Featured Publications

Monroe N, Han H, Shen PS, Sundquist WI, Hill CP. (2017)
eLife, e24487. doi: 10.7554/eLife.24487 [Epub ahead of print]
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Designed proteins induce the formation of nanocage-containing extracellular vesicles

Votteler J, Ogohara C, Yi S, Hsia Y, Nattermann U, Belnap DM, King NP, Sundquist WI (2016)
Nature, 540(7632):292-295

 Isosurface model of a vesicle filled with nanocages (left) and a cryo-EM reconstruction of a nanocage with the computational design model (green ribbon) fitted into (right)

Structure and Membrane Remodeling Activity of ESCRT-III Helical Polymers.

McCullough J, Clippinger AK, Talledge N, Skowyra ML, Saunders MG, Naismith TV, Colf LA, Afonine P, Arthur C, Sundquist WI, Hanson PI, Frost A. (2015)
Science, 350(6267), 1548-51 
 Figure 1 CHMP1B opening, strand structure, and electrostatic surface potentials of the IST1NTD-CHMP1B assembly

CELL BIOLOGY. An ESCRT to Seal the Envelope.
Sundquist WI, Ullman KS. (2015)
Science, 348(6241), 1314-5
Fig.1 Seeking closure

Vps2p helix 5 peptides bind the Vps4p ATPase cassette

The Oligomeric State of the Active Vps4 AAA ATPase.
Monroe N, Han H, Gonciarz MD, Eckert DM, Karren MA, Whitby FG, Sundquist WI, Hill CP. (2014) 
J Mol Biol., 426(3), 510-25
Crystal structures of the ATPase cassettes of SsoVps4 and AhosVps4.

ESCRT Requirements for EIAV Budding.
Sandrin V, Sundquist WI.(2013)
Retrovirology, 10(104), 1742-4690
Summary of ESCRT proteins and interactions that contribute to EIAV budding.

HIV-1 Assembly, Budding, and Maturation.
Sundquist WI, Kräusslich HG. (2012)
Review. Erratum in: Cold Spring Harb Perspect Med, 2(7), a015420.

Assembly and structure of immature HIV-1 particles.

How to Assemble a Capsid.
Sundquist WI, Hill CP. (2007)
Cell, 131(1), 17-9
Hexagonal Lattice of the HIV-1 CA Protein

Ubiquitin recognition by the human TSG101 protein.
Sundquist WI, Schubert HL, Kelly BN, Hill GC, Holton JM, Hill CP. (2008)
Mol Cell., 13(6),783-9

UEV Can Bind Ub and PTAP Peptides Independently

HIV Gag Mimics the Tsg101-Recruiting Activity of the Human Hrs Protein.
Pornillos O, Higginson DS, Stray KM, Fisher RD, Garrus JE, Payne M, He GP, Wang HE, Morham SG, Sundquist WI. (2003J Cell Biol., 162(3), 425-34.
Electron microscopic analyses of Gag–GFP and Gag–Hrs budding.
For more publicatons by the Sundquist Laboratory, see PubMed Listings for Wes Sundquist