Markus Amann, PhD, MS

Research Interests

  • Autonomic Dysfunction
  • Cardiovascular Physiology
  • Fatigue
  • Neurosciences

Labs

Lab Website

Languages

  • English
  • German
  • Latin

Academic Information

  • Departments: Anesthesiology - Professor, Bioengineering - Adjunct Assistant Professor, Internal Medicine - Adjunct Professor
  • Divisions: Geriatrics

Academic Office Information

  • 801-582-1565-Ext.4358
  • VA - Building #2
    VA Medical Center Salt Lake City
    500 S Foothill Dr, Room: GRECC 182
    Salt Lake City, UT 84148

Academic Bio

Dr. Amann is a Professor of Anesthesiology, Theodore H. Stanley Presidential Endowed Chair in Anesthesiology, and Adjunct Professor in the Departments of Internal Medicine and Biomedical Engineering. His research focuses on the neural control of the circulation and breathing, and the etiology of central nervous system fatigue. Dr. Amann’s work aims at enhancing our understanding of the impact of cardiovascular disease on autonomic reflex function and of mechanisms determining neuromuscular fatigue during physical activity. More information about Dr. Amann's research can be found at the Utah Vascular Research Laboratory.

Education History

Type School Degree
Postdoctoral Fellowship University of Wisconsin
Pulmonary and Cardiovascular Physiology
Postdoctoral Fellow
Doctoral Training University of Utah
Integrative Physiology
Ph.D.
Graduate Training Technical University of Munich
Exercise Physiology
M.S.

Global Impact

Education History

Type School Degree Country
Graduate Training Technical University of Munich
Exercise Physiology
M.S. Germany

