Publications

PubMed Listing for Erhu Cao (University of Utah)

The heteromeric PC-1/PC-2 polycystin complex is activated by the PC-1 N-terminus
Kotdaji Ha, Mai Nobuhara, Qinzhe Wang, Rebecca V Walker, Feng Qian, Christoph Schartner, Erhu Cao, Markus Delling
eLife. 2020; 9: e60684
Published online 2020 Nov 9
PMID: 33164752
 

Molecular dysregulation of ciliary polycystin-2 channels caused by variants in the TOP domain
Vien TN, Wang J, Ng LCT, Cao E, DeCaen P
Proc Natl Acad Sci U S A. 2020 Apr 24
PMID: 32332171

Structural Mechanisms of Transient Receptor Potential Ion Channels
Cao E.
J Gen Physiol 2020. 
PMID: 31972006

Structure of the human cation–chloride cotransporter NKCC1 determined by single-particle electron cryo-microscopy
Xiaoyong Yang, Qinzhe Wang & Erhu Cao
Nature Communications volume 11, Article number: 1016 (2020)
PMID: 32081947

Hydrophobic pore gates regulate ion permeation in polycystic kidney disease 2 and 2L1 channels
Wang Zheng, Xiaoyong Yang, Ruikun Hu, Ruiqi Cai, Laura Hofmann, Zhifei Wang, Qiaolin Hu, Xiong Liu, David Bulkey, Yong Yu, Jingfeng Tang , Veit Flockerzi, Ying Cao, Erhu Cao & Xing-Zhen Chen
Nature Communications. (2018) 9:2302.
PMID: 29899465

The Structure of the Polycystic Kidney Disease Channel PKD2 in Lipid Nanodiscs
Shen PS, Yang X, DeCaen PG, Liu X, Bulkley D, Clapham DE, Cao E
Cell. 2016 Oct 20;167(3):763-773.
PMID: 27768895

TRPV1 structures in nanodiscs reveal mechanisms of ligand and lipid action
Gao Y, Cao E, Julius D, Cheng Y
Nature. 2016 Jun 16;534(7607):347-51.
PMID: 27281200

Single particle electron cryo-microscopy of a mammalian ion channel
Liao M, Cao E, Julius D, Cheng Y.
Curr Opin Struct Biol. 2014 Aug;27:1-7.
Epub 2014 Mar 25. Review.
PMID: 24681231

TRPV1 structures in distinct conformations reveal activation mechanisms
Cao E, Liao M, Cheng Y, Julius D.
Nature. 2013 Dec 5;504(7478):113-8.
PMID: 24305161

Structure of the TRPV1 ion channel determined by electron cryo-microscopy 
Liao M, Cao E, Julius D, Cheng Y.
Nature. 2013 Dec 5;504(7478):107-12.
PMID: 24305160

TRPV1 channels are intrinsically heat sensitive and negatively regulated by phosphoinositide lipids
Cao E, Cordero-Morales JF, Liu B, Qin F, Julius D.
Neuron. 2013 Feb 20;77(4):667-79.
PubMed PMID:23439120; PubMed Central PMCID: PMC3583019.

Crystal structure of the complex between programmed death-1 (PD-1) and its ligand PD-L2
Lázár-Molnár E, Yan Q, Cao E, Ramagopal U, Nathenson SG, Almo SC.
Proc Natl Acad Sci U S A. 2008 Jul 29;105(30):10483-8. Epub 2008 Jul 18.
PubMed PMID: 18641123; PubMed Central PMCID: PMC2492495.

Structure of CD84 provides insight into SLAM family function
Yan Q, Malashkevich VN, Fedorov A, Fedorov E, Cao E, Lary JW, Cole JL, Nathenson SG, Almo SC.
Proc Natl Acad Sci U S A. 2007 Jun 19;104(25):10583-8. Epub 2007 Jun 11.
PubMed PMID: 17563375; PubMed Central PMCID: PMC1965556.

T cell immunoglobulin mucin-3 crystal structure reveals a galectin-9-independent ligand-binding surface
Cao E, Zang X, Ramagopal UA, Mukhopadhaya A, Fedorov A, Fedorov E, Zencheck WD, Lary JW, Cole JL, Deng H, Xiao H, Dilorenzo TP, Allison JP, Nathenson SG, Almo SC.
Immunity. 2007 Mar;26(3):311-21.
PubMed PMID: 17363302.

NTB-A receptor crystal structure: insights into homophilic interactions in the signaling lymphocytic activation molecule receptor family
Cao E, Ramagopal UA, Fedorov A, Fedorov E, Yan Q, Lary JW, Cole JL, Nathenson SG, Almo SC.
Immunity. 2006 Oct;25(4):559-70.
PubMed PMID: 17045824.

Gene cluster responsible for validamycin biosynthesis in Streptomyces hygroscopicus subsp. jinggangensis 5008 
Yu Y, Bai L, Minagawa K, Jian X, Li L, Li J, Chen S, Cao E, Mahmud T, Floss HG, Zhou X, Deng Z.
Appl Environ Microbiol. 2005 Sep;71(9):5066-76.
PubMed PMID: 16151088; PubMed Central PMCID: PMC1214664.

Structural and functional analysis of the costimulatory receptor programmed death-1
Zhang X, Schwartz JC, Guo X, Bhatia S, Cao E, Lorenz M, Cammer M, Chen L, Zhang ZY, Edidin MA, Nathenson SG, Almo SC.
Immunity. 2004 Mar;20(3):337-47. Erratum in: Immunity. 2004 May;20(5):651.
PubMed PMID: 15030777.