Karen C. Schliep, PhD, MSPH

Research Interests

  • Reproductive & Perinatal Epidemiology
  • Life Course Epidemiology
  • Biopsychosocial Mechanisms of Women's Health and Illness Using Time-Varying Covariates Across the Lifespan

Languages

  • English

Academic Information

  • Departments: Family and Preventive Medicine - Assistant Professor
  • Divisions: Public Health

Academic Bio

Karen Schliep, PhD, MSPH is an assistant professor in the Divison of Public Health. She completed her bachelor's degrees in English from Carleton College (Northfield, MN) and Biology from the Univeristy of Utah and her MSPH and PhD in Public Health from the University of Utah. Dr. Schliep completed her pre-doctoral and post-doctoral fellowship at the Eunice Kennedy Shriver National Institute of Child Health & Human Development (NICHD) Epidemiology Branch, where she served as an integral team member of several longitudinal studies including the BioCycle Study, the Endometriosis: Natural History, Diagnosis, and Outcomes (ENDO) Study, and the Effects of Aspirin on Gestation and Reproduction (EAGeR) Trial.

Dr. Schliep's research focuses on exploring the impact of diet, lifestyle, and psychosocial factors on female and male endocrinology and reproductive health; and understanding the short-and long-term consequences of abnormal reproductive function. Her overarching goal is to inform effective and individually tailored interventions for couples of reproductve age, which in turn may provide improved wellbeing and economic benefits for future generations.

Education History

Type School Degree
Research Fellow Eunice Kennedy Shriver National Institute of Child Health and Human Development
Epidemiology Branch
Postdoctoral Research Fellow
Doctoral Training University of Utah
Public Health
Ph.D.
Research Fellow Eunice Kennedy Shriver National Institute of Child Health and Human Development
Epidemiology Branch
Research Fellow
Graduate Training University of Utah
Public Health
M.S.P.H.
Undergraduate University of Utah
Biology; Minor: Chemistry
B.A.
Undergraduate Carleton College
English
B.A.

Global Impact

Presentations

Description Country
Risk Communication: Lessons Learned from Prior Outbreaks. The MERS-EBOLA Symposium. Hanyang University, Seoul, South Korea. Korea

Career

Institution Description Country
University of Utah, Asia Campus Assistant Professor Korea

