immune and inflammatory responses to maintain a healthy status during microbial assault, but with age these same processes become dysregulated and can themselves contribute to the pathogenesis of many age-related diseases. In particular, the tight control of signaling among key mediators of the immune and inflammatory system, the inflammatory cytokines, become compromised. Dr. Gahring's lab studies several aspects of inflammation that involve alterations in inflammatory cytokine production and how these alterations impact on nicotinic receptors, which have anti-inflammatory properties. In the mouse model, we can determine the interplay between the cytokines and the nicotinic receptors to assess how maintenance of the balance between these systems can prevent several pathologies of the aged.

Education History

Type School Degree
Postdoctoral Fellowship Research Institute of Scripps Clinic
Immunology
Postdoctoral Fellow
Postdoctoral Fellowship Research Institute of Scripps Clinic
Molecular Biology
Postdoctoral Fellow
Doctoral Training University of Utah
Pathology, Cell Biology & Immunology
Ph.D.
Graduate Training California State University Fullerton
Biology, Immunology
M.A.
Undergraduate University of California
Biology
B.S.

Selected Publications

Journal Article

  1. The nicotinic receptor Alpha7 impacts the mouse lung response to LPS through multiple mechanisms.Enioutina EY, Myers EJ, Tvrdik P, Hoidal JR, Rogers SW, Gahring LC (2015). The nicotinic receptor Alpha7 impacts the mouse lung response to LPS through multiple mechanisms. PLoS One, 10(3), e0121128.
  2. Age-related onset of obesity corresponds with metabolic dysregulation and altered microglia morphology in mice deficient for Ifitm proteins.Wee YS, Weis JJ, Gahring LC, Rogers SW, Weis JH (2015). Age-related onset of obesity corresponds with metabolic dysregulation and altered microglia morphology in mice deficient for Ifitm proteins. PLoS One, 10(4), e0123218.
  3. Upregulation of Nicotinic Acetylcholine Receptor alph4+beta2 through a Ligand-Independent PI3Kbeta Mechanism That Is Enhanced by TNFalpha and the Jak2/p38Mapk Pathways.Rogers SW, Gahring LC (2015). Upregulation of Nicotinic Acetylcholine Receptor alph4+beta2 through a Ligand-Independent PI3Kbeta Mechanism That Is Enhanced by TNFalpha and the Jak2/p38Mapk Pathways. PLoS One, 10(11), e0143319.
  4. Nicotinic receptor Alpha7 expression during mouse adrenal gland development.Gahring LC, Myers E, Palumbos S, Rogers SW (2014). Nicotinic receptor Alpha7 expression during mouse adrenal gland development. PLoS One, 9(8), e103861.
  5. Nicotinic receptor alpha7 expression identifies a novel hematopoietic progenitor lineage.Gahring LC, Enioutina EY, Myers EJ, Spangrude GJ, Efimova OV, Kelley TW, Tvrdik P, Capecchi MR, Rogers SW (2013). Nicotinic receptor alpha7 expression identifies a novel hematopoietic progenitor lineage. PLoS One, 8(3), e57481.
  6. The expression of nicotinic receptor alpha7 during cochlear development.Rogers SW, Myers EJ, Gahring LC (2012). The expression of nicotinic receptor alpha7 during cochlear development. Brain Behav, 2(5), 628-39.
  7. Prenatal ablation of nicotinic receptor alpha7 cell lineages produces lumbosacral spina bifida the severity of which is modified by choline and nicotine exposure.Rogers SW, Tvrdik P, Capecchi MR, Gahring LC (2012). Prenatal ablation of nicotinic receptor alpha7 cell lineages produces lumbosacral spina bifida the severity of which is modified by choline and nicotine exposure. Am J Med Genet A, 158A(5), 1135-44.
  8. Nicotinic receptor Alpha7 expression during tooth morphogenesis reveals functional pleiotropy.Rogers SW, Gahring LC (2012). Nicotinic receptor Alpha7 expression during tooth morphogenesis reveals functional pleiotropy. PLoS One, 7(5), e36467.
  9. Choline promotes nicotinic receptor alpha4 + beta2 up-regulation.Gahring LC, Vasquez-Opazo GA, Rogers SW (2010). Choline promotes nicotinic receptor alpha4 + beta2 up-regulation. J Biol Chem, 285(26), 19793-801.
