David Krizaj, PhD

Research Interests

  • Glaucoma
  • Mechanisms of Calcium Homeostasis
  • Diabetic Retinopathy
  • Vision
  • Neuron-Glia Interaction
  • TRPV1
  • Astrocytes
  • Synaptic Transmission
  • Retina
  • Retinal Degeneration and Cell Biology
  • Functional Magnetic Resonance Imaging (fMRI)
  • Calcium Channel Blockers
  • Cellular mechanisms of neurotoxicity and the role calcium plays in neuropathological disorders

Languages

  • English

Academic Information

  • Departments: Ophthalmology/Visual Sciences - Professor

Education History

Type School Degree
Postdoctoral Fellowship University of California San Francisco
Physiology and Ophthalmology
Postdoctoral Fellow
Doctoral Training New York University
Physiology and Biophysics
Ph.D.
Graduate Training New York University
Physiology and Biophysics
M.S.
Graduate Training University of Ljubljana, School of Medicine
Biophysics
Undergraduate University of Ljublijana
Molecular Biology and Animal Physiology
B.S.

Global Impact

Education History

Type School Degree Country
Graduate Training University of Ljubljana, School of Medicine
Biophysics
Slovenia
Undergraduate University of Ljublijana
Molecular Biology and Animal Physiology
B.S. Slovenia

Selected Publications

Journal Article

  1. Lakk M, Yarishkin O, Baumann JM, Iuso A, Krizaj D (2017 Dec).

    Cholesterol regulates polymodal sensory transduction in Muller glia.

