Cornelia Ulrich, MS, PhD


  • English
  • German

Academic Information

  • Departments: Population Health Sciences - Professor
  • Divisions: Cancer Population Science

Academic Office Information

  • 801-213-5716
  • Primary Children’s and Families’ Cancer Research Center
    Population Health Sciences, Huntsman Cancer Institute
    2000 Circle of Hope, Room: 4725 (HCI Res South)
    Salt Lake City, UT 84112

Academic Bio

Jon M. and Karen Huntsman Presidential Professor in Cancer Research
Director, Comprehensive Cancer Center at Huntsman Cancer Institute

Professor, Department of Population Health Sciences, University of Utah

Dr. Cornelia Ulrich is a cancer epidemiologist whose research focuses on lifestyle and biologic factors in cancer prevention and cancer prognosis. She is a Jon M. and Karen Huntsman Presidential Professor in Cancer Research and Director of the Comprehensive Cancer Center at Huntsman Cancer Institute (HCI). Ulrich previously served as Senior Director of Population Sciences at HCI and as Division Chief of Cancer Population Sciences in the Department of Population Health Sciences at the University of Utah. She came to HCI from the German Cancer Research Center and National Center for Tumor Diseases, where she was Director, as well as Head of the Department of Preventive Oncology. As Senior Director, Dr. Ulrich oversaw the Utah Population Database, Genetic Counseling Shared Resource, Biostatistics Shared Resource, Biospecimen and Molecular Pathology Shared Resource, and the Utah Cancer Registry. Dr. Ulrich leads an interdisciplinary team of scientists on research related to the prevention, epidemiology, prognosis, and survivorship of cancer. Major research areas include personalized cancer prevention with aspirin or other anti-inflammatory drugs; nutrition; connections between obesity, adipose tissue, and the progression of cancer; cancer screening; and the role of energy balance and physical activity in cancer prevention and cancer survivorship. Dr. Ulrich is also Principal Investigator of the HCI of the Total Cancer Care Protocol in the ORIEN network of cancer centers.

In her role as Director of the Comprehensive Cancer Center at HCI, Ulrich serves as principal investigator of HCI's Cancer Center Support Grant (CCSG).

Dr. Ulrich has authored more than 350 publications, including the book "Exercise, Energy Balance, and Cancer". She has served as PI of 23 active or completed funded projects, including a U01, nine R01 grants that involve multiple institutions, one R21, four R03s, one U54 Project PI, and seven European grants. Since 2001, she has been funded as PI of either NIH grants or awards made through the equivalent German and European granting organizations. She is an elected member to the European Academy of Cancer Sciences, and serves on numerous national and international advisory boards, committees, and editorial boards, including several of the National Institutes of Health, National Academies of Sciences, Engineering and Medicine, International Agency for Research on Cancer, and American Association of Cancer Research.

Research Statement

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Education History

Type School Degree
Doctoral Training University of Washington
Post Graduate Training University of Washington
Doctoral Studies Program: Health Services Research
Graduate Training Oregon State University
Nutrition, Minor: Public Health
Undergraduate University of Hohenheim
Nutrition Science

Global Impact

Education History

Type School Degree Country
Undergraduate University of Hohenheim
Nutrition Science
B.S. Germany