  10. Nicotinic receptor subunit alpha5 modifies assembly, up-regulation, and response to pro-inflammatory cytokines.Gahring LC, Rogers SW (2010). Nicotinic receptor subunit alpha5 modifies assembly, up-regulation, and response to pro-inflammatory cytokines. J Biol Chem, 285(34), 26049-57.
  11. Neuronal nicotinic alpha7 receptors modulate early neutrophil infiltration to sites of skin inflammation.Gahring LC, Osborne AV, Reed M, Rogers SW (2010). Neuronal nicotinic alpha7 receptors modulate early neutrophil infiltration to sites of skin inflammation. Journal of Neuroinflammation, 7(1), 38.
  12. Tumor necrosis factor alpha enhances nicotinic receptor up-regulation via a p38MAPK-dependent pathway.Gahring LC, Osborne-Hereford AV, Vasquez-Opazo GA, Rogers SW (2008). Tumor necrosis factor alpha enhances nicotinic receptor up-regulation via a p38MAPK-dependent pathway. J Biol Chem, 283(2), 693-9.
  13. Neuronal nicotinic alpha7 receptors modulate inflammatory cytokine production in the skin following ultraviolet radiation.Osborne-Hereford AV, Rogers SW, Gahring LC (2008). Neuronal nicotinic alpha7 receptors modulate inflammatory cytokine production in the skin following ultraviolet radiation. J Neuroimmunol, 193(1-2), 130-9.
  14. Nicotinic acetylcholine receptor expression in the hippocampus of 27 mouse strains reveals novel inhibitory circuitry.Gahring LC, Rogers SW (2008). Nicotinic acetylcholine receptor expression in the hippocampus of 27 mouse strains reveals novel inhibitory circuitry. Hippocampus, 18(8), 737-49.
  15. Mouse chromosome 11 harbors genetic determinants of hippocampal strain-specific nicotinic receptor expression.Rogers SW, Weis JJ, Ma Y, Teuscher C, Gahring LC (2008). Mouse chromosome 11 harbors genetic determinants of hippocampal strain-specific nicotinic receptor expression. Hippocampus, 18(8), 750-7.
  16. A candidate gene approach identifies the CHRNA5-A3-B4 region as a risk factor for age-dependent nicotine addiction.Weiss RB, Baker TB, Cannon DS, von Niederhausern A, Dunn DM, Matsunami N, Singh NA, Baird L, Coon H, McMahon WM, Piper ME, Fiore MC, Scholand MB, Connett JE, Kanner RE, Gahring LC, Rogers SW, Hoidal JR, Leppert MF (2008). A candidate gene approach identifies the CHRNA5-A3-B4 region as a risk factor for age-dependent nicotine addiction. PLoS Genet, 4(7), e1000125.
  17. Mouse strain-specific changes in nicotinic receptor expression with age.Gahring LC, Persiyanov K, Rogers SW (2005). Mouse strain-specific changes in nicotinic receptor expression with age. Neurobiol Aging, 26(6), 973-80.
  18. Pro-inflammatory cytokines modify neuronal nicotinic acetylcholine receptor assembly.Gahring LC, Days EL, Kaasch T, Gonzalez de Mendoza M, Owen L, Persiyanov K, Rogers SW (2005). Pro-inflammatory cytokines modify neuronal nicotinic acetylcholine receptor assembly. J Neuroimmunol, 166(1-2), 88-101.
  19. Neuronal and astrocyte expression of nicotinic receptor subunit beta4 in the adult mouse brain.Gahring LC, Persiyanov K, Rogers SW (2004). Neuronal and astrocyte expression of nicotinic receptor subunit beta4 in the adult mouse brain. J Comp Neurol, 468(3), 322-33.
  20. Mouse strain-specific nicotinic acetylcholine receptor expression by inhibitory interneurons and astrocytes in the dorsal hippocampus.Gahring LC, Persiyanov K, Dunn D, Weiss R, Meyer EL, Rogers SW (2004). Mouse strain-specific nicotinic acetylcholine receptor expression by inhibitory interneurons and astrocytes in the dorsal hippocampus. J Comp Neurol, 468(3), 334-46.
  21. Age-related loss of neuronal nicotinic receptor expression in the aging mouse hippocampus corresponds with cyclooxygenase-2 and PPARgamma expression and is altered by long-term NS398 administration.Gahring LC, Persiyanov K, Days EL, Rogers SW (2004). Age-related loss of neuronal nicotinic receptor expression in the aging mouse hippocampus corresponds with cyclooxygenase-2 and PPARgamma expression and is altered by long-term NS398 administration. J Neurobiol, 62(4), 453-468.
