Light, Alan R., PhD

Languages

  • English

Academic Information

  • Departments: Anesthesiology - Research Professor

Academic Office Information

  • 801-581-6393
  • School of Medicine
    Department of Anesthesiology
    30 N 1900 E, Room: 3C 444
    Salt Lake City, UT 84132

Academic Bio

Dr. Light’s lab focuses on the neurobiology of pain pathways. Most recently research projects include: 1) the role of the recently cloned Acid Sensing Ion Channels (ASICs) in muscle fatigue and pain. Research in Dr. Light’s lab has shown that ASIC-3 expression is increased following exhausting exercise, and that C-fibers innervating muscle are responsive to the mixture of metabolites that are produced by exercise. These metabolites activate a combination of purinergic (P2X), TRPV, and ASIC receptors to produce their actions. 2) experiments in patients with Fibromyalgia and Chronic Fatigue syndromes indicate that the receptors described above are dysregulated, and may provide the basis for the symptoms in these syndromes. 3) quantitative mRNA experiments suggest that the above receptors can be used as an objective marker for these and other fatigue related syndromes. 4) exercise experiments in humans indicate that the receptors described above also play a role in detecting fatigue and muscle pain both acutely, and in inflammatory and exercise induced fatigue and muscle pain.

Education History

Type School Degree
Postdoctoral Fellowship University of North Carolina
Neurophysiology		 Postdoctoral Fellow
Doctoral Training SUNY at Upstate Medical Center
Physiology		 Ph.D.
Undergraduate Hamilton College
Biology		 B.A.