Selected Publications

Journal Article

  1. Zhang P, Holowatyj AN, Ulrich CM, Edgar BA (2019). Tumor suppressive autophagy in intestinal stem cells controls gut homeostasis. Autophagy, 15(9), 1668-1670.
  2. Geijsen AJMR, Brezina S, Keski-Rahkonen P, Baierl A, Bachleitner-Hofmann T, Bergmann MM, Boehm J, Brenner H, Chang-Claude J, van Duijnhoven FJB, Gigic B, Gumpenberger T, Hofer P, Hoffmeister M, Holowatyj AN, Karner-Hanusch J, Kok DE, Leeb G, Ulvik A, Robinot N, Ose J, Stift A, Schrotz-King P, Ulrich AB, Ueland PM, Kampman E, Scalbert A, Habermann N, Gsur A, Ulrich CM (2019). Plasma metabolites associated with colorectal cancer: A discovery-replication strategy. Int J Cancer, 145(5), 1221-1231.
  3. Holowatyj AN, Lewis MA, Pannier ST, Kirchhoff AC, Hardikar S, Figueiredo JC, Huang LC, Shibata D, Schmit SL, Ulrich CM (2019). Clinicopathologic and Racial/Ethnic Differences of Colorectal Cancer Among Adolescents and Young Adults. Clin Transl Gastroenterol, 10(7), e00059.
  4. Himbert C, Ose J, Lin T, Warby CA, Gigic B, Steindorf K, Schrotz-King P, Abbenhardt-Martin C, Zielske L, Boehm J, Ulrich CM (2019). Inflammation- and angiogenesis-related biomarkers are correlated with cancer-related fatigue in colorectal cancer patients: Results from the ColoCare Study. Eur J Cancer Care (Engl), 28(4), e13055.
  5. Haffa M, Lin T, Holowatyj AN, Kratz M, Toth R, Benner A, Gigic B, Habermann N, Schrotz-King P, Bhm J, Brenner H, Schneider M, Ulrich A, Herpel E, Schirmacher P, Straub BK, Nattenmller J, Kauczor HU, Ball CR, Ulrich CM, Glimm H, Scherer D (2019). Transcriptome profiling of adipose tissue reveals depot-specific metabolic alterations among colorectal cancer patients. (Epub ahead of print) J Clin Endocrinol Metab.
  6. Yu B, Zanetti KA, Temprosa M, Albanes D, Appel N, Barrera CB, Ben-Shlomo Y, Boerwinkle E, Casas JP, Clish C, Dale C, Dehghan A, Derkach A, Eliassen AH, Elliott P, Fahy E, Gieger C, Gunter MJ, Harada S, Harris T, Herr DR, Herrington D, Hirschhorn JN, Hoover E, Hsing AW, Johansson M, Kelly RS, Khoo CM, Kivimki M, Kristal BS, Langenberg C, Lasky-Su J, Lawlor DA, Lotta LA, Mangino M, Le Marchand L, Math E, Matthews CE, Menni C, Mucci LA, Murphy R, Oresic M, Orwoll E, Ose J, Pereira AC, Playdon MC, Poston L, Price J, Qi Q, Rexrode K, Risch A, Sampson J, Seow WJ, Sesso HD, Shah SH, Shu XO, Smith GCS, Sovio U, Stevens VL, Stolzenberg-Solomon R, Takebayashi T, Tillin T, Travis R, Tzoulaki I, Ulrich CM, Vasan RS, Verma M, Wang Y, Wareham NJ, Wong A, Younes N, Zhao H, Zheng W, Moore SC (2018). The Consortium of Metabolomics Studies (COMETS): Metabolomics in 47 Prospective Cohort Studies. Am J Epidemiol, 188(6), 991-1012.
  7. Zhang P, Holowatyj AN, Roy T, Pronovost SM, Marchetti M, Liu H, Ulrich CM, Edgar BA (2019). An SH3PX1-Dependent Endocytosis-Autophagy Network Restrains Intestinal Stem Cell Proliferation by Counteracting EGFR-ERK Signaling. Dev Cell, 49(4), 574-589.e5.
  8. Jiang Y, Spurny M, Schbel R, Nonnenmacher T, Schlett CL, von Stackelberg O, Ulrich CM, Kaaks R, Kauczor HU, Khn T, Nattenmller J (2019). Changes in Pancreatic Fat Content Following Diet-Induced Weight Loss. Nutrients, 11(4).
  9. Wirbel J, Pyl PT, Kartal E, Zych K, Kashani A, Milanese A, Fleck JS, Voigt AY, Palleja A, Ponnudurai R, Sunagawa S, Coelho LP, Schrotz-King P, Vogtmann E, Habermann N, Nimus E, Thomas AM, Manghi P, Gandini S, Serrano D, Mizutani S, Shiroma H, Shiba S, Shibata T, Yachida S, Yamada T, Waldron L, Naccarati A, Segata N, Sinha R, Ulrich CM, Brenner H, Arumugam M, Bork P, Zeller G (2019). Meta-analysis of fecal metagenomes reveals global microbial signatures that are specific for colorectal cancer. Nat Med, 25(4), 679-689.
