U-CARS 2018

On January  11 - 12, 2018, attendees from around the world gathered once again at the 6th Annual Utah Cardiac Recovery Symposium (U-CARS).  The two day symposium was held at the University of Utah School of Medicine Eccles Health Science Education Building in scenic Salt Lake City, Utah.

Thursday, January 11th's keynote address was delivered by Milton Packer, MD,  DistinguishedScholar in Cardiovascular Science, Baylor University Medical Center.  Friday, January 12th's keynote address was delivered by Patrick T. O'Gara, MD, Director of Strategic Planning, Division of Cardiovascular Medicine, Brigham and Women's, Professor, Harvard Medical School.

The 2018 symposium attracted over 530 attendees, sparked in-depth discussions and featured ground-breaking research from around the globe in the field of cardiac recovery.
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Dr. Stavros Drakos talks about highlights of the 2018 U-CARS


Thursday, January 11, 2018

9:00 - 9:15am
Opening Remarks

9:15 - 10:15am
Session 1: What is Cardiac Recovery?
Chairpersons: James Fang, MD,
U of Utah, Salt Lake City and Donald Lappe, MD, Intermountain Medical Center, Salt Lake City



1. Focus on the myocardium

Jane E. Wilcox, MD, MSc, Northwestern University, Feinberg School of Medicine

2. Understanding recovery through circulating biomarkers.

Gary Michael Felker, MD, Duke University, Durham, NC

10:15 - 11:00am
HF-recovered-EF: What Does It Mean?
Milton Packer, MD,
Distinguished Scholar in Cardiovascular Science 
Baylor University Medical Center

11:00 - 12:30pm Lunch - Moderated Poster Session
Poster discussants: A.G Kfoury, MD, Intermountain Medical Center - Rashmee Shah, MD U of Utah - Dipayan Chaudhuri, MD U of Utah

12:30 - 2:15pm
Session 2: Myocardial Recovery Innovation 
Chairpersons: Kirk Knowlton, MD Intermountain Medical Center, Salt Lake City - Jared Rutter, PhD, U of Utah, Salt Lake City



1.What can we learn from recovering the donor heart.

Ulrich P. Jorde, MD, Montefiore/Albert Einstein

2. Regenerative medicine driving myocardial recovery: bench to bedside

Hesham Sadek, MDPhD UT Southwestern, Dallas, TX

3. Adult heart failure: a developmental genetics perspective

Joseph Yost, PhD, U of Utah, Salt Lake City, UT

4. Future directions from cardiovascular genetics.

Martin Tristani-Firouzi, MD, U of Utah/ Primary Children’s/CVRTI, Salt Lake City, UT

5. Discoveries from the cardiac metabolism front: therapeutic implications. 

Konstantinos Drosatos, PhD, Temple University, Philadelphia

2:15 - 2:45pm   BREAK

2:45 - 5:30pm
Session 3: How Can HFpEF Inform Us About Myocardial Recovery And Vice Versa.
Chairpersons: Nancy K. Sweitzer, MD U of Arizona, Tucson John Ryan, MD, U of Utah, Salt Lake City

Session's central theme: 
HFpEF and HFrEF: distinct phenotypes or continuum?



1. Invasive cardiopulmonary exercise testing to predict outcomes.

Aaron Waxman, MD, PhD Brigham and Women's Hospital, Boston, MA

2.Understanding the role of periphery.

Russell S. Richardson, PhD, U of Utah & VA Medical Center, Salt Lake City, UT

3. Understanding the role of the pulmonary circulation.

Vojtech Melenovsky, MD, IKEM, Prague, Czech Republic

4. Leveraging the strengths of advanced imaging to provide precision care.

Amit Patel, MD, U of Chicago Chicago, IL

5. Back to the animal models? 

Flora Sam, MD, Boston University, Boston, MA

6. Time to abandon ejection fraction and other new ideas. 

Mathew Maurer, MD, Columbia University, Chicago, IL

Focused Panel discussion (chairs & speakers): “Are Systolic and Diastolic Heart Failure Overlapping or Distinct Phenotypes Within the Heart Failure Spectrum”

7:00 - 9:30 pm
Symposium Dinner

Friday, January 12, 2018

7:00 - 8:15am
Session 4: Oral Presentation of Best Abstracts
Chairpersons: Stavros G. Drakos, MD, PhD, U of Utah, Salt Lake City, UT and M. Elizabeth Hale Hammond, MD, U of Utah, Salt Lake City, UT

8:15 - 9:00am
Keynote address: 
Predictors of Post-operative LV Function Following Heart Valve Surgery. What Are We Missing?

