Carroll, Dana , PhD

Research Interests

  • Genome Engineering
  • DNA Repair
  • CRISPRs
  • TALENs
  • Zinc-Finger Nucleases

Labs

Lab Website

Languages

  • English

Academic Information

  • Departments: Biochemistry - Distinguished Professor
  • Cancer Center Programs: Nuclear Control of Cell Growth & Differentiation

Academic Office Information

  • 801-581-5977
  • Emma Eccles Jones Research Building
    Biochemistry
    15 North Medical Drive East, Room: 4520B
    Salt Lake City, UT 84112

Academic Bio

Dana Carroll, PhD, is a Distinguished Professor in the Department of Biochemistry at the University of Utah School of Medicine and a member of the Nuclear Control of Cell Growth and Differentiation Program at the Huntsman Cancer Institute.

Carroll’s research involves genome engineering using targetable nucleases. His lab pioneered the development of zinc-finger nucleases as gene targeting tools and continued working with the more recent TALENs and CRISPR/Cas nucleases. Much of the effort was focused on optimizing the efficiency of these reagents for targeted mutagenesis and gene replacement, which could ultimately provide treatment for many diseases, including certain types of cancer. This technology has now been applied to more than 200 different organisms, including current clinical trials in humans and improvements in crop plants and livestock. Carroll's current interests include societal implications of genome editing.

Carroll received his bachelor’s degree from Swarthmore College, Pennsylvania, and his PhD from the University of California, Berkeley. He did postdoctoral research at the Beatson Institute for Cancer Research in Glasgow, Scotland, and at the Carnegie Institution Department of Embryology in Baltimore.

Education History

Type School Degree
Postdoctoral Fellowship Carnegie Institution of Washington
Department of Embryology, advisor: Donald D. Brown
Postdoctoral Fellow
Postdoctoral Fellowship Beatson Institute for Cancer Research
advisor: John Paul
Postdoctoral Fellow
Doctoral Training University of California, Berkeley
Department of Chemistry, thesis advisor: Ignacio Tinoco, Jr.
Ph.D.
Undergraduate Swarthmore College
Chemistry
B.A.

Global Impact

Education History

Type School Degree Country
Postdoctoral Fellowship Beatson Institute for Cancer Research
advisor: John Paul
Postdoctoral Fellow United Kingdom

