Karen Curtin, PhD, MStat

Research Interests

  • Gene-Environment Interaction
  • Cancer Epidemiology with Emphasis on Colorectal Cancer
  • Environmental Pollution
  • Epigenetics in Cancer
  • Age-related macular degeneration and co-segregating diseases


Lab Website


  • English
  • Modern Greek (1453-)
  • Spanish

Academic Information

  • Departments: Family & Preventive Medicine - Adjunct Associate Professor, Internal Medicine - Research Associate Professor, Ophthalmology/Visual Sciences - Adjunct Associate Professor
  • Divisions: Epidemiology, Public Health
  • Cancer Center Programs: Cancer Control & Population Sciences

Academic Office Information

  • 801-585-5320
  • Huntsman Cancer Hospital
    Utah Population Database (UPDB)
    1950 Circle of Hope, Room: HCI Research So Rm 1511
    Salt Lake City, UT 84112

Academic Bio

Karen Curtin (Ph.D., M.Stat.) is an Associate Professor in the Department of Internal Medicine, Division of Epidemiology and adjunct Associate Professor in Ophthalmology and Visual Sciences at the University of Utah School of Medicine and the John A. Moran Eye Center. Dr. Curtin serves as Associate Director of the Utah Population Database (UPDB), a unique shared resource housed at the University of Utah's Huntsman Cancer Institute where she is affiliated with Pedigree and Population Resource, the group that administers and supports research using the database. She is a Co-Investigator with the Steele Center for Translational Medicine at the Moran Eye Center and is adjunct faculty in the Division of Public Health where she serves on the Master of Biostatistics committee. Through her many affiliations Dr. Curtin, a genetic epidemiologist and population-based scientist, collaborates widely with investigators across the University of Utah Health Sciences Center, Huntsman Cancer Institute, Intermountain Healthcare, and other academic institutions. Dr. Curtin is a Huntsman Cancer Institute investigator and member of the Cancer Control and Population Sciences program, with a keen interest in the interaction of genetic, environmental, and molecular risk factors in the development of cancer and predisposing conditions.

Her wide array of research interests and experience in research infrastructure and project development have resulted several in cross-disciplinary collaborations. Focused on preventive and translational research, she is currently investigating mammographic breast density in relation to interval breast cancer and endocrine therapy-induced changes in breast density in a statewide cohort of women. Dr. Curtin is conducting population-based research to elucidate the genetic underpinnings of myeloid disorders and malignancies utilizing multigenerational, high-risk pedigrees unique to Utah. She established ongoing and productive collaborations with renowned translational and clinical investigators in age-related macular degeneration and exfoliation syndrome/glaucoma and associated comorbidities. She continues to pursue population-based investigations in gastrointestinal cancers with colleagues at the University of Utah and Mayo Clinic, and previously partnered with College of Pharmacy and Intermountain Healthcare to investigate a statewide cohort of amphetamine-type stimulant users to examine future incidence of Parkinson's disease.

Dr. Curtin received her PhD in biomedical informatics with an emphasis in genetic epidemiology from the University of Utah, where she was awarded the John D. Morgan Fellowship Award in Biomedical Informatics. Following post-doctoral training in molecular and risk factor epidemiology at Utah, Dr. Curtin received a faculty appointment in the Department of Internal Medicine. Prior to pursuing an academic career, she was a Master's level biostatistician on several large, population-based cancer studies. A prolific and extensively published researcher, Dr. Curtin is principal investigator of several internally and externally funded studies. She was invited to speak at the prestigious Lindberg Society Symposium at the 2018 World Ophthalmology Congress and recently received an award from the BrightFocus(R) Foundation's National Glaucoma Research Program to study prognostic factors and predictive markers of progression to exfoliation glaucoma in exfoliation syndrome.

Education History

Type School Degree
Doctoral Training University of Utah School of Medicine, Clinical and Translational Track: Genetic Epidemiology
Biomedical Informatics
Graduate Training University of Utah, College of Social and Behavioral Sciences
Econometrics and Statistics
Undergraduate University of Utah, College of Business
Economics, Magna Cum Laude

