Publications

PubMed Listing since 2002 for Dana Carroll

Selected Publications (since 2002)

Yarrington, R.M., Verma, S., Schwartz, S., Trautman, J.K. and Carroll, D. (2018)
Nucleosomes inhibit target cleavage by CRISPR-Cas9 in vivo.
Proceedings of the National Academy of Sciences USA. doi/10.1073/pnas.1810062115

Urnov, F.D., Ronald, P.C. and Carroll, D. (2018)
A call for science-based review of the European court’s decision on gene-edited crops.
Nature Biotechnol. 36: 800-802. PMID: 3018854

Carroll, D.
Spotlight: p53 Throws CRISPR a Curve.
Trends Pharmacol. Sci. 39: 783-784. PMID: 30006230

Chandrasegaran, S., Bullen, C.K. and Carroll, D. (2017)
Genome editing of human embryos: To edit or not to edit, that is the question.
J. Clin. Invest. 127:3588-3590. PMCID: 5617656

Sarno, R., Vicq, Y., Uematsu, N., Luka, M., Lapierre, C., Carroll, D. Bastianelli, G., Serero, A. and Nicolas, A. (2017)
Programming sites of meiotic crossovers using Spo11 fusion proteins.
Nucleic Acids Res. 45: e164. PMID: 28977556

Carroll, D. (2017)
Genome editing: past, present and future.
Yale J. Biol. Med. 90: 653-659. PMCID: PMC5733845

DeWitt MA, Corn JE, Carroll D. (2017)
Genome editing via delivery of Cas9 ribonucleoprotein.
Methods. 2017 Apr 12. pii: S1046-2023(16)30297-3. doi:10.1016/j.ymeth.2017.04.003. [Epub ahead of print] PubMed PMID: 28410976.

Carroll D.
Genome editing: progress and challenges for medical applications.
Genome Med. 2016 Nov 15;8(1):120. PubMed PMID: 27846896; PubMed Central PMCID:PMC5111268.

DeWitt MA, Magis W, Bray NL, Wang T, Berman JR, Urbinati F, Heo SJ, Mitros T, Muñoz DP, Boffelli D, Kohn DB, Walters MC, Carroll D, Martin DI, Corn JE.
Selection-free genome editing of the sickle mutation in human adult hematopoietic stem/progenitor cells.
Sci Transl Med. 2016 Oct 12;8(360):360ra134. PubMed PMID: 27733558.

Carroll D, Van Eenennaam AL, Taylor JF, Seger J, Voytas DF.
Regulate genome-edited products, not genome editing itself.
Nat Biotechnol. 2016 May 6;34(5):477-9. doi: 10.1038/nbt.3566. PubMed PMID: 27153273.

Carroll D. (2016)
A Perspective on the State of Genome Editing.
Mol Ther. 2016 Mar;24(3):412-3. doi: 10.1038/mt.2016.28. PubMed PMID: 26952917; PubMed Central PMCID: PMC4786931.

Chandrasegaran S, Carroll D. (2015)
Origins of Programmable Nucleases for Genome Engineering.
J Mol Biol. 2016 Feb 27;428(5 Pt B):963-89. doi:10.1016/j.jmb.2015.10.014. Epub 2015 Oct 23. Review. PubMed PMID: 26506267;
PubMed Central PMCID: PMC4798875.

Carroll, D. (2016)
The CRISPR revolution: technical and societal aspects of current genome editing technologies.
Harvard Health Policy Review 15: 24-26.2016

Carroll, D. (2016)
The development and use of zinc-finger nucleases.
In Advances in Experimental Medicine and Biology, Vol. 895, Genome Editing: The Next Step in Gene Therapy,
T. Cathomen, M. Hirsch and M. H. Porteus, eds., Springer, New York, pp. 15-28. (2016) 

Carroll D, Charo RA. (2015) 
The societal opportunities and challenges of genome editing.
Genome Biol. 2015 Nov 5;16:242. doi: 10.1186/s13059-015-0812-0. PubMed PMID: 26537374; PubMed Central PMCID: PMC4634740.

Corrigan-Curay J, O'Reilly M, Kohn DB, Cannon PM, Bao G, Bushman FD, Carroll D, Cathomen T, Joung JK, Roth D, Sadelain M, Scharenberg AM, von Kalle C, Zhang F, Jambou R, Rosenthal E, Hassani M, Singh A, Porteus MH. (2015)
Genome editing technologies: defining a path to clinic.
Mol Ther. 2015 May;23(5):796-806. doi:10.1038/mt.2015.54. PubMed PMID: 25943494; PubMed Central PMCID: PMC4427885.