    . Glia, 65(12), 2038-2050.
  2. Jo AO, Noel JM, Lakk M, Yarishkin O, Ryskamp DA, Shibasaki K, McCall MA, Krizaj D (2017 Oct 15). Mouse retinal ganglion cell signalling is dynamically modulated through parallel anterograde activation of cannabinoid and vanilloid pathways. J Physiol, 595(20), 6499-6516.
  3. Phuong TTT, Redmon SN, Yarishkin O, Winter JM, Li DY, Krizaj D (2017 Sep 26). Calcium influx through TRPV4 channels modulates the adherens contacts between retinal microvascular endothelial cells.LID - 10.1113/JP275052 [doi]. (Epub ahead of print) J Physiol.
  4. Butler MR, Ma H, Yang F, Belcher J, Le YZ, Mikoshiba K, Biel M, Michalakis S, Iuso A, Krizaj D, Ding XQ (2017 Jul 07). Endoplasmic reticulum (ER) Ca2+-channel activity contributes to ER stress and cone death in cyclic nucleotide-gated channel deficiency. J Biol Chem, 292(27), 11189-11205.
  5. Toft-Bertelsen TL, Krizaj D, MacAulay N (2017 Jun 01). When size matters: transient receptor potential vanilloid 4 channel as a volume-sensor rather than an osmo-sensor. J Physiol, 595(11), 3287-3302.
  6. Phuong TT, Yarishkin O, Krizaj D (2016 Sep 02). Subcellular propagation of calcium waves in Muller glia does not require autocrine/paracrine purinergic signaling. Channels (Austin), 10(5), 421-427.
  7. Ryskamp DA, Frye AM, Phuong TT, Yarishkin O, Jo AO, Xu Y, Lakk M, Iuso A, Redmon SN, Ambati B, Hageman G, Prestwich GD, Torrejon KY, Krizaj D (2016 Aug 11). TRPV4 regulates calcium homeostasis, cytoskeletal remodeling, conventional outflow and intraocular pressure in the mammalian eye. Sci Rep, 6, 30583.
  8. Jo AO, Lakk M, Frye AM, Phuong TT, Redmon SN, Roberts R, Berkowitz BA, Yarishkin O, Krizaj D (2016 Apr 05). Differential volume regulation and calcium signaling in two ciliary body cell types is subserved by TRPV4 channels. Proc Natl Acad Sci U S A, 113(14), 3885-90.
  9. Molnar T, Yarishkin O, Iuso A, Barabas P, Jones B, Marc RE, Phuong TT, Krizaj D (2016 Mar 16). Store-Operated Calcium Entry in Muller Glia Is Controlled by Synergistic Activation of TRPC and Orai Channels. J Neurosci, 36(11), 3184-98.
  10. Iuso A, Krizaj D (2016). TRPV4-AQP4 interactions 'turbocharge' astroglial sensitivity to small osmotic gradients. Channels (Austin), 10(3), 172-4.
  11. Krizaj D (2016). Polymodal Sensory Integration in Retinal Ganglion Cells. Adv Exp Med Biol, 854, 693-8.
  12. Barabas P, Gorusupudi A, Bernstein PS, Krizaj D (2016). Mouse Models of Stargardt 3 Dominant Macular Degeneration. Adv Exp Med Biol, 854, 137-43.
  13. Cahoon JM, Rai RR, Carroll LS, Uehara H, Zhang X, ONeil CL, Medina RJ, Das SK, Muddana SK, Olson PR, Nielson S, Walker K, Flood MM, Messenger WB, Archer BJ, Barabas P, Krizaj D, Gibson CC, Li DY, Koh GY, Gao G, Stitt AW, Ambati BK (2015 Dec). Intravitreal AAV2.COMP-Ang1 Prevents Neurovascular Degeneration in a Murine Model of Diabetic Retinopathy. Diabetes, 64(12), 4247-59.
  14. Jo AO, Ryskamp DA, Phuong TT, Verkman AS, Yarishkin O, MacAulay N, Krizaj D (2015 Sep 30). TRPV4 and AQP4 Channels Synergistically Regulate Cell Volume and Calcium Homeostasis in Retinal Muller Glia. J Neurosci, 35(39), 13525-37.
  15. Ryskamp DA, Iuso A, Krizaj D (2015). TRPV4 links inflammatory signaling and neuroglial swelling. Channels (Austin), 9(2), 70-2.
  16. Ryskamp DA, Jo AO, Frye AM, Vazquez-Chona F, MacAulay N, Thoreson WB, Krizaj D (2014 Nov 19). Swelling and eicosanoid metabolites differentially gate TRPV4 channels in retinal neurons and glia. J Neurosci, 34(47), 15689-700.
  17. Deering-Rice CE, Mitchell VK, Romero EG, Abdel Aziz MH, Ryskamp DA, Krizaj D, Gopal VR, Reilly CA (2014 Oct). Drofenine: A 2-APB Analogue with Greater Selectivity for Human TRPV3. Pharmacol Res Perspect, 2(5), e00062.
  18. Chen M, Krizaj D, Thoreson WB (2014). Intracellular calcium stores drive slow non-ribbon vesicle release from rod photoreceptors. Front Cell Neurosci, 8, 20.
  19. Ma EY, Lewis A, Barabas P, Stearns G, Suzuki S, Krizaj D, Brockerhoff SE (2013 Sep 12). Loss of Pde6 reduces cell body Ca(2+) transients within photoreceptors. Cell Death Dis, 4, e797.
  20. Luo L, Zhang X, Hirano Y, Tyagi P, Barabas P, Uehara H, Miya TR, Singh N, Archer B, Qazi Y, Jackman K, Das SK, Olsen T, Chennamaneni SR, Stagg BC, Ahmed F, Emerson L, Zygmunt K, Whitaker R, Mamalis C, Huang W, Gao G, Srinivas SP, Krizaj D, Baffi J, Ambati J, Kompella UB, Ambati BK (2013 Apr 23). Targeted intraceptor nanoparticle therapy reduces angiogenesis and fibrosis in primate and murine macular degeneration. ACS Nano, 7(4), 3264-75.