Selected Publications

Journal Article

  1. Samadder NJ, Smith KR, Wong J, Burt RW, Curtin K (2020). Colorectal cancer in the setting of pregnancy and familial risk. (Epub ahead of print) Int J Colorectal Dis.
  2. VanDerslice J, Taddie MC, Curtin K, Miller C, Yu Z, Hemmert R, Cannon-Albright LA, Neklason DW (2020). Early life exposures associated with risk of small intestinal neuroendocrine tumors. PLoS ONE, 15(4), e0231991.
  3. Rogers CR, Blackburn BE, Huntington M, Curtin K, Thorpe RJ Jr, Rowe K, Snyder J, Deshmukh V, Newman M, Fraser A, Smith K, Hashibe M (2020). Rural-urban disparities in colorectal cancer survival and risk among men in Utah: a statewide population-based study. Cancer Causes Control, 31(3), 241-253.
  4. Moore A, Kane E, Wang Z, Panagiotou OA, Teras LR, Monnereau A, Wong Doo N, Machiela MJ, Skibola CF, Slager SL, Salles G, Camp NJ, Bracci PM, Nieters A, Vermeulen RCH, Vijai J, Smedby KE, Zhang Y, Vajdic CM, Cozen W, Spinelli JJ, Hjalgrim H, Giles GG, Link BK, Clavel J, Arslan AA, Purdue MP, Tinker LF, Albanes D, Ferri GM, Habermann TM, Adami HO, Becker N, Benavente Y, Bisanzi S, Boffetta P, Brennan P, Brooks-Wilson AR, Canzian F, Conde L, Cox DG, Curtin K, Foretova L, Gapstur SM, Ghesquires H, Glenn M, Glimelius B, Jackson RD, Lan Q, Liebow M, Maynadie M, McKay J, Melbye M, Miligi L, Milne RL, Molina TJ, Morton LM, North KE, Offit K, Padoan M, Patel AV, Piro S, Ravichandran V, Riboli E, de Sanjose S, Severson RK, Southey MC, Staines A, Stewart C, Travis RC, Weiderpass E, Weinstein S, Zheng T, Chanock SJ, Chatterjee N, Rothman N, Birmann BM, Cerhan JR, Berndt SI (2020). Genetically Determined Height and Risk of Non-hodgkin Lymphoma. Front Oncol, 9, 1539.
  5. Samadder NJ, Neklason D, Snow A, Samowitz W, Cessna MH, Rowe K, Sandhu I, Boucher K, Pappas L, Smith KR, Wong J, Curtin K, Provenzale D, Burt RW (2019). Clinical and Molecular Features of Post-Colonoscopy Colorectal Cancers. Clin Gastroenterol Hepatol, 17(13), 2731-2739.e2.
  6. Kohli DR, Smith KR, Wong J, Yu Z, Boucher K, Faigel DO, Pannala R, Burt RW, Curtin K, Samadder NJ (2019). Familial pancreatic cancer risk: a population-based study in Utah. J Gastroenterol, 54(12), 1106-1112.
  7. Curtin K, Cannon-Albright LA, VanDerslice J, Yu Z, Herget KA, Thota R, Neklason DW (2019). Associations of Tobacco and Alcohol Use with Risk of Neuroendocrine Tumors of the Small Intestine in Utah. Cancer Epidemiol Biomarkers Prev, 28(12), 1998-2004.
  8. Duensing I, Anderson MB, Meeks HD, Curtin K, Gililland JM (2019). Patients with Type-1 Diabetes Are at Greater Risk of Periprosthetic Joint Infection: A Population-Based, Retrospective, Cohort Study. J Bone Joint Surg Am, 101(20), 1860-1867.
  9. Din L, Sheikh M, Kosaraju N, Smedby KE, Bernatsky S, Berndt SI, Skibola CF, Nieters A, Wang S, McKay JD, Cocco P, Maynadi M, Foretov L, Staines A, Mack TM, de Sanjos S, Vyse TJ, Padyukov L, Monnereau A, Arslan AA, Moore A, Brooks-Wilson AR, Novak AJ, Glimelius B, Birmann BM, Link BK, Stewart C, Vajdic CM, Haioun C, Magnani C, Conti DV, Cox DG, Casabonne D, Albanes D, Kane E, Roman E, Muzi G, Salles G, Giles GG, Adami HO, Ghesquires H, De Vivo I, Clavel J, Cerhan JR, Spinelli JJ, Hofmann J, Vijai J, Curtin K, Costenbader KH, Onel K, Offit K, Teras LR, Morton L, Conde L, Miligi L, Melbye M, Ennas MG, Liebow M, Purdue MP, Glenn M, Southey MC, Din M, Rothman N, Camp NJ, Wong Doo N, Becker N, Pradhan N, Bracci PM, Boffetta P, Vineis P, Brennan P, Kraft P, Lan Q, Severson RK, Vermeulen RCH, Milne RL, Kaaks R, Travis RC, Weinstein SJ, Chanock SJ, Ansell SM, Slager SL, Zheng T, Zhang Y, Benavente Y, Taub Z, Madireddy L, Gourraud PA, Oksenberg JR, Cozen W, Hjalgrim H, Khankhanian P (2019). Genetic overlap between autoimmune diseases and non-Hodgkin lymphoma subtypes. Genet Epidemiol, 43(7), 844-863.