Bosley KS, Botchan M, Bredenoord AL, Carroll D, Charo RA, Charpentier E, Cohen R, Corn J, Doudna J, Feng G, Greely HT, Isasi R, Ji W, Kim JS, Knoppers B, Lanphier E, Li J, Lovell-Badge R, Martin GS, Moreno J, Naldini L, Pera M, Perry AC, Venter JC, Zhang F, Zhou Q. (2015)
CRISPR germline engineering--the community speaks.
Nat Biotechnol. 2015 May;33(5):478-86. doi: 10.1038/nbt.3227. PubMed PMID: 25965754.

Baltimore D, Berg P, Botchan M, Carroll D, Charo RA, Church G, Corn JE, Daley GQ, Doudna JA, Fenner M, Greely HT, Jinek M, Martin GS, Penhoet E, Puck J, Sternberg SH, Weissman JS, Yamamoto KR. (2015)
Biotechnology. A prudent path forward for genomic engineering and germline gene modification.
Science. 2015 Apr 3;348(6230):36-8. doi: 10.1126/science.aab1028. Epub 2015 Mar 19. PubMed PMID:25791083; PubMed Central PMCID: PMC4394183.

Hackett P, Carroll D. (2015)
Regulatory hurdles for agriculture GMOs.
Science. 2015 Mar 20;347(6228):1324. doi: 10.1126/science.347.6228.1324. PubMed PMID: 25792322.

Carroll D.
Genome editing by targeted chromosomal mutagenesis.
Methods Mol Biol. 2015;1239:1-13. doi: 10.1007/978-1-4939-1862-1_1. Review. PubMed PMID:25408398.

Carroll, D. 
Genome engineering with targetable nucleases.
In New DNA-Editing Approaches: Methods, Applications & Policy for Agriculture
NABC Report 26, A. Eaglesham and R.W.F. Hardy, eds., North American Agricultural Biotechnology Council, Ithaca, NY, pp. 25-28. (2015) 

Carroll D, Beumer KJ.
Genome engineering with TALENs and ZFNs: repair pathways and donor design.
Methods. 2014 Sep;69(2):137-41. doi:10.1016/j.ymeth.2014.03.026. Epub 2014 Apr 2. PubMed PMID: 24704173; PubMed Central PMCID: PMC4175112.

Beumer KJ, Carroll D.
Targeted genome engineering techniques in Drosophila.
Methods. 2014 Jun 15;68(1):29-37. doi: 10.1016/j.ymeth.2013.12.002. Epub 2014 Jan 8. Review. PubMed PMID: 24412316; PubMed Central PMCID: PMC4048800.

Carroll D.
Precision genome engineering.
Curr Biol. 2014 Feb 3;24(3):R102-3. doi: 10.1016/j.cub.2013.11.055. PubMed PMID: 24502778.

Carroll D.
Genome engineering with targetable nucleases.
Annu Rev Biochem. 2014;83:409-39. doi: 10.1146/annurev-biochem-060713-035418. Epub 2014 Mar 3. Review. PubMed PMID: 24606144.

Beumer KJ, Trautman JK, Christian M, Dahlem TJ, Lake CM, Hawley RS, Grunwald  DJ, Voytas DF, Carroll D.
Comparing zinc finger nucleases and transcription activator-like effector nucleases for gene targeting in Drosophila.
G3 (Bethesda). 2013 Oct 3;3(10):1717-25. doi: 10.1534/g3.113.007260. PubMed PMID:23979928; PubMed Central PMCID:PMC3789796.

Carroll D.
Staying on target with CRISPR-Cas. Nat Biotechnol.
2013 Sep;31(9):807-9. doi: 10.1038/nbt.2684. PubMed PMID: 24022156.

Carroll, D. 
Site-directed insertion of transgenes in
Drosophila.
In
Topics in Current Genetics, vol., 23, Site-directed insertion of transgenes, S. Renault and P. Duchateau, eds., Springer, pp. 317-326. (2012) 

Beumer KJ, Trautman JK, Mukherjee K, Carroll D.
Donor DNA Utilization During Gene Targeting with Zinc-Finger Nucleases.
G3 (Bethesda). 2013 Apr 9;3(4):657-664. doi: 10.1534/g3.112.005439. PubMed PMID: 23550125; PubMed Central PMCID:PMC3618352.