  21. Barabas P, Liu A, Xing W, Chen CK, Tong Z, Watt CB, Jones BW, Bernstein PS, Krizaj D (2013 Mar 26). Role of ELOVL4 and very long-chain polyunsaturated fatty acids in mouse models of Stargardt type 3 retinal degeneration. Proc Natl Acad Sci U S A, 110(13), 5181-6.
  22. Pecar B, Vrtacnik D, Resnik D, Mozek M, Aljancic U, Dolzan T, Amon S, Krizaj D (2013 Mar 04). A strip-type microthrottle pump: modeling, design and fabrication. Sensors (Basel), 13(3), 3092-108.
  23. Molnar T, Barabas P, Birnbaumer L, Punzo C, Kefalov V, Krizaj D (2012 Aug 01). Store-operated channels regulate intracellular calcium in mammalian rods. J Physiol, 590(15), 3465-81.
  24. Xing W, Akopian A, Krizaj D (2012). Trafficking of presynaptic PMCA signaling complexes in mouse photoreceptors requires Cav1.4 alpha1 subunits. Adv Exp Med Biol, 723, 739-44.
  25. Huang W, Xing W, Ryskamp DA, Punzo C, Krizaj D (2011 Nov). Localization and phenotype-specific expression of ryanodine calcium release channels in C57BL6 and DBA/2J mouse strains. Exp Eye Res, 93(5), 700-9.
  26. Barabas P, Huang W, Chen H, Koehler CL, Howell G, John SW, Tian N, Renteria RC, Krizaj D (2011 Aug 29). Missing optomotor head-turning reflex in the DBA/2J mouse. Invest Ophthalmol Vis Sci, 52(9), 6766-73.
  27. Ryskamp DA, Witkovsky P, Barabas P, Huang W, Koehler C, Akimov NP, Lee SH, Chauhan S, Xing W, Renteria RC, Liedtke W, Krizaj D (2011 May 11). The polymodal ion channel transient receptor potential vanilloid 4 modulates calcium flux, spiking rate, and apoptosis of mouse retinal ganglion cells. J Neurosci, 31(19), 7089-101.
  28. Krizaj D, Mercer AJ, Thoreson WB, Barabas P (2011 Jan). Intracellular pH modulates inner segment calcium homeostasis in vertebrate photoreceptors. Am J Physiol Cell Physiol, 300(1), C187-97.
  29. Krizaj D, Huang W, Furukawa T, Punzo C, Xing W (2010 Nov 23). Plasticity of TRPM1 expression and localization in the wild type and degenerating mouse retina. Vision Res, 50(23), 2460-5.
  30. Mizuno F, Barabas P, Krizaj D, Akopian A (2010 Mar 15). Glutamate-induced internalization of Ca(v)1.3 L-type Ca(2+) channels protects retinal neurons against excitotoxicity. J Physiol, 588(Pt 6), 953-66.
  31. Barabas P, Cutler Peck C, Krizaj D (2010). Do Calcium Channel Blockers Rescue Dying Photoreceptors in the Pde6b ( rd1 ) Mouse? Adv Exp Med Biol, 664, 491-9.
  32. Szikra T, Barabas P, Bartoletti TM, Huang W, Akopian A, Thoreson WB, Krizaj D (2009). Calcium homeostasis and cone signaling are regulated by interactions between calcium stores and plasma membrane ion channels. PLoS ONE, 4(8), e6723.
  33. Szikra T, Cusato K, Thoreson WB, Barabas P, Bartoletti TM, Krizaj D (2008 Oct 15). Depletion of calcium stores regulates calcium influx and signal transmission in rod photoreceptors. J Physiol, 586(Pt 20), 4859-75.
  34. Witkovsky P, Gabriel R, Krizaj D (2008 Sep 10). Anatomical and neurochemical characterization of dopaminergic interplexiform processes in mouse and rat retinas. J Comp Neurol, 510(2), 158-74.
  35. Szikra T, Cusato K, Thoreson WH, Bartoletti M and Krizaj D (Sept 4). Store-operated calcium channels regulate visual function. J Physiol.
  36. Zagar T, Krizaj D (2008 Jun). Multivariate analysis of electrical impedance spectra for relaxed and contracted skeletal muscle. Physiol Meas, 29(6), S365-72.
  37. Szikra T, Krizaj D (2007 Sep-Oct). Intracellular organelles and calcium homeostasis in rods and cones. Vis Neurosci, 24(5), 733-43.
  38. Szikra T, Krizaj D (2006 Aug 11). The dynamic range and domain-specific signals of intracellular calcium in photoreceptors. Neuroscience, 141(1), 143-55.
  39. Duncan JL, Yang H, Doan T, Silverstein RS, Murphy GJ, Nune G, Liu X, Copenhagen D, Tempel BL, Rieke F, Krizaj D (2006 Jul 5). Scotopic visual signaling in the mouse retina is modulated by high-affinity plasma membrane calcium extrusion. J Neurosci, 26(27), 7201-11.
  40. Akopian A, Szikra T, Cristofanilli M, Krizaj D (2006). Glutamate-induced Ca2+ influx in third-order neurons of salamander retina is regulated by the actin cytoskeleton. Neuroscience, 138(1), 17-24.
  41. Krizaj D (2005 Dec). Serca isoform expression in the mammalian retina. Exp Eye Res, 81(6), 690-9.