Selected Publications

Journal Article

  1. Yao Y, Tan YH, Light AR, Mao J, Yu AC, Fu KY (2016 Aug). Alendronate Attenuates Spinal Microglial Activation and Neuropathic Pain. J Pain, 17(8), 889-903.
  2. Iacob E, Light AR, Donaldson GW, Okifuji A, Hughen RW, White AT, Light KC (2016 Jan). Gene Expression Factor Analysis to Differentiate Pathways Linked to Fibromyalgia, Chronic Fatigue Syndrome, and Depression in a Diverse Patient Sample. Arthritis Care Res (Hoboken), 68(1), 132-40.
  3. VanHaitsma TA, Light AR, Light KC, Hughen RW, Yenchik S, White AT (2016 Mar). Fatigue sensation and gene expression in trained cyclists following a 40 km time trial in the heat. Eur J Appl Physiol, 116(3), 541-52.
  4. Amann M, Light AR (2015 Sep). From Petri dish to human: new insights into the mechanisms mediating muscle pain and fatigue, with implications for health and disease. Exp Physiol, 100(9), 989-90.
  5. Yu H, Pan B, Weyer A, Wu HE, Meng J, Fischer G, Vilceanu D, Light AR, Stucky C, Rice FL, Hudmon A, Hogan Q (2015 Oct 21). CaMKII Controls Whether Touch Is Painful. J Neurosci, 35(42), 14086-102.
  6. Iacob E, Light KC, Tadler SC, Weeks HR, White AT, Hughen RW, Vanhaitsma TA, Bushnell L, Light AR (). Dysregulation of leukocyte gene expression in women with medication-refractory depression versus healthly non-depressed controls. Psychiatry, 13(1), 273.
  7. Pollak KA, Swenson JD, Vanhaitsma TA, Hughen RW, Jo D, Light KC, Schweinhardt P, Amann M, Light AR (). Exogenously Applied Muscle Metabolites Synergistically Evoke Sensations of Muscle Fatigue and Pain in Human Subjects. Exp Physiol.
  8. Light KC, Agarwal N, Iacob E, White AT, Kinney AY, Vanhaitsma TA, Aizad H, Hughen RW, Bateman L, Light AR (). Differing leukocyte gene expression profiles associated with fatigue in patients with prostate cancer versus chronic fatigue syndrome. Psychoneuroendocrinology.
  9. Meyer JD, Light AR, Shukla SK, Clevidence D, Yale S, Stegner AJ, Cook DB (). Post-exertion malaise in chronic fatigue syndrome: symptoms and gene expression fatigue. Biomedicine.
  10. Chen XY, Li K, Light AR, Fu KY (). Simvastatin Attenuates Formalin-Induced Nociceptive Behaviors by inhibiting Microglial RhoA and p38 MAPK Activation. J Pain, 14(11), 1310-9.
  11. Weeks HR III, Tadler SC, Smith KW, Iacob E, Saccoman M, White AT, Landvatter JD, Chelune GJ, Suchy Y, Michael EC, Cahalan MK, Bushnell L, Sakata D, Light AR, Light KC (). Antidepressant and Neurocognitive Effects of Isoflurane Anesthesia versus Electroconvulsive Therapy in Refractory Depression. PLoS ONE, 8(7), e69809.
  12. Lin Z, Marett L, Hughen RW, Flores M, Forteza I, Ammon MA, Concepcion GP, Espino S, Olivera BM, Rosenberg G, Haygood MG, Light AR, Schmidt EW (). Neuroactive diol and acyloin metabolites from cone snail-associated bacteria. Bioorg Med Chem Lett, 23(17), 4867-9.
  13. Li K, Tan YH, Light AR, Fu KY (). Different peripheral tissue injury induces differential phenotypic changes of spinal activated microglia. Clin Dev Immunol.
  14. Shapiro D, Deering-Rice CE, Romero EG, Hughen RW, Light AR, Veranth JM, Reilly CA (). Activation of transient receptor potential ankyrin-1 (TRPA1) in lung cells by wood smoke particulate material. Chem Res Toxicol, 26(5), 750-8.
  15. Yu H, Fischer G, Ferhatovic L, Light AR, Weihrauch D, Sapunar D, Nakai H, Park F, Hogan QH (). Intraganglionic AAV6 Results in Efficient and Long-Term Gene Transfer to Peripheral Sensory Nervous System in Adult Rats. PLoS ONE, 8(4), e61266.
  16. Lin Z, Torres JP, Ammon MA, Marett L, Teichert RW, Reilly CA, Kwan JC, Hughen RW, Flores M, Tianero MD, Peraud O, Cox JE, Light AR, Villaraza AJ, Haygood MG, Concepcion GP, Olivera BM, Schmidt EW (). A bacterial source for mollusk pyrone polyketides. Chem Biol, 20(1), 73-81.
  17. Tan YH, Li K, Chen XY, Cao Y, Light AR, Fu KY (). Activation of Src Family Kinases in Spinal Microglia Contributes to Formalin-Induced Persistent Pain State Through p38 Pathway. J Pain, 13(10), 1008-15.
  18. Lin Z, Flores M, Forteza I, Henriksen NM, Concepcion GP, Rosenberg G, Haygood MG, Olivera BM, Light AR, Cheatham TE, Schmidt EW (). Totopotensamides, Polyketide-cyclic peptide hybrids from a mollusk-associated bacterium streptomyces sp. J Nat Prod, 75(4), 644-9.
  19. Teichert RW, Smith NJ, Raghuraman S, Yoshikami D, Light AR, Olivera BM (). Functional profiling of neurons through cellular neuropharmacology. Proc Natl Acad Sci U S A, 109(5), 1388-95.
  20. Light KC, White AT, Tadler S, Iacob E, Light AR (2012). Genetics and Gene Expression Involving Stress and Distress Pathways in Fibromyalgia with and without Comorbid Chronic Fatigue Syndrome. Pain Res Treat, 2012, 427869.
  21. Gautam M, Benson CJ, Ranier JD, Light AR, Sluka KA (2012). ASICs Do Not Play a Role in Maintaining Hyperalgesia Induced by Repeated Intramuscular Acid Injections. Pain Res Treat, 2012, 817347.
  22. White AT, Light AR, Hughen RW, Vanhaitsma TA, Light KC (2012 Jan). Differences in metabolite-detecting, adrenergic, and immune gene expression after moderate exercise in patients with chronic fatigue syndrome, patients with multiple sclerosis, and healthy controls. Psychosom Med, 74(1), 46-54.
  23. Ahn DK, Doutova EA, McNaughton K, Light AR, Narhi M, Maixner W (2012 Apr). Functional properties of tooth pulp neurons responding to thermal stimulation. J Dent Res, 91(4), 401-6.
  24. Light AR, Bateman L, Jo D, Hughen RW, Vanhaitsma TA, White AT, Light KC (2012 Jan). Gene expression alterations at baseline and following moderate exercise in patients with Chronic Fatigue Syndrome and Fibromyalgia Syndrome. J Intern Med, 271(1), 64-81.
  25. Albright F, Ligkt K, Light A, Bateman L, Cannon-Allbright LA (). Evidence for a Heritable Predispostion to Chronic Fatigue Syndrome. BMC Neurol, 11(62).
  26. Lin Z, Reilly CA, Antemano R, Hughen RW, Marett L, Concepcion GP, Haygood MG, Olivera BM, Light A, Schmidt EW (). Nobilamides A-H, Long-Acting Transient Receptor Potential Vanilloid (TRPV1) Antagonists from Mollusk-Associated Bacteria. J Med Chem.
  27. Shin CH, Bateman L, Schlaberg R, Bunker AM, Leonard CJ, Hughen RW, Light AR, Light KC, Singh IR (2011 Jul). Absence of XMRV retrovirus and other murine leukemia virus-related viruses in patients with chronic fatigue syndrome. J Virol, 85(14), 7195-202.
  28. Deering-Rice CE, Romero EG, Shapiro D, Hughen RW, Light AR, Yost GS, Veranth JM, Reilly CA (2011 Jun 20). Electrophilic components of diesel exhaust particles (DEP) activate transient receptor potential ankyrin-1 (TRPA1): a probable mechanism of acute pulmonary toxicity for DEP. Chem Res Toxicol, 24(6), 950-9.
  29. Carruthers BM, van de Sande MI, De Meirleir KL, Klimas NG, Broderick G, Mitchell T, Staines D, Powles AC, Speight N, Vallings R, Bateman L, Baumgarten-Austrheim B, Bell DS, Carlo-Stella N, Chia J, Darragh A, Jo D, Lewis D, Light AR, Marshall-Gradisbik S, Mena I, Mikovits JA, Miwa K, Murovska M, Pall ML, Stevens S (2011 Oct). Myalgic encephalomyelitis: International Consensus Criteria. J Intern Med, 270(4), 327-338.
  30. Lin Z, Antemano RR, Hughen RW, Tianero MD, Peraud O, Haygood MG, Concepcion GP, Olovera BM, Light A, Schmidt EW (). Pulicatins A-E, neuraoactive thiazoline metabolites from cone snail-associatied bacteria. J Nat Prod, 73(11), 1922-1926.
  31. Walder RY, Rasmussen LA, Rainier JD, Light AR, Wemmie JA, Sluka KA (2010 Mar). ASIC1 and ASIC3 play different roles in the development of Hyperalgesia after inflammatory muscle injury. J Pain, 11(3), 210-8.
  32. Light AR (2010 Feb). What is this thing "fatigue" anyway? J Appl Physiol, 108(2), 464-5.
  33. Li K, Fu KY, Light AR, Mao J (2010 Apr 15). Systemic minocycline differentially influences changes in spinal microglial markers following formalin-induced nociception. J Neuroimmunol, 221(1-2), 25-31.
  34. White AT, Light AR, Hughen RW, Bateman L, Martins TB, Hill HR, Light KC (2010 Jul 1). Severity of symptom flare after moderate exercise is linked to cytokine activity in chronic fatigue syndrome. Psychophysiology, 47(4), 615-24.