Selected Publications

Journal Article

  1. Michels KA, Wactawski-Wende J, Mills JL, Schliep KC, Gaskins AJ, Yeung EH, Kim K, Plowden TC, Sjaarda LA, Chaljub EN, Mumford SL (2017). Folate, homocysteine and the ovarian cycle among healthy regularly menstruating women. Hum Reprod, 32(8), 1743-1750.
  2. Schliep KC, Chen Z, Stanford JB, Xie Y, Mumford SL, Hammoud AO, Boiman Johnstone E, Dorais JK, Varner MW, Buck Louis GM, Peterson CM (2017). Endometriosis diagnosis and staging by operating surgeon and expert review using multiple diagnostic tools: an inter-rater agreement study. BJOG, 124(2), 220-229.
  3. Theilen LH, Fraser A, Hollingshaus MS, Schliep KC, Varner MW, Smith KR, Esplin MS (2016). All-Cause and Cause-Specific Mortality After Hypertensive Disease of Pregnancy. Obstet Gynecol, 128(2), 238-44.
  4. Schliep KC (2016). Interpregnancy interval and preterm birth: correlation versus causation debate continued. BJOG, 123(12), 2018.
  5. Schliep KC, Mumford SL, Sjaarda LA, Schisterman EF (2016). In Reply. Obstet Gynecol, 127(6), 1171.
  6. Porucznik CA, Cox KJ, Schliep KC, Wilkins DG, Stanford JB (2016). The Home Observation of Periconceptional Exposures (HOPE) study, a prospective cohort: aims, design, recruitment and compliance. Environ Health, 15(1), 67.
  7. Schliep KC, Mumford SL, Johnstone EB, Peterson CM, Sharp HT, Stanford JB, Chen Z, Backonja U, Wallace ME, Buck Louis GM (2016). Sexual and physical abuse and gynecologic disorders. Hum Reprod, 31(8), 1904-12.
  8. Buck Louis GM, Backonja U, Schliep KC, Sun L, Peterson CM, Chen Z (2016). Women's Reproductive History Before the Diagnosis of Incident Endometriosis. J Womens Health (Larchmt), 25(10), 1021-1029.
  9. Mumford SL, Browne RW, Schliep KC, Schmelzer J, Plowden TC, Michels KA, Sjaarda LA, Zarek SM, Perkins NJ, Messer LC, Radin RG, Wactawski-Wende J, Schisterman EF (2016). Serum Antioxidants Are Associated with Serum Reproductive Hormones and Ovulation among Healthy Women. J Nutr, 146(1), 98-106.
  10. Schliep KC, Schisterman EF, Wactawski-Wende J, Perkins NJ, Radin RG, Zarek SM, Mitchell EM, Sjaarda LA, Mumford SL (2016). Serum caffeine and paraxanthine concentrations and menstrual cycle function: correlations with beverage intakes and associations with race, reproductive hormones, and anovulation in the BioCycle Study. Am J Clin Nutr, 104(1), 155-63.
  11. Johnson KA, Sjaarda LA, Mumford SL, Garbose RA, Schliep KC, Mattison D, Perkins NJ, Wactawski-Wende J, Schisterman EF (2016). Patterns and prevalence of medication use across the menstrual cycle among healthy, reproductive aged women. Pharmacoepidemiol Drug Saf, 25(6), 618-27.
  12. Schliep KC, Mitchell EM, Mumford SL, Radin RG, Zarek SM, Sjaarda L, Schisterman EF (2016). Trying to Conceive After an Early Pregnancy Loss: An Assessment on How Long Couples Should Wait. Obstet Gynecol, 127(2), 204-12.
  13. Mumford SL, Silver RM, Sjaarda LA, Wactawski-Wende J, Townsend JM, Lynch AM, Galai N, Lesher LL, Faraggi D, Perkins NJ, Schliep KC, Zarek SM, Schisterman EF (2016). Expanded findings from a randomized controlled trial of preconception low-dose aspirin and pregnancy loss. Hum Reprod, 31(3), 657-65.
