Brian C. Sauer, PhD, MS

Research Interests

  • Quality of Medication Use
  • Health Care Quality and Patient Safety
  • Medical Informatics
  • Pharmacoepidemiology
  • Causal Inference

Languages

  • English

Academic Information

  • Departments: Biomedical Informatics - Adjunct Associate Professor, Family and Preventive Medicine - Adjunct Associate Professor, Internal Medicine - Associate Professor, Pharmacotherapy - Adjunct Assistant Professor, Population Health Sciences - Adjunct Associate Professor
  • Divisions: Biostatistics, Epidemiology, Public Health

Academic Office Information

  • 801-755-1955
  • Veterans Administration Medical Center
    SL IDEAS Center (182)
    500 S Foothill Blvd
    Salt Lake City, UT 84149

Academic Bio

My research interests include pharmacoepidemiology, comparative effectiveness research, medical informatics, and causal inference. My goals are to develop new knowledge and methods that improve the research process and realize them in applied research. We are accomplishing this by improving our theoretical understanding of research and causal inference. We are also developing methods to improve the transparency and reproducibility of our database research. I have received funding from the Veterans Health Administration and the Observational Medical Outcomes Partnership (OMOP) to develop Transparent ReUsable database and Statistical Tools (TRUST), which are analytic modules that execute specific data transformation and analytic tasks. Modules are compiled to develop workflows that can be automated, shared and reused by other investigators. We want to establish a social network of epidemiologists, biostatisticians and health services research for the purpose of collaborating and sharing research materials such as program code and analytic modules.I serve on multiple working groups to develop guidelines for database management and observational comparative effectiveness research. I have used my role as one of the COIN center analytic core leads to develop and implement templates and standard operating procedures for epidemiological data management. We are also developing principles of epidemiologic data management and a framework for integrating project plans across research teams and roles.

Education History

Type School Degree
Graduate Training University of Utah
Public Health Informatics
M.S.
Fellowship Veterans Affairs Medical Center
Medical Informatics
Fellow
Doctoral Training University of Florida
Pharmacoepidemiology
Ph.D.
Undergraduate University of Florida
Psychology (Biological)
B.S.

