Olga J. Baker, DDS, PhD

Research Interests

  • Salivary Glands
  • Tissue Engineering
  • Sjogren's Syndrome

Languages

  • English
  • Spanish

Academic Information

  • Departments: Dentistry - Associate Professor

Academic Office Information

  • 801-587-1773
  • College of Health
    School of Dentistry
    383 Colorow Building, Room: 289A
    Salt Lake City, UT 84108

Education History

Type School Degree
Doctoral Training Central University of Venezuela
Biochemistry
Ph.D.
Professional Dental Central University of Venezuela
Dental Surgery
D.D.S.

Global Impact

Education History

Type School Degree Country
Doctoral Training Central University of Venezuela
Biochemistry
Ph.D. Venezuela
Professional Dental Central University of Venezuela
Dental Surgery
D.D.S. Venezuela

Selected Publications

Journal Article

  1. Dean S, Wang CS, Nam K, Maruyama CL, Trump BG, Baker OJ (2018). Aspirin Triggered Resolvin D1 reduces inflammation and restores saliva secretion in a Sjögren's syndrome mouse model. Rheumatology (Oxford), 58(7), 1285-1292.
  2. Nam K, Dean SM, Brown CT, Smith RJ Jr, Lei P, Andreadis ST, Baker OJ (2019). Synergistic effects of laminin-1 peptides, VEGF and FGF9 on salivary gland regeneration. Acta Biomater, 91, 186-194.
  3. Maruyama CL, Monroe MM, Hunt JP, Buchmann L, Baker OJ (2018). Comparing human and mouse salivary glands: A practice guide for salivary researchers. Oral Dis, 25(2), 403-415.
  4. Wang CS, Baker OJ (2018). The G-Protein-Coupled Receptor ALX/Fpr2 Regulates Adaptive Immune Responses in Mouse Submandibular Glands. Am J Pathol, 188(7), 1555-1562.
  5. Nam K, Maruyama CL, Wang CS, Trump BG, Lei P, Andreadis ST, Baker OJ (2017). Laminin-111-derived peptide conjugated fibrin hydrogel restores salivary gland function. PLoS ONE, 12(11), e0187069.
  6. Nam K, Wang CS, Maruyama CLM, Lei P, Andreadis ST, Baker OJ (2017). L1 Peptide-Conjugated Fibrin Hydrogels Promote Salivary Gland Regeneration. J Dent Res, 96(7), 798-806.
  7. Wang CS, Maruyama CL, Easley JT, Trump BG, Baker OJ (2017). AT-RvD1 Promotes Resolution of Inflammation in NOD/ShiLtJ mice. Sci Rep, 7, 45525.
  8. Leigh NJ, Nelson JW, Mellas RE, McCall AD, Baker OJ (2014). Three-dimensional cultures of mouse submandibular and parotid glands: a comparative study. J Tissue Eng Regen Med, 11(3), 618-626.
  9. Easley JT, Maruyama CL, Wang CS, Baker OJ (2016). AT-RvD1 combined with DEX is highly effective in treating TNF-α-mediated disruption of the salivary gland epithelium. Physiol Rep, 4(19).
  10. Nam K, Jones JP, Lei P, Andreadis ST, Baker OJ (2016). Laminin-111 Peptides Conjugated to Fibrin Hydrogels Promote Formation of Lumen Containing Parotid Gland Cell Clusters. Biomacromol, 17(6), 2293-301.
  11. Nam K, Maruyama CL, Trump BG, Buchmann L, Hunt JP, Monroe MM, Baker OJ (2016). Post-Irradiated Human Submandibular Glands Display High Collagen Deposition, Disorganized Cell Junctions, and an Increased Number of Adipocytes. J Histochem Cytochem, 64(6), 343-52.
  12. Wang CS, Wee Y, Yang CH, Melvin JE, Baker OJ (2016). ALX/FPR2 Modulates Anti-Inflammatory Responses in Mouse Submandibular Gland. Sci Rep, 6, 24244.
  13. Sommakia S, Baker OJ (2016). Neurons Self-Organize Around Salivary Epithelial Cells in Novel Co-Culture Model. 2(2).
  14. Maruyama CL, Leigh NJ, Nelson JW, McCall AD, Mellas RE, Lei P, Andreadis ST, Baker OJ (2015). Stem Cell-Soluble Signals Enhance Multilumen Formation in SMG Cell Clusters. J Dent Res, 94(11), 1610-7.
  15. McCall AD, Baker OJ (2015). Characterization of Angiogenesis and Lymphangiogenesis in Human Minor Salivary Glands with Sjögren's Syndrome. J Histochem Cytochem, 63(5), 340-9.