  35. Li K, Lin T, Cao Y, Light AR, Fu KY (2010 Nov). Peripheral formalin injury induces 2 stages of microglial activation in the spinal cord. J Pain, 11(11), 1056-65.
  36. White AT, Lee JN, Light AR, Light KC (2009 May). Brain activation in multiple sclerosis: a BOLD fMRI study of the effects of fatiguing hand exercise. Mult Scler, 15(5), 580-6.
  37. Coryell MW, Wunsch AM, Haenfler JM, Allen JE, Schnizler M, Ziemann AE, Cook MN, Dunning JP, Price MP, Rainier JD, Liu Z, Light AR, Langbehn DR, Wemmie JA (2009 Apr 29). Acid-sensing ion channel-1a in the amygdala, a novel therapeutic target in depression-related behavior. J Neurosci, 29(17), 5381-8.
  38. Cao Y, Xie QF, Li K, Light AR, Fu KY (2009 Aug). Experimental occlusal interference induces long-term masticatory muscle hyperalgesia in rats. Pain, 144(3), 287-93.
  39. Light AR, White AT, Hughen RW, Light KC (2009 Oct). Moderate exercise increases expression for sensory, adrenergic, and immune genes in chronic fatigue syndrome patients but not in normal subjects. J Pain, 10(10), 1099-112.
  40. Peraud O, Biggs JS, Hughen RW, Light AR, Concepcion GP, Olivera BM, Schmidt EW (2009 Nov). Microhabitats within venomous cone snails contain diverse actinobacteria. Appl Environ Microbiol, 75(21), 6820-6.
  41. Vierck CJ, Yezierski RP, Light AR (2008 May 2). Long-lasting hyperalgesia and sympathetic dysregulation after formalin injection into the rat hind paw. Neuroscience, 153(2), 501-6.
  42. Light AR, Hughen RW, Zhang J, Rainier J, Liu Z, Lee J (2008 Sep). Dorsal root ganglion neurons innervating skeletal muscle respond to physiological combinations of protons, ATP, and lactate mediated by ASIC, P2X, and TRPV1. J Neurophysiol, 100(3), 1184-201.
  43. Lin T, Li K, Zhang FY, Zhang ZK, Light AR, Fu KY (2007 Dec). Dissociation of spinal microglia morphological activation and peripheral inflammation in inflammatory pain models. J Neuroimmunol, 192(1-2), 40-8.
  44. Zhang FY, Wan Y, Zhang ZK, Light AR, Fu KY (2007 Feb). Peripheral formalin injection induces long-lasting increases in cyclooxygenase 1 expression by microglia in the spinal cord. J Pain, 8(2), 110-7.
  45. Light AR, Wu Y, Hughen RW, Guthrie PB (2006 May). Purinergic receptors activating rapid intracellular Ca increases in microglia. Neuron Glia Biology, 2(2), 125-138.
  46. Chattipakorn S, Chattipakorn N, Light AR, Narhi M, Maixner W (2005 Sep). Comparison of Fos expression within the ferret's spinal trigeminal nuclear complex evoked by electrical or noxious-thermal pulpal stimulation. J Pain, 6(9), 569-80.
  47. Lamers WM, Light AR, Fine PG, Jackson KC, Fakata KL, Features Submission HC (2005). Book & media reviews. J Pain Palliat Care Pharmacother, 19(3), 101-7.
  48. Wu Y, Willcockson HH, Maixner W, Light AR (2004 Feb). Suramin inhibits spinal cord microglia activation and long-term hyperalgesia induced by formalin injection. J Pain, 5(1), 48-55.
  49. Light AR (2004 Jun). "Nocifensor" system re-revisited. Focus on "Two Types of C Nociceptor in Human Skin and Their Behavior in Areas of Capaicin-Induced Secondary Hyperalgesia". J Neurophysiol, 91(6), 2401-3.
  50. Eckert WA 3rd, McNaughton KK, Light AR (2003 Apr 7). Morphology and axonal arborization of rat spinal inner lamina II neurons hyperpolarized by mu-opioid-selective agonists. J Comp Neurol, 458(3), 240-56.
  51. Kruger L, Kavookjian AM, Kumazawa T, Light AR, Mizumura K (2003 Aug 18). Nociceptor structural specialization in canine and rodent testicular "free" nerve endings. J Comp Neurol, 463(2), 197-211.
  52. Chattipakorn SC, Sigurdsson A, Light AR, Narhi M, Maixner W (2002 Sep). Trigeminal c-Fos expression and behavioral responses to pulpal inflammation in ferrets. Pain, 99(1-2), 61-9.
  53. Eckert WA 3rd, Light AR (2002 Apr). Hyperpolarization of substantia gelatinosa neurons evoked by mu-, kappa-, delta 1-, and delta 2-selective opioids. J Pain, 3(2), 115-25.
  54. Eckert WA 3rd, Willcockson HH, Light AR (2001 Jan 12). Interference of biocytin with opioid-evoked hyperpolarization and membrane properties of rat spinal substantia gelatinosa neurons. Neurosci Lett, 297(2), 117-20.
  55. Vincler M, Maixner W, Vierck CJ, Light AR (2001 Jul-Aug). Estrous cycle modulation of nociceptive behaviors elicited by electrical stimulation and formalin. Pharmacol Biochem Behav, 69(3-4), 315-24.
  56. Fu KY, Light AR, Maixner W (2001 Feb). Long-lasting inflammation and long-term hyperalgesia after subcutaneous formalin injection into the rat hindpaw. J Pain, 2(1), 2-11.
  57. Chattipakorn SC, Light AR, Narhi M, Maixner W (2001 Dec). The effects of noxious dental heating on the jaw-opening reflex and trigeminal Fos expression in the ferret. J Pain, 2(6), 345-53.
  58. Vincler M, Maixner W, Vierck CJ Jr, Light AR (2001 Apr). Effects of systemic morphine on escape latency and a hindlimb reflex response in the rat. J Pain, 2(2), 83-90.
  59. Fu KY, Light AR, Maixner W (2000). Relationship between nociceptor activity, peripheral edema, spinal microglial activation and long-term hyperalgesia induced by formalin. Neuroscience, 101(4), 1127-35.
  60. Koerber HR, Mirnics K, Kavookjian AM, Light AR (1999 Apr). Ultrastructural analysis of ectopic synaptic boutons arising from peripherally regenerated primary afferent fibers. J Neurophysiol, 81(4), 1636-44.
  61. Fu KY, Light AR, Matsushima GK, Maixner W (1999 Apr 17). Microglial reactions after subcutaneous formalin injection into the rat hind paw. Brain Res, 825(1-2), 59-67.
  62. Chattipakorn SC, Light AR, Willcockson HH, Narhi M, Maixner W (1999 Aug). The effect of fentanyl on c-fos expression in the trigeminal brainstem complex produced by pulpal heat stimulation in the ferret. Pain, 82(2), 207-15.
  63. Vierck CJ Jr, Light AR (1999 Dec). Effects of combined hemotoxic and anterolateral spinal lesions on nociceptive sensitivity. Pain, 83(3), 447-57.
  64. Light AR, Willcockson HH (1999 Dec). Spinal laminae I-II neurons in rat recorded in vivo in whole cell, tight seal configuration: properties and opioid responses. J Neurophysiol, 82(6), 3316-26.
  65. Schneider, SP, Eckert, WA, and Light, AR (). Involvement of nucleotide 5'-triphosphates in postsynaptic responses of spinal substantia gelatinosa neurons to u-opiod receptor activation. Neurophysiology, 80, 2954-2962.
  66. Schneider SP, Eckert WA 3rd, Light AR (1998 Dec). Opioid-activated postsynaptic, inward rectifying potassium currents in whole cell recordings in substantia gelatinosa neurons. J Neurophysiol, 80(6), 2954-62.
  67. Bove, GM and Light, AR (). The nervi nervorum: missing link for neuropathic pain? Pain Forum, 6, 158-181.
  68. Alvarez FJ, Taylor-Blake B, Fyffe RE, De Blas AL, Light AR (1996 Feb 12). Distribution of immunoreactivity for the beta 2 and beta 3 subunits of the GABAA receptor in the mammalian spinal cord. J Comp Neurol, 365(3), 392-412.
  69. Smith MS, Schambra UB, Wilson KH, Page SO, Hulette C, Light AR, Schwinn DA (1995 Dec 1). alpha 2-Adrenergic receptors in human spinal cord: specific localized expression of mRNA encoding alpha 2-adrenergic receptor subtypes at four distinct levels. Brain Res Mol Brain Res, 34(1), 109-17.
  70. Willcockson HH, Taylor-Blake B, Light AR (1995). Induction of fos-like immunoreactivity by electrocutaneous stimulation of the rat hindpaw. Somatosens Mot Res, 12(2), 151-61.
  71. Vierck CJ Jr, Lee CL, Willcockson HH, Kitzmiller A, Bullitt E, Light AR (1995). Effects of anterolateral spinal lesions on escape responses of rats to hindpaw stimulation. Somatosens Mot Res, 12(2), 163-74.
  72. Bove GM, Light AR (1995). Calcitonin gene-related peptide and peripherin immunoreactivity in nerve sheaths. Somatosens Mot Res, 12(1), 49-57.
  73. Bove GM, Light AR (1995 May). Unmyelinated nociceptors of rat paraspinal tissues. J Neurophysiol, 73(5), 1752-62.
  74. Li Z, Taylor-Blake B, Light AR, Goy MF (1995 Dec). Guanylin, an endogenous ligand for C-type guanylate cyclase, is produced by goblet cells in the rat intestine. Gastroenterology, 109(6), 1863-75.
