Matthew A. Williams, PhD
- Cancer Vaccines
- Viral infections
- Immunologic Memory
- Bacterial Infections
- T Cell Biology
- Departments: Pathology - Associate Professor
- Divisions: Microbiology and Immunology
- Cancer Center Programs: Cell Response & Regulation
Academic Office Information
Emma Eccles Jones Research Building
Department of Pathology
15 North Medical Drive East, Room: 2200J
Salt Lake City, UT 84112
|Postdoctoral Fellowship||University of Washington
|Doctoral Training||Emory University
|Undergraduate||Brigham Young University
- Kim C, Jay DC, Williams MA (2014). Dynamic functional modulation of CD4+ T cell recall responses is dependent on the inflammatory environment of the secondary stimulus. PLoS Pathog, 10(5), e1004137.
- Mitchell DM, Williams MA (2013). Disparate roles for STAT5 in primary and secondary CTL responses. J Immunol, 190(7), 3390-8.
- Jay DC, Mitchell DM, Williams MA (2013). Bim mediates the elimination of functionally unfit Th1 responders from the memory pool. PLoS One, 8(6), e67363.
- Kim C, Wilson T, Fischer KF, Williams MA (2013). Sustained interactions between T cell receptors and antigens promote the differentiation of CD4(+) memory T cells. Immunity, 39(3), 508-20.
- Khanolkar A, Williams MA, Harty JT (2013). Antigen experience shapes phenotype and function of memory Th1 cells. PLoS One, 8(6), e65234.
- Eyob H, Ekiz HA, Derose YS, Waltz SE, Williams MA, Welm AL (2013). Inhibition of ron kinase blocks conversion of micrometastases to overt metastases by boosting antitumor immunity. Cancer Discov, 3(7), 751-60.
- Kim C, Jay DC, Williams MA (2012). Stability and function of secondary Th1 memory cells are dependent on the nature of the secondary stimulus. J Immunol, 189(5), 2348-55.
- Shakya A, Kang J, Chumley J, Williams MA, Tantin D (2011). Oct1 is a switchable, bipotential stabilizer of repressed and inducible transcriptional states. J Biol Chem, 286(1), 450-9.
- Mitchell DM, Ravkov EV, Williams MA (2010). Distinct roles for IL-2 and IL-15 in the differentiation and survival of CD8+ effector and memory T cells. J Immunol, 184(12), 6719-30.
- Ravkov EV, Williams MA (2009). The magnitude of CD4+ T cell recall responses is controlled by the duration of the secondary stimulus. J Immunol, 183(4), 2382-9.
- Williams MA, Ravkov EV, Bevan MJ (2008). Rapid culling of the CD4+ T cell repertoire in the transition from effector to memory. Immunity, 28(4), 533-45.
- Williams MA, Tyznik AJ, Bevan MJ (2006). Interleukin-2 signals during priming are required for secondary expansion of CD8+ memory T cells. Nature, 441(7095), 890-3.
- Williams MA, Schmidt RL, Lenz LL (2012). Early events regulating immunity and pathogenesis during Listeria monocytogenes infection. [Review]. Trends Immunol, 33(10), 488-95.
- Kim C, Williams MA (2010). Nature and nurture: T-cell receptor-dependent and T-cell receptor-independent differentiation cues in the selection of the memory T-cell pool. [Review]. Immunology, 131(3), 310-7.
- Prlic M, Williams MA, Bevan MJ (2007). Requirements for CD8 T-cell priming, memory generation and maintenance. [Review]. Curr Opin Immunol, 19(3), 315-9.
- Williams MA, Bevan MJ (2007). Effector and memory CTL differentiation. [Review]. Annu Rev Immunol, 25, 171-92.
- Williams MA, Holmes BJ, Sun JC, Bevan MJ (2006). Developing and maintaining protective CD8+ memory T cells. [Review]. Immunol Rev, 211, 146-53.