U-CARS 2020

On January 16-17, 2020, esteemed speakers from around the world gathered for the 8th Annual Utah Cardiac Recovery Symposium (U-CARS).  The two day symposium was held at the University of Utah Cleone Peterson Eccles Alumni House in scenic Salt Lake City, Utah.

Thursday, January 16th's keynote address was delivered by Douglas L. Mann, MD, Medical Director and Cardiologist-in-Chief of the Heart and Vascular Center, Barnes-Jewish Hospital.  Friday, January 17th's keynote address was delivered by M. Elizabeth Hale Hammond, MD, Chairman of the Department of Pathology, LDS Hospital and Urban Central Region, from Intermountain Health Care.

The 2020 symposium hosted over 500 attendees once again and featured ground-breaking research in the field of cardiac recovery spanning clinical, translational and basic sciences.

Couldn't attend in person or just want to see the 2020 sessions again? 

View via the on demand link here

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Thursday, January 16, 2020


8:00AM Registration & Check-in

8:00 - 8:45AM

Keynote Address

Douglas Mann, MD- Washington University School of Medicine, St. Louis

"Myocardial Remission: End of the Beginning or Beginning of the End?"

Introduction by Edward M. Gilbert, MD - U of U Health

8:45 - 10:30AM

UCAR Collaborations: Outline of Strategy for Clinical and Translational Innovation.

Stavros Drakos, MD, PhD - U of U Health

UCAR and Collaborators: (A) Clinical Innovation

Chairs: James Fang - U of Utah Health and Kirk Knowlton, MD -Intermountain Healthcare

UTAH-INOVA Reverse Remodeling Stages.

Palak Shah, MD, Inova

Non-invasive Pressure Volume Loops to Monitor and Diagnose Cardiac Recovery.

Christopher Hayward, MD - Sydney, Australia

What Happens Long-Term After We Wean a Cardiac Assist Device in Chronic Heart Failure Patients?

Snehal Patel, MD - Montefiore/Albert Einstein 

How to Start a Cardiac RecoveryProgram: the Example of Allegheny.

Manreet Kanwar, MD - Allegheny

10:30-11:00 AM Break

11:00AM - 12:30PM

UCAR and Collaborators: (B) Translational Innovation

Chairs: Robin Shaw, MD, PhD - U of U Health and Joseph Yost, PhD - U of U Health

Long Non-Coding RNAs and Myocardial Recovery Mechanisms. Saumya Das, MD - MGH/Harvard

Innate Immunity, Macrophage Heterogeneity and Myocardial Recovery.

Kory Lavine, MD, PhD -Wash U

Regeneration in the Human Heart.

Olaf Bergman, PhD -Karolinska, Sweden

12:30 - 1:30PM

Lunch - Moderated Posters Session (Non-CME)

Commitee Chair: T. Jared Bunch, MD - U of U Health

Committee Members: Mark Ibrahim, MD -U of U Health; Sihem Boudina, PhD, U of U Health; Virginia Hebl, MD -Intermountain Healthcare; Viet Le, PA-C-Intermountain Healthcare; Jose Nativi-Nicolau, MD - U of U Health; Benjamin Steinberg, MD - U of U Health and Eric Tuday, MD, PhD - U of U Health

The committee will grade the posters and the top 3 will receive an award.1:30 - 3:00PM

Innovation in Myocardial Recovery: Bench to Bedside

Chairs: Jared Rutter, PhD - HHMI/ U of U Health and Scott Summers, PhD - U of U Health

Mitochondria and Myocardial Recovery: Lessons From Disease Models.

Dipayan Chaudhuri, MD/PhD - U of U Health

The Role of Metabolism in Cardiac Repair.

Filio Billia, MD/PhD - U of Toronto

Role of the Acute Sterile Immune Response in Cardiac Rejuvenation by Cell Therapy.

Jeff Molkentin, PhD - HHMI/U of Cincinnati

3:00 - 3:15PMBreak3:15 - 4:45PM

Innovation in Myocardial Recovery and MCS

Chairs: Boudi Kfoury, MD - Intermountain Healthcare and Antonio Cabrera, MD, Primary Children’s/U of U Health

Do We Effectively Unload the Heart During Chronic Mechanical Circulatory Support? Should We?

Nir Uriel, MD - Columbia

Exercise Physiology During Mechanical Circulatory Support: Implications for Myocardial Recovery.

Finn Gustafsson, MD - U of Copenhagen, Denmark

What is a Sufficient Degree of Cardiac Improvement During LVAD to Lead to Favorable Long-Term Outcomes After Device Weaning?

Evgenij Potapov, MD - Berlin Heart Institute, Germany

What are We Learning From Pediatric Cardiac Recovery Programs?