Selected Publications

Journal Article

  1. Hureau TJ, Weavil JC, Sidhu SK, Thurston TS, Reese VR, Zhao J, Nelson AD, Birgenheier NM, Richardson RS, Amann M (2020). Ascorbate attenuates cycling exercise-induced neuromuscular fatigue but fails to improve exertional dyspnea and exercise tolerance in COPD. (Epub ahead of print) J Appl Physiol.
  2. Amann M, Wan HY, Thurston TS, Georgescu VP, Weavil JC (2021). On the Influence of Group III/IV Muscle Afferent Feedback on Endurance Exercise Performance. Exerc Sport Sci Rev, 48(4), 209-216.
  3. Wan HY, Weavil JC, Thurston TS, Georgescu VP, Bledsoe AD, Jessop JE, Buys MJ, Richardson RS, Amann M (2020). The muscle reflex and chemoreflex interaction: ventilatory implications for the exercising human. J Appl Physiol, 129(4), 691-700.
  4. Wan HY, Weavil JC, Thurston TS, Georgescu VP, Hureau TJ, Bledsoe AD, Buys MJ, Jessop JE, Richardson RS, Amann M (2020). The exercise pressor reflex and chemoreflex interaction: cardiovascular implications for the exercising human. J Physiol, 598(12), 2311-2321.
  5. Sidhu SK, Weavil JC, Rossman MJ, Jessop JE, Bledsoe AD, Buys MJ, Supiano MS, Richardson RS, Amann M (2019). Exercise Pressor Reflex Contributes to the Cardiovascular Abnormalities Characterizing: Hypertensive Humans During Exercise. Hypertension, 74(6), 1468-1475.
  6. Hureau TJ, Weavil JC, Thurston TS, Wan HY, Gifford JR, Jessop JE, Buys MJ, Richardson RS, Amann M (2019). Pharmacological attenuation of group III/IV muscle afferents improves endurance performance when oxygen delivery to locomotor muscles is preserved. J Appl Physiol, 127(5), 1257-1266.
  7. Weavil JC, Amann M (2019). Neuromuscular fatigue during whole body exercise. Curr Opin Physiol, 10, 128-136.
  8. Hureau TJ, Romer LM, Amann M (2016). The 'sensory tolerance limit': A hypothetical construct determining exercise performance? Eur J Sport Sci, 18(1), 13-24.
  9. Weavil JC, Sidhu SK, Mangum TS, Richardson RS, Amann M (2016). Fatigue diminishes motoneuronal excitability during cycling exercise. J Neurophysiol, 116(4), 1743-1751.
  10. Sidhu SK, Weavil JC, Venturelli M, Rossman MJ, Gmelch BS, Bledsoe AD, Richardson RS, Amann M (2015). Aging alters muscle reflex control of autonomic cardiovascular responses to rhythmic contractions in humans. Am J Physiol Heart Circ Physiol, 309(9), H1479-89.
  11. Amann M, Sidhu SK, Weavil JC, Mangum TS, Venturelli M (2014). Autonomic responses to exercise: group III/IV muscle afferents and fatigue. Auton Neurosci, 188, 19-23.
  12. Sidhu SK, Weavil JC, Venturelli M, Garten RS, Rossman MJ, Richardson RS, Gmelch BS, Morgan DE, Amann M (2014). Spinal mu-opioid receptor-sensitive lower limb muscle afferents determine corticospinal responsiveness and promote central fatigue in upper limb muscle. J Physiol, 592(22), 5011-24.
  13. Hochholzer W, Valina CM, Stratz C, Amann M, Schlittenhardt D, Bttner HJ, Trenk D, Neumann FJ (2014). High-sensitivity cardiac troponin for risk prediction in patients with and without coronary heart disease. Int J Cardiol, 176(2), 444-9.
  14. Amann M, Venturelli M, Ives SJ, Morgan DE, Gmelch B, Witman MA, Jonathan Groot H, Walter Wray D, Stehlik J, Richardson RS (2014). Group III/IV muscle afferents impair limb blood in patients with chronic heart failure. Int J Cardiol, 174(2), 368-75.
  15. Dempsey JA, Blain GM, Amann M (2013). Are type III-IV muscle afferents required for a normal steady-state exercise hyperpnoea in humans? J Physiol, 592(3), 463-74.
  16. Pollak KA, Swenson JD, Vanhaitsma TA, Hughen RW, Jo D, White AT, Light KC, Schweinhardt P, Amann M, Light AR (2013). Exogenously applied muscle metabolites synergistically evoke sensations of muscle fatigue and pain in human subjects. Exp Physiol, 99(2), 368-80.
  17. Rossman MJ, Garten RS, Groot HJ, Reese V, Zhao J, Amann M, Richardson RS (2013). Ascorbate infusion increases skeletal muscle fatigue resistance in patients with chronic obstructive pulmonary disease. Am J Physiol Regul Integr Comp Physiol, 305(10), R1163-70.
  18. Rossman MJ, Groot HJ, Reese V, Zhao J, Amann M, Richardson RS (2013). Oxidative stress and COPD: the effect of oral antioxidants on skeletal muscle fatigue. Med Sci Sports Exerc, 45(7), 1235-43.
  19. Amann M (2012). Significance of Group III and IV muscle afferents for the endurance exercising human. Clin Exp Pharmacol Physiol, 39(9), 831-5.
  20. Amann M (2011). Central and peripheral fatigue: interaction during cycling exercise in humans. Med Sci Sports Exerc, 43(11), 2039-45.
  21. Lovering AT, Stickland MK, Amann M, OBrien MJ, Hokanson JS, Eldridge MW (2011). Effect of a patent foramen ovale on pulmonary gas exchange efficiency at rest and during exercise. J Appl Physiol, 110(5), 1354-61.
  22. Trinity JD, Amann M, McDaniel J, Fjeldstad AS, Barrett-OKeefe Z, Runnels S, Morgan DE, Wray DW, Richardson RS (2010). Limb movement-induced hyperemia has a central hemodynamic component: evidence from a neural blockade study. Am J Physiol Heart Circ Physiol, 299(5), H1693-700.
  23. Amann M, Blain GM, Proctor LT, Sebranek JJ, Pegelow DF, Dempsey JA (2010). Group III and IV muscle afferents contribute to ventilatory and cardiovascular response to rhythmic exercise in humans. J Appl Physiol, 109(4), 966-76.
  24. Lossnitzer D, Amann M, Zugck C, Katus H, Brtsch P, Weiss C (2008). Exercise-induced hemostatic activation in patients with dilated cardiomyopathy in sinus rhythm. Blood Coagul Fibrinolysis, 19(2), 146-52.

Review

  1. Amann M, Sidhu SK, Weavil JC, Mangum TS, Venturelli M (2015). Autonomic responses to exercise: group III/IV muscle afferents and fatigue. [Review]. Auton Neurosci, 188, 19-23.

Letter

  1. Amann M, Richardson RS, Venturelli M (2019). Reply to Drouin and Tschakovsky. [Letter to the editor]. J Appl Physiol, 126(3), 797.
  2. Amann M (2008). Viewpoint: Fatigue mechanisms determining exercise performance: integrative physiology is systems physiology. [Letter to the editor]. J Appl Physiol, 104(5), 1543.