  22. Glutamate receptor subunit 3 is modified by site-specific limited proteolysis including cleavage by gamma-secretase.Meyer EL, Strutz N, Gahring LC, Rogers SW (2003). Glutamate receptor subunit 3 is modified by site-specific limited proteolysis including cleavage by gamma-secretase. J Biol Chem, 278(26), 23786-96.
  23. Nicotine-induced neuroprotection against N-methyl-D-aspartic acid or beta-amyloid peptide occur through independent mechanisms distinguished by pro-inflammatory cytokines.Gahring LC, Meyer EL, Rogers SW (2003). Nicotine-induced neuroprotection against N-methyl-D-aspartic acid or beta-amyloid peptide occur through independent mechanisms distinguished by pro-inflammatory cytokines. J Neurochem, 87(5), 1125-36.
  24. Nicotine preconditioning antagonizes activity-dependent caspase proteolysis of a glutamate receptor.Meyer EL, Gahring LC, Rogers SW (2002). Nicotine preconditioning antagonizes activity-dependent caspase proteolysis of a glutamate receptor. J Biol Chem, 277(13), 10869-75.
  25. Immunolocalization of iron regulatory protein expression in the murine central nervous system.Leibold EA, Gahring LC, Rogers SW (2001). Immunolocalization of iron regulatory protein expression in the murine central nervous system. Histochem Cell Biol, 115(3), 195-203.
  26. Neuronal nicotinic acetylcholine receptor expression by O2A/oligodendrocyte progenitor cells.Rogers SW, Gregori NZ, Carlson N, Gahring LC, Noble M (2001). Neuronal nicotinic acetylcholine receptor expression by O2A/oligodendrocyte progenitor cells. Glia, 33(4), 306-13.
  27. Identification of the amino acids on a neuronal glutamate receptor recognized by an autoantibody from a patient with paraneoplastic syndrome.Carlson NG, Gahring LC, Rogers SW (2001). Identification of the amino acids on a neuronal glutamate receptor recognized by an autoantibody from a patient with paraneoplastic syndrome. J Neurosci Res, 63(6), 480-5.
  28. Granzyme B proteolysis of a neuronal glutamate receptor generates an autoantigen and is modulated by glycosylation.Gahring L, Carlson NG, Meyer EL, Rogers SW (2001). Granzyme B proteolysis of a neuronal glutamate receptor generates an autoantigen and is modulated by glycosylation. J Immunol, 166(3), 1433-8.
  29. RNA editing (Q/R site) and flop/flip splicing of AMPA receptor transcripts in young and old brains.Carlson NG, Howard J, Gahring LC, Rogers SW (2000). RNA editing (Q/R site) and flop/flip splicing of AMPA receptor transcripts in young and old brains. Neurobiol Aging, 21(4), 599-606.
  30. Alcohol blocks TNFalpha but not other cytokine-mediated neuroprotection to NMDA.Gahring LC, Carlson NG, Wieggel WA, Howard J, Rogers SW (1999). Alcohol blocks TNFalpha but not other cytokine-mediated neuroprotection to NMDA. Alcohol Clin Exp Res, 23(10), 1571-9.
  31. A model for a glutamate receptor agonist antibody-binding site.McDonald S, Carlson NG, Gahring LC, Ely KR, Rogers SW (1999). A model for a glutamate receptor agonist antibody-binding site. J Mol Recognit, 12(4), 219-25.
  32. Inflammatory cytokines IL-1 alpha, IL-1 beta, IL-6, and TNF-alpha impart neuroprotection to an excitotoxin through distinct pathways.Carlson NG, Wieggel WA, Chen J, Bacchi A, Rogers SW, Gahring LC (1999). Inflammatory cytokines IL-1 alpha, IL-1 beta, IL-6, and TNF-alpha impart neuroprotection to an excitotoxin through distinct pathways. J Immunol, 163(7), 3963-8.
  33. Glutamate receptor GluR1 expression is altered selectively by chronic audiogenic seizures in the Frings mouse brain.Rogers SW, Gahring LC, White HS (1998). Glutamate receptor GluR1 expression is altered selectively by chronic audiogenic seizures in the Frings mouse brain. J Neurobiol, 35(2), 209-16.
  34. Nicotine blocks TNF-alpha-mediated neuroprotection to NMDA by an alpha-bungarotoxin-sensitive pathway.Carlson NG, Bacchi A, Rogers SW, Gahring LC (1998). Nicotine blocks TNF-alpha-mediated neuroprotection to NMDA by an alpha-bungarotoxin-sensitive pathway. J Neurobiol, 35(1), 29-36.
  35. Antibodies prepared to neuronal glutamate receptor subunit3 bind IFNalpha-receptors: implications for an autoimmune process.Gahring LC, Carlson NG, Rogers SW (1998). Antibodies prepared to neuronal glutamate receptor subunit3 bind IFNalpha-receptors: implications for an autoimmune process. Autoimmunity, 28(4), 243-8.