  14. Mumford SL, Chavarro JE, Zhang C, Perkins NJ, Sjaarda LA, Pollack AZ, Schliep KC, Michels KA, Zarek SM, Plowden TC, Radin RG, Messer LC, Frankel RA, Wactawski-Wende J (2016). Dietary fat intake and reproductive hormone concentrations and ovulation in regularly menstruating women. Am J Clin Nutr, 103(3), 868-77.
  15. Zarek SM, Mitchell EM, Sjaarda LA, Mumford SL, Silver RM, Stanford JB, Galai N, Schliep KC, Radin RG, Plowden TC, DeCherney AH, Schisterman EF (2016). Antimullerian hormone and pregnancy loss from the Effects of Aspirin in Gestation and Reproduction trial. Fertil Steril, 105(4), 946-952.e2.
  16. Mumford SL, Silver RM, Sjaarda LA, Wactawski-Wende J, Townsend JM, Lynch AM, Galai N, Lesher LL, Faraggi D, Perkins NJ, Schliep KC, Zarek SM, Schisterman EF (2016). A randomized clinical trial of preconception low dose aspirin and pregnancy loss. Hum Reprod, 31(2016), 657-65.
  17. Shimony MK, Schliep KC, Schisterman EF, Ahrens KA, Sjaarda LA, Rotman Y, Perkins NJ, Pollack AZ, Wactawski-Wende J, Mumford SL (2016). The relationship between sugar-sweetened beverages and liver enzymes among healthy premenopausal women: a prospective cohort study. Eur J Nutr, 55(2), 569-576.
  18. Gorczyca AM, Sjaarda LA, Mitchell EM, Perkins NJ, Schliep KC, Wactawski-Wende J, Mumford SL (2016). Changes in macronutrient, micronutrient, and food group intakes throughout the menstrual cycle in healthy, premenopausal women. Eur J Nutr, 55(3), 1181-8.
  19. Schliep KC, Mumford SL, Ahrens KA, Hotaling JM, Carrell DT, Link M, Hinkle SN, Kissell K, Porucznik CA, Hammoud AO (2015). Effect of male and female body mass index on pregnancy and live birth success after in vitro fertilization. Fertil Steril, 103(2), 388-95.
  20. Schliep KC, Mumford SL, Vladutiu CJ, Ahrens KA, Perkins NJ, Sjaarda LA, Kissell KA, Prasad A, Wactawski-Wende J, Schisterman EF (2015). Perceived stress, reproductive hormones, and ovulatory function: a prospective cohort study. Epidemiology, 26(2), 177-84.
  21. Schisterman EF, Mumford SL, Schliep KC, Sjaarda LA, Stanford JB, Lesher LL, Wactawski-Wende J, Lynch AM, Townsend JM, Perkins NJ, Zarek SM, Tsai MY, Chen Z, Faraggi D, Galai N, Silver RM (2015). Preconception low dose aspirin and time to pregnancy: findings from the effects of aspirin in gestation and reproduction randomized trial. J Clin Endocrinol Metab, 100(5), 1785-91.
  22. Matyas RA, Mumford SL, Schliep KC, Ahrens KA, Sjaarda LA, Perkins NJ, Filiberto AC, Mattison D, Zarek SM, Wactawski-Wende J, Schisterman EF (2015). Effects of over-the-counter analgesic use on reproductive hormones and ovulation in healthy, premenopausal women. Hum Reprod, 30(7), 1714-23.
  23. Sjaarda LA, Schisterman EF, Schliep KC, Plowden T, Zarek SM, Yeung E, Wactawski-Wende J, Mumford SL (2015). Dietary Carbohydrate Intake Does Not Impact Insulin Resistance or Androgens in Healthy, Eumenorrheic Women. J Clin Endocrinol Metab, 100(8), 2979-86.
  24. Andrews MA, Schliep KC, Wactawski-Wende J, Stanford JB, Zarek SM, Radin RG, Sjaarda LA, Perkins NJ, Kalwerisky RA, Hammoud AO, Mumford SL (2015). Dietary factors and luteal phase deficiency in healthy eumenorrheic women. Hum Reprod, 30(8), 1942-51.