Carroll D.
A CRISPR approach to gene targeting.
Mol Ther. 2012 Sep;20(9):1658-60. doi: 10.1038/mt.2012.171. PubMed PMID: 22945229; PubMed Central PMCID: PMC3437577.

Carroll D.
Genome engineering with zinc-finger nucleases.
Genetics. 2011 Aug;188(4):773-82. doi: 10.1534/genetics.111.131433. Review. PubMed PMID: 21828278; PubMed Central PMCID:PMC3176093.

Carroll D.
Zinc-finger nucleases: a panoramic view.
Curr Gene Ther. 2011 Feb;11(1):2-10. Review. PubMed PMID: 21182468.

Carroll D, Beumer KJ, Trautman JK.
High-efficiency gene targeting in Drosophila with zinc finger nucleases.
Methods Mol Biol. 2010;649:271-80. doi:10.1007/978-1-60761-753-2_17. PubMed PMID: 20680841.

Bozas A, Beumer KJ, Trautman JK, Carroll D.
Genetic analysis of zinc-finger nuclease-induced gene targeting in Drosophila.
Genetics. 2009 Jul;182(3):641-51. doi: 10.1534/genetics.109.101329. Epub 2009 Apr 20. PubMed PMID: 19380480; PubMedCentral  PMCID: PMC2710147.

Beumer KJ, Trautman JK, Bozas A, Liu JL, Rutter J, Gall JG, Carroll D.
Efficient gene targeting in Drosophila by direct embryo injection with
zinc-finger nucleases.
Proc Natl Acad Sci U S A. 2008 Dec 16;105(50):19821-6. doi: 10.1073/pnas.0810475105. Epub 2008 Dec 8. PubMed PMID: 19064913;PubMed Central PMCID: PMC2604940.

Davis MW, Morton JJ, Carroll D, Jorgensen EM.
Gene activation using FLP recombinase in C. elegans.
PLoS Genet. 2008 Mar 21;4(3):e1000028. doi:10.1371/journal.pgen.1000028. PubMed PMID: 18369447; PubMed Central PMCID:PMC2265415.

Carroll D, Beumer KJ, Morton JJ, Bozas A, Trautman JK.
Gene targeting in Drosophila and Caenorhabditis elegans with zinc-finger nucleases.
Methods Mol Biol. 2008;435:63-77. doi: 10.1007/978-1-59745-232-8_5. PubMed PMID: 18370068.

Morton J, Davis MW, Jorgensen EM, Carroll D.
Induction and repair of zinc-finger nuclease-targeted double-strand breaks in Caenorhabditis elegans somatic cells.
Proc Natl Acad Sci U S A. 2006 Oct 31;103(44):16370-5. Epub 2006 Oct 23. PubMed PMID: 17060623; PubMed Central PMCID:PMC1637589.

Beumer K, Bhattacharyya G, Bibikova M, Trautman JK, Carroll D.
Efficient gene targeting in Drosophila with zinc-finger nucleases.
Genetics. 2006 Apr;172(4):2391-403. Epub 2006 Feb 1. PubMed PMID: 16452139; PubMed Central PMCID: PMC1456366.

Carroll D, Morton JJ, Beumer KJ, Segal DJ.
Design, construction and in vitro testing of zinc finger nucleases.
Nat Protoc. 2006;1(3):1329-41. PubMed PMID:17406419.

Lloyd A, Plaisier CL, Carroll D, Drews GN.
Targeted mutagenesis using zinc-finger nucleases in Arabidopsis.
Proc Natl Acad Sci U S A. 2005 Feb 8;102(6):2232-7. Epub 2005 Jan 26. PubMed PMID: 15677315; PubMed Central PMCID:PMC548540.

Carroll D.
Using nucleases to stimulate homologous recombination.
Methods Mol Biol. 2004;262:195-207. Review. PubMed PMID: 14769963.

Bibikova M, Beumer K, Trautman JK, Carroll D.
Enhancing gene targeting with designed zinc finger nucleases.
Science. 2003 May 2;300(5620):764. PubMed PMID:12730594.

Bibikova M, Golic M, Golic KG, Carroll D.
Targeted chromosomal cleavage and mutagenesis in Drosophila using zinc-finger nucleases.
Genetics. 2002 Jul;161(3):1169-75. PubMed PMID: 12136019; PubMed Central PMCID: PMC1462166.


 

Interview with Dana Carroll