  10. Samadder NJ, Valentine JF, Guthery S, Singh H, Bernstein CN, Leighton JA, Wan Y, Wong J, Boucher K, Pappas L, Rowe K, Burt RW, Curtin K, Smith KR (2018). Family History Associates With Increased Risk of Colorectal Cancer in Patients With Inflammatory Bowel Diseases. Clin Gastroenterol Hepatol, 17(9), 1807-1813.e1.
  11. Curtin K, Theilen LH, Fraser A, Smith KR, Varner MW, Hageman GS (2019). Hypertensive disorders of pregnancy increase the risk of developing neovascular age-related macular degeneration in later life. Hypertens Pregnancy, 38(3), 141-148.
  12. Smith KA, Orlandi RR, Oakley G, Meeks H, Curtin K, Alt JA (2018). Long-term revision rates for endoscopic sinus surgery. Int Forum Allergy Rhinol, 9(4), 402-408.
  13. Glenn MJ, Madsen MJ, Davis E, Garner CD, Curtin K, Jones B, Williams JA, Tomasson MH, Camp NJ (2019). Elevated IgM and abnormal free light chain ratio are increased in relatives from high-risk chronic lymphocytic leukemia pedigrees. Blood Cancer J, 9(3), 25.
  14. Colonna S, Curtin K, Johnson E, Kohlmann W, Wright J, Kirchhoff A, Tavtigian S, Schiffman J (2019). Family History of Breast Cancer Associated with Breast Cancer in Survivors of Hodgkin Lymphoma. Int J Cancer Clin Res, 6(1).
  15. Curtin K, Fleckenstein AE, Keeshin BR, Yurgelun-Todd DA, Renshaw PF, Smith KR, Hanson GR (2018). Increased risk of diseases of the basal ganglia and cerebellum in patients with a history of attention-deficit/hyperactivity disorder. Neuropsychopharmacology, 43(13), 2548-2555.
  16. Besch BM, Curtin K, Ritch R, Allingham RR, Wirostko BM (2018). Association of Exfoliation Syndrome With Risk of Indirect Inguinal Hernia: The Utah Project on Exfoliation Syndrome. JAMA Ophthalmol, 136(12), 1368-1374.
  17. Wirostko B, Allingham R, Wong J, Curtin K (2018). Utah Project on Exfoliation Syndrome (UPEXS): Insight Into Systemic Diseases Associated With Exfoliation Syndrome. J Glaucoma, 27 Suppl 1, S75-S77.
  18. Jewel Samadder N, Valentine JF, Guthery S, Singh H, Bernstein CN, Wan Y, Wong J, Boucher K, Pappas L, Rowe K, Bronner M, Ulrich CM, Burt RW, Curtin K, Smith KR (2017). Colorectal Cancer in Inflammatory Bowel Diseases: A Population-Based Study in Utah. Dig Dis Sci, 62(8), 2126-2132.
  19. Aung T, Ozaki M, Lee MC, Schltzer-Schrehardt U, Thorleifsson G, Mizoguchi T, Igo RP Jr, Haripriya A, Williams SE, Astakhov YS, Orr AC, Burdon KP, Nakano S, Mori K, Abu-Amero K, Hauser M, Li Z, Prakadeeswari G, Bailey JNC, Cherecheanu AP, Kang JH, Nelson S, Hayashi K, Manabe SI, Kazama S, Zarnowski T, Inoue K, Irkec M, Coca-Prados M, Sugiyama K, Jrvel I, Schlottmann P, Lerner SF, Lamari H, Nilgn Y, Bikbov M, Park KH, Cha SC, Yamashiro K, Zenteno JC, Jonas JB, Kumar RS, Perera SA, Chan ASY, Kobakhidze N, George R, Vijaya L, Do T, Edward DP, de Juan Marcos L, Pakravan M, Moghimi S, Ideta R, Bach-Holm D, Kappelgaard P, Wirostko B, Thomas S, Gaston D, Bedard K, Greer WL, Yang Z, Chen X, Huang L, Sang J, Jia H, Jia L, Qiao C, Zhang H, Liu X, Zhao B, Wang YX, Xu L, Leruez S, Reynier P, Chichua G, Tabagari S, Uebe S, Zenkel M, Berner D, Mossbck G, Weisschuh N, Hoja U, Welge-Luessen UC, Mardin C, Founti P, Chatzikyriakidou A, Pappas T, Anastasopoulos E, Lambropoulos A, Ghosh A, Shetty R, Porporato N, Saravanan V, Venkatesh R, Shivkumar C, Kalpana N, Sarangapani S, Kanavi MR, Beni AN, Yazdani S, Lashay A, Naderifar H, Khatibi N, Fea A, Lavia C, Dallorto L, Rolle T, Frezzotti P, Paoli D, Salvi E, Manunta P, Mori Y, Miyata K, Higashide T, Chihara E, Ishiko S, Yoshida A, Yanagi M, Kiuchi Y, Ohashi T, Sakurai T, Sugimoto T, Chuman H, Aihara M, Inatani M, Miyake M, Gotoh N, Matsuda F, Yoshimura N, Ikeda Y, Ueno M, Sotozono C, Jeoung JW, Sagong M, Park KH, Ahn J, Cruz-Aguilar M, Ezzouhairi SM, Rafei