  10. Thomas AM, Manghi P, Asnicar F, Pasolli E, Armanini F, Zolfo M, Beghini F, Manara S, Karcher N, Pozzi C, Gandini S, Serrano D, Tarallo S, Francavilla A, Gallo G, Trompetto M, Ferrero G, Mizutani S, Shiroma H, Shiba S, Shibata T, Yachida S, Yamada T, Wirbel J, Schrotz-King P, Ulrich CM, Brenner H, Arumugam M, Bork P, Zeller G, Cordero F, Dias-Neto E, Setubal JC, Tett A, Pardini B, Rescigno M, Waldron L, Naccarati A, Segata N (2019). Metagenomic analysis of colorectal cancer datasets identifies cross-cohort microbial diagnostic signatures and a link with choline degradation. Nat Med, 25(4), 667-678.
  11. Bien SA, Su YR, Conti DV, Harrison TA, Qu C, Guo X, Lu Y, Albanes D, Auer PL, Banbury BL, Berndt SI, Bzieau S, Brenner H, Buchanan DD, Caan BJ, Campbell PT, Carlson CS, Chan AT, Chang-Claude J, Chen S, Connolly CM, Easton DF, Feskens EJM, Gallinger S, Giles GG, Gunter MJ, Hampe J, Huyghe JR, Hoffmeister M, Hudson TJ, Jacobs EJ, Jenkins MA, Kampman E, Kang HM, Khn T, Kry S, Lejbkowicz F, Le Marchand L, Milne RL, Li L, Li CI, Lindblom A, Lindor NM, Martn V, McNeil CE, Melas M, Moreno V, Newcomb PA, Offit K, Pharaoh PDP, Potter JD, Qu C, Riboli E, Rennert G, Sala N, Schafmayer C, Scacheri PC, Schmit SL, Severi G, Slattery ML, Smith JD, Trichopoulou A, Tumino R, Ulrich CM, van Duijnhoven FJB, Van Guelpen B, Weinstein SJ, White E, Wolk A, Woods MO, Wu AH, Abecasis GR, Casey G, Nickerson DA, Gruber SB, Hsu L, Zheng W, Peters U (2019). Genetic variant predictors of gene expression provide new insight into risk of colorectal cancer. Hum Genet, 138(4), 307-326.
  12. Schbel R, Sookthai D, Greimel J, Johnson TS, Grafetsttter ME, Kirsten R, Kratz M, Ulrich CM, Kaaks R, Khn T (2019). Key Genes of Lipid Metabolism and WNT-Signaling Are Downregulated in Subcutaneous Adipose Tissue with Moderate Weight Loss. Nutrients, 11(3).
  13. Schbel R, Nonnenmacher T, Sookthai D, Gonzalez Maldonado S, Sowah SA, von Stackelberg O, Schlett CL, Grafetsttter M, Nabers D, Johnson T, Kirsten R, Ulrich CM, Kaaks R, Kauczor HU, Khn T, Nattenmller J (2019). Similar Weight Loss Induces Greater Improvements in Insulin Sensitivity and Liver Function among Individuals with NAFLD Compared to Individuals without NAFLD. Nutrients, 11(3).
  14. Ulrich CM, Gigic B, Bhm J, Ose J, Viskochil R, Schneider M, Colditz GA, Figueiredo JC, Grady WM, Li CI, Shibata D, Siegel EM, Toriola AT, Ulrich A (2018). The ColoCare Study: A Paradigm of Transdisciplinary Science in Colorectal Cancer Outcomes. Cancer Epidemiol Biomarkers Prev, 28(3), 591-601.
  15. Lagergren P, Schandl A, Aaronson NK, Adami HO, de Lorenzo F, Denis L, Faithfull S, Liu L, Meunier F, Ulrich C, European Academy of Cancer Sciences (2019). Cancer survivorship: an integral part of Europe's research agenda. Mol Oncol, 13(3), 624-635.
  16. Luebeck GE, Hazelton WD, Curtius K, Maden SK, Yu M, Carter KT, Burke W, Lampe PD, Li CI, Ulrich CM, Newcomb PA, Westerhoff M, Kaz AM, Luo Y, Inadomi JM, Grady WM (2018). Implications of Epigenetic Drift in Colorectal Neoplasia. Cancer Res, 79(3), 495-504.
  17. Himbert C, Ose J, Nattenmller J, Warby CA, Holowatyj AN, Bhm J, Lin T, Haffa M, Gigic B, Hardikar S, Scherer D, Zielske L, Schrotz-King P, Klsch T, Siegel EM, Shibata D, Ulrich A, Schneider M, Hursting SD, Kauczor HU, Ulrich CM (2018). Body Fatness, Adipose Tissue Compartments, and Biomarkers of Inflammation and Angiogenesis in Colorectal Cancer: The ColoCare Study. Cancer Epidemiol Biomarkers Prev, 28(1), 76-82.