  42. Krizaj D (2005 Dec). Compartmentalization of calcium entry pathways in mouse rods. Eur J Neurosci, 22(12), 3292-6.
  43. Renteria RC, Strehler EE, Copenhagen DR, Krizaj D (2005 May-Jun). Ontogeny of plasma membrane Ca2+ ATPase isoforms in the neural retina of the postnatal rat. Vis Neurosci, 22(3), 263-74.
  44. Krizaj D, Liu X, Copenhagen DR (2004 Aug 2). Expression of calcium transporters in the retina of the tiger salamander (Ambystoma tigrinum). J Comp Neurol, 475(4), 463-80.
  45. Kreft M, Krizaj D, Grilc S, Zorec R (2003 Jul). Properties of exocytotic response in vertebrate photoreceptors. J Neurophysiol, 90(1), 218-25.
  46. Krizaj D, Lai FA, Copenhagen DR (2003 Mar 15). Ryanodine stores and calcium regulation in the inner segments of salamander rods and cones. J Physiol, 547(Pt 3), 761-74.
  47. Krizaj D, Demarco SJ, Johnson J, Strehler EE, Copenhagen DR (2002 Sep 9). Cell-specific expression of plasma membrane calcium ATPase isoforms in retinal neurons. J Comp Neurol, 451(1), 1-21.
  48. Chaudhry FA, Krizaj D, Larsson P, Reimer RJ, Wreden C, Storm-Mathisen J, Copenhagen D, Kavanaugh M, Edwards RH (2001 Dec 17). Coupled and uncoupled proton movement by amino acid transport system N. EMBO J, 20(24), 7041-51.
  49. Kleiman RJ, Tian N, Krizaj D, Hwang TN, Copenhagen DR, Reichardt LF (2000 Jul). BDNF-Induced potentiation of spontaneous twitching in innervated myocytes requires calcium release from intracellular stores. J Neurophysiol, 84(1), 472-83.
  50. Chaudhry FA, Reimer RJ, Krizaj D, Barber D, Storm-Mathisen J, Copenhagen DR, Edwards RH (1999 Dec 23). Molecular analysis of system N suggests novel physiological roles in nitrogen metabolism and synaptic transmission. Cell, 99(7), 769-80.
  51. Krizaj D, Bao JX, Schmitz Y, Witkovsky P, Copenhagen DR (1999 Sep 1). Caffeine-sensitive calcium stores regulate synaptic transmission from retinal rod photoreceptors. J Neurosci, 19(17), 7249-61.
  52. Krizaj D, Gabriel R, Owen WG, Witkovsky P (1998 Sep 7). Dopamine D2 receptor-mediated modulation of rod-cone coupling in the Xenopus retina. J Comp Neurol, 398(4), 529-38.
  53. Krizaj D, Copenhagen DR (1998 Jul). Compartmentalization of calcium extrusion mechanisms in the outer and inner segments of photoreceptors. Neuron, 21(1), 249-56.
  54. Witkovsky P, Schmitz Y, Akopian A, Krizaj D, Tranchina D (1997 Oct 1). Gain of rod to horizontal cell synaptic transfer: relation to glutamate release and a dihydropyridine-sensitive calcium current. J Neurosci, 17(19), 7297-306.
  55. Akopian A, Krizaj D, Witkovsky P (1997 Jul 11). Both high- and low voltage-activated calcium currents contribute to the light-evoked responses of luminosity horizontal cells in the Xenopus retina. Brain Res, 762(1-2), 121-30.
  56. Krizaj D, Copenhagen DR (1997). Ca++-ATP-ase and not Na+/Ca++ exchange controls intracellular calcium in vertebrate photoreceptor inner segments. Invest Ophthalmol Vis Sci, (38), 615.
  57. Krizaj D, Rice ME, Wardle RA, Nicholson C (1996 May 1). Water compartmentalization and extracellular tortuosity after osmotic changes in cerebellum of Trachemys scripta. J Physiol, 492 ( Pt 3), 887-96.
  58. Witkovsky P, Gabriel R, Krizaj D, Akopian A (1995 Apr 11). Feedback from luminosity horizontal cells mediates depolarizing responses of chromaticity horizontal cells in the Xenopus retina. Proc Natl Acad Sci U S A, 92(8), 3556-60.
  59. Krizaj D, Akopian A, Witkovsky P (1994 Sep). The effects of L-glutamate, AMPA, quisqualate, and kainate on retinal horizontal cells depend on adaptational state: implications for rod-cone interactions. J Neurosci, 14(9), 5661-71.
  60. Krizaj D, Witkovsky P (1993 Nov 5). Effects of submicromolar concentrations of dopamine on photoreceptor to horizontal cell communication. Brain Res, 627(1), 122-8.
  61. Krizaj D (1988). Role of electric and ionic factors in the rhizosphere. Speculations in science and technology, (12), 209-211.
  62. Vodovnik L, Stefanovska A, Krizaj D, Turk R, Malezic M (1988). Quantification of wound healing after electrical stimulation. Phys Med Biol, (33), 38.
  63. Krizaj D, Vodovnik L, Pohleven F, Gogala N (1987). 1987. Electrical stimulation: effects on growth and ion accumulation in Lactuca sativa. Journal of Bioelectricity 6, 129-136. Journal of Bioelectricity, (6), 129-136.

