Hong Hua Mu, MD, PhD

Research Interests

  • Cytokines
  • Pertussis Toxin
  • Adjuvants, Immunologic
  • T-Lymphocytes
  • Macrophages
  • Mycoplasma arthritidis
  • Mitogens
  • Superantigens
  • Autoimmune Diseases
  • Immunosenescence
  • Immune-Mediated Diseases

Languages

  • English

Academic Information

  • Departments: Internal Medicine - Research Associate Professor
  • Divisions: Rheumatology

Academic Office Information

  • 801-581-8845
  • School of Medicine
    30 N 1900 E, Room: 4B468
    Salt Lake City, UT 84132

Research Statement

Dr. Mu has been studying how microbial agents can cause host immune-mediated diseases such as autoimmune diseases and immunodeficiency since 1986. Currently his research projects focus on the interplay of innate and adaptive immune system, role of T cell activation and differentiation in the animal models of inflammatory/autoimmune arthritis, septic shock and autoimmune diabetes. By using gene-manipulated mice, Dr. Mu has particularly studied how a variety of immune molecules including TLRs, co-stimulatory molecules, cytokines and chemokines are regulated by a unique mycoplasma superantigen (SAg) MAM, and its host Mycoplasma arthritidis which is known to cause acute to chronic arthritis and lethal toxicity in natural infections of rodents. Over the past 18 years, Dr. Mu ‘s research has been supported by the RO1 grants from NIH and a grant from the Nora Eccles Treadwell Foundation.

Education History

Type School Degree
Fellowship ARUP Reference Laboratory, Department of Diagnostic Immunology (Clinical Diagnostic Immunology)
Visiting Fellow
Postdoctoral Fellowship University of Utah School of Medicine, Department of Pathology
Pathology
Postdoctoral Fellow
Doctoral Training The University of New South Wales
Immunology & Molecular Biology
Ph.D.
Fellowship Shanghai Institute for Pediatric Research, Shanghai Second Medical University
Medicine
Fellow
Graduate Training Shanghai Second Medical University
Immunology and Cell Biology
M.Sc.
Residency Xin Hua Children's Hospital, Shanghai Second Medical University
Medicine
Resident
Professional Medical Shanghai Second Medical University
Medicine
M.D.

Global Impact

Education History

Type School Degree Country
Doctoral Training The University of New South Wales
Immunology & Molecular Biology
Ph.D. Australia
Fellowship Shanghai Institute for Pediatric Research, Shanghai Second Medical University
Medicine
Fellow China
Graduate Training Shanghai Second Medical University
Immunology and Cell Biology
M.Sc. China
Residency Xin Hua Children's Hospital, Shanghai Second Medical University
Medicine
Resident China
Professional Medical Shanghai Second Medical University
Medicine
M.D. China

Career

Institution Description Country
St. Vincent's Hospital, Center for Immunology Scientific Officer Australia