Gregory S. Hageman, PhD
- The Biology, Genetics and Development of Diagnostic and Therapeutic Modalities for the Treatment of Age-Related Macular Degeneration and its Co-Segregating Diseases
- Departments: Ophthalmology/Visual Sciences - Professor
Academic Office Information
John A. Moran Eye Center
65 N Mario Capecchi
Salt Lake City, UT 84132
Gregory Hageman is the John A. Moran Presidential Endowed Chair and the Executive Director of the Moran Eye Center for Translational Medicine at the University of Utah Moran Eye Center. He is an active member of professional and honorary organizations, and has served on numerous national and international advisory boards, service panels, and review committees. He has also been an advisor to numerous pharmaceutical and diagnostic companies.
Dr. Hageman’s primary research interest for over 20 years has been directed toward assessment of pathways involved in the etiology of age-related macular degeneration (AMD). Dr. Hageman and his colleagues discovered that AMD is characterized by robust activation of the complement cascade in the ocular macula and that variations in complement genes, including Complement Factor H (CFH), account for greater than 50% of risk for AMD in Caucasians. More recent discoveries relate to the role of the choriocapillaris in severe forms of AMD and diseases that co-segregate with it. Dr. Hageman has twice briefed the US Congress on his research findings and has received numerous awards for his contributions to AMD research. A major goal of Dr. Hageman’s current efforts is to expedite the pace at which basic scientific discoveries are translated into clinically effective therapies for the treatment of AMD and its co-segregating diseases.
Greg and his wife, Jill, have been married 33 years. They have two wonderful children, Nicholas and Courtney.
|Doctoral Training||University of Southern California
|Undergraduate||University of Southern California
- Gorusupudi A, Liu A, Hageman GS, Bernstein PS (2016). Associations of human retinal very long-chain polyunsaturated fatty acids with dietary lipid biomarkers. J Lipid Res, 57(3), 499-508.
- Keenan TD, Toso M, Pappas C, Nichols L, Bishop PN, Hageman GS (2015). Assessment of Proteins Associated With Complement Activation and Inflammation in Maculae of Human Donors Homozygous Risk at Chromosome 1 CFH-to-F13B. Invest Ophthalmol Vis Sci, 56(8), 4870-9.
- Wu Z, Luu CD, Ayton LN, Goh JK, Lucci LM, Hubbard WC, Hageman JL, Hageman GS, Guymer RH (2015). Fundus autofluorescence characteristics of nascent geographic atrophy in age-related macular degeneration. Invest Ophthalmol Vis Sci, 56(3), 1546-52.
- Wu Z, Luu CD, Ayton LN, Goh JK, Lucci LM, Hubbard WC, Hageman JL, Hageman GS, Guymer RH (2014). Optical coherence tomography-defined changes preceding the development of drusen-associated atrophy in age-related macular degeneration. Ophthalmology, 121(12), 2415-22.
- Finger RP, Wu Z, Luu CD, Kearney F, Ayton LN, Lucci LM, Hubbard WC, Hageman JL, Hageman GS, Guymer RH (2014). Reticular pseudodrusen: a risk factor for geographic atrophy in fellow eyes of individuals with unilateral choroidal neovascularization. Ophthalmology, 121(6), 1252-6.
- Moran Eye Center Researchers Selected to International Effort by Chan Zuckerberg Initiative to Map All Human Cells
- Moran Eye Center Celebrates Achievements of Donors and Faculty Holding Endowed Chairs and Professorships
- Study Finds Women Who Have Hypertensive Disorders during Pregnancy at Greater Risk for Blinding Disease
- Moran Team Turning Genetic Discoveries Into Treatments For Age-Related Macular Degeneration
- Faculty and Staff Awards and Recognitions for September 2015
- Moran Eye Center's Voyant Biotherapeutics, LLC, Enters Into Exclusive R&D Collaboration Agreement with Allergan, Inc.