Peter S. Shen, PhD

Research Interests

  • Cryogenic Electron Microscopy and Three-Dimensional Reconstruction (cryo-EM)
  • Structural Biology
  • Protein Quality Control


Lab Website


  • English

Academic Information

  • Departments: Biochemistry - Assistant Professor

Academic Office Information

  • 801-587-9168
  • Emma Eccles Jones Medical Research Building
    15 N Medical Dr E, Room: 4100
    Salt Lake City, UT

Education History

Type School Degree
Doctoral Training Brigham Young University
Undergraduate Brigham Young University

Selected Publications

Journal Article

  1. Cooney I, Han H, Stewart MG, Carson RH, Hansen DT, Iwasa JH, Price JC, Hill CP, Shen PS (2019). Structure of the Cdc48 segregase in the act of unfolding an authentic substrate. Science, 365(6452), 502-505.
  2. Han H, Fulcher JM, Dandey VP, Iwasa JH, Sundquist WI, Kay MS, Shen PS, Hill CP (2019). Structure of Vps4 with circular peptides and implications for translocation of two polypeptide chains by AAA+ ATPases. eLife.
  3. Sinha NK, Iwasa J, Shen PS, Bass BL (2017). Dicer uses distinct modules for recognizing dsRNA termini. Science.
  4. Han H, Monroe N, Sundquist WI, Shen PS, Hill CP (2017). The AAA ATPase Vps4 binds ESCRT-III substrates through a repeating array of dipeptide-binding pockets. eLife.
  5. Monroe N, Han H, Shen PS, Sundquist WI, Hill CP (2017). Structural basis of protein translocation by the Vps4-Vta1 AAA ATPase.LID - 10.7554/eLife.24487 [doi]LID - e24487 [pii]. eLife, 6.