  36. Age-related changes in neuronal nicotinic acetylcholine receptor subunit alpha4 expression are modified by long-term nicotine administration.Rogers SW, Gahring LC, Collins AC, Marks M (1998). Age-related changes in neuronal nicotinic acetylcholine receptor subunit alpha4 expression are modified by long-term nicotine administration. J Neurosci, 18(13), 4825-32.
  37. Interleukin-1alpha in the brain is induced by audiogenic seizure.Gahring LC, White HS, Skradski SL, Carlson NG, Rogers SW (1997). Interleukin-1alpha in the brain is induced by audiogenic seizure. Neurobiol Dis, 3(4), 263-9.
  38. Identification of amino acids in the glutamate receptor, GluR3, important for antibody-binding and receptor-specific activation.Carlson NG, Gahring LC, Twyman RE, Rogers SW (1997). Identification of amino acids in the glutamate receptor, GluR3, important for antibody-binding and receptor-specific activation. J Biol Chem, 272(17), 11295-301.
  39. Autoantibodies to glutamate receptor subunit GluR2 in nonfamilial olivopontocerebellar degeneration.Gahring LC, Rogers SW, Twyman RE (1997). Autoantibodies to glutamate receptor subunit GluR2 in nonfamilial olivopontocerebellar degeneration. Neurology, 48(2), 494-500.
  40. Neuronal expression of tumor necrosis factor alpha in the murine brain.Gahring LC, Carlson NG, Kulmar RA, Rogers SW (1996). Neuronal expression of tumor necrosis factor alpha in the murine brain. Neuroimmunomodulation, 3(5), 289-303.
  41. Kainic acid induced excitotoxicity and cfos expression in fibroblasts transfected with glutamate receptor subunit, GluR1.Gahring LC, Cauley K, Rogers SW (1996). Kainic acid induced excitotoxicity and cfos expression in fibroblasts transfected with glutamate receptor subunit, GluR1. J Neurobiol, 31(1), 56-66.
  42. Nicotinic receptor subunits alpha 3, alpha 4, and beta 2 and high affinity nicotine binding sites are expressed by P19 embryonal cells.Cauley K, Marks M, Gahring LC, Rogers SW (1996). Nicotinic receptor subunits alpha 3, alpha 4, and beta 2 and high affinity nicotine binding sites are expressed by P19 embryonal cells. J Neurobiol, 30(2), 303-14.
  43. Autoantibodies to neuronal glutamate receptors in patients with paraneoplastic neurodegenerative syndrome enhance receptor activation.Gahring LC, Twyman RE, Greenlee JE, Rogers SW (1995). Autoantibodies to neuronal glutamate receptors in patients with paraneoplastic neurodegenerative syndrome enhance receptor activation. Mol Med, 1(3), 245-53.
  44. Glutamate receptor antibodies activate a subset of receptors and reveal an agonist binding site.Twyman RE, Gahring LC, Spiess J, Rogers SW (1995). Glutamate receptor antibodies activate a subset of receptors and reveal an agonist binding site. Neuron, 14(4), 755-62.
  45. Autoantibodies to glutamate receptor GluR3 in Rasmussen's encephalitis.Rogers SW, Andrews PI, Gahring LC, Whisenand T, Cauley K, Crain B, Hughes TE, Heinemann SF, McNamara JO (1994). Autoantibodies to glutamate receptor GluR3 in Rasmussen's encephalitis. Science, 265(5172), 648-51.
  46. The expression of CD45RB on antigen-responsive CD4+ lymphocytes: mouse strain polymorphism and different responses to distinct antigens.Gahring LC, Ernst DN, Romball CG, Thoman ML, Torbett BE, Hobbs M, Weigle WO (1993). The expression of CD45RB on antigen-responsive CD4+ lymphocytes: mouse strain polymorphism and different responses to distinct antigens. Cell Immunol, 148(2), 269-82.
  47. Identification of cultured cells expressing ligand-gated cationic channels.Rogers SW, Gahring LC, Papke RL, Heinemann S (1991). Identification of cultured cells expressing ligand-gated cationic channels. Protein Expr Purif, 2(2-3), 108-16.
  48. Invasion and replication of Salmonella typhimurium in animal cells.Gahring LC, Heffron F, Finlay BB, Falkow S (1990). Invasion and replication of Salmonella typhimurium in animal cells. Infect Immun, 58(2), 443-8.
