Todd M. Darlington, PhD

Research Interests

  • Psychiatric Genetics
  • Statistical Genetics
  • Models, Statistical
  • Autism Spectrum Disorders
  • Suicide

Languages

  • English

Academic Information

  • Departments: Psychiatry - Adjunct Instructor
  • Divisions: Adult Psychiatry

Academic Office Information

  • 801-213-5763
  • Huntsman Cancer Institute
    2000 Circle of Hope, Room: 4121
    Salt Lake City, UT 84112

Research Statement

I am primarily interested in parsing genetic data to identify the etiology of complex disease. I develop statistical methods for genetic data mining, and my research focuses on complex psychiatric disorders including autism spectrum disorder and suicidal behaviors.

Education History

Type School Degree
Fellowship University of Utah
Psychiatry
Postdoctoral Research Associate
Certification University of Colorado Boulder
Behavioral Genetics
Certificate
Doctoral Training University of Colorado Boulder
Dual Degree: Integrative Physiology, Neuroscience
Ph.D.
Undergraduate DePauw University
Biology
B.A.

Selected Publications

Journal Article

  1. Waller RG, Darlington TM, Wei X, Madsen MJ, Thomas A, Curtin K, Coon H, Rajamanickam V, Musinsky J, Jayabalan D, Atanackovic D, Rajkumar SV, Kumar S, Slager S, Middha M, Galia P, Demangel D, Salama M, Joseph V, McKay J, Offit K, Klein RJ, Lipkin SM, Dumontet C, Vachon CM, Camp NJ (02/01/2018). Novel pedigree analysis implicates DNA repair and chromatin remodeling in multiple myeloma risk. PLoS Genet, 14(2), e1007111.
  2. Woodbury-Smith M, Bilder DA, Morgan J, Jerominski L, Darlington TM, Dyer T, Paterson A, Coon H (02/2017). Combined genome-wide linkage and targeted association analysis of head circumference in autism spectrum disorder families. J Neurodev Disord, 9(1).
  3. Darlington TM, McCarthy RD, Cox RJ, Miyamoto-Ditmon J, Gallego X, Ehringer MA (06/2016). Voluntary wheel running reduces voluntary consumption of ethanol in mice: identification of candidate genes through striatal gene expression profiling. Genes, Brain and Behavior, 15(5), 474-490.
  4. Kamens HM, Corley RP, Richmond PA, Darlington TM, Dowell R, Hopfer CJ, Stallings MC, Hewitt JK, Brown SA, Ehringer MA (04/16/2016). Evidence for Association Between Low Frequency Variants in CHRNA6/CHRNB3 and Antisocial Drug Dependence. Behav Genet, 46(5), 693-704.
  5. Darlington TM, Pimentel R, Smith K, Bakian AV, Jerominski L, Cardon J, Camp NJ, Callor WB, Grey T, Singleton M, Yandell M, Renshaw PF, Yurgelun-Todd DA, Gray D, Coon H (2014). Identifying rare variants for genetic risk through a combined pedigree and phenotype approach: application to suicide and asthma. Transl Psychiatry, 4, e471.
  6. Coon H, Darlington TM, Pimentel R, Smith KR, Huff C, Hu H, Jerominski L, Hansen J, Klein M, Callor WB, Byrd J, Bakian A, Crowell SE, McMahon WM, Rajamanickam V, Camp NJ, McGlade E, Renshaw P, Yurgelun-Todd D, Grey T, Gray D (2013). Genetic risk factors in two Utah pedigrees at high risk for suicide. Transl Psychiatry, 3, e325.