  25. Schliep KC, Mumford SL, Peterson CM, Chen Z, Johnstone EB, Sharp HT, Stanford JB, Hammoud AO, Sun L, Buck Louis GM (2015). Pain typology and incident endometriosis. Hum Reprod, 30(10), 2427-38.
  26. Radin RG, Mumford SL, Silver RM, Lesher LL, Galai N, Faraggi D, Wactawski-Wende J, Townsend JM, Lynch AM, Simhan HN, Sjaarda LA, Perkins NJ, Zarek SM, Schliep KC, Schisterman EF (2015). Sex ratio following preconception low-dose aspirin in women with prior pregnancy loss. J Clin Invest, 125(9), 3619-26.
  27. Schliep KC, Zarek SM, Schisterman EF, Wactawski-Wende J, Trevisan M, Sjaarda LA, Perkins NJ, Mumford SL (2015). Alcohol intake, reproductive hormones, and menstrual cycle function: a prospective cohort study. Am J Clin Nutr, 102(4), 933-42.
  28. Zarek SM, Mitchell EM, Sjaarda LA, Mumford SL, Silver RM, Stanford JB, Galai N, White MV, Schliep KC, DeCherney AH, Schisterman EF (2015). Is Anti-Mullerian Hormone Associated With Fecundability? Findings From the EAGeR Trial. J Clin Endocrinol Metab, 100(11), 4215-21.
  29. Wong LF, Schliep KC, Silver RM, Mumford SL, Perkins NJ, Ye A, Galai N, Wactawski-Wende J, Lynch AM, Townsend JM, Faraggi D, Schisterman EF (2015). The effect of a very short interpregnancy interval and pregnancy outcomes following a previous pregnancy loss. Am J Obstet Gynecol, 212(3), 375.e1-11.
  30. Prasad A, Schisterman EF, Schliep KC, Ahrens KA, Sjaarda LA, Perkins NJ, Matyas R, Wactawski-Wende J, Mumford SL (2014). Depressive symptoms and their relationship with endogenous reproductive hormones and sporadic anovulation in premenopausal women. Ann Epidemiol, 24(12), 920-4.
  31. Kissell KA, Danaher MA, Schisterman EF, Wactawski-Wende J, Ahrens KA, Schliep KC, Perkins NJ, Sjaarda LA, Mumford SL (2014). Variation in Serum anti-Müllerian Hormone throughout Ovulatory and Sporadic Anovulatory Cycles in Eumenorrheic Women. Hum Reprod, 29(8), 1764-72.
  32. Ahrens K, Mumford SL, Schliep KC, Kissell KA, Perkins NJ, Wactawski-Wende J, Schisterman EF (2014). Serum leptin levels and reproductive function during the menstrual cycle. Am J Obstet Gynecol, 210(3), 248.e1-9.
  33. Ahrens KA, Vladutiu CJ, Mumford SL, Schliep KC, Perkins NJ, Wactawski-Wende J, Schisterman EF (2014). The effect of physical activity across the menstrual cycle on reproductive function. Ann Epidemiol, 24(2), 127-34.
  34. Porucznik CA, Cox KJ, Schliep KC, Stanford JB (2014). Pilot test and validation of the peak day method of prospective determination of ovulation against a handheld urine hormone monitor. BMC Womens Health, 14, 4.
  35. Schliep KC, Mumford SL, Hammoud AO, Stanford JB, Kissell KA, Sjaarda LA, Perkins NJ, Ahrens KA, Wactawski-Wende J, Mendola P, Schisterman EF (2014). Luteal phase deficiency in regularly menstruating women: prevalence and overlap in identification based on clinical and biochemical diagnostic criteria. J Clin Endocrinol Metab, 99(6), E1007-14.