Selected Publications

Journal Article

  1. Carroll D (2018 Sep). p53 Throws CRISPR a Curve. Trends Pharmacol Sci, 39(9), 783-784.
  2. Urnov FD, Ronald PC, Carroll D (2018 Sep 6). A call for science-based review of the European court's decision on gene-edited crops. Nat Biotechnol, 36(9), 800-802.
  3. Yarrington RM, Verma S, Schwartz S, Trautman JK, Carroll D (2018 Sep 10). Nucleosomes inhibit target cleavage by CRISPR-Cas9 in vivo.LID - 201810062 [pii]LID - 10.1073/pnas.1810062115 [doi]. (Epub ahead of print) Proc Natl Acad Sci U S A.
  4. DeWitt MA, Corn JE, Carroll D (2017 May 15). Genome editing via delivery of Cas9 ribonucleoprotein. Methods, 121-122, 9-15.
  5. Chandrasegaran S, Bullen CK, Carroll D (2017 Oct 2). Genome editing of human embryos: to edit or not to edit, that is the question. J Clin Invest, 127(10), 3588-3590.
  6. Sarno R, Vicq Y, Uematsu N, Luka M, Lapierre C, Carroll D, Bastianelli G, Serero A, Nicolas A (2017 Nov 2). Programming sites of meiotic crossovers using Spo11 fusion proteins. Nucleic Acids Res, 45(19), e164.
  7. Carroll D, Van Eenennaam AL, Taylor JF, Seger J, Voytas DF (2016 May 6). Regulate genome-edited products, not genome editing itself. Nat Biotechnol, 34(5), 477-9.
  8. DeWitt MA, Magis W, Bray NL, Wang T, Berman JR, Urbinati F, Heo SJ, Mitros T, Munoz DP, Boffelli D, Kohn DB, Walters MC, Carroll D, Martin DI, Corn JE (2016 Oct 12). Selection-free genome editing of the sickle mutation in human adult hematopoietic stem/progenitor cells. Sci Transl Med, 8(360), 360ra134.
  9. Carroll D (2016 Nov 15). Genome editing: progress and challenges for medical applications. Genome Medicine, 8(1), 120.
  10. Carroll D (2016 Mar). A Perspective on the State of Genome Editing. Mol Ther, 24(3), 412-3.
  11. Baltimore D, Berg P, Botchan M, Carroll D, Charo RA, Church G, Corn JE, Daley GQ, Doudna JA, Fenner M, Greely HT, Jinek M, Martin GS, Penhoet E, Puck J, Sternberg SH, Weissman JS, Yamamoto KR (2015 Apr 3). Biotechnology. A prudent path forward for genomic engineering and germline gene modification. Science, 348(6230), 36-8.
  12. Bosley KS, Botchan M, Bredenoord AL, Carroll D, Charo RA, Charpentier E, Cohen R, Corn J, Doudna J, Feng G, Greely HT, Isasi R, Ji W, Kim JS, Knoppers B, Lanphier E, Li J, Lovell-Badge R, Martin GS, Moreno J, Naldini L, Pera M, Perry AC, Venter JC, Zhang F, Zhou Q (2015 May). CRISPR germline engineering--the community speaks. Nat Biotechnol, 33(5), 478-86.
  13. Carroll D, Charo RA (2015). The societal opportunities and challenges of genome editing. Genome Biology, 16(1), 242.
  14. Carroll D (2014 Feb 3). Precision genome engineering. Curr Biol, 24(3), R102-3.
  15. Carroll D, Beumer KJ (2014 Sep). Genome engineering with TALENs and ZFNs: repair pathways and donor design. Methods, 69(2), 137-41.
  16. Cho SW, Lee J, Carroll D, Kim JS, Lee J (2013 Nov). Heritable gene knockout in Caenorhabditis elegans by direct injection of Cas9-sgRNA ribonucleoproteins. Genetics, 195(3), 1177-80.
  17. Beumer KJ, Trautman JK, Christian M, Dahlem TJ, Lake CM, Hawley RS, Grunwald DJ, Voytas DF, Carroll D (2013 Oct). Comparing zinc finger nucleases and transcription activator-like effector nucleases for gene targeting in Drosophila. G3 (Bethesda), 3(10), 1717-25.
  18. Carroll D (2013 Sep). Staying on target with CRISPR-Cas. Nat Biotechnol, 31(9), 807-9.
  19. Beumer KJ, Trautman JK, Mukherjee K, Carroll D (2013 Mar 22). Donor DNA Utilization during Gene Targeting with Zinc-finger Nucleases.LID - g3.112.005439v2 [pii]LID - 10.1534/g3.112.005439 [doi]. (Epub ahead of print) G3 (Bethesda).
  20. Takasu Y, Kobayashi I, Beumer K, Uchino K, Sezutsu H, Sajwan S, Carroll D, Tamura T, Zurovec M (). Targeted mutagenesis in the silkworm Bombyx mori using zinc finger nuclease mRNA injection. Insect Biochem Mol Biol, 40(10), 759-65.
