Harshwardhan M. Thaker, MD, PhD

Languages

  • English

Academic Information

  • Departments: Pathology - Adjunct Associate Professor
  • Divisions: Anatomic Pathology

Board Certification

  • American Board of Pathology (Anatomic)

Academic Office Information

  • 801-662-2159
  • Primary Children's Hospital
    Department of Pathology
    100 N Mario Capecchi Drive
    Salt Lake City, UT 84113

Email: harsh.thaker@utah.edu

Education History

Type School Degree
Residency Columbia Univ- NY Presbyterian Hosp
Anatomic Pathology
Resident
Research Fellow Stanford Univ-Howard Hughes Med Inst.
Wnt genes
Research Fellow
Doctoral Training Yale University
Genetics and Development in Drosophila
Ph.D.
Internship B.Y.L. Nair Charitable Hospital
General Medicine
Intern
Professional Medical University of Bombay, Topiwala National Medical College
M.B.B.S.

Global Impact

Education History

Type School Degree Country
Internship B.Y.L. Nair Charitable Hospital
General Medicine
Intern India
Professional Medical University of Bombay, Topiwala National Medical College
M.B.B.S. India

Selected Publications

Journal Article

  1. Furtado LV, Thaker HM, Erickson LK, Shirts BH, Opitz JM (2011 Nov-Dec). Cervical ribs are more prevalent in stillborn fetuses than in live-born infants and are strongly associated with fetal aneuploidy. Pediatr Dev Pathol, 14(6), 431-7.
  2. Wallander M, Layfield LJ, Jarboe E, Emerson L, Liu T, Thaker H, Holden J, Tripp S (2010 May). Follicular variant of papillary carcinoma: reproducibility of histologic diagnosis and utility of HBME-1 immunohistochemistry and BRAF mutational analysis as diagnostic adjuncts. Appl Immunohistochem Mol Morphol, 18(3), 231-5.
  3. Schlaberg R, Choe DJ, Brown KR, Thaker HM, Singh IR (2009 Sep 22). XMRV is present in malignant prostatic epithelium and is associated with prostate cancer, especially high-grade tumors. Proc Natl Acad Sci U S A, 106(38), 16351-6.
  4. Adibi JJ, Hauser R, Williams PL, Whyatt RM, Thaker HM, Nelson H, Herrick R, Bhat HK (2009). Placental biomarkers of phthalate effects on mRNA transcription: application in epidemiologic research. Environmental Health, 8, 20.
  5. Suciu-Foca N, Feirt N, Zhang QY, Vlad G, Liu Z, Lin H, Chang CC, Ho EK, Colovai AI, Kaufman H, DAgati VD, Thaker HM, Remotti H, Galluzzo S, Cinti P, Rabitti C, Allendorf J, Chabot J, Caricato M, Coppola R, Berloco P, Cortesini R (2007 Jun 1). Soluble Ig-like transcript 3 inhibits tumor allograft rejection in humanized SCID mice and T cell responses in cancer patients. J Immunol, 178(11), 7432-41.
  6. Lee YM, Cleary-Goldman J, Thaker HM, Simpson LL (2006 Sep). Antenatal sonographic prediction of twin chorionicity. Am J Obstet Gynecol, 195(3), 863-7.
  7. McMinn J, Wei M, Schupf N, Cusmai J, Johnson EB, Smith AC, Weksberg R, Thaker HM, Tycko B (2006 Jun-Jul). Unbalanced placental expression of imprinted genes in human intrauterine growth restriction. Placenta, 27(6-7), 540-9.
  8. Qiu W, Schonleben F, Thaker HM, Goggins M, Su GH (2006 May 11). A novel mutation of STK11/LKB1 gene leads to the loss of cell growth inhibition in head and neck squamous cell carcinoma. Oncogene, 25(20), 2937-42.
  9. McMinn J, Wei M, Sadovsky Y, Thaker HM, Tycko B (2006 Feb-Mar). Imprinting of PEG1/MEST isoform 2 in human placenta. Placenta, 27(2-3), 119-26.
  10. Li CM, Guo M, Salas M, Schupf N, Silverman W, Zigman WB, Husain S, Warburton D, Thaker H, Tycko B (2006). Cell type-specific over-expression of chromosome 21 genes in fibroblasts and fetal hearts with trisomy 21. BMC Med Genet, 7(1), 24.
  11. Yuan E, Li CM, Yamashiro DJ, Kandel J, Thaker H, Murty VV, Tycko B (2005 Sep). Genomic profiling maps loss of heterozygosity and defines the timing and stage dependence of epigenetic and genetic events in Wilms' tumors. Mol Cancer Res, 3(9), 493-502.
  12. Thaker HM, Berlin A, Tycko B, Goldstein DP, Berkowitz RS, Castrillon DH, Genest DR (2004 Aug). Immunohistochemistry for the imprinted gene product IPL/PHLDA2 for facilitating the differential diagnosis of complete hydatidiform mole. J Reprod Med, 49(8), 630-6.
  13. Abraham SS, Osorio JC, Homma S, Wang J, Thaker HM, Liao JK, Mital S (2004 Mar). Simvastatin preserves cardiac function in genetically determined cardiomyopathy. J Cardiovasc Pharmacol, 43(3), 454-61.
  14. Hughes SA, Thaker HM, Racaniello VR (2003 Dec 23). Transgenic mouse model for echovirus myocarditis and paralysis. Proc Natl Acad Sci U S A, 100(26), 15906-11.
  15. Saxena A, Frank D, Panichkul P, Van den Veyver IB, Tycko B, Thaker H (2003 Sep-Oct). The product of the imprinted gene IPL marks human villous cytotrophoblast and is lost in complete hydatidiform mole. Placenta, 24(8-9), 835-42.
  16. Hopkins KM, Wang X, Berlin A, Hang H, Thaker HM, Lieberman HB (2003 Sep 1). Expression of mammalian paralogues of HRAD9 and Mrad9 checkpoint control genes in normal and cancerous testicular tissue. Cancer Res, 63(17), 5291-8.
  17. Li CM, Guo M, Borczuk A, Powell CA, Wei M, Thaker HM, Friedman R, Klein U, Tycko B (2002 Jun). Gene expression in Wilms' tumor mimics the earliest committed stage in the metanephric mesenchymal-epithelial transition. Am J Pathol, 160(6), 2181-90.
  18. Thaker HM, Kankel DR (1992 Aug). Mosaic analysis gives an estimate of the extent of genomic involvement in the development of the visual system in Drosophila melanogaster. Genetics, 131(4), 883-94.

