Jacob Kean

Jacob Kean, PhD

Languages spoken: English

Academic Information

Departments Primary - Population Health Sciences , Adjunct - Biomedical Informatics , Adjunct - Internal Medicine

Divisions: Epidemiology , Epidemiology

Academic Office Information

Jacob.Kean@hsc.utah.edu

Jacob Kean, PhD, is an Associate Professor in Health System Innovation and Research, Department of Population Health Sciences, University of Utah, and Research Scientist, Salt Lake City VA Health Care System. He completed his doctorate in 2008 and served subsequently and concurrent with his faculty appointments at Indiana University as an Indiana CTSI KL2 Faculty Scholar, a Visiting Scientist at the Boston University Rehabilitation Outcomes Center, a Visiting Scholar at the Center for Rehabilitation Research Using Large Datasets at the University of Texas Medical Branch, and a VA Career Development Awardee. Dr. Kean completed the NIH Training Institute for Dissemination and Implementation Research in Health (TIDIRH) and a post-doctoral Master’s degree in Measurement, Evaluation, Statistics and Assessment (MESA) at the University of Illinois – Chicago.

Dr. Kean’s expertise lies at the nexus of these training areas: the creation and operation of research networks and the evaluation of network care practices using patient-centered outcomes. He is the Director of the Population Health Science – U Health Learning Health System, Principal Investigator of the Cerebral Palsy Research Network Data Coordinating Center, PI of the DoD-funded Optimizing Rehabilitation InterventiONs (ORION) for Cognition Following Complex Traumatic Brain Injury network, and Co-PI of the VA-funded Brain Injury Data Sharing Project, all of which are EHR-based learning health systems focused primarily on the care of persons with acquired neurological disorders.

Education History

Other Training Center for Rehabilitation Research Using Large Datasets, University of Texas Medical Branch
 Visiting Scholar
NIH Training Institute for Dissemination and Implementation Research in Health (TIDIRH)
 Visiting Scholar
Graduate Training University of Illinois
 MEd
Health & Disability Research Institute, Boston University School of Public Health
 Visiting Scholar
Fellowship Massachusetts General Hospital
 Visiting Fellow
Rehabilitation Hospital of Indiana
 Predoctoral Research Fellow
Doctoral Training Indiana University Bloomington
 PhD
Indiana University Bloomington
 MA
Undergraduate Ball State University
 BS
Undergraduate Purdue University

