Department of Neurology

Fumisuke (Fred) Matsuo, MD

Clinical Professor of Neurology

Education:

  • Medical School: Kyoto Prefectural University of Medicine (1962-1968, Kyoto City. Kyoto, Japan)
  • Internship:  U. S. Army Hospital, Camp Zama (1968-1969. Camp Zama, Japan), Philadelphia General Hospital (1969-1970. Philadelphia, PA) 
  • Neurology Residency: University of Iowa Hospitals & Clinics (1970-1973. Iowa City, IA) 
  • Clinical Neurophysiology Fellowship: University of Iowa Hospitals & Clinics (1973. Iowa City, IA)

Clinical Interests:

  • Epilepsy-Clinical Neurophysiology

Research Interests:

  • Objectifying waveform criteria to identify focal EEG epileptiform discharges
  • Correlation of interictal epileptiform discharges between EEG and MEG 
  • Development of grading criteria for sequential visual analysis of prolonged EEG  
  • Assessment of the reliability of the diagnosis of psychogenic nonepileptic seizures
  • Examination of consciousness domain of the epileptologist utilizing “deja-vu” as the target symptom

Membership:

  • American Academy of Neurology (Fellow)
  • American Epilepsy Society
  • American Clinical Neurophysiology Society

Selected Publications

  • Matsuo F, Peters JF, Reilly EL. (1975). Electrical phenomena associated with movements of the eyelid. Electroencephalogr Clin Neurophysiol, 38(5), 507-11.
  • Matsuo F. (1976). Absence of Bell phenomenon during a blink. Arch Neurol, 33, 662.
  • Matsuo F, Knott JR. (1977). Focal positive spikes in electroencephalography. Electroencephalogr Clin Neurophysiol, 42(1), 15-25.
  • Matsuo F, Ajax ET. (1979). Palatal myclonus and denervation supersensitivity in the central nervous system. Ann Neurol, 5, 72-8.
  • Matsuo F. (1981). Recognition of REM sleep in standard EEG. Electroencephalogr Clin Neurophysiol, 52(5), 490-3
  • Matsuo F. (1985). EEG features of the apallic syndrome resulting from cerebral anoxia. Electroencephalogr Clin Neurophysiol, 61(2), 113-22.
  • Matsuo F. (1991). Expanded head surface EEG electrode array: an application to display the voltage topography of focal epileptiform discharges of mesiotemporal origin. J Clin Neurophysiol, 8(4), 442-51.
  • Matsuo F, Bergen D, Faught E, Messenheimer JA, Dren AT, Rudd GD, Lineberry CG. (1993). Placebo-controlled study of the efficacy and safety of lamotrigine in patients with partial seizures. U.S. Lamotrigine Protocol 0.5 Clinical Trial Group. Neurology, 43(11), 2284-91.
  • Matsuo F, Gay P, Madsen J, Tolman KG, Rollins DE, Risner ME, Lai AA. (1996). Lamotrigine high-dose tolerability and safety in patients with epilepsy: a double-blind, placebo-controlled, eleven-week study. Epilepsia, 37(9), 857-62.
  • Dreifuss FE, Rosman NP, Cloyd JC, Pellock JM, Kuzniecky RI, Lo WD, Matsuo F, Sharp GB, Conry JA, Bergen DC, Bell WE. (1998).  A comparison of rectal diazepam gel and placebo for acute repetitive seizures. N Eng J Med, 338(26), 1869-75.
  • Matsuo F. (2002).  A case of familial epilepsy with nocturnal recurrences. In.  Schmidt D, Schacter SC (Eds.), 110 Puzzling Cases of Epilepsy (pp. 331-3). London: Martin Dunitz.
  • Rodin E, Funke M, Berg P, Matsuo F. (2004). Magnetoencephalographic spikes not detected by conventional electroencephalography. Clin Neurophysiol, 115(9), 2041-7.
  • Matsuo F. (2009). Lamotrigine. In Shorvon S, Perucca E, Fish D, Dodson E (Eds.), The Treatment of Epilepsy 3rd Ed. Oxford: Blackwell Publishing. (in press)