A, Chong YF, Ng XY, Goh SR, Chen Y, Yong VHK, Khan MI, Olawoye OO, Ashaye AO, Ugbede I, Onakoya A, Kizor-Akaraiwe N, Teekhasaenee C, Suwan Y, Supakontanasan W, Okeke S, Uche NJ, Asimadu I, Ayub H, Akhtar F, Kosior-Jarecka E, Lukasik U, Lischinsky I, Castro V, Grossmann RP, Sunaric Megevand G, Roy S, Dervan E, Silke E, Rao A, Sahay P, Fornero P, Cuello O, Sivori D, Zompa T, Mills RA, Souzeau E, Mitchell P, Wang JJ, Hewitt AW, Coote M, Crowston JG, Astakhov SY, Akopov EL, Emelyanov A, Vysochinskaya V, Kazakbaeva G, Fayzrakhmanov R, Al-Obeidan SA, Owaidhah O, Aljasim LA, Chowbay B, Foo JN, Soh RQ, Sim KS, Xie Z, Cheong AWO, Mok SQ, Soo HM, Chen XY, Peh SQ, Heng KK, Husain R, Ho SL, Hillmer AM, Cheng CY, Escudero-Domnguez FA, Gonzlez-Sarmiento R, Martinon-Torres F, Salas A, Pathanapitoon K, Hansapinyo L, Wanichwecharugruang B, Kitnarong N, Sakuntabhai A, Nguyn HX, Nguyn GTT, Nguyn TV, Zenz W, Binder A, Klobassa DS, Hibberd ML, Davila S, Herms S, Nthen MM, Moebus S, Rautenbach RM, Ziskind A, Carmichael TR, Ramsay M, lvarez L, Garca M, Gonzlez-Iglesias H, Rodrguez-Calvo PP, Fernndez-Vega Cueto L, Oguz, Tamcelik N, Atalay E, Batu B, Aktas D, Kasm B, Wilson MR, Coleman AL, Liu Y, Challa P, Herndon L, Kuchtey RW, Kuchtey J, Curtin K, Chaya CJ, Crandall A, Zangwill LM, Wong TY, Nakano M, Kinoshita S, den Hollander AI, Vesti E, Fingert JH, Lee RK, Sit AJ, Shingleton BJ, Wang N, Cusi D, Qamar R, Kraft P, Pericak-Vance MA, Raychaudhuri S, Heegaard S, Kivel T, Reis A, Kruse FE, Weinreb RN, Pasquale LR, Haines JL, Thorsteinsdottir U, Jonasson F, Allingham RR, Milea D, Ritch R, Kubota T, Tashiro K, Vithana EN, Micheal S, Topouzis F, Craig JE, Dubina M, Sundaresan P, Stefansson K, Wiggs JL, Pasutto F, Khor CC (2017). Genetic association study of exfoliation syndrome identifies a protective rare variant at LOXL1 and five new susceptibility loci. Nat Genet, 49(7), 993-1004.
  20. Affolter K, Gligorich K, Samadder NJ, Samowitz WS, Curtin K (2017). Feasibility of Large-Scale Identification of Sessile Serrated Polyp Patients Using Electronic Records: A Utah Study. Dig Dis Sci, 62(6), 1455-1463.
  21. Alt JA, Thomas AJ, Curtin K, Wong J, Rudmik L, Orlandi RR (2017). Mortality risk in patients with chronic rhinosinusitis and its association to asthma. Int Forum Allergy Rhinol, 7(6), 591-599.
  22. Padia R, Alt JA, Curtin K, Muntz HR, Orlandi RR, Berger J, Meier JD (2016). Familial link of otitis media requiring tympanostomy tubes. Laryngoscope, 127(4), 962-966.
  23. Law PJ, Berndt SI, Speedy HE, Camp NJ, Sava GP, Skibola CF, Holroyd A, Joseph V, Sunter NJ, Nieters A, Bea S, Monnereau A, Martin-Garcia D, Goldin LR, Clot G, Teras LR, Quintela I, Birmann BM, Jayne S, Cozen W, Majid A, Smedby KE, Lan Q, Dearden C, Brooks-Wilson AR, Hall AG, Purdue MP, Mainou-Fowler T, Vajdic CM, Jackson GH, Cocco P, Marr H, Zhang Y, Zheng T, Giles GG, Lawrence C, Call TG, Liebow M, Melbye M, Glimelius B, Mansouri L, Glenn M, Curtin K, Diver WR, Link BK, Conde L, Bracci PM, Holly EA, Jackson RD, Tinker LF, Benavente Y, Boffetta P, Brennan P, Maynadie M, McKay J, Albanes D, Weinstein S, Wang Z, Caporaso NE, Morton LM, Severson RK, Riboli E, Vineis P, Vermeulen RC, Southey MC, Milne RL, Clavel J, Topka S, Spinelli JJ, Kraft P, Ennas MG, Summerfield G, Ferri GM, Harris RJ, Miligi L, Pettitt AR, North KE, Allsup DJ, Fraumeni JF, Bailey JR, Offit K, Pratt G, Hjalgrim H, Pepper C, Chanock SJ, Fegan C, Rosenquist R, de Sanjose S, Carracedo A, Dyer MJ, Catovsky D, Campo E, Cerhan JR, Allan JM, Rothman N, Houlston R, Slager S (2017). Genome-wide association analysis implicates dysregulation of immunity genes in chronic lymphocytic leukaemia. Nat Commun, 8, 14175.