Selected Publications

Journal Article

  1. Kroenke K, Stump TE, Chen CX, Kean J, Bair MJ, Damush TM, Krebs EE, Monahan PO (2020). Minimally important differences and severity thresholds are estimated for the PROMIS depression scales from three randomized clinical trials. J Affect Disord, 266, 100-108.
  2. Kroenke K, Stump TE, Kean J, Talib TL, Haggstrom DA, Monahan PO (2019). PROMIS 4-item measures and numeric rating scales efficiently assess SPADE symptoms compared with legacy measures. J Clin Epidemiol, 115, 116-124.
  3. Franco JG, Ocampo MV, Velsquez-Tirado JD, Zaraza DR, Giraldo AM, Serna PA, Lpez C, Zuluaga A, Seplveda E, Kean J, Trzepacz PT (2019). Validation of the Delirium Diagnostic Tool-Provisional (DDT-Pro) With Medical Inpatients and Comparison With the Confusion Assessment Method Algorithm. J Neuropsychiatry Clin Neurosci, appineuropsych18110255.
  4. Talib TL, DeChant P, Kean J, Monahan PO, Haggstrom DA, Stout ME, Kroenke K (2018). A qualitative study of patients' perceptions of the utility of patient-reported outcome measures of symptoms in primary care clinics. Qual Life Res, 27(12), 3157-3166.
  5. Gross PH, Bailes AF, Horn SD, Hurvitz EA, Kean J, Shusterman M (2018). Setting a patient-centered research agenda for cerebral palsy: a participatory action research initiative. Dev Med Child Neurol, 60(12), 1278-1284.
  6. Trzepacz PT, Franco JG, Meagher DJ, Lee Y, Kim JL, Kishi Y, Furlanetto LM, Negreiros D, Huang MC, Chen CH, Kean J, Leonard M (2018). Delirium Phenotype by Age and Sex in a Pooled Data Set of Adult Patients. J Neuropsychiatry Clin Neurosci, 30(4), 294-301.
  7. Kroenke K, Talib TL, Stump TE, Kean J, Haggstrom DA, DeChant P, Lake KR, Stout M, Monahan PO (2018). Incorporating PROMIS Symptom Measures into Primary Care Practice-a Randomized Clinical Trial. J Gen Intern Med, 33(8), 1245-1252.
  8. Chen CX, Kroenke K, Stump TE, Kean J, Carpenter JS, Krebs EE, Bair MJ, Damush TM, Monahan PO (2018). Estimating minimally important differences for the PROMIS pain interference scales: results from 3 randomized clinical trials. Pain, 159(4), 775-782.
  9. Kean J, Brodke DS, Biber J, Gross P (2018). An introduction to Item Response Theory and Rasch Analysis of the Eating Assessment Tool (EAT-10). Brain Impair, 19(Spec Iss 1), 91-102.
  10. Malec JF, Stump TE, Monahan PO, Kean J, Neumann D, Hammond FM (2018). Rasch Analysis, Dimensionality, and Scoring of the Neuropsychiatric Inventory Irritability and Aggression Subscales in Individuals With Traumatic Brain Injury. Arch Phys Med Rehabil, 99(2), 281-288.e2.
  11. Eliacin J, Fortney S, Rattray NA, Kean J (2018). Access to health services for moderate to severe TBI in Indiana: patient and caregiver perspectives. Brain Inj, 32(12), 1510-1517.
  12. Malec JF, Kean J, Monahan PO (2017). The Minimal Clinically Important Difference for the Mayo-Portland Adaptability Inventory. J Head Trauma Rehabil, 32(4), E47-E54.
  13. Witkin LR, Zylberger D, Mehta N, Hindenlang M, Johnson C, Kean J, Horn SD, Inturrisi CE (2017). Patient-Reported Outcomes and Opioid Use in Outpatients With Chronic Pain. J Pain, 18(5), 583-596.
  14. Presson AP, Zhang C, Abtahi AM, Kean J, Hung M, Tyser AR (2017). Psychometric properties of the Press Ganey® Outpatient Medical Practice Survey. Health Qual Life Outcomes, 15(1), 32.
  15. Ash AC, Redmond SM, Timler GR, Kean J (2017). The influence of scale structure and sex on parental reports of children's social (pragmatic) communication symptoms. Clin Linguist Phon, 31(4), 293-312.
  16. Rahurkar S, McFarlane TD, Wang J, Hoover S, Hammond F, Kean J, Dixon BE (2017). Leveraging Health Information Exchange to Construct a Registry for Traumatic Brain Injury, Spinal Cord Injury and Stroke in Indiana. AMIA Annu Symp Proc, 2017, 1440-1449.
  17. Wambaugh J, Shuster L, Bailey DJ, Mauszycki S, Kean J, Nessler C, Wright S, Brunsvold J (2016). Self-Judgments of Word Production Accuracy in Acquired Apraxia of Speech. Am J Speech Lang Pathol, 25(4S), S716-S728.
  18. Pretz CR, Kean J, Heinemann AW, Kozlowski AJ, Bode RK, Gebhardt E (2016). A Multidimensional Rasch Analysis of the Functional Independence Measure Based on the National Institute on Disability, Independent Living, and Rehabilitation Research Traumatic Brain Injury Model Systems National Database. J Neurotrauma, 33(14), 1358-62.
  19. Malec JF, Kean J (2016). Post-Inpatient Brain Injury Rehabilitation Outcomes: Report from the National OutcomeInfo Database. J Neurotrauma, 33(14), 1371-9.
  20. Kroenke K, Wu J, Yu Z, Bair MJ, Kean J, Stump T, Monahan PO (2016). Patient Health Questionnaire Anxiety and Depression Scale: Initial Validation in Three Clinical Trials. Psychosom Med, 78(6), 716-27.
  21. Davis LL, Kroenke K, Monahan P, Kean J, Stump TE (2016). The SPADE Symptom Cluster in Primary Care Patients With Chronic Pain. Clin J Pain, 32(5), 388-93.