  16. Mellas RE, Kim H, Osinski J, Sadibasic S, Gronostajski RM, Cho M, Baker OJ (2015). NFIB regulates embryonic development of submandibular glands. J Dent Res, 94(2), 312-9.
  17. Easley JT, Nelson JW, Mellas RE, Sommakia S, Wu C, Trump B, Baker OJ (2015). Aspirin-Triggered Resolvin D1 Versus Dexamethasone in the Treatment of Sjögren's Syndrome-Like NOD/ShiLtJ Mice - A Pilot Study. 1(4).
  18. Mellas RE, Leigh NJ, Nelson JW, McCall AD, Baker OJ (2015). Zonula occludens-1, occludin and E-cadherin expression and organization in salivary glands with Sjögren's syndrome. J Histochem Cytochem, 63(1), 45-56.
  19. Baker OJ, Edgerton M, Kramer JM, Ruhl S (2014). Saliva-microbe interactions and salivary gland dysfunction. Adv Dent Res, 26(1), 7-14.
  20. Leigh NJ, Nelson JW, Mellas RE, Aguirre A, Baker OJ (2014). Expression of resolvin D1 biosynthetic pathways in salivary epithelium. J Dent Res, 93(3), 300-5.
  21. Nelson JW, Leigh NJ, Mellas RE, McCall AD, Aguirre A, Baker OJ (2014). ALX/FPR2 receptor for RvD1 is expressed and functional in salivary glands. Am J Physiol Cell Physiol, 306(2), C178-85.
  22. McCall AD, Nelson JW, Leigh NJ, Duffey ME, Lei P, Andreadis ST, Baker OJ (2013). Growth factors polymerized within fibrin hydrogel promote amylase production in parotid cells. Tissue Eng Part A, 19(19-20), 2215-25.
  23. Nelson J, Manzella K, Baker OJ (2013). Current cell models for bioengineering a salivary gland: a mini-review of emerging technologies. Oral Dis, 19(3), 236-44.
  24. Keinan D, Leigh NJ, Nelson JW, De Oleo L, Baker OJ (2013). Understanding resolvin signaling pathways to improve oral health. Int J Mol Sci, 14(3), 5501-18.
  25. Odusanwo O, Chinthamani S, McCall A, Duffey ME, Baker OJ (2012). Resolvin D1 prevents TNF-α-mediated disruption of salivary epithelial formation. Am J Physiol Cell Physiol, 302(9), C1331-45.
  26. Chinthamani S, Odusanwo O, Mondal N, Nelson J, Neelamegham S, Baker OJ (2012). Lipoxin A4 inhibits immune cell binding to salivary epithelium and vascular endothelium. Am J Physiol Cell Physiol, 302(7), C968-78.
  27. Baker OJ, Schulz DJ, Camden JM, Liao Z, Peterson TS, Seye CI, Petris MJ, Weisman GA (2010). Rat parotid gland cell differentiation in three-dimensional culture. Tissue Eng Part C Methods, 16(5), 1135-44.
  28. Ratchford AM, Baker OJ, Camden JM, Rikka S, Petris MJ, Seye CI, Erb L, Weisman GA (2010). P2Y2 nucleotide receptors mediate metalloprotease-dependent phosphorylation of epidermal growth factor receptor and ErbB3 in human salivary gland cells. J Biol Chem, 285(10), 7545-55.
  29. Baker OJ (2010). Tight junctions in salivary epithelium. J Biomed Biotechnol, 2010, 278948.
  30. Perry C, Baker OJ, Reyland ME, Grichtchenko II (2009). PKC{alpha}{beta}{gamma}- and PKC{delta}-dependent endocytosis of NBCe1-A and NBCe1-B in salivary parotid acinar cells. Am J Physiol Cell Physiol, 297(6), C1409-23.
  31. Baker OJ, Camden JM, Redman RS, Jones JE, Seye CI, Erb L, Weisman GA (2008). Proinflammatory cytokines tumor necrosis factor-alpha and interferon-gamma alter tight junction structure and function in the rat parotid gland Par-C10 cell line. Am J Physiol Cell Physiol, 295(5), C1191-201.
  32. Baker OJ, Camden JM, Rome DE, Seye CI, Weisman GA (2008). P2Y2 nucleotide receptor activation up-regulates vascular cell adhesion molecule-1 [corrected] expression and enhances lymphocyte adherence to a human submandibular gland cell line. Mol Immunol, 45(1), 65-75.
  33. Baker OJ, Camden JM, Ratchford AM, Seye CI, Erb L, Weisman GA (2006). Differential coupling of the P2Y1 receptor to Galpha14 and Galphaq/11 proteins during the development of the rat salivary gland. Arch Oral Biol, 51(5), 359-70.