Bhagirath Chaurasia, MS, PhD

Academic Information

  • Departments: Nutrition and Integrative Physiology - Research Assistant Professor

Selected Publications

Journal Article

  1. Chaurasia B, Kaddai VA, Lancaster GI, Henstridge DC, Sriram S, Galam DL, Gopalan V, Prakash KN, Velan SS, Bulchand S, Tsong TJ, Wang M, Siddique MM, Yuguang G, Sigmundsson K, Mellet NA, Weir JM, Meikle PJ, Bin M Yassin MS, Shabbir A, Shayman JA, Hirabayashi Y, Shiow ST, Sugii S, Summers SA (2016). Adipocyte Ceramides Regulate Subcutaneous Adipose Browning, Inflammation, and Metabolism. Cell Metab, 24(6), 820-834.
  2. Jais A, Solas M, Backes H, Chaurasia B, Kleinridders A, Theurich S, Mauer J, Steculorum SM, Hampel B, Goldau J, Alber J, Forster CY, Eming SA, Schwaninger M, Ferrara N, Karsenty G, Bruning JC (2016). Myeloid-Cell-Derived VEGF Maintains Brain Glucose Uptake and Limits Cognitive Impairment in Obesity. Cell, 166(5), 1338-1340.
  3. Jais A, Solas M, Backes H, Chaurasia B, Kleinridders A, Theurich S, Mauer J, Steculorum SM, Hampel B, Goldau J, Alber J, Forster CY, Eming SA, Schwaninger M, Ferrara N, Karsenty G, Bruning JC (2016). Myeloid-Cell-Derived VEGF Maintains Brain Glucose Uptake and Limits Cognitive Impairment in Obesity. Cell, 165(4), 882-95.
  4. Raichur S, Wang ST, Chan PW, Li Y, Ching J, Chaurasia B, Dogra S, Ohman MK, Takeda K, Sugii S, Pewzner-Jung Y, Futerman AH, Summers SA (2014). CerS2 haploinsufficiency inhibits beta-oxidation and confers susceptibility to diet-induced steatohepatitis and insulin resistance. Cell Metab, 20(4), 687-95.
  5. Mauer J, Chaurasia, B, Goldau J, Vogt M, Ruud J, Nguyen K, Theurich S, Hausen C, Schmitz J, Brnneke H, Estevez E, Allen T, Mesaros A, Partridge L, Febbraio M, Chawla A, Wnderlich T amp Brning J (05/01/2014). Signalling by IL-6 promotes alternative activation of macrophages to limit endotoxemia and obesity-associated resistance to insulin. Nat Immunol, 15(5), 423-30.
  6. Wunderlich CM, Delic D, Behnke K, Meryk A, Strohle P, Chaurasia B, Al-Quraishy S, Wunderlich F, Bruning JC, Wunderlich FT (2012). Cutting edge: Inhibition of IL-6 trans-signaling protects from malaria-induced lethality in mice. J Immunol, 188(9), 4141-4.
  7. Chaurasia B, Mauer J, Koch L, Goldau J, Kock AS, Bruning JC (2010). Phosphoinositide-dependent kinase 1 provides negative feedback inhibition to Toll-like receptor-mediated NF-kappaB activation in macrophages. Mol Cell Biol, 30(17), 4354-66.
  8. Mauer J, Chaurasia B, Plum L, Quast T, Hampel B, Bluher M, Kolanus W, Kahn CR, Bruning JC (2010). Myeloid cell-restricted insulin receptor deficiency protects against obesity-induced inflammation and systemic insulin resistance. PLoS Genet, 6(5), e1000938.
  9. Gawlinski P, Nikolay R, Goursot C, Lawo S, Chaurasia B, Herz HM, Kussler-Schneider Y, Ruppert T, Mayer M, Grosshans J (2007). The Drosophila mitotic inhibitor Fruhstart specifically binds to the hydrophobic patch of cyclins. EMBO Rep, 8(5), 490-6.

Review

  1. Chaurasia B, Summers SA (2015). Ceramides - Lipotoxic Inducers of Metabolic Disorders. [Review]. Trends Endocrinol Metab, 26(10), 538-50.
  2. Siddique MM, Li Y, Chaurasia B, Kaddai VA, Summers SA (2015). Dihydroceramides: From Bit Players to Lead Actors. [Review]. J Biol Chem, 290(25), 15371-9.

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