  24. Samadder NJ, Smith KR, Wong J, Hanson H, Boucher K, Burt RW, Charlton M, Byrne KR, Gallegos-Orozco JF, Koptiuch C, Curtin K (2016). Familial Risk of Biliary Tract Cancers: A Population-Based Study in Utah. Dig Dis Sci, 61(12), 3627-3632.
  25. Rand KA, Song C, Dean E, Serie DJ, Curtin K, Sheng X, Hu D, Huff CA, Bernal-Mizrachi L, Tomasson MH, Ailawadhi S, Singhal S, Pawlish K, Peters ES, Bock CH, Stram A, Van Den Berg DJ, Edlund CK, Conti DV, Zimmerman T, Hwang AE, Huntsman S, Graff J, Nooka A, Kong Y, Pregja SL, Berndt SI, Blot WJ, Carpten J, Casey G, Chu L, Diver WR, Stevens VL, Lieber MR, Goodman PJ, Hennis AJ, Hsing AW, Mehta J, Kittles RA, Kolb S, Klein EA, Leske C, Murphy AB, Nemesure B, Neslund-Dudas C, Strom SS, Vij R, Rybicki BA, Stanford JL, Signorello LB, Witte JS, Ambrosone CB, Bhatti P, John EM, Bernstein L, Zheng W, Olshan AF, Hu JJ, Ziegler RG, Nyante SJ, Bandera EV, Birmann BM, Ingles SA, Press MF, Atanackovic D, Glenn MJ, Cannon-Albright LA, Jones B, Tricot G, Martin TG, Kumar SK, Wolf JL, Deming Halverson SL, Rothman N, Brooks-Wilson AR, Rajkumar SV, Kolonel LN, Chanock SJ, Slager SL, Severson RK, Janakiraman N, Terebelo HR, Brown EE, De Roos AJ, Mohrbacher AF, Colditz GA, Giles GG, Spinelli JJ, Chiu BC, Munshi NC, Anderson KC, Levy J, Zonder JA, Orlowski RZ, Lonial S, Camp NJ, Vachon CM, Ziv E, Stram DO, Hazelett DJ, Haiman CA, Cozen W (2016). A Meta-analysis of Multiple Myeloma Risk Regions in African and European Ancestry Populations Identifies Putatively Functional Loci. Cancer Epidemiol Biomarkers Prev, 25(12), 1609-1618.
  26. Wirostko BM, Curtin K, Ritch R, Thomas S, Allen-Brady K, Smith KR, Hageman GS, Allingham RR (2016). Risk for Exfoliation Syndrome in Women With Pelvic Organ Prolapse : A Utah Project on Exfoliation Syndrome (UPEXS) Study. JAMA Ophthalmol, 134(11), 1255-1262.
  27. Padia R, Curtin K, Peterson K, Orlandi RR, Alt J (2016). Eosinophilic esophagitis strongly linked to chronic rhinosinusitis. Laryngoscope, 126(6), 1279-83.
  28. Machiela MJ, Lan Q, Slager SL, Vermeulen RC, Teras LR, Camp NJ, Cerhan JR, Spinelli JJ, Wang SS, Nieters A, Vijai J, Yeager M, Wang Z, Ghesquires H, McKay J, Conde L, de Bakker PI, Cox DG, Burdett L, Monnereau A, Flowers CR, De Roos AJ, Brooks-Wilson AR, Giles GG, Melbye M, Gu J, Jackson RD, Kane E, Purdue MP, Vajdic CM, Albanes D, Kelly RS, Zucca M, Bertrand KA, Zeleniuch-Jacquotte A, Lawrence C, Hutchinson A, Zhi D, Habermann TM, Link BK, Novak AJ, Dogan A, Asmann YW, Liebow M, Thompson CA, Ansell SM, Witzig TE, Tilly H, Haioun C, Molina TJ, Hjalgrim H, Glimelius B, Adami HO, Roos G, Bracci PM, Riby J, Smith MT, Holly EA, Cozen W, Hartge P, Morton LM, Severson RK, Tinker LF, North KE, Becker N, Benavente Y, Boffetta P, Brennan P, Foretova L, Maynadie M, Staines A, Lightfoot T, Crouch S, Smith A, Roman E, Diver WR, Offit K, Zelenetz A, Klein RJ, Villano DJ, Zheng T, Zhang Y, Holford TR, Turner J, Southey MC, Clavel J, Virtamo J, Weinstein S, Riboli E, Vineis P, Kaaks R, Boeing H, Tjnneland A, Angelucci E, Di Lollo S, Rais M, De Vivo I, Giovannucci E, Kraft P, Huang J, Ma B, Ye Y, Chiu BC, Liang L, Park JH, Chung CC, Weisenburger DD, Fraumeni JF Jr, Salles G, Glenn M, Cannon-Albright L, Curtin K, Wu X, Smedby KE, de Sanjose S, Skibola CF, Berndt SI, Birmann BM, Chanock SJ, Rothman N (2016). Genetically predicted longer telomere length is associated with increased risk of B-cell lymphoma subtypes. Hum Mol Genet, 25(8), 1663-76.