  75. Slugg RM, Light AR (1994 Jan 1). Spinal cord and trigeminal projections to the pontine parabrachial region in the rat as demonstrated with Phaseolus vulgaris leucoagglutinin. J Comp Neurol, 339(1), 49-61.
  76. Light, AR (). Sources of plasticity leading to chronic pain and opiod tolerance [commentary]. APS Journal, 2, 280-282.
  77. Light AR, Sedivec MJ, Casale EJ, Jones SL (1993). Physiological and morphological characteristics of spinal neurons projecting to the parabrachial region of the cat. Somatosens Mot Res, 10(3), 309-25.
  78. Alvarez FJ, Kavookjian AM, Light AR (1993 Mar 22). Ultrastructural morphology, synaptic relationships, and CGRP immunoreactivity of physiologically identified C-fiber terminals in the monkey spinal cord. J Comp Neurol, 329(4), 472-90.
  79. Alvarez FJ, Kavookjian AM, Light AR (1992 Aug). Synaptic interactions between GABA-immunoreactive profiles and the terminals of functionally defined myelinated nociceptors in the monkey and cat spinal cord. J Neurosci, 12(8), 2901-17.
  80. Bullitt E, Lee CL, Light AR, Willcockson H (1992 May 15). The effect of stimulus duration on noxious-stimulus induced c-fos expression in the rodent spinal cord. Brain Res, 580(1-2), 172-9.
  81. Jones SL, Light AR (1992 Aug 22). Serotoninergic medullary raphespinal projection to the lumbar spinal cord in the rat: a retrograde immunohistochemical study. J Comp Neurol, 322(4), 599-610.
  82. Wang S-F, Nelson C, Gross MT, Light AR (1992-01-01). The Effect of Transcutaneous Electric Nerve Stimulation on Somatosensory Evoked Potentionals and Subjective Pain. J Clin Electrophysiol, 4, 23-28.
  83. Casale EJ, Light AR (1991 Nov). The terminations of single, physiologically identified, somatosensory, corticospinal tract axons in the lumbar spinal cord of the cat. J Neurophysiol, 66(5), 1738-49.
  84. Jones SL, Light AR (1990 Jul 8). Termination patterns of serotoninergic medullary raphespinal fibers in the rat lumbar spinal cord: an anterograde immunohistochemical study. J Comp Neurol, 297(2), 267-82.
  85. Jones SL, Light AR (1990 Oct 22). Electrical stimulation in the medullary nucleus raphe magnus inhibits noxious heat-evoked fos protein-like immunoreactivity in the rat lumbar spinal cord. Brain Res, 530(2), 335-8.
  86. Jones SL, Sedivec MJ, Light AR (1990 Nov 5). Effects of iontophoresed opioids on physiologically characterized laminae I and II dorsal horn neurons in the cat spinal cord. Brain Res, 532(1-2), 160-74.
  87. Rethelyi M, Light AR, Perl ER (1989 Jun). Synaptic ultrastructure of functionally and morphologically characterized neurons of the superficial spinal dorsal horn of cat. J Neurosci, 9(6), 1846-63.
  88. Bullitt E, Light AR (1989 Aug 8). Intraspinal course of descending serotoninergic pathways innervating the rodent dorsal horn and lamina X. J Comp Neurol, 286(2), 231-42.
  89. Light AR, Kavookjian AM (1988 Jan 8). Morphology and ultrastructure of physiologically identified substantia gelatinosa (lamina II) neurons with axons that terminate in deeper dorsal horn laminae (III-V). J Comp Neurol, 267(2), 172-89.
  90. Casale EJ, Light AR, Rustioni A (1988 Dec 8). Direct projection of the corticospinal tract to the superficial laminae of the spinal cord in the rat. J Comp Neurol, 278(2), 275-86.
  91. Light AR, Casale EJ, Menetrey DM (1986 Sep). The effects of focal stimulation in nucleus raphe magnus and periaqueductal gray on intracellularly recorded neurons in spinal laminae I and II. J Neurophysiol, 56(3), 555-71.
  92. Fyffe RE, Cheema SS, Light AR, Rustioni A (1986 Nov). Intracellular staining study of the feline cuneate nucleus. II. Thalamic projecting neurons. J Neurophysiol, 56(5), 1284-96.
  93. Yen C-T, Blum PS, Light AR (1986-01-01). Raphe-Spinal Neurons: Convergence of Baroreceptor and Nociceptor Inputs and Their Morphology from Intracellular Staining. J Auton Nerv Syst, Suppl, 275-280.
  94. Light AR (1985 Apr 22). The spinal terminations of single, physiologically characterized axons originating in the pontomedullary raphe of the cat. J Comp Neurol, 234(4), 536-48.
  95. Light AR, Kavookjian AM (1985 Apr 22). The ultrastructure and synaptic connections of the spinal terminations from single, physiologically characterized axons descending in the dorsolateral funiculus from the midline, pontomedullary region. J Comp Neurol, 234(4), 549-60.
  96. Cheema S, Fyffe R, Light A, Rustioni A (1984 Jan 2). Arborizations of single corticofugal axons in the feline cuneate nucleus stained by iontophoretic injection of horseradish peroxidase. Brain Res, 290(1), 158-64.
  97. Ralston HJ 3rd, Light AR, Ralston DD, Perl ER (1984 Apr). Morphology and synaptic relationships of physiologically identified low-threshold dorsal root axons stained with intra-axonal horseradish peroxidase in the cat and monkey. J Neurophysiol, 51(4), 777-92.
  98. McKenna TM, Light AR, Whitsel BL (1984 May). Neurons with unusual response and receptive-field properties in upper laminae of cat SI cortex. J Neurophysiol, 51(5), 1055-76.
  99. Fyffe RE, Light AR (1984 May 23). The ultrastructure of group Ia afferent fiber synapses in the lumbosacral spinal cord of the cat. Brain Res, 300(2), 201-9.
  100. Light AR, Durkovic RG (1984 Sep). Features of laminar and somatotopic organization of lumbar spinal cord units receiving cutaneous inputs from hindlimb receptive fields. J Neurophysiol, 52(3), 449-58.
  101. Light AR, Kavookjian AM, Petrusz P (1983). The ultrastructure and synaptic connections of serotonin-immunoreactive terminals in spinal laminae I and II. Somatosens Res, 1(1), 33-50.
  102. Rethelyi M, Light AR, Perl ER (1982 Jun 1). Synaptic complexes formed by functionally defined primary afferent units with fine myelinated fibers. J Comp Neurol, 207(4), 381-93.
  103. Metz CB, Kavookjian AM, Light AR (1982-01-01). Techniques for HRP Intracellular Staining of Neural Elements for Light and Electron Microscopic Analyses. J Electrophysiol Technol, 9, 151-163.
  104. Konietzny F, Perl ER, Trevino D, Light A, Hensel H (1981). Sensory experiences in man evoked by intraneural electrical stimulation of intact cutaneous afferent fibers. Exp Brain Res, 42(2), 219-22.
  105. Jochem WJ, Light AR, Smith D (1981 Feb). A high voltage electrometer for recording and iontophoresis with fine-tipped, high resistance microelectrodes. J Neurosci Methods, 3(3), 261-9.
  106. Light AR, Perl ER (1979 Jul 15). Spinal termination of functionally identified primary afferent neurons with slowly conducting myelinated fibers. J Comp Neurol, 186(2), 133-50.
  107. Light AR, Perl ER (1979 Jul 15). Reexamination of the dorsal root projection to the spinal dorsal horn including observations on the differential termination of coarse and fine fibers. J Comp Neurol, 186(2), 117-31.
  108. Light AR, Trevino DL, Perl ER (1979 Jul 15). Morphological features of functionally defined neurons in the marginal zone and substantia gelatinosa of the spinal dorsal horn. J Comp Neurol, 186(2), 151-71.
  109. Light AR, Metz CB (1978 Jun 1). The morphology of the spinal cord efferent and afferent neurons contributing to the ventral roots of the cat. J Comp Neurol, 179(3), 501-15.
  110. Light AR, Perl ER (1977-01-01). Differential Termination of Large-Diameter and Small-Diameter Primary Afferent Fibers in the Spinal Dorsal Gray Matter as Indicated by Labeling with Horseradish Peroxidase. Neurosci Lett, 6, 59-63.
  111. Light AR, Durkovic RG (1977-01-01). US Intensity and Blood Pressure Effects on Classical Conditioning and Sensitization in Spinal Cats. Physiol Psychol, 5, 81-88.
  112. Light AR, Durkovic RG (1976 Dec). Horseradish peroxidase: an improvement in intracellular staining of single, electrophysiologically characterized neurons. Exp Neurol, 53(3), 847-53.
  113. Durkovic RG, Light AR (1975 Nov 14). Spinal conditioning: unconditioned stimulus intensity requirement. Brain Res, 98(2), 364-8.