Selected Publications

Journal Article

  1. Lucila Ohno-Machado, Zia Agha, Douglas S Bell, Lisa Dahm, Michele E Day, Jason N Doctor, Davera Gabriel, Maninder K Kahlon, Katherine K Kim, Michael Hogarth, Michael E Matheny, Daniella Meeker, Jonathan R Nebeker, Frederic Resnic, Dmitry Khodyakov, Lattice Armstead, Travis Nagler, Sam Morley, Nicholas Anderson, Dan Cooper, Dan Phillips, David Heber, Zhaoping Li, Michael K Ong, Ayan Patel, Marianne Zachariah, Jane C Burns, Lori B Daniels, Son Doan, Claudiu Farcas, Rita Germann-Kurtz, Xiaoqian Jiang, Hyeon-eui Kim, Paulina Paul, Howard Taras, Adriana Tremoulet, Shuang Wang, Wenhong Zhu, Douglas Berman, Angela Rizk-Jackson, Mike DArcy, Carl Kesselman, Tara Knight, Laura Pearlman, Paul Heidenreich, Dena Rifkin, Carl Stepnowsky, Tania Zamora, Scott L DuVall, Lewis J Frey, Jeffrey Scehnet, Brian C Sauer, Julio C Facelli, Ram K Gouripeddi, Jason Denton, Fern FitzHenry, James Fly, Vincent Messina, Freneka Minter, Lalit Nookala, Heidi Sullivan, Theodore Speroff, Dax Westerman (04/29/2014). pSCANNER: patient-centered Scalable National Network for Effectiveness Research. J Am Med Inform Assoc, online, amiajnl-2014-00.
  2. Cannon GW, DuVall SL, Haroldsen CL, Caplan L, Curtis JR, Michaud K, Mikuls TR, Reimold A, Collier DH, Harrison DJ, Joseph GJ, Sauer BC (2014). Persistence and dose escalation of tumor necrosis factor inhibitors in US veterans with rheumatoid arthritis. J Rheumatol, 41(10), 1935-43.
  3. Johnson ES, Bartman BA, Briesacher BA, Fleming NS, Gerhard T, Kornegay CJ, Nourjah P, Sauer B, Schumock GT, Sedrakyan A, Sturmer T, West SL, Schneeweiss S (01/2013). The incident user design in comparative effectiveness research. Pharmacoepidemiol Drug Saf, 22(1), 1-6.
  4. Gundlapalli A, Divita G, Carter M, Shen S, Palmer M, Forbush T, South B, Redd A, Sauer B, Samore M (03/2013). Extracting Surveillance Data from Templated Sections of an Electronic Medical Note: Challenges and Opportunities. OJPHI, 5(1).
  5. Sauer BC, Brookhart MA, Roy J, VanderWeele T (2013). A review of covariate selection for non-experimental comparative effectiveness research. Pharmacoepidemiol Drug Saf, 22(11), 1139-45.
  6. Porucznik CA, Johnson EM, Rolfs RT, Sauer BC (2013). Opioid prescribing knowledge and practices: provider survey following promulgation of guidelines-Utah, 2011. J Opioid Manag, 9(3), 217-24.
  7. Cheng M, Sauer B, Johnson E, Porucznik C, Hegmann K (2013). Comparison of opioid-related deaths by work-related injury. Am J Ind Med, 56(3), 308-16.
  8. Sauer, BC, Helper CD (02/2013). Application of system-level root cause analysis for drug quality and safety problems: A case study. Res Social Adm Pharm, 9(1), 49-59.
  9. Johnson EM, Lanier WA, Merrill RM, Crook J, Porucznik CA, Rolfs RT, Sauer B (2013). Unintentional prescription opioid-related overdose deaths: description of decedents by next of kin or best contact, Utah, 2008-2009. J Gen Intern Med, 28(4), 522-9.
  10. Porucznik CA, Crook J, Johnson EM, Rolfs RT, Sauer BC (1/1/2014). Specialty of Prescribers Associated with Opioid Fatalities in Utah, 2002-2010. Pain Med, 15(1), 5.
  11. Hope CJ, Garvin JH, Sauer BC (2012). Information extraction from narrative data. Am J Health Syst Pharm, 69(6), 455, 460-1.
  12. Hall GC, Sauer B, Bourke A, Brown JS, Reynolds MW, LoCasale R (2012). Guidelines for good database selection and use in pharmacoepidemiology research. Pharmacoepidemiol Drug Saf, 21(1), 1-10.
  13. Nelson RE, Nebeker JR, Sauer BC, LaFleur J (2012). Factors associated with screening or treatment initiation among male United States veterans at risk for osteoporosis fracture. Bone, 50(4), 983-8.
  14. LaFleur J, Nelson RE, Sauer BC, Nebeker JR (2011). Overestimation of the effects of adherence on outcomes: a case study in healthy user bias and hypertension. Heart, 97(22), 1862-9.
  15. Cannon GW, Mikuls TR, Hayden CL, Ying J, Curtis JR, Reimold AM, Caplan L, Kerr GS, Richards JS, Johnson DS, Sauer BC (2011). Merging Veterans Affairs rheumatoid arthritis registry and pharmacy data to assess methotrexate adherence and disease activity in clinical practice. Arthritis Care Res (Hoboken), 63(12), 1680-90.
  16. Rubin MA, Mayer J, Greene T, Sauer BC, Hota B, Trick W, Jernigan JA, Samore MH (2008). An agent-based model for evaluating surveillance methods for catheter-related bloodstream infection. AMIA Annu Symp Proc, 631-5.
  17. Rupper RW, Bair BD, Sauer BC, Nebeker JR, Shinogle J, Samore M (2007). Out-of-pocket pharmacy expenditures for veterans under medicare part D. Med Care, 45(10 Supl 2), S77-80.
  18. Nebeker JR, Yarnold PR, Soltysik RC, Sauer BC, Sims SA, Samore MH, Rupper RW, Swanson KM, Savitz LA, Shinogle J, Xu W (2007). Developing indicators of inpatient adverse drug events through nonlinear analysis using administrative data. Med Care, 45(10 Supl 2), S81-8.
  19. Samore, MH, Shen, S, Greene, T, Stoddard, G, Sauer, B, Shinogle, J, Nebeker, J, Harbarth, S (2007). A Simulation-based Evaluation of Methods to Estimate the Impact of an Adverse Event on Hospital Length of Stay. Medical Care, 45(10 (Supl 2)), S108-15.

Book Chapter

  1. Sauer B, Vanderweele T (2/2013). Supplement 2: The Use of Directed Acyclic Graphs on Non-experimental Comparative Effectiveness Research. In Velentgas P, Dreyer NA, Nourjah P, Smith SR, Torchia MM (Eds.), Developing a Protocol for Observational Comparative Effectiveness Research: A Users Guide. Rockville: Agency for Healthcare Research and Quality.
  2. Sauer B, Brookhart MA, Roy JA, VanderWeele TJ (02/2013). Chapter 7: Covariate Selection. In Velentgas P, Dreyer NA, Nourjah P, Smith SR, Torchia MM (Eds.), Developing a Protocol for Observational Comparative Effectiveness Research: A Users Guide. Rockville: Agency for HealthCare Research and Quality.