  29. Berndt SI, Camp NJ, Skibola CF, Vijai J, Wang Z, Gu J, Nieters A, Kelly RS, Smedby KE, Monnereau A, Cozen W, Cox A, Wang SS, Lan Q, Teras LR, Machado M, Yeager M, Brooks-Wilson AR, Hartge P, Purdue MP, Birmann BM, Vajdic CM, Cocco P, Zhang Y, Giles GG, Zeleniuch-Jacquotte A, Lawrence C, Montalvan R, Burdett L, Hutchinson A, Ye Y, Call TG, Shanafelt TD, Novak AJ, Kay NE, Liebow M, Cunningham JM, Allmer C, Hjalgrim H, Adami HO, Melbye M, Glimelius B, Chang ET, Glenn M, Curtin K, Cannon-Albright LA, Diver WR, Link BK, Weiner GJ, Conde L, Bracci PM, Riby J, Arnett DK, Zhi D, Leach JM, Holly EA, Jackson RD, Tinker LF, Benavente Y, Sala N, Casabonne D, Becker N, Boffetta P, Brennan P, Foretova L, Maynadie M, McKay J, Staines A, Chaffee KG, Achenbach SJ, Vachon CM, Goldin LR, Strom SS, Leis JF, Weinberg JB, Caporaso NE, Norman AD, De Roos AJ, Morton LM, Severson RK, Riboli E, Vineis P, Kaaks R, Masala G, Weiderpass E, Chirlaque MD, Vermeulen RCH, Travis RC, Southey MC, Milne RL, Albanes D, Virtamo J, Weinstein S, Clavel J, Zheng T, Holford TR, Villano DJ, Maria A, Spinelli JJ, Gascoyne RD, Connors JM, Bertrand KA, Giovannucci E, Kraft P, Kricker A, Turner J, Ennas MG, Ferri GM, Miligi L, Liang L, Ma B, Huang J, Crouch S, Park JH, Chatterjee N, North KE, Snowden JA, Wright J, Fraumeni JF, Offit K, Wu X, de Sanjose S, Cerhan JR, Chanock SJ, Rothman N, Slager SL (2016). Meta-analysis of genome-wide association studies discovers multiple loci for chronic lymphocytic leukemia. Nat Commun, 7, 10933.
  30. Orb Q, Curtin K, Oakley GM, Wong J, Meier J, Orlandi RR, Alt JA (2016). Familial risk of pediatric chronic rhinosinusitis. Laryngoscope, 126(3), 739-45.
  31. Samadder NJ, Smith KR, Hanson H, Pimentel R, Wong J, Boucher K, Akerley W, Gilcrease G, Ulrich CM, Burt RW, Curtin K (2016). Familial Risk in Patients With Carcinoma of Unknown Primary. JAMA Oncol, 2(3), 340-6.
  32. Samadder NJ, Curtin K, Pappas L, Boucher K, Mineau GP, Smith K, Fraser A, Wan Y, Provenzale D, Kinney AY, Ulrich C, Burt RW (2016). Risk of Incident Colorectal Cancer and Death After Colonoscopy: A Population-based Study in Utah. Clin Gastroenterol Hepatol, 14(2), 279-86.e1-2.
  33. Neklason DW, VanDerslice J, Curtin K, Cannon-Albright LA (2016). Evidence for a heritable contribution to neuroendocrine tumors of the small intestine. Endocr Relat Cancer, 23(2), 93-100.
  34. Samadder NJ, Smith KR, Hanson H, Pimentel R, Wong J, Boucher K, Ahnen D, Singh H, Ulrich CM, Burt RW, Curtin K (2015). Increased Risk of Colorectal Cancer Among Family Members of All Ages, Regardless of Age of Index Case at Diagnosis. Clin Gastroenterol Hepatol, 13(13), 2305-11.e1-2.
  35. Ziv E, Dean E, Hu D, Martino A, Serie D, Curtin K, Campa D, Aftab B, Bracci P, Buda G, Zhao Y, Caswell-Jin J, Diasio R, Dumontet C, Dudziski M, Fejerman L, Greenberg A, Huntsman S, Jamroziak K, Jurczyszyn A, Kumar S, Atanackovic D, Glenn M, Cannon-Albright LA, Jones B, Lee A, Marques H, Martin T, Martinez-Lopez J, Rajkumar V, Sainz J, Vangsted AJ, Wtek M, Wolf J, Slager S, Camp NJ, Canzian F, Vachon C (2015). Genome-wide association study identifies variants at 16p13 associated with survival in multiple myeloma patients. Nat Commun, 6, 7539.
  36. Lupo PJ, Danysh HE, Plon SE, Curtin K, Malkin D, Hettmer S, Hawkins DS, Skapek SX, Spector LG, Papworth K, Melin B, Erhardt EB, Grufferman S, Schiffman JD (2015). Family history of cancer and childhood rhabdomyosarcoma: a report from the Children's Oncology Group and the Utah Population Database. Cancer Med, 4(5), 781-90.
  37. Oakley GM, Curtin K, Orb Q, Schaefer C, Orlandi RR, Alt JA (2015). Familial risk of chronic rhinosinusitis with and without nasal polyposis: genetics or environment. Int Forum Allergy Rhinol, 5(4), 276-82.
  38. Samadder NJ, Smith KR, Mineau GP, Pimentel R, Wong J, Boucher K, Pappas L, Singh H, Ahnen D, Burt RW, Curtin K (2015). Familial colorectal cancer risk by subsite of primary cancer: a population-based study in Utah. Aliment Pharmacol Ther, 41(6), 573-80.
  39. Curtin K, Fleckenstein AE, Robison RJ, Crookston MJ, Smith KR, Hanson GR (2015). Methamphetamine/amphetamine abuse and risk of Parkinson's disease in Utah: a population-based assessment. Drug Alcohol Depend, 146, 30-8.