  36. Sjaarda LA, Mumford SL, Kissell K, Schliep KC, Hammoud AO, Perkins NJ, Weck J, Wactawski-Wende J, Schisterman EF (2014). Increased androgen, anti-Mullerian hormone, and sporadic anovulation in healthy, eumenorrheic women: a mild PCOS-like phenotype? J Clin Endocrinol Metab, 99(6), 2208-16.
  37. Lynch KE, Mumford SL, Schliep KC, Whitcomb BW, Zarek SM, Pollack AZ, Bertone-Johnson ER, Danaher M, Wactawski-Wende J, Gaskins AJ, Schisterman EF (2014). Assessment of anovulation in eumenorrheic women: comparison of ovulation detection algorithms. Fertil Steril, 102(2), 511-518.e2.
  38. Prasad A, Mumford SL, Buck Louis GM, Ahrens KA, Sjaarda LA, Schliep KC, Perkins NJ, Kissell KA, Wactawski-Wende J, Schisterman EF (2014). Sexual activity, endogenous reproductive hormones and ovulation in premenopausal women. Horm Behav, 66(2), 330-8.
  39. Schliep KC, Schisterman EF, Mumford SL, Pollack AZ, Perkins NJ, Ye A, Zhang CJ, Stanford JB, Porucznik CA, Hammoud AO, Wactawski-Wende J (2013). Energy-containing beverages: reproductive hormones and ovarian function in the BioCycle Study. Am J Clin Nutr, 97(3), 621-30.
  40. Schliep KC, Schisterman EF, Mumford SL, Perkins NJ, Ye A, Pollack AZ, Zhang C, Porucznik CA, VanDerslice JA, Stanford JB, Wactawski-Wende J (2013). Validation of different instruments for caffeine measurement among premenopausal women in the BioCycle study. Am J Epidemiol, 177(7), 690-9.
  41. Filiberto AC, Mumford SL, Pollack AZ, Zhang C, Yeung EH, Schliep KC, Perkins NJ, Wactawski-Wende J, Schisterman EF (2013). Usual dietary isoflavone intake and reproductive function across the menstrual cycle. Fertil Steril, 100(6), 1727-34.
  42. Tham E, Schliep K, Stanford J (2012). Outcomes of Natural Procreative Technology (NPT) in the Treatment of Infertility and Recurrent Miscarriage. Can Fam Physician, 58(5), e267-e274.
  43. Schliep KC, Schisterman EF, Mumford SL, Pollack AZ, Zhang C, Ye A, Stanford JB, Hammoud AO, Porucznik CA, Wactawski-Wende J (2012). Caffeinated beverage intake and reproductive hormones among premenopausal women in the BioCycle Study. Am J Clin Nutr, 95(2), 488-97.
  44. Schliep KC, Stanford JB, Chen Z, Zhang B, Dorais JK, Boiman Johnstone E, Hammoud AO, Varner MW, Louis GM, Peterson CM (2012). Interrater and intrarater reliability in the diagnosis and staging of endometriosis. Obstet Gynecol, 120(1), 104-12.
  45. Nassaralla CL, Stanford JB, Daly KD, Schneider M, Schliep KC, Fehring RJ (2011). Characteristics of the menstrual cycle after discontinuation of oral contraceptives. J Womens Health (Larchmt), 20(2), 169-77.
  46. Schliep K, Nanney M, Coffrin K, Anderson D (2010). Applying the Alliance for a Healthier Generation guidelines for competitive foods and beverages in Utah schools. Utah's Health: An Annual Review, 15.
  47. George DB, Davidson DW, Schliep KC, Patrell-Kim LJ (2000). Microtopography of microbiotic crusts on the Colorado Plateau and the distribution of component organisms. West N Am Nat, 60, 343-54.
  48. Radin RG, Sjaarda LA, Silver RM, Mumford SL, Perkins NJ, Wilcox JD, Pollack AZ, Schliep KC, Nobles CJ, Plowden TC, Schisterman EF (In Press). C-reactive protein in relation to fecundability and anovulation among eumenorrheic wome. Fertil Steril.