  21. Kim JS, Lee HJ, Carroll D (2010 Feb). Genome editing with modularly assembled zinc-finger nucleases. Nat Methods, 7(2), 91; author reply 91-2.
  22. Bozas A, Beumer KJ, Trautman JK, Carroll D (2009 Jul). Genetic analysis of zinc-finger nuclease-induced gene targeting in Drosophila. Genetics, 182(3), 641-51.
  23. Mittelman D, Moye C, Morton J, Sykoudis K, Lin Y, Carroll D, Wilson JH (2009 Jun 16). Zinc-finger directed double-strand breaks within CAG repeat tracts promote repeat instability in human cells. Proc Natl Acad Sci U S A, 106(24), 9607-12.
  24. Liu JL, Wu Z, Nizami Z, Deryusheva S, Rajendra TK, Beumer KJ, Gao H, Matera AG, Carroll D, Gall JG (2009 Mar). Coilin is essential for Cajal body organization in Drosophila melanogaster. Mol Biol Cell, 20(6), 1661-70.
  25. Davis MW, Morton JJ, Carroll D, Jorgensen EM (2008 Mar). Gene activation using FLP recombinase in C. elegans. PLoS Genet, 4(3), e1000028.
  26. Beumer KJ, Trautman JK, Bozas A, Liu JL, Rutter J, Gall JG, Carroll D (2008 Dec 16). Efficient gene targeting in Drosophila by direct embryo injection with zinc-finger nucleases. Proc Natl Acad Sci U S A, 105(50), 19821-6.
  27. Beumer K, Bhattacharyya G, Bibikova M, Trautman JK, Carroll D (2006 Apr). Efficient gene targeting in Drosophila with zinc-finger nucleases. Genetics, 172(4), 2391-403.
  28. Morton J, Davis MW, Jorgensen EM, Carroll D (2006 Oct 31). Induction and repair of zinc-finger nuclease-targeted double-strand breaks in Caenorhabditis elegans somatic cells. Proc Natl Acad Sci U S A, 103(44), 16370-5.
  29. Carroll D, Morton JJ, Beumer KJ, Segal DJ (2006). Design, construction and in vitro testing of zinc finger nucleases. Nat Protoc, 1(3), 1329-41.
  30. Lloyd A, Plaisier CL, Carroll D, Drews GN (2005 Feb 8). Targeted mutagenesis using zinc-finger nucleases in Arabidopsis. Proc Natl Acad Sci U S A, 102(6), 2232-7.
  31. Bibikova M, Beumer K, Trautman JK, Carroll D (2003 May 2). Enhancing gene targeting with designed zinc finger nucleases. Science, 300(5620), 764.
  32. Bibikova M, Golic M, Golic KG, Carroll D (2002 Jul). Targeted chromosomal cleavage and mutagenesis in Drosophila using zinc-finger nucleases. Genetics, 161(3), 1169-75.
  33. Costanzo V, Robertson K, Bibikova M, Kim E, Grieco D, Gottesman M, Carroll D, Gautier J (2001 Jul). Mre11 protein complex prevents double-strand break accumulation during chromosomal DNA replication. Mol Cell, 8(1), 137-47.
  34. Christensen S, Pont-Kingdon G, Carroll D (2001). Comparative studies of the endonucleases from two related Xenopus laevis Retrotransposons, Tx1L and Tx2L: Target site specificity and evolutionary implications. Genetica, 110, 245-56.
  35. Bibikova M, Carroll D, Segal DJ, Trautman JK, Smith J, Kim Y-G, Chandrasegaran S (2001). Stimulation of homologous recombination through targeted cleavage by a chimeric nuclease. Mol Cell Biol, 21, 289-97.
  36. Faruqi AF, Datta HJ, Carroll D, Seidman MM, Glazer PM (2000 Feb). Triple-helix formation induces recombination in mammalian cells via a nucleotide excision repair-dependent pathway. Mol Cell Biol, 20(3), 990-1000.
  37. Smith J, Bibikova M, Whitby FG, Reddy AR, Chandrasegaran S, Carroll D (2000 Sep 1). Requirements for double-strand cleavage by chimeric restriction enzymes with zinc finger DNA-recognition domains. Nucleic Acids Res, 28(17), 3361-9.
  38. Christensen S, Pont-Kingdon G, Carroll D (2000). Target specificity of the endonuclease from the Xenopus laevis non-LTR retrotransposon, Tx1L. Mol Cell Biol, 20, 1219-26.
  39. Pont-Kingdon G, Chi E, Christensen S, Carroll D (1998). RNA expression from a site-specific non-LTR retrotransposon microinjected into Xenopus oocytes. Genetica, 104, 67-76.
  40. Bibikova M, Wu B, Chi E, Kim K-H, Trautman JK, Carroll D (1998). Characterization of FEN-1 from Xenopus laevis. cDNA cloning and role in DNA metabolism. J Biol Chem, 273, 34222-9.
