History of the Unit
In 2007 the University of Utah GCRC community of scientists and visionaries successfully competed for a new clinical research award, a Clinical and Translational Science Award. The clinical research enterprise was re-envisioned, the expanded model now accelerates the full cycle of translation from bench-to-bedside, to the community, and back to the bench. This modern model of the Clinical Services Core successfully supports: interdisciplinary teams and infrastructure, new technology, training clinical scientists, shared resources and community outreach.
Clinical Services at the University of Utah, a 14 room nursing and administrative unit, is housed in 5200 square feet of prime clinical space on the fifth floor of the University of Utah Hospital. Our CSC serves as the Utah CCTS laboratory for performance of first-in-human clinical investigations. In addition to bed space and nursing, integral resources include a research pharmacy, kitchen with nutritionist support, endoscopy, electrodiagnostic and body composition suites, and clinical laboratory facilities.
Active protocols and study visits represent NIH funded studies, investigator-initiated studies, pilot studies, and industry-sponsored trials. From 2007-2012 our active protocols increased from 69 to 120 and subject visits increased from 2200 to 3800 annually for 7800 visit hours. Half of our visits represent NIH funded studies, and use of the Utah CSC saved an estimated $720,000 for parent NIH institutes.
Current CSC utilization builds on the historic strengths of the CCTS in phenotype/genotype correlation, cancer genetics, and pediatric disease. Diversity of investigators using the CSC continues to increase; pediatric protocols now account for 28 percent of CSC nursing hours. The CSC actively recruits clinical investigators and protocols from all clinical specialties, nursing, pharmacy, exercise physiology, and physical therapy.
The CSC Internal Advisory Committee (IAC) reviews new applications based on an NIH review panel model to insure scientific quality and significance, impact to the CCTS, research subject safety, and adherence to regulatory requirements. Investigators from diverse academic communities serve on the internal advisory committee. Clinical care standards for patient safety and quality align with University of Utah Health institutional requirements for dual Joint Commission and DNV accreditation in 2013.