Review

  1. Ryskamp DA, Redmon S, Jo AO, Krizaj D (2014 Sep 12). TRPV1 and Endocannabinoids: Emerging Molecular Signals that Modulate Mammalian Vision. [Review]. Cells, 3(3), 914-38.
  2. Krizaj D, Ryskamp DA, Tian N, Tezel G, Mitchell CH, Slepak VZ, Shestopalov VI (2014 Feb). From mechanosensitivity to inflammatory responses: new players in the pathology of glaucoma. [Review]. Curr Eye Res, 39(2), 105-19.
  3. Krizaj D (2012). Calcium stores in vertebrate photoreceptors. [Review]. Adv Exp Med Biol, 740, 873-89.
  4. Krizaj D, Copenhagen DR (2002 Sep 1). Calcium regulation in photoreceptors. [Review]. Front Biosci, 7, d2023-44.
  5. Krizaj D, Hawlina M (2002). Cellular basis for rod-cone interactions in the retina. [Review]. Zdravniski Vestnik, (71), 137-145.
  6. Krizaj D (2000 Sep 1). Mesopic state: cellular mechanisms involved in pre- and post-synaptic mixing of rod and cone signals. [Review]. Microsc Res Tech, 50(5), 347-59.

Book Chapter

  1. Szikra T, Krizaj D (2007). Calcium signals in inner segments of photoreceptors. In Tombran-Tink J, Barnstable C (Eds.), The Visual Transduction Cascade: Basic and Clinical Principles. Totowa: Humana Press.
  2. Krizaj D, Vu T, Copenhagen DR (1999). The shaping, modulation and synaptic transmission of rod and cone light responses. In Toyoda JI (Ed.), The Retinal Basis of Vision (pp. 67-83). Elsevier Press.
  3. Trontelj Z, Pirnat J, Luznik J, Jazbinsek V, Valencic V, Krizaj D, Vodovnik L, Jercinovic A (1989). Measurement of magnetic field near acute surgical injury on the rabbit's thigh. In Samuelson SJ, Stroink G, Korani M (Eds.), Advances in Biomagnetism (pp. 517-520). New York: Plenum Press.