  49. The effect of aging on the induction of humoral and cellular immunity and tolerance in two long-lived mouse strains.Gahring LC, Weigle WO (1990). The effect of aging on the induction of humoral and cellular immunity and tolerance in two long-lived mouse strains. Cell Immunol, 128(1), 142-51.
  50. The regulatory effects of cytokines on the induction of a peripheral immunologic tolerance in mice.Gahring LC, Weigle WO (1990). The regulatory effects of cytokines on the induction of a peripheral immunologic tolerance in mice. J Immunol, 145(5), 1318-23.
  51. The effect of lipopolysaccharide desensitization on the regulation of in vivo induction of immunologic tolerance and antibody production and in vitro release of IL-1.Weigle WO, Gahring LC, Romball CG, Goodman MG (1989). The effect of lipopolysaccharide desensitization on the regulation of in vivo induction of immunologic tolerance and antibody production and in vitro release of IL-1. J Immunol, 142(4), 1107-13.
  52. The induction of peripheral T cell unresponsiveness in adult mice by monomeric human gamma-globulin.Gahring LC, Weigle WO (1989). The induction of peripheral T cell unresponsiveness in adult mice by monomeric human gamma-globulin. J Immunol, 143(7), 2094-100.
  53. In vivo administration of interleukin 1 to normal mice depresses their capacity to elicit contact hypersensitivity responses: prostaglandins are involved in this modification of immune function.Robertson B, Gahring L, Newton R, Daynes R (1987). In vivo administration of interleukin 1 to normal mice depresses their capacity to elicit contact hypersensitivity responses: prostaglandins are involved in this modification of immune function. J Invest Dermatol, 88(4), 380-7.
  54. Clonal origin of tumors induced by ultraviolet radiation.Burnham DK, Gahring LC, Daynes RA (1986). Clonal origin of tumors induced by ultraviolet radiation. J Natl Cancer Inst, 76(1), 151-8.
  55. Neuropeptide regulation of interleukin-1 activities. Capacity of alpha-melanocyte stimulating hormone to inhibit interleukin-1-inducible responses in vivo and in vitro exhibits target cell selectivity.Robertson BA, Gahring LC, Daynes RA (1986). Neuropeptide regulation of interleukin-1 activities. Capacity of alpha-melanocyte stimulating hormone to inhibit interleukin-1-inducible responses in vivo and in vitro exhibits target cell selectivity. Inflammation, 10(4), 371-85.
  56. Desensitization of animals to the inflammatory effects of ultraviolet radiation is mediated through mechanisms which are distinct from those responsible for endotoxin tolerance.Gahring LC, Daynes RA (1986). Desensitization of animals to the inflammatory effects of ultraviolet radiation is mediated through mechanisms which are distinct from those responsible for endotoxin tolerance. J Immunol, 136(8), 2868-74.
  57. Presence of epidermal-derived thymocyte activating factor/interleukin 1 in normal human stratum corneum.Gahring LC, Buckley A, Daynes RA (1985). Presence of epidermal-derived thymocyte activating factor/interleukin 1 in normal human stratum corneum. J Clin Invest, 76(4), 1585-91.
  58. Effect of ultraviolet radiation on production of epidermal cell thymocyte-activating factor/interleukin 1 in vivo and in vitro.Gahring L, Baltz M, Pepys MB, Daynes R (1984). Effect of ultraviolet radiation on production of epidermal cell thymocyte-activating factor/interleukin 1 in vivo and in vitro. Proc Natl Acad Sci U S A, 81(4), 1198-202.
  59. Tumors arising from injection of cultured murine placental cells into normal animals: direct evidence for placental origin of tumors of two histologic types.Beeson JH, Daynes RA, Weinert AM Jr, Gahring LC (1984). Tumors arising from injection of cultured murine placental cells into normal animals: direct evidence for placental origin of tumors of two histologic types. J Natl Cancer Inst, 73(3), 705-9.
  60. Enhanced tumorigenicity of cloned UV-regressor tumor lines following selected in vivo and in vitro manipulations.Schmitt MK, Roberts LK, Gahring LC, Daynes RA (1983). Enhanced tumorigenicity of cloned UV-regressor tumor lines following selected in vivo and in vitro manipulations. Am J Pathol, 113(3), 269-78.