  18. Huyghe JR, Bien SA, Harrison TA, Kang HM, Chen S, Schmit SL, Conti DV, Qu C, Jeon J, Edlund CK, Greenside P, Wainberg M, Schumacher FR, Smith JD, Levine DM, Nelson SC, Sinnott-Armstrong NA, Albanes D, Alonso MH, Anderson K, Arnau-Collell C, Arndt V, Bamia C, Banbury BL, Baron JA, Berndt SI, Bzieau S, Bishop DT, Boehm J, Boeing H, Brenner H, Brezina S, Buch S, Buchanan DD, Burnett-Hartman A, Butterbach K, Caan BJ, Campbell PT, Carlson CS, Castellv-Bel S, Chan AT, Chang-Claude J, Chanock SJ, Chirlaque MD, Cho SH, Connolly CM, Cross AJ, Cuk K, Curtis KR, de la Chapelle A, Doheny KF, Duggan D, Easton DF, Elias SG, Elliott F, English DR, Feskens EJM, Figueiredo JC, Fischer R, FitzGerald LM, Forman D, Gala M, Gallinger S, Gauderman WJ, Giles GG, Gillanders E, Gong J, Goodman PJ, Grady WM, Grove JS, Gsur A, Gunter MJ, Haile RW, Hampe J, Hampel H, Harlid S, Hayes RB, Hofer P, Hoffmeister M, Hopper JL, Hsu WL, Huang WY, Hudson TJ, Hunter DJ, Ibaez-Sanz G, Idos GE, Ingersoll R, Jackson RD, Jacobs EJ, Jenkins MA, Joshi AD, Joshu CE, Keku TO, Key TJ, Kim HR, Kobayashi E, Kolonel LN, Kooperberg C, Khn T, Kry S, Kweon SS, Larsson SC, Laurie CA, Le Marchand L, Leal SM, Lee SC, Lejbkowicz F, Lemire M, Li CI, Li L, Lieb W, Lin Y, Lindblom A, Lindor NM, Ling H, Louie TL, Mnnist S, Markowitz SD, Martn V, Masala G, McNeil CE, Melas M, Milne RL, Moreno L, Murphy N, Myte R, Naccarati A, Newcomb PA, Offit K, Ogino S, Onland-Moret NC, Pardini B, Parfrey PS, Pearlman R, Perduca V, Pharoah PDP, Pinchev M, Platz EA, Prentice RL, Pugh E, Raskin L, Rennert G, Rennert HS, Riboli E, Rodrguez-Barranco M, Romm J, Sakoda LC, Schafmayer C, Schoen RE, Seminara D, Shah M, Shelford T, Shin MH, Shulman K, Sieri S, Slattery ML, Southey MC, Stadler ZK, Stegmaier C, Su YR, Tangen CM, Thibodeau SN, Thomas DC, Thomas SS, Toland AE, Trichopoulou A, Ulrich CM, Van Den Berg DJ, van Duijnhoven FJB, Van Guelpen B, van Kranen H, Vijai J, Visvanathan K, Vodicka P, Vodickova L, Vymetalkova V, Weigl K, Weinstein SJ, White E, Win AK, Wolf CR, Wolk A, Woods MO, Wu AH, Zaidi SH, Zanke BW, Zhang Q, Zheng W, Scacheri PC, Potter JD, Bassik MC, Kundaje A, Casey G, Moreno V, Abecasis GR, Nickerson DA, Gruber SB, Hsu L, Peters U (2018). Discovery of common and rare genetic risk variants for colorectal cancer. Nat Genet, 51(1), 76-87.
  19. Ulrich CM, Himbert C, Boucher K, Wetter DW, Hess R, Kim J, Lundberg K, Ligibel JA, Barnes CA, Rushton B, Marcus R, Finlayson SRG, LaStayo PC, Varghese TK (2018). Precision-Exercise-Prescription in patients with lung cancer undergoing surgery: rationale and design of the PEP study trial. BMJ Open, 8(12), e024672.
  20. Kok DE, Steegenga WT, Smid EJ, Zoetendal EG, Ulrich CM, Kampman E (2018). Bacterial folate biosynthesis and colorectal cancer risk: more than just a gut feeling. Crit Rev Food Sci Nutr, 1-13.
  21. Schbel R, Nattenmller J, Sookthai D, Nonnenmacher T, Graf ME, Riedl L, Schlett CL, von Stackelberg O, Johnson T, Nabers D, Kirsten R, Kratz M, Kauczor HU, Ulrich CM, Kaaks R, Khn T (2017). Effects of intermittent and continuous calorie restriction on body weight and metabolism over 50 wk: a randomized controlled trial. Am J Clin Nutr, 108(5), 933-945.
  22. Brixner DI, Stenehjem DD, Ulrich C (2016). Aspirin and Cancer Risk. JAMA Oncol, 2(10), 1370-1371.
  23. Samadder NJ, Curtin K, Pappas L, Boucher K, Mineau GP, Smith K, Fraser A, Wan Y, Provenzale D, Kinney AY, Ulrich C, Burt RW (2015). Risk of Incident Colorectal Cancer and Death After Colonoscopy: A Population-based Study in Utah. Clin Gastroenterol Hepatol, 14(2), 279-86.e1-2.