  22. Kean J, Monahan PO, Kroenke K, Wu J, Yu Z, Stump TE, Krebs EE (2016). Comparative Responsiveness of the PROMIS Pain Interference Short Forms, Brief Pain Inventory, PEG, and SF-36 Bodily Pain Subscale. Med Care, 54(4), 414-21.
  23. McGuire AB, Salyers MP, White DA, Gilbride DJ, White LM, Kean J, Kukla M (2015). Factors affecting implementation of an evidence-based practice in the Veterans Health Administration: Illness management and recovery. Psychiatr Rehabil J, 38(4), 300-5.
  24. Kroenke K, Monahan PO, Kean J (2015). Pragmatic characteristics of patient-reported outcome measures are important for use in clinical practice. J Clin Epidemiol, 68(9), 1085-92.
  25. Thurber S, Kishi Y, Trzepacz PT, Franco JG, Meagher DJ, Lee Y, Kim JL, Furlanetto LM, Negreiros D, Huang MC, Chen CH, Kean J, Leonard M (2015). Confirmatory Factor Analysis of the Delirium Rating Scale Revised-98 (DRS-R98). J Neuropsychiatry Clin Neurosci, 27(2), e122-7.
  26. Kroenke K, Yu Z, Wu J, Kean J, Monahan PO (2014). Operating characteristics of PROMIS four-item depression and anxiety scales in primary care patients with chronic pain. Pain Med, 15(11), 1892-901.
  27. McGuire AB, Kean J, Bonfils K, Presnell J, Salyers MP (2014). Rasch analysis of the illness management and recovery scale-clinician version. J Eval Clin Pract, 20(4), 383-9.
  28. Van Puymbroeck M, Altenberger P, Combs S, Miller K, Kean J, Williams L, Schmid AA (2014). The influence of mood related variables on activity and participation in individuals with chronic stroke. Top Geriatr Rehabil, 30(3), 216-22.
  29. Kean J, Malec JF, Cooper DB, Bowles AO (2013). Utility of the Mayo-Portland adaptability inventory-4 for self-reported outcomes in a military sample with traumatic brain injury. Arch Phys Med Rehabil, 94(12), 2417-24.
  30. Malec JF, Hammond FM, Flanagan S, Kean J, Sander A, Sherer M, Masel BE (2013). Recommendations from the 2013 Galveston Brain Injury Conference for implementation of a chronic care model in brain injury. J Head Trauma Rehabil, 28(6), 476-83.
  31. Salyers MP, Brennan M, Kean J (2013). Provider Expectations for Recovery Scale: refining a measure of provider attitudes. Psychiatr Rehabil J, 36(3), 153-9.
  32. Miller KK, Combs SA, Van Puymbroeck M, Altenburger PA, Kean J, Dierks TA, Schmid AA (2013). Fatigue and pain: relationships with physical performance and patient beliefs after stroke. Top Stroke Rehabil, 20(4), 347-55.
  33. Franco JG, Trzepacz PT, Meagher DJ, Kean J, Lee Y, Kim JL, Kishi Y, Furlanetto LM, Negreiros D, Huang MC, Chen CH, Leonard M, de Pablo J (2013). Three core domains of delirium validated using exploratory and confirmatory factor analyses. Psychosomatics, 54(3), 227-38.
  34. Trzepacz PT, Franco JG, Meagher DJ, Lee Y, Kim JL, Kishi Y, Furlanetto LM, Negreiros D, Huang MC, Chen CH, Kean J, Leonard M (2012). Phenotype of subsyndromal delirium using pooled multicultural Delirium Rating Scale--Revised-98 data. J Psychosom Res, 73(1), 10-7.
  35. Reilly J, Westbury C, Kean J, Peelle JE (2012). Arbitrary symbolism in natural language revisited: when word forms carry meaning. PLoS One, 7(8), e42286.
  36. Malec JF, Kean J, Altman IM, Swick S (2012). Comparative Psychometric Analysis of the Mayo-Portland Adaptability Inventory (MPAI-4) in Patients with Cerebrovascular Accident and Traumatic Brain Injury. Arch Phys Med Rehabil, 93(12), 2271-5.
  37. Kean J, Abell M, Malec JF, Trzepacz PT (2011). Rasch analysis of the orientation log and reconsideration of the latent construct during inpatient rehabilitation. J Head Trauma Rehabil, 26(5), 364-74.
  38. Scott PJ, Altenburger PA, Kean J (2011). A collaborative teaching strategy for enhancing learning of evidence-based clinical decision-making. J Allied Health, 40(3), 120-7.
  39. Kean J, Malec JF, Altman IM, Swick S (2011). Rasch measurement analysis of the Mayo-Portland Adaptability Inventory (MPAI-4) in a community-based rehabilitation sample. J Neurotrauma, 28(5), 745-53.
  40. Seel RT, Sherer M, Whyte J, Katz DI, Giacino JT, Rosenbaum AM, Hammond FM, Kalmar K, Pape TL, Zafonte R, Biester RC, Kaelin D, Kean J, Zasler N (2010). Assessment scales for disorders of consciousness: evidence-based recommendations for clinical practice and research. Arch Phys Med Rehabil, 91(12), 1795-813.
  41. Kean J, Trzepacz PT, Murray LL, Abell M, Trexler L (2010). Initial validation of a brief provisional diagnostic scale for delirium. Brain Inj, 24(10), 1222-30.
  42. Kean J, Ryan K (2008). Delirium detection in clinical practice and research: critique of current tools and suggestions for future development. J Psychosom Res, 65(3), 255-9.
  43. Kean J, Locke DEC (2008). Neuropsychological consequences of cancer and cancer treatment. Perspect Neurophysiol Neurogenic Speech Lang Disord, 18(4), 144-51.
  44. Reilly J, Kean J (2007). Formal distinctiveness of high- and low-imageability nouns: analyses and theoretical implications. Cogn Sci, 31(1), 157-68.
  45. Murray LL, Kean J (2004). Resource theory and aphasia: Time to abandon or time to revise? Aphasiology, 18(3), 830-35.

