Samuel M. Brown, MD, MS


  • English
  • Russian
  • Spanish

Academic Information

  • Departments: Internal Medicine - Associate Professor
  • Divisions: Pulmonary

Board Certification

  • American Board of Internal Medicine (Sub: Pulmonary Disease)
  • American Board of Internal Medicine (Sub: Critical Care Medicine)

Academic Office Information

  • 801-507-6556
  • Intermountain Medical Center
    Shock Trauma ICU
    5121 Cottonwood Street
    Murray, UT 84107

Academic Bio

Dr. Brown is an NIH-funded researcher studying the body’s response to life-threatening infection. He is also assistant director of critical care echocardiography at Intermountain Medical Center. He has published widely on pneumonia, sepsis, and critical care echocardiography. Dr. Brown serves on the Ultrasound Certification Task Force for the Society of Critical Care Medicine and is frequent faculty at national and international courses on critical care ultrasound and echocardiography. Dr. Brown is also a respected medical humanist and ethicist with a special interest in embodiment, sickness, and the end-of-life.Dr. Brown graduated summa cum laude from Harvard College (Linguistics and Russian) then graduated from Harvard Medical School and completed internship and residency at Massachusetts General Hospital. He studied global health with an emphasis on the Former Soviet Union during medical school and residency, then transitioned to his work on sepsis with fellowship training at the University of Utah.Dr. Brown’s research emphasizes management of sepsis and shock, and he participates in the ARDS Network research group studying acute lung injury. He has received federal and foundation funding for various studies trying to understand how subtle rhythms or patterns in heart rate, blood pressure, and other measurements of heart function might predict how well a patient will respond to a particular therapy. Dr. Brown’s group includes academic investigators in engineering, mathematical biology, epidemiology, and bench research. He has published and lectured widely on these topics.

Education History

Type School Degree
Fellowship University of Utah School of Medicine/SLC VA Hospital, Department of Anesthesia
Transthoracic Echocardiography
Graduate Training University of Utah
Clinical Investigation
Fellowship University of Utah
Pulmonary and Critical Care Medicine
Residency Massachusetts General Hospital
Internal Medicine
Internship Massachusetts General Hospital
Internal Medicine
Professional Medical Harvard Medical School
Undergraduate Harvard College
Linguistics and Russian

Selected Publications

Journal Article

  1. Brown SM, Grissom CK, Moss M, Rice TW, Schoenfeld D, Hou PC, Thompson BT, Brower RG (2016). Nonlinear Imputation of Pao2/Fio2 From Spo2/Fio2 Among Patients With Acute Respiratory Distress Syndrome. Chest, 150(2), 307-13.
  2. Walkey AJ, Pencina KM, Knox D, Kuttler KG, DAgostino RB Sr, Benjamin EJ, Brown SM (2015). Five-Year Risk of Mechanical Ventilation in Community-Dwelling Adults: The Framingham-Intermountain Anticipating Life Support Study. J Am Geriatr Soc, 63(10), 2082-8.
  3. Lanspa MJ, Pittman JE, Hirshberg EL, Wilson EL, Olsen T, Brown SM, Grissom CK (2015). Association of left ventricular longitudinal strain with central venous oxygen saturation and serum lactate in patients with early severe sepsis and septic shock. Crit Care, 19(1), 304.
  4. Knox DB, Lanspa MJ, Kuttler KG, Brewer SC, Brown SM (2015). Phenotypic clusters within sepsis-associated multiple organ dysfunction syndrome. Intensive Care Med, 41(5), 814-22.
  5. Pratt CM, Hirshberg EL, Jones JP, Kuttler KG, Lanspa MJ, Wilson EL, Hopkins RO, Brown SM (2015). Long-term outcomes after severe shock. Shock, 43(2), 128-32.
  6. Grissom CK, Hirshberg EL, Dickerson JB, Brown SM, Lanspa MJ, Liu KD, Schoenfeld D, Tidswell M, Hite RD, Rock P, Miller RR 3rd, Morris AH (2015). Fluid management with a simplified conservative protocol for the acute respiratory distress syndrome*. Crit Care Med, 43(2), 288-95.
  7. Brown SM, Grissom CK, Rondina MT, Hoidal JR, Scholand MB, Wolff RK, Morris AH, Paine R 3rd (2015). Polymorphisms in key pulmonary inflammatory pathways and the development of acute respiratory distress syndrome. Exp Lung Res, 41(3), 155-62.
  8. Rondina MT, Carlisle M, Fraughton T, Brown SM, Miller RR 3rd, Harris ES, Weyrich AS, Zimmerman GA, Supiano MA, Grissom CK (2015). Platelet-monocyte aggregate formation and mortality risk in older patients with severe sepsis and septic shock. J Gerontol A Biol Sci Med Sci, 70(2), 225-31.
  9. Brown SM, Tate MQ, Jones JP, Kuttler KG, Lanspa MJ, Rondina MT, Grissom CK, Mathews VJ (2015). Coefficient of Variation of Coarsely Sampled Heart Rate is Associated With Early Vasopressor Independence in Severe Sepsis and Septic Shock. J Intensive Care Med, 30(7), 420-5.
  10. Brown SM, Tate Q, Jones JP, Knox DB, Kuttler KG, Lanspa M, Rondina MT, Grissom CK, Behera S, Mathews VJ, Morris A (2013). Initial fractal exponent of heart rate variability is associated with success of early resuscitation in patients with severe sepsis or septic shock: a prospective cohort study. J Crit Care, 28(6), 959-63.
  11. Brown SM, Lanspa MJ, Jones JP, Kuttler KG, Li Y, Carlson R, Miller RR 3rd, Hirshberg EL, Grissom CK, Morris AH (2013). Survival after shock requiring high-dose vasopressor therapy. Chest, 143(3), 664-671.
  12. Miller RR 3rd, Dong L, Nelson NC, Brown SM, Kuttler KG, Probst DR, Allen TL, Clemmer TP (2013). Multicenter implementation of a severe sepsis and septic shock treatment bundle. Am J Respir Crit Care Med, 188(1), 77-82.
  13. Brown SM, Pittman J, Miller Iii RR, Horton KD, Markewitz B, Hirshberg E, Jones J, Grissom CK (2011). Right and left heart failure in severe H1N1 influenza A infection. Eur Respir J, 37(1), 112-8.

Edited Book

  1. Brown SM, Blaivas M, Hirshberg E, Kasal J, Pustavoitau A (Eds.) (2015). Comprehensive Critical Care Ultrasound. Chicago, IL: Society of Critical Care Medicine.