Melanie Everitt, MD - U of Colorado

4:45 - 6:00PM

“How To” – Focused Practical Discussions

  1. A)   i) How to Treat Patients During LVAD Support
  2. ii) How to Serially Screen for Cardiac Recovery

iii) Weaning Criteria – INTERACTIVE CASES

DISCUSSION LEADERS: Melana Yuzefpolskaya, MD - Columbia; Iki Adachi, MD - Texas Children’s/Baylor & Omar Wever Pinzon, MD - U of U Health (25 min)

B)   Myocardial Recovery: Ventricular Assist Device Explantation versus Decommissioning – INTERACTIVE CASES

DISCUSSION LEADERS: Ivan Netuka, MD, PhD - Prague & Craig Selzman, MD - U of U Health (25min)

  1. C) Patient-centered decision making and PRO in patients with “Recovered-EF”-

    Interactive Participation of Patients and Clinicians

DISCUSSION LEADERS: Kathleen Grady, PhD, RN, MS, FAAN - Northwestern University & Josef Stehlik, MD- U of U Health (25min)

Agenda - Friday, January 17, 2020


7:30 - 8:00AM Registration Check-in

8:00 - 9:30AM Featured oral presentations of selected abstracts (Non-CME)

Chairs: Sarah Franklin, PhD - U of U Health; Anna Catino, MD - U of U Health and Rashmee Shah, MD - U of U Health


Keynote Address

Elizabeth Hammond, MD - Intermountain Healthcare & University of Utah School of Medicine

"The Impact of Dogmas in Medicine: The Case of Antibody-Mediated Rejection"

Introduction by A. G. Kfoury, MD - Intermountain Healthcare

10:15 - 10:30AM


10:30AM - 12:00PM

Invited Theme: Cardiorenal, End Organs, Systemic Milieu and Myocardial Recovery

Chairs: Aylin Rodan, MD/PhD - U of U Health and Kevin Shah, MD - U of U Health

Innovation in the Pathophysiology of Cardiorenal Syndrome. Jeff Testani, MD - Yale University

What Happens to the Brain-CV-Renal Axis When the Circulation is Mechanically Supported?

William Cornwell, MD - U of Colorado

Should We Focus on the Gut/Microbiota and the Kidney to Recover the Heart?

Wilson Tang, MD - Cleveland Clinic

12:00 - 1:00PM

Lunch - Poster Viewing Session

1:00 - 2:00PM

The Myocardial Recovery Field in the Midst of a Percutaneous Revolution in Valve Therapy.

Chairs: Fred Welt, MD - U of U Health and Brent Wilson, MD/PhD - U of U Health

  • Aortic Stenosis-Induced Heart Failure and TAVR. Where is the Point of No Return for Myocardial Recovery and Where for Patient Recovery?

    Anwar Tandar, MD - U of U Health

    What is the Impact of Repairing the Mitral Valve on Myocardial Function and Structure?

    Brian Whisenant, MD - Intermountain Healthcare 
  • How to Make Sense of the Conflicting Results in Mitral Valve Interventions: Proportionate and Disproportionate Mitral Regurgitation.

    Jerry Estep, MD - Cleveland Clinic 

Panel discussion (15 min) chairs and speakers

2:00 - 2:15PM


2:15 - 3:45PM

Myocardial and Patient Recovery from Cardiogenic Shock: Unmet Needs Record-Field – Part A

(all talks will include an interactive case presentation)

Chairs: Joseph Tonna, MD - U of U Health & Evgenij Potapov, MD, Berlin Heart Institute 

Do We Need Invasive Hemodynamics/Swan-Ganz Catheter in the Management of Cardiogenic Shock?

Joann Lindenfeld, MD - Vanderbilt

Cardiogenic Shock Requiring MCS: Catheter-based Assist Devices? VA-ECMO? Combination?

Simon Maybaum, MD -Hofstra School of Medicine/Northwell Health

SHOCK TEAM: Institutional Cultural Change, Efficiency, Effectiveness & Other Challenges.

Stavros Drakos, MD/PhD - U of U Health

3:45 - 5:30PM

Myocardial and Patient Recovery from Cardiogenic Shock: Unmet Needs Record-Field – Part B

Chairs: Ivan Netuka, MD, PhD - Prague, Czech Republic & Nir Uriel, MD - Columbia

Shock Severity SCAI Classification: How to “Identify, Communicate and Predict” in the Middle of the Shock Hurricane.

David Baran, MD - Sentara

Identifying Clinical and Biological Turning Points to Justify Early Short-term MCS.

Stephen McKellar, MD - U of U Health

ECMO-CPR: Where is the Point of No Return?

Demetri Yannopoulos, MD - U of Minnesota

Featured Presentation - Putting Parts A & B Together: How to Advance the Shock Field Through Registries, RCTs and Other Ideas.

Sean Van Diepen, MD - U of Alberta, Canada