Review

  1. Light KC, White AT, Tadler S, Iacob E, Light AR (). Genetics and Gene Expression Involving Stress and Distress Pathways in Fibromyalgia With and Without Comorbid Chronic Fatigue Syndrome. [Review]. Genetics.
  2. Fu KY, Cao Y, Light AR (). Responses to Drs. Bereiter et al. regarding comments on Experimental occlusal interference induces long-term masticatory muscle hyperalgesia in rats by Cao et al. [Review]. Pain.
  3. Light AR, Perl ER (2003 Jun 23). Unmyelinated afferent fibers are not only for pain anymore. [Review]. J Comp Neurol, 461(2), 137-9.
  4. Kruger L, Light AR, Schweizer FE (2003 Mar). Axonal terminals of sensory neurons and their morphological diversity. [Review]. J Neurocytol, 32(3), 205-16.
  5. Vierck CJ Jr, Light AR (2000). Allodynia and hyperalgesia within dermatomes caudal to a spinal cord injury in primates and rodents. [Review]. Prog Brain Res, 129, 411-28.
  6. Light AR (1988). Normal anatomy and physiology of the spinal cord dorsal horn. [Review]. Appl Neurophysiol, 51(2-5), 78-88.
  7. Light AR (). New methodologies/future directions. In: Neurology and Neurobiology, Effects of Injury on Trigeminal and Spinal Somatosensory Systems. [Review]. Neurology and Neurobiology, 30, 467-473.
  8. Light AR (1982-01-01). Review of High Voltage Electrometer. [Review]. J Electrophysiol Technol, 9, 89-90.

Book

  1. Kruger L, Light AR (). Translational Pain Research From Mouse to Man: Series Frontiers in Neuroscience. New York: CRC Press.
  2. Light AR, Shults RC, Jones SL (1992-01-01). The Initial Processing of Pain and its Descending Control: Spinal and Trigeminal Systems. Basel: S. Karger AG.

Book Chapter

  1. Light AR, Vierck CJ, Light KC (2010). Myalgia and Fatigue: Translation from Mouse Sensory Neurons to Fibromyalgia and Chronic Fatigue SyndromesBTI - Translational Pain Research: From Mouse to ManCP - Chapter 11. Boca Raton, FL.
  2. Light AR, Lee S (). Spinal Cord Physiology of Nociception. In The Senses: A Comprehensive Reference (5, pp. 311-330). San Diego: Academic Press.
  3. Spigelman I, Gold MS, Light AR (2001-01-01). Electrophysiological Recording Techniques in Pain Research. In Kruger L (Ed.), Methods in Pain Research. Boca Raton, FL: CRC Press.
  4. Light AR, Perl ER (1991-01-01). Peripheral Sensory Systems. In Dyck, Thomas, Lambert, Bunge (Eds.), Peripheral Neuropathy (2nd). Philadelphia, PA: Saunders.
  5. Light AR, Kavookjian AM (1989-01-01). Electron Microscopic Localization of Peptide-Like Immunoreactivity in Labeled Dorsal Root: Terminals in the Spinal Substantia Gelatinosa. In Cervero F, Bennett GJ, Headley PM (Eds.), Processing of Sensory Information in the Superficial Dorsal Horn of the Spinal Chord. New York, NY: Plenum Press.
  6. Light AR, Casale E, Sedivec M (1987-01-01). The Physiology and Anatomy of Spinal Laminae I and II Neurons Antidromically Activated by Stimulation in the Parabrachial Region of the Midbrain and Pons. In Schmidt RF, Schaible HG, Vahle-Hinz (Eds.), Fine Afferent Nerve Fibers and Pain (pp. 349-356). Weinheim: VCH Verlagsgesellschaft.
  7. Rethelyi M, Light AR, Perl ER (1985-01-01). Synaptic Contacts on Physiologically Defined Neurons of the Superficial Dorsal Horn. In Fields H (Ed.), Advances in Pain Research and Therapy (9, pp. 139-147). New York, NY: Raven Press.
  8. Fyffe REW, Cheema SS, Light AR, Rustioni A (1985-01-01). The Organization of Neurons and Afferent Fibers in the Cat Cuneate Nucleus. In Liss AR (Ed.), Development, Organization, and Processing in Somatosensory Pathways (pp. 163-173).
  9. Light AR (1983-01-01). Spinal Projections of Physiologically Identified Axons from the Rostral Medulla of Cats. In Bonica JJ, Lindblom U, Iggo A (Eds.), Advances in Pain Research and Therapy (5, pp. 373-379). New York, NY: Raven Press.
  10. Rethelyi M, Light AR, Perl ER (1983-01-01). Synapses Made by Nociceptive Laminae I and II Neurons. In Bonica JJ, Linblom U, Iggo A (Eds.), Advances in Pain Research and Therapy (5, pp. 111-118). New York, NY: Raven Press.
  11. Manse S, Light AR, Perl ER (1981-01-01). Spinal Terminations of Subcutaneous High-Threshold Mechanoreceptors. In Brown AG, Rethelyi M (Eds.), Spinal Chord Sensation (pp. 79-85). Edinburgh: Scottish Academic Press.
  12. Light AR, Rethelyi M, Perl ER (1981-01-01). Ultrastructure of Functionally Identified Neurones in the Marginal Zone and the Substantia Gelatinosa. In Brown AG, Rethelyi M (Eds.), Spinal Cord Sensation (pp. 97-102). Edinburgh: Scottish Academic Press.

Conference Proceedings

  1. Durkovic R, Hoover J, Light AR, Taylor-Blake B (1995-01-01). Cutaneous Flexion Reflexes: Neuroanatomical Studies. Kyoto: International Brain Research Organization World Congress, 334.
  2. Hulse-Neufeld J, Light AR, Taylor-Blake B, Breen L (1994-01-01). Nociceptive Behavior and Spinal Cord C-Fos in Rats Subjected to Chronic Intermittent Stimuli. Abstr from the American Pain Society 13th Annual Meeting, A-115.
  3. Schneider SP, Light AR (1994-06-01). Nucleotide 5'-Triphosphates are Necessary for Mu-Opioid Receptor-Activated Postsynaptic Responses in Substantia Gelatinosa Neurons. Proceedings of International Narcotics Research Conference In: Regulatory Peptides.
  4. Alvarez FJ, Kavookjian AM, Light AR (1992-01-01). Nociceptive Primary Afferents are Controlled Both Pre- and Postsynaptically by GABA-Immunoreactive Profiles. Montreal: Abstracts from the 3rd International Brain Research Organization World Congress, 193.

Book Review

  1. Light AR (). "The spinoparabrachial tract" and "Cordotomy as a model of spinal cord injury". [Review of the book ]. Encyclopedia of Pain.
  2. Light AR (1987-01-01). Spinal Afferent Processing. [Review of the book ]. The Quarterly Review of Biology.
  3. Light AR (1985-01-01). The Neurobiology of Pain. [Review of the book ]. Trends in Neuroscience.

Letter

  1. Light AR, Perl ER (1977 Oct). Differential termination of large-diameter and small-diameter primary afferent fibers in the spinal dorsal gray matter as indicated by labeling with horseradish peroxidase [Letter to the editor]. Neurosci Lett, 6(1), 59-63.