Review

  1. Neuronal nicotinic acetylcholine receptor expression and function on nonneuronal cells.Gahring LC, Rogers SW (2005). Neuronal nicotinic acetylcholine receptor expression and function on nonneuronal cells. [Review]. AAPS J, 7(4), E885-94.
  2. Gahring LC, Carlson NG, Meyer EL, Days EL, Rogers SW (2003). Neurodegenerative disease and the neuroimmunology of glutamate receptors. [Review]. Adv Cell Mol Bio, 32, 139-158.
  3. Autoimmunity to glutamate receptors in the central nervous system.Gahring LC, Rogers SW (2002). Autoimmunity to glutamate receptors in the central nervous system. [Review]. Crit Rev Immunol, 22(4), 295-316.
  4. Gahring LC, Rogers SW (2002). Autoimmunity to CNS Neurotransmitter Receptors. [Review]. Critical Reviews in Immunology, 22, 295-316.
  5. Antibodies to glutamate receptors: a role in excitatory dysregulation of the central nervous system?Twyman RE, Rogers SW, Gahring LC, Carlson NG, Donevan SD (1999). Antibodies to glutamate receptors: a role in excitatory dysregulation of the central nervous system? [Review]. Adv Neurol, 79, 535-41.
  6. Twyman RE, Rogers SW, Gahring LC, Carlson NG, Donevan SD (1999). Antibodies to glutamate receptors: a role in excitatory dysregulation of the central nervous system? [Review]. Advances in Neurology, 79, 535-541.
  7. Gahring LC, Rogers SW (1998). Autoimmunity to glutamate receptors in Rasmussen's encephalitis: A rare finding or the tip of an iceberg? [Review]. Neuroscientist, 4, 373-379.
  8. The role of autoimmunity to glutamate receptors in neurological disease.Rogers SW, Twyman RE, Gahring LC (1996). The role of autoimmunity to glutamate receptors in neurological disease. [Review]. Mol Med Today, 2(2), 76-81.
  9. Immunobiological consequences of acute and chronic UV exposure.Daynes RA, Samlowski WE, Burnham DK, Gahring LC, Roberts LK (1986). Immunobiological consequences of acute and chronic UV exposure. [Review]. Curr Probl Dermatol, 15, 176-94.
  10. Gahring LC, Daynes RA (1985). The presence of functionally active ETAF/IL-1 in normal human stratum corneum. [Review]. Prog Leuk Biol, 2, 375.
  11. Daynes RA, Sholly SP, Gahring LC, Spangrude GJ (1984). The skin: the primary immunologic organ involved in burn injury. [Review]. J Trauma, 24, 584.