  41. Segal DJ, Faruqi AF, Glazer PM, Carroll D (1997). Processing of targeted psoralen crosslinks in Xenopus oocytes. Mol Cell Biol, 17, 6645-52.
  42. Pont-Kingdon G, Chi E, Christensen S, Carroll D (1997). Ribonucleoprotein formation by the ORF1 protein of the non-LTR retrotransposon Tx1L in Xenopus oocytes. Nucleic Acids Res, 25, 3088-94.
  43. Carroll D, Ring C, Shrimpton J, Evans P, Willemsen G, Hucklebridge F (1996). Secretory immunoglobulin A and cardiovascular responses to acute psychological challenge. Int J Behav Med, 3(3), 266-79.
  44. Faruqi AF, Seidman MM, Segal DJ, Carroll D, Glazer PM (1996). Recombination induced by triple helix-targeted DNA damage in mammalian cells. Mol Cell Biol, 16, 6820-8.
  45. Segal DJ, Carroll D (1995). Endonuclease-induced, targeted homologous extrachromosomal recombination in Xenopus oocytes. Proc Natl Acad Sci U S A, 92, 806-10.
  46. Lehman CW, Jeong-Yu S, Trautman JK, Carroll D (1994). Repair of heteroduplex DNA in Xenopus laevis oocytes. Genetics, 138, 459-70.
  47. Carroll D, Lehman CW, Jeong-Yu S, Dohrmann P, Dawson RJ, Trautman JK (1994). Distribution of exchanges upon homologous recombination of exogenous DNA in Xenopus laevis oocytes. Genetics, 138, 445-57.
  48. Lehman CW, Trautman JK, Carroll D (1994). Illegitimate recombination in Xenopus: Characterization of the end-joined junctions. Nucleic Acids Res, 22, 434-42.
  49. Lehman CW, Clemens M, Worthylake DK, Trautman JK, Carroll D (1993). Homologous and illegitimate recombination in developing Xenopus oocytes and eggs. Mol Cell Biol, 13, 6897-906.
  50. Lehman CW, Carroll D (1993). Isolation of large quantities of functional, cytoplasm-free Xenopus laevis oocyte nuclei. Anal Biochem, 211, 311-9.
  51. Pont-Kingdon G, Dawson RJ, Carroll D (1993). Intermediates in extrachromosomal homologous recombination in Xenopus laevis oocytes: Characterization by electron microscopy. EMBO J, 12, 23-34.
  52. Jeong-Yu, S, Carroll D (1992). The effect of terminal nonhomologies on homologous recombination in Xenopus laevis oocytes. Mol Cell Biol, 12, 5426-37.
  53. Jeong-Yu, S, Carroll D (1992). Test of the double-strand-break repair model of recombination in Xenopus laevis oocytes. Mol Cell Biol, 12, 112-9.
  54. Lehman CW, Carroll D (1991). Homologous recombination catalyzed by a nuclear extract from Xenopus oocytes. Proc Natl Acad Sci U S A, 88, 10840-4.
  55. Maryon E, Carroll D (1991). Characterization of recombination intermediates from DNA injected into Xenopus laevis oocytes: Evidence for a nonconservative mechanism of homologous recombination. Mol Cell Biol, 11, 3278-87.
  56. Maryon E, Carroll D (1991). Involvement of single-stranded tails in homologous recombination of DNA injected into Xenopus laevis oocyte nuclei. Mol Cell Biol, 111, 3268-77.
  57. Urnes MS, Carroll D (1990). Amylase synthesis as a simple model system for translation and hybrid arrest in Xenopus oocytes. Gene, 95, 267-74.
  58. Sweigert SE, Carroll D (1990). Repair and recombination of X-irradiated plasmids in Xenopus laevis oocytes. Mol Cell Biol, 10, 5849-56.
  59. Maryon EB, Carroll D (1989). Degradation of linear DNA by a strand-specific exonuclease activity in Xenopus laevis oocytes. Mol Cell Biol, 9, 4862-71.
  60. Garrett JE, Knutzon DS, Carroll D (1989). Composite transposable elements in the Xenopus laevis genome. Mol Cell Biol, 9, 3018-27.
  61. Grzesiuk E, Carroll D (1987). Recombination of DNAs in Xenopus oocytes based on short homologous overlaps. Nucleic Acids Res, 15, 971-85.
  62. Carroll D, Wright SH, Wolff R, Grzesiuk E, Maryon EB (1986). Efficient homologous recombination of linear DNA substrates after injection into Xenopus laevis oocytes. Mol Cell Biol, 6, 2053-61.
  63. Garrett JE, Carroll D (1986). Tx1: A transposable element from Xenopus laevis with some unusual properties. Mol Cell Biol, 6, 933-41.