Book Chapter

  1. Stevens, K R, Horn, S D, Kean, J, Deshmukh, V G, Mitchell, S A, amp Nelson, R (2018). Evidence-Based Practice, Practice-Based Evidence, and Health Informatics. In R. Nelson & N. Staggers (Eds.), Evidence-Based Practice, Practice-Based Evidence, and Health Informatics (2nd). St Louis, MO: Mosby.
  2. Kean, J, Bowles, AO, Cooper, DB, McGuire, AB (2015). Implementation of the SCORE clinical trial in DoD and VA Healthcare settings: Administrative Considerations and Fidelity Tools. In The Study of Cognitive Rehabilitation Effectiveness.
  3. Kean J, Reilly J (2014). Item Response Theory. In Hammond FM, Malec JF, Nick TG, Buschbacher RM (Eds.), Handbook for Clinical Research: Design, Statistics, and Implementation (pp. 195-7). New York: Demos Medical.
  4. Kean J, Reilly J (2014). Classical Test Theory. In Hammond FM, Malec JF, Nick TG, Buschbacher RM (Eds.), Handbook for Clinical Research: Design, Statistics, and Implementation (pp. 192-4). New York: Demos Medical.
  5. McDonald BC, Kean J, Saykin AJ (2012). fMRI Wada test: prospects for presurgical mapping of language and memory. In Faro SH, Mohamed FB (Eds.), Functional Neuroradiology (pp. 455-84). New York: Springer.
  6. Trzepacz PT, Kean J, Kennedy RE (2011). Delirium and posttraumatic confusion. In Silver JM, McAllister TW, Yudofsky SC (Eds.), Textbook of Traumatic Brain Injury (2nd Edition). Arlington: American Psychiatric Publishing, Inc.

Conference Proceedings

  1. Abell M, Kean J, Trzepacz P, Meagher D (2011). Poster 119 Delirium Phenomenology In TBI Rehabilitation and Palliative Care Cohorts Using Factor Analysis of the DRS-R98. Bloomington, IN: Archives of Physical Medicine and Rehabilitation., 92(10), 1726.
  2. Kean J, Malec J, Cooper D, Bowles A (2011). Poster 101 Utility of the MPAI-4 for Self-Reported Outcomes in a Military Sample With TBI. Indianapolis, IN: Archives of Physical Medicine and Rehabilitation, 92(10), 1721.
  3. Cappa K, Kean J, Parrott D, Abell M (2010). Poster 27: Prognostic Significance of Motor Subtype During Acute Recovery From Traumatic Brain Injury. Archives of Physical Medicine and Rehabilitation, 92(10), e12.
  4. Parrott D, Kean J, Malene A, Cappa K, Williams M (2010). Poster 23: Fluctuations in Performance on the Orientation Log During Acute Recovery Predict Functional Status at Discharge Following Traumatic Brain Injury. Indianapolis, IN: Archives of Physical Medicine and Rehabilitation, 91(10), e11.
  5. Parrott D, Kean J, Malene A, Cappa K, Williams M (2010). Poster 162: Fluctuations in Performance on the Orientation Log During Acute Recovery Predict Functional Status at Discharge Following Traumatic Brain Injury. Indianapolis, IN: Archives of Physical Medicine and Rehabilitation., 91(10), e54.
  6. Abell M, Kean J, Malec J (2009). Poster 22: Further Investigation of Resolution of the Acute Confusion (delirium) in the Acute Period Following Traumatic Brain Injury. Indianapolis, IN: Archives of Physical Medicine and Rehabilitation, 90(10), e18.
  7. Kean J, Abell M, Trzepacz P (2009). Article 12: Identification of the Duration of Post-traumatic Amnesia Using Measures of Orientation and Delirium. Bloomington, IN: Archives of Physical Medicine and Rehabilitation, 90(10), e6.
  8. Holder MA, Kean J, Trzepacz P, Malec J, Neal-Beliveau B, Williams J (2008). Poster 9: Anticholinergic Drugs and Severity of Post-Brain Injury Delirium. Indianapolis, IN: Archives of Physical Medicine and Rehabilitation, 89(10), e30-e31.
  9. Kean J, Trzepacz P, Murray L, Trexler L, Holder MA (2008). Poster 3: Detection of Delirium (Posttraumatic Acute Confusion) in Acquired Brain Injury. Bloomington, IN: Archives of Physical Medicine and Rehabilitation, 89(10), e29.

Editorial

  1. Kean J, Malec JF (2014). Towards a better measure of brain injury outcome: new measures or a new metric? Arch Phys Med Rehabil, 95(7), 1225-8.

Letter

  1. Reilly J, Kean J (2011). Information content and word frequency in natural language: word length matters. [Letter to the editor]. Proc Natl Acad Sci U S A, 108(20), E108; author reply E109.