  40. Samadder NJ, Curtin K, Wong J, Tuohy TM, Mineau GP, Smith KR, Pimentel R, Pappas L, Boucher K, Garrido-Laguna I, Provenzale D, Burt RW (2014). Epidemiology and familial risk of synchronous and metachronous colorectal cancer: a population-based study in Utah. Clin Gastroenterol Hepatol, 12(12), 2078-84.e1-2.
  41. Samadder NJ, Curtin K, Tuohy TM, Rowe KG, Mineau GP, Smith KR, Pimentel R, Wong J, Boucher K, Burt RW (2014). Increased risk of colorectal neoplasia among family members of patients with colorectal cancer: a population-based study in Utah. Gastroenterology, 147(4), 814-821.e5; quiz e15-6.
  42. Venkatramani R, Spector LG, Georgieff M, Tomlinson G, Krailo M, Malogolowkin M, Kohlmann W, Curtin K, Fonstad RK, Schiffman JD (2014). Congenital abnormalities and hepatoblastoma: a report from the Children's Oncology Group (COG) and the Utah Population Database (UPDB). Am J Med Genet A, 164A(9), 2250-5.
  43. Oakley GM, Curtin K, Layfield L, Jarboe E, Buchmann LO, Hunt JP (2014). Increased melanoma risk in individuals with papillary thyroid carcinoma. JAMA Otolaryngol Head Neck Surg, 140(5), 423-7.
  44. Samadder NJ, Curtin K, Tuohy TM, Pappas L, Boucher K, Provenzale D, Rowe KG, Mineau GP, Smith K, Pimentel R, Kirchhoff AC, Burt RW (2014). Characteristics of missed or interval colorectal cancer and patient survival: a population-based study. Gastroenterology, 146(4), 950-60.
  45. Makar KW, Poole EM, Resler AJ, Seufert B, Curtin K, Kleinstein SE, Duggan D, Kulmacz RJ, Hsu L, Whitton J, Carlson CS, Rimorin CF, Caan BJ, Baron JA, Potter JD, Slattery ML, Ulrich CM (2013). COX-1 (PTGS1) and COX-2 (PTGS2) polymorphisms, NSAID interactions, and risk of colon and rectal cancers in two independent populations. Cancer Causes Control, 24(12), 2059-75.
  46. Curtin K, Smith KR, Fraser A, Pimentel R, Kohlmann W, Schiffman JD (2013). Familial risk of childhood cancer and tumors in the Li-Fraumeni spectrum in the Utah Population Database: implications for genetic evaluation in pediatric practice. Int J Cancer, 133(10), 2444-53.
  47. Oakley GM, Curtin K, Pimentel R, Buchmann L, Hunt J (2013). Establishing a familial basis for papillary thyroid carcinoma using the Utah Population Database. JAMA Otolaryngol Head Neck Surg, 139(11), 1171-4.
  48. Berndt SI, Skibola CF, Joseph V, Camp NJ, Nieters A, Wang Z, Cozen W, Monnereau A, Wang SS, Kelly RS, Lan Q, Teras LR, Chatterjee N, Chung CC, Yeager M, Brooks-Wilson AR, Hartge P, Purdue MP, Birmann BM, Armstrong BK, Cocco P, Zhang Y, Severi G, Zeleniuch-Jacquotte A, Lawrence C, Burdette L, Yuenger J, Hutchinson A, Jacobs KB, Call TG, Shanafelt TD, Novak AJ, Kay NE, Liebow M, Wang AH, Smedby KE, Adami HO, Melbye M, Glimelius B, Chang ET, Glenn M, Curtin K, Cannon-Albright LA, Jones B, Diver WR, Link BK, Weiner GJ, Conde L, Bracci PM, Riby J, Holly EA, Smith MT, Jackson RD, Tinker LF, Benavente Y, Becker N, Boffetta P, Brennan P, Foretova L, Maynadie M, McKay J, Staines A, Rabe KG, Achenbach SJ, Vachon CM, Goldin LR, Strom SS, Lanasa MC, Spector LG, Leis JF, Cunningham JM, Weinberg JB, Morrison VA, Caporaso NE, Norman AD, Linet MS, De Roos AJ, Morton LM, Severson RK, Riboli E, Vineis P, Kaaks R, Trichopoulos D, Masala G, Weiderpass E, Chirlaque MD, Vermeulen RC, Travis RC, Giles GG, Albanes D, Virtamo J, Weinstein S, Clavel J, Zheng T, Holford TR, Offit K, Zelenetz A, Klein RJ, Spinelli JJ, Bertrand KA, Laden F, Giovannucci E, Kraft P, Kricker A, Turner J, Vajdic CM, Ennas MG, Ferri GM, Miligi L, Liang L, Sampson J, Crouch S, Park JH, North KE, Cox A, Snowden JA, Wright J, Carracedo A, Lopez-Otin C, Bea S, Salaverria I, Martin-Garcia D, Campo E, Fraumeni JF Jr, de Sanjose S, Hjalgrim H, Cerhan JR, Chanock SJ, Rothman N, Slager SL (2013). Genome-wide association study identifies multiple risk loci for chronic lymphocytic leukemia. Nat Genet, 45(8), 868-76.