  64. Carroll D, Garrett JE, Lam BS (1984 Feb). Isolated clusters of paired tandemly repeated sequences in the Xenopus laevis genome. Mol Cell Biol, 4(2), 254-9.
  65. Swindle J, Ajioka J, Dawson D, Myers R, Carroll D, Georgopoulos C (1984 Jun 25). The nucleotide sequence of the Escherichia coli K12 nusB (groNB) gene. Nucleic Acids Res, 12(12), 4977-85.
  66. Carroll D, Wright SH, Ajioka RS, Hussey CE Jr (1984 Sep 15). Genetic recombination of Xenopus laevis 5 S DNA in bacteria. J Mol Biol, 178(2), 155-72.
  67. Young D, Carroll D (1983 Apr). Regular arrangement of nucleosomes on 5S rRNA genes in Xenopus laevis. Mol Cell Biol, 3(4), 720-30.
  68. Lam BS, Carroll D (1983 Apr 25). Tandemly repeated DNA sequences from Xenopus laevis. I. Studies on sequence organization and variation in satellite 1 DNA (741 base-pair repeat). J Mol Biol, 165(4), 567-85.
  69. Lam BS, Carroll D (1983 Apr 25). Tandemly repeated DNA sequences from Xenopus laevis. II. Dispersed clusters of a 388 base-pair repeating unit. J Mol Biol, 165(4), 587-97.
  70. Carroll D (1983 Nov). Genetic recombination of bacteriophage lambda DNAs in Xenopus oocytes. Proc Natl Acad Sci U S A, 80(22), 6902-6.
  71. ONeill FJ, Carroll D (1983). Role of defective simian virus 40 genomes in establishment and maintenance of persistently infected primate cell lines. Intervirology, 19, 181-94.
  72. ONeill FJ, Maryon EB, Carroll D (1982 Jul). Isolation and characterization of defective simian virus 40 genomes which complement for infectivity. J Virol, 43(1), 18-25.
  73. ONeill FJ, Carroll D (1981 Jul 30). Amplification of papovavirus defectives during serial low multiplicity infections. Virology, 112(2), 800-3.
  74. Carroll D, Hansen JL, Maryon EB, ONeill FJ (1981). SV40 defectives selected during low multiplicity passage in A172 human glioblastoma cells. Virology, 112, 461-71.
  75. Carroll D, Ajioka RS, Georgopoulos C (1980 Aug). Bacteriophage lambda cloning vehicles for studies of genetic recombination. Gene, 10(3), 261-71.
  76. Carroll D, Ajioka RS (1980 Aug). Recombination of a eukaryotic DNA in bacteria. Gene, 10(3), 273-81.
  77. Humphries SE, Young D, Carroll D (1979 Jul 24). Chromatin structure of the 5S ribonucleic acid genes of Xenopus laevis. Biochemistry, 18(15), 3223-31.
  78. Carroll D, ONeill FJ (1978). Genome maps of simian virus 40 defectives propagated in human glioblastoma cells. Virology, 87, 120-9.
  79. ONeill FJ, Carroll D (1978). Appearance of defective simian virus 40 following infection of cultured human glioblastoma cells. Virology, 87, 109-19.
  80. Brown DD, Carroll D, Brown RD (1977). The isolation and characterization of a second oocyte 5S DNA from Xenopus laevis. Cell, 12, 1045-56.
  81. Carroll D, Brown DD (1976 Apr). Repeating units of Xenopus laevis oocyte-type 5S DNA are heterogeneous in length. Cell, 7(4), 467-75.
  82. Carroll D, Brown DD (1976). Adjacent repeating units of Xenopus laevis 5S DNA can be heterogeneous in length. Cell, 7, 477-86.
  83. Wellauer PK, Reeder RH, Carroll D, Brown DD, Deutch A, Higashinakagawa T, Dawid IB (1974 Jul). Amplified ribosomal DNA from Xenopus laevis has heterogeneous spacer lengths. Proc Natl Acad Sci U S A, 71(7), 2823-7.
  84. Carroll D (1972 Feb 1). Complexes of polylysine with polyuridylic acid and other polynucleotides. Biochemistry, 11(3), 426-33.
  85. Carroll D (1972 Feb 1). Optical properties of deoxyribonucleic acid--polylysine complexes. Biochemistry, 11(3), 421-6.
  86. Carroll D, Botchan MR (1972 Feb 25). Competition between pentalysine and actinomycin D for binding to DNA. Biochem Biophys Res Commun, 46(4), 1661-7.
  87. Carroll D (1971 Dec). Continuous-flow salt gradient dialysis for the preparation of polynucleotide-polypeptide complexes. Anal Biochem, 44(2), 496-502.
  88. MacGillivray AJ, Carroll D, Paul J (1971 Mar 16). The heterogeneity of the non-histone chromatin proteins from mouse tissues. FEBS Lett, 13(4), 204-208.

