Bryan W. Jones, PhD

Languages

  • English

Academic Information

  • Departments: Ophthalmology/Visual Sciences - Associate Professor

Academic Office Information

  • 801-585-5954
  • John A. Moran Eye Center
    Ophthalmology
    65 N Mario Capecchi, Room: #S3872
    Salt Lake City, UT 84132

Research Statement

Research Interests: Retinal vision, synaptic transmission, neuronal circuitry, retinal cell biology, metabolism, connectomics

Education History

Type School Degree
Postdoctoral Fellowship Moran Eye Center
Ophthalmology
Postdoctoral Fellow
Postdoctoral Fellowship Huntsman Cancer Institute
Cell Biology
Postdoctoral Fellow
Doctoral Training University of Utah
Neurophysiology
Ph.D.
Undergraduate University of Utah
Biology, Chemistry
B.S.

Selected Publications

Journal Article

  1. Pfeiffer RL, Marc RE, Jones BW (2019). Persistent remodeling and neurodegeneration in late-stage retinal degeneration. (Epub ahead of print) Prog Retin Eye Res.
  2. Tong J, Phu J, Khuu SK, Yoshioka N, Choi AY, Nivison-Smith L, Marc RE, Jones BW, Pfeiffer RL, Kalloniatis M, Zangerl B (2019). Development of a spatial model of age-related change in the macular ganglion cell layer to predict function from structural changes. (Epub ahead of print) Am J Ophthalmol.
  3. Heng JS, Rattner A, Stein-OBrien GL, Winer BL, Jones BW, Vernon HJ, Goff LA, Nathans J (2019). Hypoxia tolerance in the Norrin-deficient retina and the chronically hypoxic brain studied at single-cell resolution. Proc Natl Acad Sci U S A, 116(18), 9103-9114.
  4. Lauritzen JS, Sigulinsky CL, Anderson JR, Kalloniatis M, Nelson NT, Emrich DP, Rapp C, McCarthy N, Kerzner E, Meyer M, Jones BW, Marc RE (2016). Rod-cone crossover connectome of mammalian bipolar cells. J Comp Neurol, 527(1), 87-116.
  5. Marc RE, Sigulinsky CL, Pfeiffer RL, Emrich D, Anderson JR, Jones BW (2018). Heterocellular Coupling Between Amacrine Cells and Ganglion Cells. Front Neural Circuits, 12, 90.
  6. Nagarajan N, Jones BW, West PJ, Marc RE, Capecchi MR (2017). Corticostriatal circuit defects in Hoxb8 mutant mice. Mol Psychiatry, 23(9), 1868-1877.
  7. Phu J, Khuu SK, Nivison-Smith L, Zangerl B, Choi AYJ, Jones BW, Pfeiffer RL, Marc RE, Kalloniatis M (2017). Pattern Recognition Analysis Reveals Unique Contrast Sensitivity Isocontours Using Static Perimetry Thresholds Across the Visual Field. Invest Ophthalmol Vis Sci, 58(11), 4863-4876.
  8. Yoshioka N, Zangerl B, Nivison-Smith L, Khuu SK, Jones BW, Pfeiffer RL, Marc RE, Kalloniatis M (2017). Pattern Recognition Analysis of Age-Related Retinal Ganglion Cell Signatures in the Human Eye. Invest Ophthalmol Vis Sci, 58(7), 3086-3099.
  9. Kerzner E, Lex A, Sigulinsky CL, Umess T, Jones BW, Marc RE, Meyer M (2017). Graffinity: Visualizing Connectivity in Large Graphs. Comput Graph Forum, 36(3), 251-260.
  10. Wahlin KJ, Maruotti JA, Sripathi SR, Ball J, Angueyra JM, Kim C, Grebe R, Li W, Jones BW, Zack DJ (2017). Photoreceptor Outer Segment-like Structures in Long-Term 3D Retinas from Human Pluripotent Stem Cells. Sci Rep, 7(1), 766.
  11. Merriman DK, Sajdak BS, Li W, Jones BW (2016). Seasonal and post-trauma remodeling in cone-dominant ground squirrel retina. Exp Eye Res, 150, 90-105.
  12. Jones BW, Pfeiffer RL, Ferrell WD, Watt CB, Marmor M, Marc RE (2016). Retinal remodeling in human retinitis pigmentosa. Exp Eye Res, 150, 149-65.
  13. Pfeiffer RL, Marc RE, Kondo M, Terasaki H, Jones BW (2016). Müller cell metabolic chaos during retinal degeneration. Exp Eye Res, 150, 62-70.
  14. Jones BW, Pfeiffer RL, Ferrell WD, Watt CB, Tucker J, Marc RE (2016). Retinal Remodeling and Metabolic Alterations in Human AMD. Front Cell Neurosci, 10, 103.
