Markus Amann, PhD has been awarded a $1.2 million grant from Veteran’s Affairs for his project titled “Efficacy of exercise training in patients with HFpEF.”
Mar 24, 2020 12:00 AMThe project is set to start in October 2020 and commence in October 2024. The research in veterans with heart failure with preserved ejection fraction (HFpEF) will provide new information on the mechanisms determining the patients’ exercise intolerance and the efficacy of regular physical activity to improve this shortcoming by alleviating the patients’ neurocirculatory abnormalities. Specifically, we will focus on the role of nerves originating in working limb muscles in determining the patients’ exercise intolerance and compromised fatigue resistance before and after a chronic exercise intervention. By focusing on a specific mechanism, this project will evaluate the validity of exercise as an alternative treatment strategy with the overall purpose of improving the quality of life of veterans with HFpEF.