Review

  1. Carroll D (2017 Dec). Genome Editing: Past, Present, and Future. [Review]. Yale J Biol Med, 90(4), 653-659.
  2. Carroll D (2015). Genome editing by targeted chromosomal mutagenesis. [Review]. Methods Mol Biol, 1239, 1-13.
  3. Chandrasegaran S, Carroll D (2015 Oct 23). Origins of Programmable Nucleases for Genome Engineering.LID - S0022-2836(15)00606-3 [pii]LID - 10.1016/j.jmb.2015.10.014 [doi]. [Review]. J Mol Biol.
  4. Pauwels K, Podevin N, Breyer D, Carroll D, Herman P (2014 Jan 25). Engineering nucleases for gene targeting: safety and regulatory considerations. [Review]. N Biotechnol, 31(1), 18-27.
  5. Beumer KJ, Carroll D (2014 Jun 15). Targeted genome engineering techniques in Drosophila. [Review]. Methods, 68(1), 29-37.
  6. Carroll D (2014). Genome engineering with targetable nucleases. [Review]. Annu Rev Biochem, 83, 409-39.
  7. Carroll D (2012 Sep). A CRISPR approach to gene targeting. [Review]. Mol Ther, 20(9), 1658-60.
  8. Carroll D (2011 Aug). Genome engineering with zinc-finger nucleases. [Review]. Genetics, 188(4), 773-82.
  9. Carroll D (2011 Feb). Zinc-finger nucleases: a panoramic view. [Review]. Curr Gene Ther, 11(1), 2-10.
  10. Carroll D (). Zinc-finger Nucleases: Powerful Tools for Gene Targeting. [Review]. GIT Laboratory Journal Europe, 7(8), 20-21.
  11. Carroll D (2008 Nov). Progress and prospects: zinc-finger nucleases as gene therapy agents. [Review]. Gene Ther, 15(22), 1463-8.
  12. Porteus MH, Carroll D (2005). Gene targeting using zinc finger nucleases. [Review]. Nat Biotechnol, 23, 967-973.
  13. Carroll D, Segal DJ (1998). Induced recombination in model systems. [Review]. Curr Opin Mol Ther, 1, 593-8.
  14. Carroll D (1996). Homologous genetic recombination in Xenopus: Mechanism and implications for gene manipulation. [Review]. Prog Nucleic Acid Res Mol Biol, 54, 101-25.
  15. MacGillivray AJ, Rickwood D, Cameron A, Carroll D, Ingles CJ, Krauze RJ, Paul J (1975). Methods of isolation and characterization of chromosomal non-histone proteins. [Review]. Methods Enzymol, 40, 160-71.