  49. Liu AY, Scherer D, Poole E, Potter JD, Curtin K, Makar K, Slattery ML, Caan BJ, Ulrich CM (2013). Gene-diet-interactions in folate-mediated one-carbon metabolism modify colon cancer risk. Mol Nutr Food Res, 57(4), 721-34.
  50. Curtin K, Samowitz WS, Ulrich CM, Wolff RK, Herrick JS, Caan BJ, Slattery ML (2011). Nutrients in folate-mediated, one-carbon metabolism and the risk of rectal tumors in men and women. Nutr Cancer, 63(3), 357-66.
  51. Curtin K, Ulrich CM, Samowitz WS, Wolff RK, Duggan DJ, Makar KW, Caan BJ, Slattery ML (2011). Candidate pathway polymorphisms in one-carbon metabolism and risk of rectal tumor mutations. Int J Mol Epidemiol Genet, 2(1), 1-8.
  52. Curtin K, Wolff RK, Herrick JS, Abo R, Slattery ML (2010). Exploring multilocus associations of inflammation genes and colorectal cancer risk using hapConstructor. BMC Med Genet, 11, 170.
  53. Slattery ML, Curtin K, Wolff RK, Herrick JS, Caan BJ, Samowitz W (2010). Diet, physical activity, and body size associations with rectal tumor mutations and epigenetic changes. Cancer Causes Control, 21(8), 1237-45.
  54. Slattery ML, Wolff RK, Herrick JS, Curtin K, Caan BJ, Samowitz W (2010). Alcohol consumption and rectal tumor mutations and epigenetic changes. Dis Colon Rectum, 53(8), 1182-9.
  55. Curtin K, Samowitz WS, Wolff RK, Ulrich CM, Caan BJ, Potter JD, Slattery ML (2009). Assessing tumor mutations to gain insight into base excision repair sequence polymorphisms and smoking in colon cancer. Cancer Epidemiol Biomarkers Prev, 18(12), 3384-8.
  56. Curtin K, Lin WY, George R, Katory M, Shorto J, Cannon-Albright LA, Smith G, Bishop DT, Cox A, Camp NJ, Colorectal Cancer Study Group (2009). Genetic variants in XRCC2: new insights into colorectal cancer tumorigenesis. Cancer Epidemiol Biomarkers Prev, 18(9), 2476-84.
  57. Curtin K, Samowitz WS, Wolff RK, Herrick J, Caan BJ, Slattery ML (2009). Somatic alterations, metabolizing genes and smoking in rectal cancer. Int J Cancer, 125(1), 158-64.
  58. Curtin K, Lin WY, George R, Katory M, Shorto J, Cannon-Albright LA, Bishop DT, Cox A, Camp NJ, Colorectal Cancer Study Group (2009). Meta association of colorectal cancer confirms risk alleles at 8q24 and 18q21. Cancer Epidemiol Biomarkers Prev, 18(2), 616-21.
  59. Curtin K, Iles MM, Camp NJ (2009). Identifying rarer genetic variants for common complex diseases: diseased versus neutral discovery panels. Ann Hum Genet, 73(1), 54-60.
  60. Curtin K, Bigler J, Slattery ML, Caan B, Potter JD, Ulrich CM (2004). MTHFR C677T and A1298C polymorphisms: diet, estrogen, and risk of colon cancer. Cancer Epidemiol Biomarkers Prev, 13(2), 285-92.


  1. Curtin K, Slattery ML, Samowitz WS (2011). CpG island methylation in colorectal cancer: past, present and future. [Review]. Patholog Res Int, 902674.

Book Chapter

  1. Curtin, K (2014). Epidemiology of colorectal adenocarcinoma. In Yantiss, RK (Eds.), Advances in surgical pathology (series). Colorectal carcinoma and tumors of the vermiform appendix (xiv 317 pages). Philadelphia: Wolters Kluwer Health/Lippincott WIlliams & Wilkins.


  1. Curtin K (12/22/2014). Methamphetamine Use Triples Parkinson's Risk. Interview with Pauline Anderson, published in Medscape Medical News - Psychiatry. Medscape Medical News.


  1. Curtin K, Theilen LH, Fraser A, Smith KR, Varner MW, Hageman GS (2019).  A new study by researchers from the John A. Moran Eye Center’s Sharon Eccles Steele Center for Translational Medicine suggests women who experienced hypertensive disorders during pregnancy are at greater risk for a blinding eye disease. John Moran Eye Center News (online) [Web]. Salt Lake City, UT.