Danny Hung-Chieh Chou, PhD

Labs

Lab Website

Languages

  • English
  • Mandarin
  • Taiwanese

Academic Information

  • Departments: Biochemistry - Assistant Professor, Pharmaceutics and Pharmaceutical Chemistry - Adjunct Assistant Professor

Education History

Type School Degree
Postdoctoral Fellowship Massachusetts Institute of Technology
Postdoctoral Fellow
Doctoral Training Harvard University
Chemistry & Chemical Biology
Ph.D.
Undergraduate National Taiwan University
Chemistry
B.S.

Global Impact

Education History

Type School Degree Country
Undergraduate National Taiwan University
Chemistry
B.S. Taiwan

Selected Publications

Journal Article

  1. Wang Y, Chou DH (2015). A Thiol-Ene Coupling Approach to Native Peptide Stapling and Macrocyclization. Angew Chem Int Ed Engl, 54(37), 10931-4.
  2. Chou DH, Webber MJ, Tang BC, Lin AB, Thapa LS, Deng D, Truong JV, Cortinas AB, Langer R, Anderson DG (2015). Glucose-responsive insulin activity by covalent modification with aliphatic phenylboronic acid conjugates. Proc Natl Acad Sci U S A, 112(8), 2401-6.
  3. Chou DH, Vetere A, Choudhary A, Scully SS, Schenone M, Tang A, Gomez R, Burns SM, Lundh M, Vital T, Comer E, Faloon PW, Dancik V, Ciarlo C, Paulk J, Dai M, Reddy C, Sun H, Young M, Donato N, Jaffe J, Clemons PA, Palmer M, Carr SA, Schreiber SL, Wagner BK (2015). Kinase-Independent Small-Molecule Inhibition of JAK-STAT Signaling. J Am Chem Soc, 137(24), 7929-34.
  4. Chou DH, Holson EB, Wagner FF, Tang AJ, Maglathlin RL, Lewis TA, Schreiber SL, Wagner BK (2012). Inhibition of histone deacetylase 3 protects beta cells from cytokine-induced apoptosis. Chem Biol, 19(6), 669-73.
  5. Chou DH, Bodycombe NE, Carrinski HA, Lewis TA, Clemons PA, Schreiber SL, Wagner BK (2010). Small-Molecule Suppressors of Cytokine-Induced beta-Cell Apoptosis. ACS Chem Biol, 5(8), 729-34.

Book Chapter

  1. Faloon PW, Chou DHC, Forbeck EM, Walpita D, Morgan B, Buhrlage S, Ting A, Perez J, MacPherson LJ, Duvall JR, Dandapani S, Marcaurelle LA, Munoz B, Palmer M, Foley M, Wagner B, Schreiber SL (2010). Identification of Small Molecule Inhibitors that Suppress Cytokine-Induced Apoptosis in Human Pancreatic Islet CellsBTI - Probe Reports from the NIH Molecular Libraries Program. Bethesda (MD).

Patent

  1. Wagner BK, Duvall JR, Chou DHC (2012). Compounds and Methods for Treating Autoimmune Diseases. U.S. Patent No. 2012061754. Washington, D.C.:U.S. Patent and Trademark Office.

Poster

  1. Chou DHC, Webber MJ, Tang BC, Veiseh O, Lin A, Deng Z, Loo W, Langer RS, Anderson DG (2013). Development of Modified Insulin Derivatives with Glucose-Sensing Moieties. Poster session presented at Gordon Research Conference, New London, NH.
  2. Chou DHC, Schreiber SL, Wagner BK (2009). Inhibition of GSK3? Protects Pancreatic Beta Cells From Cytokine-Induced Apoptosis. Poster session presented at 3rd Nature Chemical Biology Symposium, Boston, MA.

News

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