Abstract

  1. Walder RY, Rasmussen LA, Rainier JD, Light AR, Wemmie JA, Sluka KA (). ASIC 1 and ASIC 3 play different roles in the development of hyperalgesia following inflammatory muscle injury [Abstract]. Program No. 174.5/NN5. Neuroscience Meeting Planner, Society for Neuroscience.
  2. Light AR, Hughen RW, Zhang J, White A, Light KC, Jensen BT, Fitschen KL (). Molecular receptors for pH found on sensory neurons are also found on mouse and human leukocytes and increase 8-48 hours post-exercise in both control subjects and fibromyalgia and chronic fatigue patients [Abstract]. Society for Neuroscience Program No. 510:3.
  3. Hughen RW, Light AR, Zhang J, Thambyah TT, Fitschen KL (). Combinations of ASIC, P2X and TRPV1 receptors on muscle afferent neurons detect physiological pH levels when lactate and ATP are also present [Abstract]. Society for Neuroscience Program No. 510.2.
  4. Light AR, Hughen RW, Zhang J (). Dorsal root ganglion (DRGs) responding to combinations of lowered pH, increased lactate, and ATP [Abstract]. Society for Neuroscience Program No. 246.19.
  5. Light AR, Guthrie P, Hughen R (). Purinergic Receptors activating mouse microglia in culture [Abstract]. Society for Neuroscience Program No. 974.6.
  6. Light A, Belmonte C, Byers, MR, Kaufman M, Bushnell M (). C-Fibers are not just for pain anymore [Abstract]. Program No. 128.
  7. Kruger L, Kavookjian AM, Kumazawa T, Light AR, Mizumura K (2003-01-01). Electron Microscopy of Nociceptive Testicular Free Nerve Endings [Abstract]. Soc Neurosci Abstr, 29, 26.
  8. Heck WL, Taylor-Blake B, Willcockson HH, Light AR (2002-01-01). Fos Expression in the Lumbar Spinal cord Dorsal Horn Following Colchinicines Injection into the Rat Hindpaw [Abstract]. Soc Neurosci Abstr, 28.
  9. Heck WL, Willcockson HH, Light AR (2001-01-01). Activation of Spinal Cord Microglia Following Injection of Colchinicines into the Rat Hindpaw [Abstract]. Soc Neurosci Abstr, 27.
  10. Fu K-Y, Ma XC, Light AR, Maixner W (2001-01-01). TNF Alpha and FAS Expression in Spinal Cord Dorsal Horn Following Formalin Injection into the Rat Hindpaw [Abstract]. Soc Neurosci Abstr, 27.
  11. Wu Y, Willcockson HH, Maixner W, Light AR (2001-01-01). Role of Spinal Cord Microglia in Formalin Induced Hyperalgesia in Rat [Abstract]. Soc Neurosci Abstr, 27.
  12. Light AR, Knappenberger J, Kater SB, Guthrie PB (2000-01-01). Astrocyte Calcium Waves: Potential Pathology Related Consequences [Abstract]. Soc Neurosci Abstr, 26, 1895.
  13. Eckert WA III, McNaughton KK, Light AR (2000-01-01). Morphology and Mu-Opioid Evoked Hyperpolarization of Rat Spinal Substantia Gelatinosa Neurons [Abstract]. Soc Neurosci Abstr, 26, 1139.
  14. Ahn DK, Maixner W, Doutova EA, McNaughton K, Light AR, Narhi M (2000-01-01). Response Properties of Trigeminal Tooth Pulp Neurons to Noxious Heat and Cold Stimulation in the Ferret [Abstract]. Soc Neurosci Abstr, 26, 1138.
  15. Durkovic RG, Light AR (2000-01-01). Spinal Cord Neurons Receiving Direct Cutaneous Inputs: Comparisons Between Neurophysiological and Neuroanatomical Results from Cat [Abstract]. Soc Neurosci Abstr, 26, 1138.
  16. Doutova EA, McNaughton K, Gonzalez Robaina P, Ahn DK, Light AR, Goy M, Maixner W (1999-01-01). Trigeminal Expression of Prodynorphin mRNA in Response to LPS-Induced Pulpitis in the Ferret [Abstract]. Soc Neurosci Abstr, 25, 928.
  17. Eckert WA, Light AR (1999-01-01). Mu-Opioid Receptor Activation Hyperpolarizes More Spinal Lamina II Neurons than Does Kappa or Delta Activation [Abstract]. Soc Neurosci Abstr, 25, 926.
  18. Chaisin S, Light AR, Narhi M, Maixner W (1998-01-01). The Effects of Noxious Thermal Conditioning on the Jaw-Opening Reflex and Trigeminal Fos Expression in the Ferret [Abstract]. Soc Neurosci Abstr, 24, 386.
  19. Fu K, Light AR, Maixner W (1998-01-01). Long-Lasting Inflammation and Hyperalgesia Evoked by Subcutaneous Formalin Injection: Associated with Spinal Microglial Activation [Abstract]. Soc Neurosci Abstr, 24, 385.
  20. Chaisin S, Light AR, Narhi M, Maixner W (1998-01-01). Trigeminal Fos Expression Following Selective Activation and Modulation of Pulpal Nociceptors [Abstract]. J Dent Res, 77 (Special Issue), 291.
  21. Fu K, Light AR, Maixner W (1998-01-01). Microglial Reactions After Subcutaneous Formalin Injection into the Rat's Hind Paw [Abstract]. J Dent Res, 77 (Special Issue), 292.
  22. Doutova EA, Chaisin S, McNaughton K, Light AR, Goy M, Maixner W (1998-01-01). Expression of Prodynorphin mRNA in the Ferret Trigeminal Nuclear Complex Following Noxious Thermal Tooth Stimulation [Abstract]. Soc Neurosci Abstr, 24, 394.
  23. Doutova EA, Li Z, Light AR, Goy M, Maixner W (1997-01-01). Partial Sequence and Comparison of Rat and Ferret Prodynorphin [Abstract]. Soc Neurosci Abstr, 23, 90.
  24. Chaisin S, Maixner W, Narhi M, Taylor-Blake B, Light AR (1997-01-01). Fos-Like Immunoreactivity (Fos-LI) in the Spinal Trigeminal Nucleus Following Stimulation of Myelinated (A-Delta) or Non-Myelinated (C) Afferents from the Ferret's Upper Maxillary Canine [Abstract]. Soc Neurosci Abstr, 23, 2351.
  25. Eckert WA, McNaughton KK, Light AR (1997-01-01). Membrane Responses of Rat Spinal Laminae I & II Neurons Recorded In Vitro Evoked by Mu, Kappa, & Delta Opioid Receptor Agonists [Abstract]. Soc Neurosci Abstr, 23, 678.
  26. Light AR, Willcockson HH, Schneider SP (1997-01-01). Effects of Mu-Opioid Agonists on Rat Spinal Laminae I and II Neurons Recorded in Whole-Cell, Tight Seal Mode In Vivo [Abstract]. Soc Neurosci Abstr, 23, 1022.
  27. Chaisin S, Maixner W, Taylor-Blake B, Light AR (1997-01-01). Fos Expression in Trigeminal Nucleus Following Tooth Stimulation in Ferrets (IADR Abstract) [Abstract]. J Dent Res, 76, 294.
  28. Chaisin S, Heyeraas KJ, Light AR, Maixner W (1996-01-01). C-Fos Expression in Trigeminal Nucleus Following Either Skin Incision or Mustard Oil Application to Maxillary Skin [Abstract]. Soc Neurosci Abstr, 22, 862.
  29. Durkovic RG, Hoover JE, Light AR (1996-01-01). Anatomy of the Disynaptic Flexion Reflex Circuitry in Cat Spinal Cord [Abstract]. Soc Neurosci Abstr, 22, 1835.
  30. Vincler M, Maixner W, Essick G, Light AR (1996-01-01). Estrous Cycle and Ovarectomy Alter Nociceptive Behaviors and Morphine-Induced Analgesia in the Formalin Test and a Novel Electrical Stimulation Paradigm [Abstract]. Soc Neurosci Abstr, 22, 1367.
  31. Light AR, Willcockson HH (1996-01-01). In Vivo Whole-Cell Recordings form Spinal Substantia Gelatinos (Lamina II) Neurons of Adult Rats [Abstract]. Soc Neurosci Abstr, 22, 861.
  32. Koerber HR, Mirnics K, Kavookjian AM, Light AR (1995-01-01). Ultrastructural Analysis of Ectopic Synaptic Boutons Supported by Regenerated Afferent Fibers [Abstract]. Soc Neurosci Abstr, 21(1), 566.
  33. Vincler M, Maixner W, Vierck CJ, Light AR (1995-01-01). Morphine Sensitivity of Spinal- and Supraspinal-Mediated Nociceptive Responses Using a Novel Electrical Stimulation Paradigm [Abstract]. Soc Neurosci Abstr, 21(2), 1168.
  34. Alvarez FJ, Taylor-Blake B, Fyffe REW, De Blas AL, Light AR (1995-01-01). Distribution of Immunoreactivity for the Beta-2 and Beta-3 Subunits of the GABA Receptor in the Mammalian Spinal Cord [Abstract]. Soc Neurosci Abstr, 21(1), 380.
  35. Koerber HR, Mirnics K, Kavookjian AM, Light AR (1995-01-01). Ultrastructural Analysis of Ectopic Synaptic Boutons Supported by Regenerated Afferent Fibers [Abstract]. Soc Neurosci Abstr.
  36. Vincler M, Maixner W, Vierck CJ, Light AR (1995-01-01). Morphine Sensitivity of Spinal- and Supraspinal-Mediated Nociceptive Responses Using a Novel Electrical Stimulation Paradigm [Abstract]. Soc Neurosci Abstr.
  37. Li Z, Taylor-Blake B, Light AR, Goy MF (1995-01-01). Immunocytochemical Localization of Guanylin, An Endogenous Ligand for C-Type Guanylate Clclase [Abstract]. Am Gastroenterol Assoc Abstr in Gastroenterol, 108, A986.
  38. Schneider SP, Light AR (1994-01-01). Involvement of Guanosine 5'-Triphosphate in Mu-Opioid Receptor-Activated Postsynaptic Responses in Substantia Gelatinosa Neurons [Abstract]. Soc Neurosci Abstr, 20(2), 1730.
