Internal Medicine Department
Hematology Division

James P. Kushner, MD

Email:    james.kushner@hsc.utah.edu

Education:

1958 – 1962    M.D., University of Pittsburgh, School of Medicine, Pittsburgh, Pennsylvania

1957 – 1958    New York University Graduate School of Arts and Science, New York, New York

1953 – 1957    B.A., Bowdoin College, Brunswick, Maine

Training:

1969 – 1970    Research Fellow in Hematology, College of Medicine, University of Utah, Salt Lake City, Utah

1967 – 1969    Clinical Fellow in Hematology, College of Medicine, University of Utah, Salt Lake City, Utah

1965 – 1967    Resident in Medicine, Presbyterian-University Hospital, Pittsburgh, Pennsylvania

1962 – 1963    Intern in Medicine, Presbyterian-St. Luke's Hospital, Chicago, Illinois

Research Interests:

Porphyrin Biosynthesis in Normal and Disease States
Hereditary Hemochromatosis

Recent Publications

  1. Abraham D, Rogers J, Gault P, Kushner JP, McClain DA. (2006). Increased insulin secretory capacity but decreased insulin sensitivity after correction of iron overload by phlebotomy in hereditary haemochromatosis. Diabetologia, 49(11), 2546-51.
  2. Ajioka RS, Phillips JD, Kushner JP. (2006). Biosynthesis of heme in mammals. Biochimica et Biophysica Acta, 1763(7), 723-36.
  3. McClain DA, Abraham D, Rogers J, Brady R, Gault P, Ajioka R, Kushner JP. (2006). High prevalence of abnormal glucose homeostasis secondary to decreased insulin secretion in individuals with hereditary haemochromatosis. Diabetologia, 49(7), 1661-9.
  4. Smith MW, Walters KA, Korth MJ, Fitzgibbon M, Proll S, Thompson JC, Yeh MM, Shuhart MC, Furlong JC, Cox PP, Thomas DL, Phillips JD, Kushner JP, Fausto N, Carithers RL Jr, Katze MG. (2006). Gene expression patterns that correlate with hepatitis C and early progression to fibrosis in liver transplant recipients. Gastroenterology, 130(1), 179-87.
  5. Phillips JD, Warby CA, Kushner JP. (2005). Identification of a novel mutation in the L-ferritin IRE leading to hereditary hyperferritinemia-cataract syndrome. Am J Med Genet A.
  6. Anderson KE, Bloomer JR, Bonkovsky HL, Kushner JP, Pierach CA, Pimstone NR, Desnick RJ. (2005). Recommendations for the Diagnosis and Treatment of the Acute Porphyrias. Ann Intern Med, 142(15), 439-50.
  7. Phillips JD, Warby CA, Kushner JP. (2005). Identification of a novel mutation in the L-ferritin IRE leading to hereditary hyperferritinemia-cataract syndrome. Am J Med Genet A, 134(1), 77-9.
  8. Cooksey RC, Jouihan HA, Ajioka RS, Hazel MW, Jones DL, Kushner JP, McClain DA. (2004). Oxidative stress, beta-cell apoptosis, and decreased insulin secretory capacity in mouse models of hemochromatosis. Endocrinology, 145(11), 5305-12.
  9. Phillips JD, Whitby FG, Warby CA, Labbe P, Yang C, Pflugrath JW, Ferrara JD, Robinson H, Kushner JP, Hill CP. (2004). Crystal structure of the oxygen-dependant coproporphyrinogen oxidase (Hem13p) of Saccharomyces cerevisiae. J Biol Chem, 279(37), 38960-8.