Book Chapter

  1. Carroll D (). Site-directed insertion of transgenes in Drosophila. In S. Renault and P. Duchateau (Eds.), Topics in Current Genetics (23, pp. 317-326). Springer.
  2. Carroll D, Beumer KJ, Trautman JK (2010). High-efficiency gene targeting in Drosophila with zinc finger nucleases. In Journal Not Yet Confirmed (649, pp. 271-80). United States.
  3. Carroll D, Beumer KJ, Morton JJ, Bozas A, Trautman JK (2008). Gene targeting in Drosophila and Caenorhabditis elegans with zinc-finger nucleases. In Med Image Comput Comput Assist Interv (435, pp. 63-77). United States.
  4. Carroll D (2004). Using nucleases to stimulate homologous recombination. In Med Image Comput Comput Assist Interv (262, pp. 195-207). United States.
  5. Carroll D (2001). Recombinant DNA. In Brenner S, Miller JH (Eds.), Encyclopedia of Genetics. New York, NY: Academic Press.
  6. Carroll D (2001). rDNA Amplification. In Brenner S, Miller JH (Eds.), Encyclopedia of Genetics. New York NY: Academic Press.
  7. Carroll D (2001). Illegitimate Recombination. In Brenner S, Miller JH (Eds.), Encyclopedia of Genetics. New York, NY: Academic Press.
  8. Carroll D (2001). Gene Duplication. In Brenner S, Miller JH (Eds.), Encyclopedia of Genetics. New York, NY: Academic Press.
  9. Carroll D (2001). DNA Recombination. In Brenner S, Miller JH (Eds.), Encyclopedia of Genetics. New York, NY: Academic Press.
  10. Carroll D (1999). DNA recombination and repair in Xenopus oocytes and eggs: substrate design, direct microinjection, and extract preparation. In Richter JD (Ed.), A Comparative Methods Approach to the Study of Oocytes and Embryos (pp. 173-95). New York, NY: Oxford University Press.
  11. Carroll D (1997). Modes of DNA repair in Xenopus oocytes, eggs and extracts. In Hoekstra MF, Nickoloff JA (Eds.), DNA Damage and Repair -- Biochemistry, Genetics and Cell Biology (1, pp. 597-616). Totowa, NJ: Humana Press.
  12. Carroll D, Lehman CW (1991). DNA recombination and repair in oocytes, eggs and extracts. Chapter 24. In Xenopus laevis: Practical Uses in Cell and Molecular Biology (36, pp. 467-486). Academic Press.
  13. Carroll D, Knutzon DS, Garrett JE (1989). Transposable Elements in Xenopus. In Howe MM, Berg DE (Eds.), Mobile DNA (pp. 567-74). ASM Press.
  14. Paul J, Carroll D, Gilmour RS, More IAR, Threlfall G, Wilkie M, Wilson S (1972). Functional studies on chromatin. In Gene Transcription in Reproductive Tissue (pp. 277-95). 5th Karolinska Symposium on Research Methods in Reproductive Endocrinology.

Book Review

  1. Carroll D (1993). Review of Mechanisms of Eukaryotic DNA Recombination. [Review of the book Mechanisms of Eukaryotic DNA Recombination]. Biosci, 43, 639-40.
  2. Carroll D (1990). Review of Chromatin. [Review of the book ]. Chromatin, 78, 276.