  39. Bove GM, Light AR (1993-01-01). CGRP-Like Immunoreactivity of Fine Afferents Innervating Peripheral Nerve Sheaths [Abstract]. Soc Neurosci Abstr, 19, 324.
  40. Bove GM, Light AR (1992-01-01). Paraspinal Nociceptive Primary Afferents [Abstract]. Soc Neurosci Abstr, 18, 384.
  41. Robinson GA, Light AR (1992-01-01). Axotomy-Induced Expression of Immediate Early Genes in Rat Retinal Ganglion Cells [Abstract]. Soc Neurosci Abstr, 18, 1312.
  42. Slugg RM, Light AR (1991-01-01). Efferent Projections from the Lateral Parabrachial Nucleus as Demonstrated by PHA-L [Abstract]. Soc Neurosci Abstr, 17, 1204.
  43. Lee CL, Willcockson HH, Vierck CJ, Light AR (1991-01-01). The Relationship of an Aversive Operant Behavior to the Expression of C-Fos in the Lumbar Spinal Cord of the Rat [Abstract]. Soc Neurosci Abstr, 17, 1009.
  44. Alvarez FJ, Kavookjian AM, Light AR (1991-01-01). Neuropeptide Content and Interactions with GABA-Immunoreactive Profiles of Physiologically Identified Lamina I and II Monkey Primary Afferent Terminals [Abstract]. Soc Neurosci Abstr, 17, 1003.
  45. Slugg RM, Light AR (1990-01-01). Physiology and morphology of Nocireceptive and Thermoreceptive Parabrachial Neurons [Abstract]. Soc Neurosci Abstr, 16, 1144.
  46. Willcockson HH, Light AR, Bullitt E, Vierck CJ (1990-01-01). FOS Oncoprotein-Like Immunoreactivity Evoked by Noxious Heat and Electrical Stimulation in the Anesthetized Rat and Monkey [Abstract]. Soc Neurosci Abstr, 16, 703.
  47. Jones SL, Light AR (1990-01-01). Re-Examination of the Seotonergic Raphespinal Projection in the Rat: A Retrograde Immunohistochemical Study [Abstract]. Soc Neurosci Abstr, 16, 98.
  48. Shults RC, Kavookjian AM, Light AR (1989-01-01). Ultrastructure of Tooth Pulp and HTM-Tongue Terminations in Trigeminal Interstitial Nucleus of the Cat [Abstract]. Soc Neurosci Abstr, 15, 1266.
  49. Slugg RM, Light AR (1989-01-01). Terminations of Lamina I Spinoparabrachial Projections in the Rat [Abstract]. Soc Neurosci Abstr, 15, 1189.
  50. Jones SL, Sedivec MJ, Light AR (1989-01-01). Effects of Opioids on Physiologically Characterized Superficial Dorsal Horn Neurons in the Cat [Abstract]. Soc Neurosci Abstr, 15, 181.
  51. Light AR, Jones SL (1989-01-01). Stimulation of Nucleus Raphe Magnus Reduces the Number of Lumbar Spinal Cord Neurons Demonstrating Fos Oncoprotein-Like Immunoreactivity Following Noxious Heat Stimulation of the Foot in the Rat [Abstract]. Soc Neurosci Abstr, 15, 181.
  52. Jones SL, Light AR (1988-01-01). Laminar Distribution of Raphespinal Fibers in the Rat Lumbar Dorsal Horn Demonstrating Serotonin-Like Immunoreactivity [Abstract]. Soc Neurosci Abstr, 14, 852.
  53. Casale EJ, Light AR (1987-01-01). Direct Projection of the Corticospinal Tract to the Superficial Laminae in the Rat Using the Anterograde Transport of Phaseolus Vulgaris-Leucoagglutinin [Abstract]. Soc Neurosci Abstr, 13, 580.
  54. Shults RC, Light AR (1987-01-01). Intracellularly Stained Cells and Afferent Fibers in Nucleus Caudalis and the Spinal Trigeminal Tract [Abstract]. Soc Neurosci Abstr, 13, 116.
  55. Sedivec MJ, Dunnigan MA, Kavookjian AM, Light AR (1987-01-01). Local Axon Collaterals from Spinal Laminae I and II Neurons Which Project to the Brain Stem [Abstract]. Soc Neurosci Abstr, 13, 113.
  56. Casale EJ, Kavookjian AM, Light AR (1985-01-01). Morphology and Ultrastructure of Terminations from Single Cortcospinal Tract Axons Arising from Sensorimotor Cortex in the Cat [Abstract]. Soc Neurosci Abstr, 11, 904.
  57. Shults RC, Light AR, Donaghy S (1985-01-01). Interstitial Nucleus of the Spinal Trigeminal Tract: A Specific Nociceptive Relay for Oral and Perioral Structures? [Abstract]. Soc Neurosci Abstr, 11, 578.
  58. Light AR, Casale EJ, Menetrey D (1985-01-01). Spinal Cord Laminae I and II Neurons Which Project to the Contralateral Pontine Reticular Formation in the Cat [Abstract]. Soc Neurosci Abstr, 11, 411.
  59. Casale EJ, Light AR, Rustioni A (1984-01-01). Spinal Termination of Fibers Arising from the Primary Sensorimotor Cortex of Rats [Abstract]. Soc Neurosci Abstr, 10, 900.
  60. Light AR, Kavookjian AM (1984-01-01). Substantia Gelatinosa Neurons with axons Projecting to Other Dorsal Horn Laminae [Abstract]. Soc Neurosci Abstr, 10, 489.
  61. Light AR (1983-01-01). Postsynaptic Effects in Spinal Lamina I and II Neurons Produced by Stimulating Midline Medulla and Pons [Abstract]. Soc Neurosci Abstr, 9, 2.
  62. Light AR, Kavookjian A (1982-01-01). Ultrastructure of Spinal Cord Terminations of Physiologically Identified axons Descending form Midline Medulla and Pons [Abstract]. Soc Neurosci Abstr, 8, 805.
  63. Rethelyi M, Light AR, Perl ER (1981-01-01). Synapses Made by Nociceptive Laminae I and II Neurones [Abstract]. Pain, Supplement a, S127.
  64. McKenna TM, Light AR, Whitsel BL (1981-01-01). Unusual Receptive Field and Response Properties of Neurons in the Upper Layers of the S-I Cortex of the Cat [Abstract]. Soc Neurosci Abstr, 7, 835.
  65. Light AR (1981-01-01). Spinal Projections of Physiologically Identified Axons form the Rostral Medulla of Cats [Abstract]. Pain, Supplement 1, S103.
  66. Fyffe REW, Light AR, Rustioni A (1981-01-01). Cuneo-Thalamic Neurons in the Cat: An Intracellular HRP Study [Abstract]. J Physiol (Lond), 322, 29-30P.
  67. Basbaum AI, Light AR, Bennett GJ, Galzer EJ, Yamamoto-Yoshida M (1981-01-01). The Dorsal Horn: A Profound and a Superficial Analysis [Abstract]. Soc Neurosci Abstr, 7, 1.
  68. Mense S, Light AR, Perl ER (). Spinal terminations of subcutaneous, high threshold mechanoreceptors [Abstract]. International Congress of Physiological Sciences.
  69. Ralston HJ III, Light AR, Perl ER, Ralston DD (1980-01-01). The Projection of Dorsal Root Fibers to the Deep Dorsal Horn of the Macaque Spinal Cord, Examined by Degeneration, Autoradiographic, and Intraaxonal Labeling Techniques [Abstract]. Anat Rec, 196, 152A.
  70. Light AR, Rethelyi M (1980-01-01). Second Order Neurones of the Marginal Zone and Substantia Gelatinosa [Abstract]. International Congress of Physiological Sciences. Satellite Symposium on Sensory Processing in the Dorsal Horn, Keszthely.
  71. Light AR (). Workshop on the intracellular staining of neural elements in mammals, organized by D. Egger [Abstract]. Winter Conference on Brain Research, Sun Valley, Idaho.
  72. Rethelyi M, Light AR, Perl ER (1979-01-01). Ultrastructure of Synaptic Terminations of Functionally Identified Fine Myelinated Afferent Fibers [Abstract]. Soc Neurosci Abstr.
  73. Light AR, Mense S, Perl ER (1979-01-01). Spinal Terminations of Subcutaneous High Threshold Mechanoreceptors [Abstract]. Soc Neurosci Abstr, 5, 725.
  74. Ralston HJ, Light AR, Perl ER (1978-01-01). Electron Microscopic Observations on the Spinal Termination of Physiologically Identified Dorsal Root Axons [Abstract]. Soc Neurosci Abstr, 4, 570.
  75. Light AR, Trevino DL, Perl ER (1978-01-01). Morphology of Physiologically Identified Neurons in the Spinal Marginal Zone and Substantia Gelatinosa [Abstract]. Soc Neurosci Abstr, 4, 567.
  76. Hanker JS, Yates P, Metz C, Carson K, Light AR, Rustioni A (1977-01-01). A New Specific Sensitive and Noncarcinogenic Reagent for the Demonstration of Horseradish Peroxidase (HRP) [Abstract]. Soc Neurosci Abstr, 3, 30.
  77. Light AR, Perl ER (1977-01-01). Central Termination of Identified Cutaneous Afferent Units with Fine Myelinated Fibers [Abstract]. Soc Neurosci Abstr, 3, 486.
  78. Light AR, Durkovic RG (1976-01-01). Somatotopic and Lamina Organization of Spinal Interneurons Receiving Cutaneous Inputs from Cat Hindlimb [Abstract]. Soc Neurosci Abstr, 2, 916.
  79. Light AR, Durkovic RG (1975-01-01). Effects of Blood Pressure and US Intensity on Classical Conditioning and Sensitization in the Spinal Cat [Abstract]. Soc Neurosci Abstr, 1, 521.
  80. Light AR, Durkovic RG (1974-01-01). Effect of Unconditioned Stimulus Intensity on Spinal Conditioning [Abstract]. Soc Neurosci Abstr, 403.