Book Chapter

  1. Gahring LC, Weigle WO (1990). Experimental models of T cell tolerance. In Farid NR, Bona CA (Eds.), Molecular Aspects of Autoimmunity (p. 175). Academic Press, Inc.
  2. Fields PA, Gahring LC, Heffron F, Smith LD (1989). Identification of new avirulent Salmonella strains as potential vaccine delivery systems. In Contemporary Issues in Infectious Diseases (8, p. 221).
  3. Heffron F, Gahring LC, Fields PA, Roth J (1988). Pathogenesis of the intracellular pathogen Salmonella typhimurium. In Horowitz M (Ed.), Bacteria-Host Cell Interaction (64, p. 303). UCLA Symposia on Molecular and Cellular Biology.
  4. Daynes RA, Samlowski WE, Burnham DK, Gahring LC, Roberts LK (1986). Biologic consequences of acute and chronic UV exposure. In Therapeutic Photomedicine. S. Karger Press.

Abstract

  1. Gahring, LC, Osborne, AV, Reed, M, Rogers, SW (2010). Neuronal Nicotinic Alpha7 Receptors Modulate Early Neutrophils Infiltration to Sites of Skin Inflammation [Abstract]. J. Neuroinflammation, 7(1), 38.
  2. Gahring, LC, Rogers, SW (2010). The Nicotinic Receptor Subunit Alpha5 Modifies Assembly, Upregulation and Response to Pro-Inflammatory Cytokines [Abstract]. J. Bol. Chem, 285(34), 26049-57.
  3. Gahring, LC, Vasquez-Opazo, G, Rogers, SW (2005). Choline Promotes NicotinicReceptor Alpha4 + Beta2 upregulation [Abstract]. J. Biol. Chem, 19793-801.
  4. Gahring, LC, Osborne-Hereford, AV, Vasquez-Opazo, GA, Rogers, SW (2005). TNFa Enhances Nicotinic Receptor Upregulation Via a p38MAPK-Dependent Pathway [Abstract]. Chemistry: A European Journal, (283), 693-9.
  5. Cauley, K, Marks, M, Gahring, LC, Rogers, SW (2005). Neuronal Nicotinic Receptor Genes a4 and b2 and high affinity nicotine binding sites are induced in P19 Embryonal Carcinoma Cells by Retinoic Acid [Abstract]. Journal of Neurobiology, 30, 303-314.
  6. Gahring, LC, Heffron, F, Finlay, BB, Falkow, S (2005). Normal Replication of Macrophage-sensitive mutants of S. Typhimurium in Epithelial cells [Abstract]. Infection and Immunity, 58, 443-448.

Other

  1. Gahring LC (1995). Paying Attention to a Sick Rabbit. R & D Innovator (2, pp. 6-7).

Patent

  1. Rogers SW, Gahring LC, Twyman RE (2000). Autoantibodies to neurotransmitter receptors. U.S. Patent No. 6,010,854. Washington, D.C.:U.S. Patent and Trademark Office.
  2. Rogers SW, Gahring LC, Twyman RE (1998). Peptide for Blocking Autoantibody-Evoked Activation of Glutamate Receptor Type 3 (GluR3). U.S. Patent No. 5,731,410. Washington, D.C.:U.S. Patent and Trademark Office.