Department of Physiology

Courses

5200 Principles of Physiology (5) Physiological principles and basic physiology of major organ systems including nervous, cardiovascular, respiratory, gastrointestinal, endocrine and renal. Open to science students.

5300 Techniques in Molecular Physiology (2-6) Cross-listed as PHYSL 6300.  This laboratory is designed to provide an understanding of basic and advanced molecular techniques used to study physiological systems from PCR, cloning, RNA isolation to designing transgenic models.  This course is suitable for undergraduate students.  Materials will be designed around each student's level of expertise.

6000 Systemic Physiology I (4) Cross-linked as BIOEN 6000.  Open to medical and other graduate students.  Emphasizes physiological principles of major organ systems such as neurology and endocrine physiology.  Course includes one credit hour lab work covering material in lecture.

6003 Cellular Biophysics and Electrophysiology (3) Cross-linked as BIOEN 6003.  This is the expanded cellular component of BE 6460. Covers membrane and cellular biophysics and electrophysiology of excitable membranes in heart and brain. BE 6460 has been successful course for 5 years and this course is response to the demand for more coverage of cellular and membrane components, including both experimental and simulation/modeling aspects of the field. This course will be required component of new track in Bioengineering.

6010 Systemic Physiology II (3) Cross-linked as BIOEN 6010.  Prereq.: BIOEN 3102 or equivalent.  Open to medical and other graduate students.  Emphasizes physiological principles of major organ systems such as neurology and endocrine physiology.

6040 Cellular and Molecular Neuroscience (4).  Cross-linked as NEUSC 6040 or BIOL 6040.  The bulk of this course will focus on the cellular mechanisms of signaling.  The topics to be covered include basic neuronal/glial morphology and cell biology; neurostructural mapping and identification; basic neural development; cytoskeleton-structure and biochemistry; basic membrane biophysics; cable properties; ion channel biophysics and molecular biology; synaptic transmission; neurotransmitter gated ionotropic systems; and neurotransmitter gated metabotropic systems.

6050 General Physiology (2) Required of first-year medical students. Physiology of the cell with emphasis on physiological principles germane to various organ systems. Lectures and case presentations.

6070 Systemic Physiology (10) Required of second-year students. General physiologic principles, physiology of nervous, cardiovascular, respiratory, nervous, renal, endocrine and gastrointestinal systems. Lectures, laboratories and case presentations. Graduate students register for PHYSL 6020.

6200 Principles of Physiology (5) Cross-linked as PHYSL 5200.  Physiological principles and basic physiology of major organ systems including nervous, cardiovascular, respiratory, gastrointestinal, endocrine and renal. Open to science students.

6245 Cellular and Molecular Neurophysiology Laboratory (2) Cross-linked as BIOL 6245, NEUSC 6245.  Electrophysiology and video microscopy study of nerve, muscle, and synapse.  (Meets M-F 8AM-9AM for one week before the start of Fall Semester.)

6300 Techniques in Molecular Physiology (2-6) Cross-linked as PHYSL 5300.  This laboratory is designed to provide an understanding of basic and advanced molecular techniques used to study physiological systems from PCR, cloning, RNA isolation to designing transgenic models.  This course is suitable for undergraduate students.  Materials will be designed around each student's level of expertise.

6460 Electrophysiology and Bioelectricity (3) Cross-linked as BIOEN 6460.  The goal of this class is to provide an overview of electrophysiology and bioelectricity to graduate students with special interest in cardiology and neurosciences. We will develop the central electrical mechanisms from the membrane channel to the intact organ, building on those that are common to many electrically active cells in the body. The approach will be a combination of qualitative explanations, quantitative analysis, and mathematical simulation. The class format will include didactic lectures, group discussion of primary literature, student presentations, quantitative problem solving exercises, writing assignments, and laboratory experiences. The prerequisite for the course is the permission of the instructor; strongly recommended background knowledge includes previous exposure to basic electrophysiology (e.g., PHYSL 6000 or equivalent), university level calculus and physics. Homework assignments will require the use of Matlab and electronic submission of reports.

7800 Physiology Pro-Seminar (2)
Presentation of basic principles of physiology by staff and students.

7910 Practicum in Physiology (4) Prereq.: PHYSL 6000 and 6010 or equivalent.  Taught alternate years.  Required of majors; open to medical and graduate students.  A laboratory-oriented practicum emphasizing the practice of physiological technique as it pertains to specific research problems.  Course covers membrane models, ion selectivity, intracellular pH and Ca2+ regulation.  Recording surface potentials, ionic currents, nerve discharge and documentation of nervous activity with antibody markers are taught.  The second half of the practicum emphasizes assays involving antibodies including receptor binding, and radio immunoassays.  Microfluorometric analysis, confocal microscopy, in-vivo drug assay and genetic markers in disease are given practical consideration.

7920 Current Topics in Chemosensory Science (1-4) This course meets weekly to consider current topics in chemosensory sciences.  Students are expected to read current journal articles, prepare a written abstract and participate in discussions.

7930 Research in Physiology (1 to 14) Individual arrangements should be made prior to enrollment. Open to medical or graduate students by arrangement. Research on physiology of nervous, cardiovascular or respiratory system and on biophysics of cell membranes and membrane transport, as agreed to by student and faculty member.

7940 Faculty Rotation (1-4) Allow students to work in a faculty laboratory and learn new techniques.

7950 Professional Skills/Grant Writing (2) This course will provide a brief overview of professional skills for graduate students and postdoctoral fellows, and will focus on how to write grant proposals in the biomedical sciences.

7960 Physiology of Chemosensory Systems (2) Open to graduate and advanced undergraduate students. Topical discussion of a wide range of chemosensory systems including olfactory, gustatory, pheromonal and arterial chemoreceptors.

7970 Dissertation Research: Ph.D. (1 to 12)

7980 Faculty Consultation (3)

7990 Continuing Registration: Ph.D. (0) Continuing registration for Ph.D. students.