Other

  1. Tadler S, Weeks H, Smith KW, Bushnell L, Iacob E, Light AR, Cahalan MK, Light KC (). "Antidepressant and neurocognitive effects of isoflurane versus ect in medication resistant patients". Program No. 665.07/X18 Neuroscience Meeting Planner. Society for Neuroscience. New Orleans.
  2. Vanhaitsma TA, Light AR, Light KC, Hughen RW, Yenchik S, White AR (). "Effect of 40k Time Trial Performance During Thermoneutral and Heat-Stressed Conditions on Metabolite-Detecting Gene Expression and Fatigue". ACSM Poster.
  3. Vanhaitsma TA, Light AR, Light KC, Hughen RW, White AT (). "Metabolite-detecting and adrenergic gene expression after 40k TT performance during ambient and heat-stressed conditions". Program #7824 Experimental Biology Meeting. San Diego.
  4. Iacob E, Light AR, Hughen RW, Tadler S, Light KC (). "Gene Expression biomarkers for Major Depressive Disorder before and after ECT treatment". Neuroscience Meeting Planner. Society for Neuroscience. Washington DC.
  5. Pollak KA, Light AR, Swenson J, Jo D, Hughen RW, Vanhaitsma TA, Beilke JL, White AT, Tadler S, Light KC (). Metabolites that evoke fatigue and pain sensations in human muscles. Neuroscience Meeting Planner. Society for Neuroscience. San Diego.
  6. Light AR, Hughen RW, White AT, Jensen BT, Michael T, Larson C, Vanhaitsma T, Light KC (). Chronic Fatigue Syndrome (CFS) patients but not control subjects increase mRNA for sensory, adrenergic and immune genes in leukocytes following moderate exercise. Program No. 76.5/Y4 Neuroscience Meeting Planner. Society for Neuroscience. Chicago.
  7. Light AR, White A, Hughen R, Bateman L, Light KC (). Adrenergic and Sensory Receptor Expression on Leukocytes Increases After Moderate Exercise in Chronic Fatigue and Fibromyalgia. 9th Biennial IACFS/ME Conference.
  8. Radhakrishnan R, Hughen RW, Light AR (). Involvement of ASIC and P2X channels in ischemic pain. Program No. 415.4 Neuroscience Meeting Planner. Society for Neuroscience. Washington DC.
  9. Light AR, Hughen RW, Zhang J (). Increases in receptor mRNA in mouse dorsal root ganglion (DRG) neurons following carrageenan induced inflammation of mouse hindlimb muscle. Program No. 174.16/NN16 Neuroscience Meeting Planner. Society for Neuroscience. Washington DC.
  10. Light AR (). Recent research supporting the existence of specific neural substrates for nociception in the spinal cord and trigeminal nuclei. International Union of Physiological Sciences, XXX International Congress. Vancouver, B.C., Canada.