Conference Proceedings

  1. Krizaj D, Huang H, Cutler-Peck C and Zou J (). Calcium signaling in rod and cone photoreceptor degeneration. ISER.
  2. Krizaj D, CW Morgans, WH Thoreson, J Zou, H Yang, L Birnbaumer, J Duncan and Szikra T (). TRPC6 modulates cone signals in the vertebrate retina. FASEB.
  3. Krizaj D, Thoreson WB, Rohrer B, Duncan J and Szikra T (). TRPC channels modulate calcium homeostasis, apoptosis and synaptic transmission at the photoreceptor synapse. CaBP.
  4. Krizaj D (05/2007). The Neuroscience of Feelings. 3rd International Psychotherapeutic Conference, Rogla, Slovenia: Kairos , 1, 15.
  5. Szikra T, Cusato K, Krizaj D (2006). Store-operated channels regulate Ca in photoreceptors. Proc IBRO, Budapest, Hungary.
  6. Krizaj D (2006). Regulation of photoreceptor signaling by plasma membrane calcium transporters. Proc. FASEB, Indian Wells.
  7. Szikra T, Cusato K, Krizaj D (2006). Store-operated channels regulate Ca in photoreceptors. FASEB, Indian Wells, CO, 59(5).
  8. Krizaj D (2006). Regulation of photoreceptor signaling by plasma membrane and calcium store transporters. Proc 17th ISER, Buenos Aires, Argentina.
  9. Akopian A, Szikra T, Krizaj D (2004). The actin cytoskeleton regulates voltage- and glutamate-activated Ca2+ influx in retinal neurons". Proc. 14th Neuropharmacology Conf, San Diego.
  10. Krizaj D, Tempel BL and Duncan J (2004). Localization and functional contribution of calcium extrusion mechanisms to light-evoked signaling in the retina. Proc. FASEB on Calcium Signaling, Aspen.
  11. Krizaj D, Renteria JC, Takahashi KI, Copenhagen DR (2002). Glutamine transporters regulate retinal function. Proc. FASEB.
  12. Krizaj D, Chaudhry FA, Takahashi KI, Edwards R, Copenhagen DR (2000). Endogenous prevention of glutamate excitotoxicity: glutamate: glutamine cycling in the retina. Proc. 3rd Slovenian Congress in Ophthalmology , (3), 27.
  13. Krizaj D, Veranic P, Copenhagen DR (2000). Control of the intracellular calcium concentration in vertebrate photoreceptors. Proc. 3rd Slovenian Congress in Ophthalmology, (3), 94.
  14. Kreft M, Krizaj D, Rupnik M, Copenhagen DR, Zorec R (2000). Bell-shaped calcium-dependency of exocytotic response in vertebrate photoreceptors. Proc. 3rd Slovenian Congress in Ophthalmology, (3), 95.
  15. Witkovsky P, Akopian A, Krizaj D, Zhang J (1994). A cellular basis for light and dark adaptation in the Xenopus retina. Great Basin Visual Science Symposium, 49-57.
  16. Krizaj D, Akopian A, Witkovsky P (1994). Dopamine and synaptic integration at the Xenopus photoreceptor output synapse. Proc. FASEB, 15.
  17. Krizaj D, Rice M, Nicholson C (1992). The relationship between the geometry and extracellular volume fraction in an isolated brain tissue. Proc. Slov. Symp. Biophys, (1), 6.
  18. Trontelj Z, Pirnat J, Luznik J, Jazbinsek V, Valencic V, Krizaj D, Vodovnik L (1989). Magnetic fields near acute wound on the rabbit's thigh. Joint Meeting Aust.FRG Swiss, YU Biophysical. Soc., Toodtmoos.
  19. Krizaj D, Pohleven F, Zel J, Lestan D, Gogala N, Vodovnik L (1988). Electrical and electromagnetic stimulation as a method to study growth and morphogenesis in plants and fungi. Proc.6th Congress Fed.Eur.Soc.Plant Physiol.
  20. Vodovnik L, Stefanovska A, Krizaj D, Benko H, Turk R, Malezic M (1988). Electronic healing of chronic wounds. Proc. 5th Conf.Biomed.Phys. and Eng, 82-84.