Review

  1. Thaker, HM (2005). The partly molar pregnancy that is not a partial mole. [Review]. Pediatr Dev Pathol, 8(2), 146-147.
  2. Horn C, Thaker HM, Tampakopoulou DA, De Serres LM, Keller JL, Haddad J Jr (2001 Feb). Tongue lesions in the pediatric population. [Review]. Otolaryngol Head Neck Surg, 124(2), 164-9.

Book Chapter

  1. Thaker HM, Shutter JS (2006). Pediatric and Placental Pathology. In Lefkowitch J (Ed.), Anatomic Pathology board review (pp. 551-570). Saunders.

Conference Proceedings

  1. Hall BJ, Kennedy AM, Thaker HM (). Hydrometrocolpos Associated With Fetal Vascular Thrombosis in the Placenta. Poster#96. Abstracts and Case Studies From the College of American Pathologists 2010 Annual Meeting (CAP '10). Archives of Pathology & Laboratory Medicine. 134(9), 1309.
  2. Harrison KB, Ilzarbe M, Thaker H, Warburton D (2002). Apparently monochorionic placenta in XX/XY dizygotic twins. A106. Genet Med, 4, 203.

Case Report

  1. Chan M, Scaife C, Thaker HM, Adler DG (2009). Adenocarcinoma of the pancreas undetected by multidetector CT, endoscopic ultrasound, or intraoperative ultrasound. JOP, 10(5), 554-6.
  2. Baxi L, Brown S, Desai K, Thaker H (2009). Recurrent cystic hygroma with hydrops. Fetal Diagn Ther, 25(1), 127-9.
  3. Baxi L, Brown S, Thaker HM (2007). False-positive quadruple screen test for trisomy 18 in a patient with a fetus with Bloom's syndrome. Fetal Diagn Ther, 22(4), 318-20.
  4. Akman HO, Karadimas C, Gyftodimou Y, Grigoriadou M, Kokotas H, Konstantinidou A, Anninos H, Patsouris E, Thaker HM, Kaplan JB, Besharat I, Hatzikonstantinou K, Fotopoulos S, Dimauro S, Petersen MB (2006 Oct). Prenatal diagnosis of glycogen storage disease type IV. Prenat Diagn, 26(10), 951-5.
  5. Ramaswamy P, Haberman S, Kleinman C, Lytrivi ID, Thaker HM (2006 Sep-Oct). Ascending aortic aneurysm in a fetus due to a benign nodular myofibroblastic lesion. Cardiovasc Pathol, 15(5), 294-6.
  6. Monaco SE, Davis M, Huang A, Bhagat G, Baergen RN, Lorenz JM, Chung WK, Thaker HM (2005). Alpha-Thalassemia Major presenting in a term neonate without hydrops. Pediatr Dev Pathol, 8(6), 706-709.
  7. Monaco SE, Gersony WM, Thaker HM (2004 Oct). Divided left atrium with obstruction of pulmonary venous return in the setting of hypoplasia of the left heart. Cardiol Young, 14(5), 553-6.
  8. Fisher RA, Nucci MR, Thaker HM, Weremowicz S, Genest DR, Castrillon DH (2004 Sep). Complete hydatidiform mole retaining a chromosome 11 of maternal origin: molecular genetic analysis of a case. Mod Pathol, 17(9), 1155-60.
  9. Shevell T, Malone FD, Weintraub J, Thaker HM, Dalton ME (2004 Feb). Radiofrequency ablation in a monochorionic twin discordant for fetal anomalies. Am J Obstet Gynecol, 190(2), 575-6.
  10. Selamet SE, Hsu DT, Thaker HM, Gersony WM (2004 Jan-Feb). Complete atresia of coronary ostia in pulmonary atresia and intact ventricular septum. Pediatr Cardiol, 25(1), 67-9.
  11. Renwick N, Nasr SH, Chung WK, Garvin J, Markowitz GS, Marboe C, Thaker HM, DAgati VD (2003 Apr). Foamy podocytes. Am J Kidney Dis, 41(4), 891-6.

Editorial

  1. Thaker HM and Vernon DD (). The autopsy: Underutilized weapon in the pediatric intensive care unit. Pediatric Critical Care Medicine, 12(5), pp.