Vijayalakshmi Nandakumar, PhD

Academic Information

  • Departments: Pathology - Assistant Professor (Clinical)
  • Divisions: Clinical Pathology

Academic Office Information

  • 800-522-2787
  • ARUP
    500 Chipeta Way
    Salt Lake City, UT 84108

Email: vijayalakshmi.nandakumar@path.utah.edu

Selected Publications

Journal Article

  1. Kottom TJ, Nandakumar V, Hebrink DM, Carmona EM, Limper AH (2020). A critical role for CARD9 in pneumocystis pneumonia host defence. Cell Microbiol, 22(10), e13235.
  2. Nandakumar V, Paul Theobald J, Algeciras-Schimnich A (2020). Evaluation of plasma ACTH stability using the Roche Elecsys immunoassay. Clin Biochem, 81, 59-62.
  3. Kottom TJ, Hebrink DM, Jenson PE, Nandakumar V, Wthrich M, Wang H, Klein B, Yamasaki S, Lepenies B, Limper AH (2017). The Interaction of Pneumocystis with the C-Type Lectin Receptor Mincle Exerts a Significant Role in Host Defense against Infection. J Immunol, 198(9), 3515-3525.
  4. Nandakumar V, Hebrink D, Jenson P, Kottom T, Limper AH (2017). Differential Macrophage Polarization from Pneumocystis in Immunocompetent and Immunosuppressed Hosts: Potential Adjunctive Therapy during Pneumonia. Infect Immun, 85(3).
  5. Huang XF, Nandakumar V, Tumurkhuu G, Wang T, Jiang X, Hong B, Jones L, Won H, Yoshii H, Ozato K, Masumi A, Chen SY (2016). Mysm1 is required for interferon regulatory factor expression in maintaining HSC quiescence and thymocyte development. Cell Death Dis, 7(6), e2260.
  6. Feng H, Wang X, Zhang Z, Tang C, Ye H, Jones L, Lou F, Zhang D, Jiang S, Sun H, Dong H, Zhang G, Liu Z, Dong Z, Guo B, Yan H, Yan C, Wang L, Su Z, Li Y, Nandakumar V, Huang XF, Chen SY, Liu D (2015). Identification of Genetic Mutations in Human Lung Cancer by Targeted Sequencing. Cancer Inform, 14, 83-93.
  7. Won H, Nandakumar V, Yates P, Sanchez S, Jones L, Huang XF, Chen SY (2014). Epigenetic control of dendritic cell development and fate determination of common myeloid progenitor by Mysm1. Blood, 124(17), 2647-56.
  8. Xu Z, Huo X, Tang C, Ye H, Nandakumar V, Lou F, Zhang D, Jiang S, Sun H, Dong H, Zhang G, Liu Z, Dong Z, Guo B, Yan H, Yan C, Wang L, Su Z, Li Y, Gu D, Zhang X, Wu X, Wei X, Hong L, Zhang Y, Yang J, Gong Y, Tang C, Jones L, Huang XF, Chen SY, Chen J (2014). Frequent KIT mutations in human gastrointestinal stromal tumors. Sci Rep, 4, 5907.
  9. Xu Z, Huo X, Ye H, Tang C, Nandakumar V, Lou F, Zhang D, Dong H, Sun H, Jiang S, Zhang G, Liu Z, Dong Z, Guo B, He Y, Yan C, Wang L, Su Z, Li Y, Gu D, Zhang X, Wu X, Wei X, Hong L, Zhang Y, Yang J, Gong Y, Tang C, Jones L, Huang XF, Chen SY, Chen J (2014). Genetic mutation analysis of human gastric adenocarcinomas using ion torrent sequencing platform. PLoS ONE, 9(7), e100442.
  10. Bai X, Zhang E, Ye H, Nandakumar V, Wang Z, Chen L, Tang C, Li J, Li H, Zhang W, Han W, Lou F, Zhang D, Sun H, Dong H, Zhang G, Liu Z, Dong Z, Guo B, Yan H, Yan C, Wang L, Su Z, Li Y, Jones L, Huang XF, Chen SY, Gao J (2014). PIK3CA and TP53 gene mutations in human breast cancer tumors frequently detected by ion torrent DNA sequencing. PLoS ONE, 9(6), e99306.
  11. Cai X, Sheng J, Tang C, Nandakumar V, Ye H, Ji H, Tang H, Qin Y, Guan H, Lou F, Zhang D, Sun H, Dong H, Zhang G, Liu Z, Dong Z, Guo B, Yan H, Yan C, Wang L, Su Z, Li Y, Jones L, Huang XF, Chen SY, Wu T, Lin H (2014). Frequent mutations in EGFR, KRAS and TP53 genes in human lung cancer tumors detected by ion torrent DNA sequencing. PLoS ONE, 9(4), e95228.
  12. Wang T, Nandakumar V, Jiang XX, Jones L, Yang AG, Huang XF, Chen SY (2013). The control of hematopoietic stem cell maintenance, self-renewal, and differentiation by Mysm1-mediated epigenetic regulation. Blood, 122(16), 2812-22.
  13. Nandakumar V, Chou Y, Zang L, Huang XF, Chen SY (2013). Epigenetic control of natural killer cell maturation by histone H2A deubiquitinase, MYSM1. Proc Natl Acad Sci U S A, 110(41), E3927-36.
  14. Jiang XX, Nguyen Q, Chou Y, Wang T, Nandakumar V, Yates P, Jones L, Wang L, Won H, Lee HR, Jung JU, Mschen M, Huang XF, Chen SY (2011). Control of B cell development by the histone H2A deubiquitinase MYSM1. Immunity, 35(6), 883-96.
  15. Nandakumar V, Vaid M, Katiyar SK (2011). (-)-Epigallocatechin-3-gallate reactivates silenced tumor suppressor genes, Cip1/p21 and p16INK4a, by reducing DNA methylation and increasing histones acetylation in human skin cancer cells. Carcinogenesis, 32(4), 537-44.
  16. Nandakumar V, Singh T, Katiyar SK (2008). Multi-targeted prevention and therapy of cancer by proanthocyanidins. Cancer Lett, 269(2), 378-87.