Book Chapter

  1. Mumford SL, Schliep KC, Prasad A, Schisterman EF (2014). The menstrual cycle and lipid levels. In Hollins-Martin C, van den Akker O, Martin C, Preedy VR (Eds.), Handbook of diet and nutrition in the menstrual cycle, periconception and fertility (pp. 239-54). Wageningen, The Netherlands: Wageningen Academic Publishers.

Commentary

  1. Schliep KC (July 2016). Invited Mini-Commentary: Interpregnancy interval and preterm birth: correlation versus causation debate continued. BJOG, 1471-0528, .14168.

Letter

  1. Schliep KC, Mumford SL, Sjaarda LA, Schisterman EF (2016). Invited Letter to the Editor: Authors' Response to Trying to Conceive After an Early Pregnancy Loss [Letter to the editor]. Obstet Gynecol, 127(6), 1171.
  2. Schliep K (2009). A call to provide multiple options for women in developing countries [Letter to the editor]. Fertil Steril, 92(2), e35.

Abstract

  1. Wong LF, Schliep KC, Schisterman EF, Wactawski-Wende J, Townsend JM, Lynch AM, Galai N, Faraggi D, Perkins NJ, Mumford SL, Ye A, Silver RM (2014). The Effect of Very Short Interpregnancy Interval on Pregnancy Outcomes After Early Pregnancy Loss. Poster session presented at Society for Maternal Fetal Medicine, New Orleans, LA [Abstract].
  2. Sjaarda L, Mumford S, Laughon SK, Kissell K, Schliep K, Wactawski-Wende J, Schisterman E (2013). Perturbations in testosterone are associated with sporadic anovulation in normally menstruating women [Abstract]. Society for Epidemiologic Research Annual Meeting, Boston MA.
  3. Schliep K, Mumford S, Albert P, Yeung E, Ye A, Schisterman E (2013). Application of Nonlinear Mixed Models with Harmonic Terms for Analyzing Longitudinal Data [Abstract]. Am J Epidemiol, 177(11 (Suppl)), S181.
  4. Kissell K, Danaher M, Schisterman EF, Perkins N, Schliep KC, Ahrens KA, Sjaarda LA, Wactawski-Wende J, Mumford SL (2013). The Impact of Serum anti-Müllerian Hormone on Follicular Phase Length in Premenopausal Women; also presented as a poster at Society for Epidemiologic Research Annual Meeting, Boston, MA [Abstract]. Am J Epidemiol, 177(11 Suppl), S149.
  5. Stanford JB, Schliep KC, Chen Z, Xie Y, Buck Louis GM, Peterson CM (2012). Comparability of endometriosis diagnosis and staging by operating surgeon and expert reviewer during real-time laparoscopy in the ENDO Study [Abstract]. Fertil Steril, 98(3), S216.
  6. Hammoud AO, Schliep KC, Mumford SL, Stanford JB, Porucznik CA, Schisterman EF (2012). Luteal phase deficiency in the BioCycle Study [Abstract]. Fertil Steril, 98(3), S25-26.
  7. Schliep K (2012). Exploring energy balance among postpartum adolescents [Abstract]. Am J Epidemiol, 175((11 Suppl)), S77.
  8. Porucznik CA, Schliep KC, Cox KJ, Willardson SL, Fang WB, Wilkins DG, Stanford JB (2012). Validation of a Caffeine Questionnaire with Salivary Biomarkers; also presented as a poster at Society for Epidemiologic Research Annual Meeting, Minneapolis, MN [Abstract]. Am J Epidemiol, 175(11 Suppl), S99.
  9. Schliep K, Stanford J, Chen Z, Zhang B, Dorais J, Johnstone E, Hammoud A, Varner M, Buck Louis G, Peterson CM (2012). Inter- and Intra-rater Reliability in the Diagnosis and Staging of Endometriosis; also presented as a poster at Society for Epidemiologic Research Annual Meeting, Minneapolis, MN [Abstract]. Am J Epidemiol, 175(11 Suppl), S137.
  10. Link MH, Schliep KC, Hammoud AO, Deshmukh R, Porucznik CA, Carrell DC (2012). Effects of paternal obesity on in vitro fertilization (IVF) pregnancy and live birth; also presented as a poster at American Society for Reproductive Medicine Annual Meeting, San Diego, CA [Abstract]. Fertil Steril, 98(3), S204.
  11. Porucznik CA, Schliep KC, Willardson SL, Stanford JB (2011). Validation of the Peak Day method of prospective determination of ovulation against a handheld urine hormone monitor; also presented as a poster at Society for Pediatric and Perinatal Epidemiologic Research Annual Meeting, Montreal, Canada [Abstract]. Am J Epidemiol, 173(11 Suppl), S44.
  12. Porucznik C, VanDerslice J, Panichello J, Schliep K, Firth S, Stanford J (2009). Demonstrating project: Using administrative data to estimate exposure to drinking water contaminants among women seeking to conceive; also presetned as a poster [Abstract]. Am J Epidemiol, 169(11 Suppl), S105.

Poster

  1. Sjaarda L, Mumford S, Yeung E, Schliep K, Wactawski-Wende J, Schisterman E (Spring 2014). Dietary carbohydrate intake and androgens in normally menstruating women. Poster session presented at Society for Pediatric and Perinatal Epidemiologic Research Annual Meeting, Seattle, WA.
  2. Zarek SM, DeCherney AH, Browne RW, Schisterman EF, Perkins NJ, Sjaarda L, Schliep KC, Ahrens K, Wactawski-Wende J, Mumford SL (Spring 2014). Relationship between luteal phase advanced lipoprotein particles and ovarian hormones in healthy, eumenorrheic women. Poster session presented at Society for Pediatric and Perinatal Epidemiologic Research Annual Meeting, Seattle, WA.
  3. Matyas RA, Mumford SL, Schliep KC, Ahrens KA, Sjaarda LA, Perkins NJ, Wactaswki Wende J, Schisterman EF (6/20/2014). Over-the-counter analgesic use effects on reproductive hormones and ovulation. Poster session presented at Society for Epidemiologic Research Annual Meeting, Seattle, WA.