Patrick T. O'Gara, MD
Director of Strategic Planning
Professor, Harvard Medical School,
Division of CV Medicine, BWH

9:00 - 11:30am
Session 5: Mechanically Assisted Circulation and Cardiac Recovery
Chairpersons: Ulrich Jorde, MD, Montefiore/ Albert Einstein & Stephen McKellar, MD, U of Utah, Salt Lake City, UT 



1. RESTAGE-HF, a North American Bridge to Recovery Trial: Preliminary Results

Brian Lowes, MD, PhD, U of Nebraska, Omaha, NB

2. Vancouver Recovery Program

Anson Cheung, MD, British Columbia, Vancouver, Canada

3. Toronto Recovery Program.

Phyllis Billia, MD, PhD, U of Toronto, Canada

4. Post-VAD explantation long-term cardiac and exercise capacity.

Emma Birks, MD, U of Louisville, Louisville, KY

5. How to build pumps to promote recovery.

Trevor Snyder, PhD, Institute for Biomedical Engineering, Science and Technology, U of Oklahoma

6. Utah Cardiac Recovery Program: what have we learned? 

Stavros G. Drakos, MD, PhD, U of Utah, Salt Lake City, UT

Focused Panel discussion (chairs & speakers): “MCS and Recovery: Where Do We Go From Here”

11:30 - 12:30pm Lunch - Poster Viewing

12:30am - 1:30pm
"How to…" practical break-out sessions:

A. Discussion Leaders - Emma Birks, MD, PhD (U Louisville) & Omar Wever-Pinzon, MD: i) How to treat patients during LVAD support, ii) How to serially screen for cardiac recovery iii) Weaning criteria. INTERACTIVE CASES (HSEB Alumni Hall)
B. Discussion Leader - Nir Uriel, MD (U Chicago): How to stop the VAD: surgical and percutaneous approaches – INTERACTIVE CASES (HSEB 1730)
C. Discussion Leaders – Jennifer L. Cook, MD (U of Arizona) & Josef Stehlik, MD: Patient-centered decision-making: provider and patient perspectives – PATIENTS LIVE PARTICIPATION (HSEB 2958)

1:30 - 2:30 PM - Plenary Discussion – Chairpersons: Craig Selzman, MD U of Utah, Salt Lake City, UT A.G Kfoury, MD, Intermountain Medical Center, Salt Lake City, UT:
Discussion leaders to present ‘take home’ messages from the 3 break-out sessions

2:30 - 3:00pm  BREAK

3:00 - 5:30pm
Session 6: Cardiogenic Shock and Recovery
Chairpersons: Francisco Arabia, MD, Cedars Sinai Medical Center, Los Angeles, CA & Theophilus Owan, MD U of Utah, Salt Lake City, UT  



1.How to improve outcomes: the role of myocardium and periphery. E. Magnus Ohman, MD Duke University, Durham, NC
2. The U of Utah ‘Shock Team’ Approach and Basic Algorithm - interactive clinical cases.

Jose Nativi-Nicolau MD, U of Utah, Salt Lake City, UT

3. INTERMACS 0: How to select patients and mechanical support strategies - interactive clinical cases. Susan M. Joseph, MD, Baylor University Medical Center, Dallas, TX 

Chairpersons: Anwar Tandar, MD University of Utah, Salt Lake City, UT – Joseph Tonna, MD U of Utah, Salt Lake City, UT 
Cardiogenic shock therapies: Surgical (Simon Maltais, MD, PhD, Mayo Clinic, Rochester, MN) Versus Percutaneous approach (Nir Uriel, MD, U Chicago, Chicago, IL)


Closing Remarks