Gregory S. Hageman, PhD

Research Interests

  • The Biology, Genetics and Development of Diagnostic and Therapeutic Modalities for the Treatment of Age-Related Macular Degeneration and its Co-Segregating Diseases


  • English

Academic Information

  • Departments: Ophthalmology/Visual Sciences - Professor

Academic Office Information

  • John A. Moran Eye Center
    65 N Mario Capecchi
    Salt Lake City, UT 84132

Academic Bio

Gregory Hageman is the John A. Moran Presidential Endowed Chair and the Executive Director of the Moran Eye Center for Translational Medicine at the University of Utah Moran Eye Center. He is an active member of professional and honorary organizations, and has served on numerous national and international advisory boards, service panels, and review committees. He has also been an advisor to numerous pharmaceutical and diagnostic companies.

Dr. Hageman’s primary research interest for over 20 years has been directed toward assessment of pathways involved in the etiology of age-related macular degeneration (AMD). Dr. Hageman and his colleagues discovered that AMD is characterized by robust activation of the complement cascade in the ocular macula and that variations in complement genes, including Complement Factor H (CFH), account for greater than 50% of risk for AMD in Caucasians. More recent discoveries relate to the role of the choriocapillaris in severe forms of AMD and diseases that co-segregate with it. Dr. Hageman has twice briefed the US Congress on his research findings and has received numerous awards for his contributions to AMD research. A major goal of Dr. Hageman’s current efforts is to expedite the pace at which basic scientific discoveries are translated into clinically effective therapies for the treatment of AMD and its co-segregating diseases.
Greg and his wife, Jill, have been married 33 years. They have two wonderful children, Nicholas and Courtney.

Education History

Type School Degree
Doctoral Training University of Southern California
Undergraduate University of Southern California
Biological Sciences