  15. Woodell A, Jones BW, Williamson T, Schnabolk G, Tomlinson S, Atkinson C, Rohrer B (2016). A Targeted Inhibitor of the Alternative Complement Pathway Accelerates Recovery From Smoke-Induced Ocular Injury. Invest Ophthalmol Vis Sci, 57(4), 1728-37.
  16. Marc RE, Jones BW, Watt CB, Anderson JR, Sigulinsky C, Lauritzen S (2013). Retinal connectomics: towards complete, accurate networks. Prog Retin Eye Res, 37, 141-62.
  17. Lauritzen JS, Anderson JR, Jones BW, Watt CB, Mohammed S, Hoang JV, Marc RE (2012). ON cone bipolar cell axonal synapses in the OFF inner plexiform layer of the rabbit retina. J Comp Neurol, 521(5), 977-1000.
  18. Barabas P, Liu A, Xing W, Chen CK, Tong Z, Watt CB, Jones BW, Bernstein PS, Kriaj D (2013). Role of ELOVL4 and very long-chain polyunsaturated fatty acids in mouse models of Stargardt type 3 retinal degeneration. Proc Natl Acad Sci U S A, 110(13), 5181-6.
  19. Marc RE, Jones BW, Lauritzen JS, Watt CB, Anderson JR (2012). Building retinal connectomes. Curr Opin Neurobiol, 22(4), 568-74.
  20. Jones BW, Kondo M, Terasaki H, Lin Y, McCall M, Marc RE (2012). Retinal remodeling. Jpn J Ophthalmol, 56(4), 289-306.
  21. Lin Y, Jones BW, Liu A, Vazquz-Chona FR, Lauritzen JS, Ferrell WD, Marc RE (2012). Rapid glutamate receptor 2 trafficking during retinal degeneration. Mol Neurodegener, 7, 7.
  22. Lin Y, Jones BW, Liu A, Tucker JF, Rapp K, Luo L, Baehr W, Bernstein PS, Watt CB, Yang JH, Shaw MV, Marc RE (2011). Retinoid receptors trigger neuritogenesis in retinal degenerations. FASEB J, 26(1), 81-92.
  23. Jones BW, Kondo M, Terasaki H, Watt CB, Rapp K, Anderson J, Lin Y, Shaw MV, Yang JH, Marc RE (2011). Retinal remodeling in the Tg P347L rabbit, a large-eye model of retinal degeneration. J Comp Neurol, 519(14), 2713-33.
  24. Anderson JR, Jones BW, Watt CB, Shaw MV, Yang JH, Demill D, Lauritzen JS, Lin Y, Rapp KD, Mastronarde D, Koshevoy P, Grimm B, Tasdizen T, Whitaker R, Marc RE (2011). Exploring the retinal connectome. Mol Vis, 17, 355-79.
  25. Anderson JR, Mohammed S, Grimm B, Jones BW, Koshevoy P, Tasdizen T, Whitaker R, Marc RE (2010). The Viking viewer for connectomics: scalable multi-user annotation and summarization of large volume data sets. J Microsc, 241(1), 13-28.
  26. Tasdizen T, Koshevoy P, Grimm BC, Anderson JR, Jones BW, Watt CB, Whitaker RT, Marc RE (2010). Automatic mosaicking and volume assembly for high-throughput serial-section transmission electron microscopy. J Neurosci Methods, 193(1), 132-44.
  27. Anderson JR, Jones BW, Yang JH, Shaw MV, Watt CB, Koshevoy P, Spaltenstein J, Jurrus E, U V K, Whitaker RT, Mastronarde D, Tasdizen T, Marc RE (2009). A computational framework for ultrastructural mapping of neural circuitry. PLoS Biol, 7(3), e1000074.
  28. Jurrus E, Whitaker R, Jones BW, Marc R, Tasdizen T (2009). AN OPTIMAL-PATH APPROACH FOR NEURAL CIRCUIT RECONSTRUCTION. Proc IEEE Int Symp Biomed Imaging, 2008(4541320), 1609-1612.
  29. Marc RE, Jones BW, Watt CB, Vazquez-Chona F, Vaughan DK, Organisciak DT (2008). Extreme retinal remodeling triggered by light damage: implications for age related macular degeneration. Mol Vis, 14, 782-806.
  30. Marc RE, Jones BW, Anderson JR, Kinard K, Marshak DW, Wilson JH, Wensel T, Lucas RJ (2007). Neural reprogramming in retinal degeneration. Invest Ophthalmol Vis Sci, 48(7), 3364-71.

Review

  1. Jones BW, Marc RE, Pfeiffer RL, Kolb H, Fernandez E, Nelson R (1995). Retinal Degeneration, Remodeling and Plasticity. [Review].

Editorial

  1. Jones BW, Lewis GP (2016). Special issue on retinal remodeling. Exp Eye Res, 150, 1-3.

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