Dan Kaufmann, PhD

Languages

  • English
  • Hebrew

Academic Information

  • Departments: Neurology - Research Assistant Professor
  • Divisions: Headache and Neuro-Ophthalmology

Education History

Type School Degree
Research Fellow University of Utah
Neurophysiology
Postdoctoral Research Fellow
Research Fellow University of Utah
Pharmacology and Toxicology
Postdoctoral Research Fellow
Doctoral Training Hebrew University of Jerusalem, School of Pharmacy
Pharmaceutics and Medicinal Chemistry
Ph.D.
Undergraduate Hebrew University of Jerusalem
Chemistry and Biology
B.Sc.
Fellowship University of Utah
Neurophysiology
Postdoctoral Research Associate

Global Impact

Education History

Type School Degree Country
Doctoral Training Hebrew University of Jerusalem, School of Pharmacy
Pharmaceutics and Medicinal Chemistry
Ph.D. Israel
Undergraduate Hebrew University of Jerusalem
Chemistry and Biology
B.Sc. Israel

Selected Publications

Journal Article

  1. Metcalf CS, Klein BD, McDougle DR, Zhang L, Kaufmann D, Bulaj G, White HS (2017 Jan 18). Preclinical evaluation of intravenous NAX 810-2, a novel GalR2-preferring analog, for anticonvulsant efficacy and pharmacokinetics.LID - 10.1111/epi.13647 [doi]. (Epub ahead of print) Epilepsia.
  2. Kaufmann D, West PJ, Smith MD, Yagen B, Bialer M, Devor M, White HS, Brennan KC (2016 Nov 24). sec-Butylpropylacetamide (SPD), a new amide derivative of valproic acid for the treatment of neuropathic and inflammatory pain. Pharmacol Res, 117, 129-139.
  3. Kaufmann D, Theriot JJ, Zyuzin J, Service CA, Chang JC, Tang YT, Bogdanov VB, Multon S, Schoenen J, Ju YS, Brennan KC (2016 Aug 25). Heterogeneous incidence and propagation of spreading depolarizations.LID - 0271678X16659496 [pii]. (Epub ahead of print) J Cereb Blood Flow Metab.
  4. Kaufmann D, Bates EA, Yagen B, Bialer M, Saunders GH, Wilcox K, White HS, Brennan KC (). sec-Butylpropylacetamide (SPD) has antimigraine properties. Cephalalgia, 36(10), 924-35.
  5. Pouliot W, Bialer M, Hen N, Shekh-Ahmad T, Kaufmann D, Yagen B, Ricks K, Roach B, Nelson C, Dudek FE (2013 Feb 12). A comparative electrographic analysis of the effect of sec-butyl-propylacetamide on pharmacoresistant status epilepticus. Neuroscience, 231, 145-56.
  6. White HS, Alex AB, Pollock A, Hen N, Shekh-Ahmad T, Wilcox KS, McDonough JH, Stables JP, Kaufmann D, Yagen B, Bialer M (2012 Jan). A new derivative of valproic acid amide possesses a broad-spectrum antiseizure profile and unique activity against status epilepticus and organophosphate neuronal damage. Epilepsia, 53(1), 134-46.
  7. Pessah N, Kaufmann D, Yagen B, Hen N, Wlodarczyk B, Finnell RH, Bialer M (2010 Oct). Comparative pharmacodynamic and pharmacokinetic analysis of two anticonvulsant halo derivatives of 2,2,3,3-tetramethylcyclopropanecarboxamide, an amide of a cyclic analog of valproic acid. Epilepsia, 51(10), 1944-53.
  8. Kaufmann D, Yagen B, Minert A, Wlodarczyk B, Finnell RH, Schurig V, Devor M, Bialer M (2010 Jun). Evaluation of the antiallodynic, teratogenic and pharmacokinetic profile of stereoisomers of valnoctamide, an amide derivative of a chiral isomer of valproic acid. Neuropharmacology, 58(8), 1228-36.
  9. Kaufmann D, Bialer M, Shimshoni JA, Devor M, Yagen B (2009 Nov 26). Synthesis and evaluation of antiallodynic and anticonvulsant activity of novel amide and urea derivatives of valproic acid analogues. J Med Chem, 52(22), 7236-48.
  10. Okada A, Onishi Y, Yagen B, Shimshoni JA, Kaufmann D, Bialer M, Fujiwara M (2008 Sep). Tetramethylcyclopropyl analogue of the leading antiepileptic drug, valproic acid: evaluation of the teratogenic effects of its amide derivatives in NMRI mice. Birth Defects Res A Clin Mol Teratol, 82(9), 610-21.
  11. Kaufmann D, Yagen B, Minert A, Tal M, Devor M, Bialer M (2008 Mar). Evaluation of the enantioselective antiallodynic and pharmacokinetic profile of propylisopropylacetamide, a chiral isomer of valproic acid amide. Neuropharmacology, 54(4), 699-707.