Conference Proceedings

  1. Sauer BC, Nebeker JR, Shen S, Rupper R, Samore M (2011). Identification of possible adverse drug reactions using population-based administrative data. In Faculty of Pharmaceutical Sciences, Ubon Ratchathani University, Thailand (Eds.), Patient Safety Annu Symp, Ubon, Thailand: ISBN 978-974-523-265-5 (Thailand), Proc. 2011, 60-66.
  2. Gundlapalli A, Divita G, Carter M, Shen S, Palmer M, Forbush T, South B, Redd A, Sauer B, Samore M (01/2013). Online Journal of Public Health Informatics. OJPHI, 5(1).
  3. Sauer, BC, He Tao, Nebeker JR (04/30/2013). SAS® Tools for Transparent and Reproducible Research: Medication History Estimator. SAS® Global Forum 2013 proceedings, San Francisco: SAS®, 1-10.
  4. Sauer BC, Nebeker JR, Shen S, Rupper R, Samore M (2011). Identification of possible adverse drug reactions using population-based administrative data. In Faculty of Pharmaceutical Sciences, Ubon Ratchathani University, Thailand (Eds.), Patient Safety Annu Symp, Ubon, Thailand: ISBN 978-974-523-265-5 (Thailand), Proc. 2011, 60-66.
  5. Sauer B, Nebeker J, Rupper R, Samore M (2007). Serum Potassium Monitoring and Hyperkalemia in Veterans using Renin-Angiotensin-Aldosterone Inhibitors. HSR&D National Meeting, Arlington, VA.

Abstract

  1. Ghate SR, LaFleur J, Sauer B, Charland S (2008). A modified RxRisk-V comorbidity index predicts adherence with lipid lowering therapy. (Poster session presented at International Society for Pharmacoeconomics and Outcomes Research 13th Annual International Meeting. Toronto, Ontario, Canada. May 2008) [Abstract]. Value In Health, 11(3), A185.
  2. LaFleur J, Ghate S, Sauer B (05/2008). Updating the RxRisk-V measure: Creating a crosswalk between Veterans Affairs pharmacy codes and First Databank therapeutic categories [Abstract]. Value in Health, 11(3), A191.

Report

  1. Sauer BC, Shinogle JA, Xu W, Samore M, Nebeker J, Liu Z, Rupper R, Lux L, Amoozegar J, Lohr KN (August 2008). Improving Patient Safety and Pharmacovigilance: Methods Using Observational Data and Cohort Studies (Number 6). Agency for Healthcare Research and Quality.

Poster

  1. DuVall SL, Sauer BC, Robison RJ, Halls CH, Forbush TB, Lu CC, Kamauu AG, Dastrup E, Chen E, Villa K, Kamauu AWC (2014). Survey of Central Venous Access Device Management Policies Across Two US Healthcare Systems. Poster session presented at 2014 Association for Vascular Access Annual Scientific Meeting, National Harbor, MD.
  2. A Gundlapalli, G Divita, M Carter, S Shen, M Palmer, T Forbush, B South, A Redd, B Sauer, M Samore (10/2012). Proceedings of the 2012 ISDS Conference - Expanding Collaborations to Chart a New Course in Public Health Surveillance - San Diego, CA, December 4-5, 2012 - Oral Presentation: Syndrome Development and Validation and Natural Language Processing.
  3. DuVall SL, Kamauu AWC, Sauer BC (06/2012). Using Advanced Healthcare Data Analytics to Identify and Characterize Central Venous Catheterization Episodes via Electronic Health Records in the Veterans Affairs Database. Poster session presented at 17th Annual Meeting of the International Society for Pharmacoeconomics and Outcomes Research, Washington, D.C..
  4. Sauer B, DuVall S (06/2012). Development of a Modified RxRisk Score. Poster session presented at ISPOR 17th Annual International Meeting, Washington DC.
  5. Duvall SL, Kamauu AWC, Sauer BC (06/2012). PMD56 Using Advanced Health Care Data Analytics to Identify and Characterize Central Venous Catheterization Episodes via Electronic Health Records in the Veterans Affairs.
  6. Greene T, Rubin M, Nebeker J, Sauer B, and Samore MH (2009). Evaluation of diagnostic classification procedures when the available evidence is limited. Poster session presented at 27th VA Health Services Research and Development (HSR&D) Service National Meeting, Baltimore, MD.
  7. LaFleur J, Nelson R, Sauer B, Sheng X, Pickard S, Ong SH, Brixner D, Nebeker J (11/2009). Any-cause hospitalization outcomes associated with poor patient adherence to antihypertensives.
  8. Greene T, Samore MH, Mayer J, Sauer B, and Rubin MA (2008). Objective simplified surveillance criteria improve comparisons of central line-associated blood stream infection (CLA-BSI) rates between institutions. Poster session presented at 26th VA Health Services Research and Development Service (HSR&D) National Meeting, Baltimore, MD.
  9. LaFleur J, Ghate S, Sauer B (06/2008). PCV20 Updating the RxRisk-V: Creating a crosswalk between VA and FirstDataBank therapeutic categories.
  10. Rubin MA, Sauer B, Mayer J, Greene T, Stoddard G, Hota B, Trick W, Samore MH (10/2007). AN AGENT-BASED MODELING APPROACH TO SURVEILLANCE OF CATHETER-RELATED BLOODSTREAM INFECTIONS. Poster session presented at The 29th Annual Meeting of the Society for Medical Decision Making, Pittsburgh.
  11. Sauer BC, Kapoor D, Nebeker J, Beddhu S, Samore MH (2006). Factors Associates with Serum Potassium Monitoring in Veterans using Renin-Angiotensin-Aldosterone inhibitors. Poster session presented at 24th HSR&D National Meeting, Crystal City, Arlington, VA.

Video