Abstract

  1. Krizaj D, Ducan JL, Yang H, Doan T, Silverstein R, Murphy GJ, Tempel BL (2006). Expression and function of high-affinity calcium transport at the photoreceptor synapse [Abstract]. IOVS.
  2. Szikra T, Cusato K, Krizaj D (2006). Store-operated channels regulate baseline Ca in light-adapted photoreceptors [Abstract]. IOVS.
  3. Szikra T, Krizaj D (2005). The role of voltage-operated Ca channels, endoplasmic reticulum and mitochondria in compartmentalization of Ca homeostasis in the photoreceptor inner segment [Abstract]. IOVS.
  4. Krizaj D (2005). Expression of transient receptor potential channels (TRPCs) in the mouse retina [Abstract]. IOVS.
  5. Akopian A, Szikra T, Krizaj D (2005). The actin cytoskeleton regulates Ca sources in salamander retinal neurons [Abstract]. IOVS.
  6. Akopian A, Szikra T, Krizaj D (2004). The actin cytoskeleton regulates voltage- and receptor-activated Ca2+ accumulation in salamander retinal ganglion cells [Abstract]. Soc. Neurosci.
  7. Szikra T, Krizaj D (2004). Calcium stores and store-operated calcium channels in photoreceptors [Abstract]. FASEB on Retinal Circuits.
  8. Szikra T, Krizaj D (2004). Calcium stores and store-operated calcium channels in photoreceptors [Abstract]. IOVS.
  9. Krizaj D, Yang H, Nune G, Liu XL, Tempel BL, Copenhagen, D, Duncan JL (2004). The timing and amplitude of scotopic visual signals are regulated by calcium extrusion [Abstract]. IOVS .
  10. Copenhagen DR, Renteria RC, Gillespie PG, Strehler EE, Krizaj D (2003). Plasma membrane calcium ATPases 1b and 4b drive calcium extrusion from photoreceptor synaptic terminals [Abstract]. IOVS .
  11. Krizaj D, Copenhagen DR (2003). Ryanodine receptors, PMCAs and mitochondria interact in inner segments of salamander rods and cones [Abstract]. IOVS.
  12. Copenhagen DR, Renteria RC, Takahashi KI, Krizaj D (2002). Glutamate: glutamine cycling supports synaptic transmission in the retina [Abstract]. IOVS .
  13. Krizaj D, DeMarco S, Johnson J, Strehler EE, Copenhagen DR (2001). Differential expression of plasma membrane calcium ATPases in graded and spiking retinal neurons [Abstract]. Soc. Neurosci, (397), 19a.
  14. Copenhagen DR, Krizaj D, Chaudhry FA, Edwards R, Takahashi KI (2000). Glutamate: glutamine cycling in the retina is facilitated by a system N-type glutamine transporter localized to Muller cells [Abstract]. Soc. Neurosci, 26.
  15. Krizaj D, Copenhagen DR (2000). pH regulates calcium ATPase-mediated calcium extrusion from photoreceptors [Abstract]. Soc. Neurosci, (26).
  16. Krizaj D, Takahashi KI, Copenhagen DR (1999). K+/H+ exchanger regulates pH in photoreceptors [Abstract]. Soc.Neurosci, (25), 138.
  17. Bao JX, Krizaj D, Copenhagen DR (1998). Calcium-mediated inactivation of calcium current in rod photoreceptors [Abstract]. Soc.Neurosci, (24), 643.
  18. Krizaj D, Copenhagen DR, Witkovsky P (1998). Neuromodulation controls the adaptational switch at the photoreceptor synapse [Abstract]. Retinal Adaptation Workshop.
  19. Krizaj D, Schmitz Y, Bao JX, Witkovsky P, Copenhagen DR (1998). The action of caffeine on transmitter release from vertebrate rods [Abstract]. Soc.Neurosci, (24), 1027.
  20. Krizaj D, Bao JX, Copenhagen, DR (1997). Intracellular calcium stores in vertebrate rods and cones [Abstract]. Soc. Neurosci, (23), 2360.
  21. Krizaj D, Copenhagen DR (1996). Differential calcium regulation in rod and cone inner segments [Abstract]. Soc.Neurosci, (22), 1816.
  22. Witkovsky P, Gabriel R, Krizaj D (1996). Modulation of rod-cone coupling in the Xenopus retina [Abstract]. IOVS , (37), 675.
  23. Akopian A, Krizaj D, Witkovsky P (1995). Contribution of T- and L- type Ca currents to the light-induced responses of retinal horizontal cells [Abstract]. Soc.Neurosci, (21), 206.
  24. Krizaj D, Gabriel R, Zhang J, Witkovsky P (1994). The vertical pathway in the retina is modulated by D2 dopamine receptor [Abstract]. Soc.Neurosci, (20), 967.
  25. Witkovsky P, Gabriel R, Krizaj D, Akopian A (1994). Feedback to cones by luminosity horizontal cells controls the depolarizing response of chromatic horizontal cells [Abstract]. Soc.Neurosci, (20), 217.
  26. Krizaj D, Akopian A, Witkovsky P (1993). Separate quisqualate (rod input) and kainate (cone input) receptors mediate rod-cone interaction in L-horizontal cells of the Xenopus retina [Abstract]. Soc.Neurosci, (19), 230.
  27. Krizaj D, Witkovsky P (1992). Threshold effects of dopamine in the Xenopus retina [Abstract]. Soc.Neurosci, (18), 840.
  28. Krizaj D, Rice ME, Nicholson C ( 1991). Volume regulation in isolated turtle cerebellum under hyper- and hypoosmotic conditions [Abstract]. Soc. Neurosci, (17), 240.

Other

  1. Krizaj D, Szikra T (2005). Compartmentalization of Calcium Signaling Mechanisms in Vertebrate Photoreceptors. Bay Area Vision Research Day, Berkeley, CA.
  2. Krizaj D (1994). Ph.D. Thesis, Synaptic integration and neuromodulation at the photoreceptor output synapse: mechanisms and functional significance. New York University.