Education History
Fellowship |
University of California, San Francisco |
Postdoctoral Fellow |
---|---|---|
Washington University School of Medicine in St. Louis |
PhD | |
Fellowship |
Genomic Research Center, Academia Sinica |
Postbaccalaureate Research Fellow |
National Taiwan University School of Medicine |
BPharm | |
Undergraduate |
National Taiwan University School of Medicine |
BS |
Selected Publications
Journal Article
- Lo WL, Shah NH, Rubin SA, Zhang W, Horkova V, Fallahee IR, Stepanek O, Zon LI, Kuriyan J, Weiss A (2019). Slow phosphorylation of a tyrosine residue in LAT optimizes T cell ligand discrimination. Nat Immunol, 20(11), 1481-1493.
- Courtney AH, Shvets AA, Lu W, Griffante G, Mollenauer M, Horkova V, Lo WL, Yu S, Stepanek O, Chakraborty AK, Weiss A (2019). CD45 functions as a signaling gatekeeper in T cells. Sci Signal, 12(604).
- Lo WL, Shah NH, Ahsan N, Horkova V, Stepanek O, Salomon AR, Kuriyan J, Weiss A (2018). Lck promotes Zap70-dependent LAT phosphorylation by bridging Zap70 to LAT. Nat Immunol, 19(7), 733-741.
- Courtney AH, Lo WL, Weiss A (2017). TCR Signaling: Mechanisms of Initiation and Propagation. Trends Biochem Sci, 43(2), 108-123.
- Ransdell JL, Dranoff E, Lau B, Lo WL, Donermeyer DL, Allen PM, Nerbonne JM (2017). Loss of Navβ4-Mediated Regulation of Sodium Currents in Adult Purkinje Neurons Disrupts Firing and Impairs Motor Coordination and Balance. Cell Rep, 20(6), 1502.
- Persaud SP, Parker CR, Lo WL, Weber KS, Allen PM (2014). Intrinsic CD4+ T cell sensitivity and response to a pathogen are set and sustained by avidity for thymic and peripheral complexes of self peptide and MHC. Nat Immunol, 15(3), 266-74.
- Lo WL, Allen PM (2013). Self-peptides in TCR repertoire selection and peripheral T cell function. Curr Top Microbiol Immunol, 373, 49-67.
- Lo WL, Solomon BD, Donermeyer DL, Hsieh CS, Allen PM (2014). T cell immunodominance is dictated by the positively selecting self-peptide. Elife, 3, e01457.
- Lo WL, Allen PM (2012). Self-awareness: how self-peptide/MHC complexes are essential in the development of T cells. Mol Immunol, 55(2), 186-9.
- Lo WL, Donermeyer DL, Allen PM (2012). A voltage-gated sodium channel is essential for the positive selection of CD4(+) T cells. Nat Immunol, 13(9), 880-7.
- Huang CH, Chuang MH, Lo WL, Wu MS, Wu YH, Wu DC, Chiou SH (2011). Alkylhydroperoxide reductase of Helicobacter pylori as a biomarker for gastric patients with different pathological manifestations. Biochimie, 93(7), 1115-23.
- Morley SC, Wang C, Lo WL, Lio CW, Zinselmeyer BH, Miller MJ, Brown EJ, Allen PM (2010). The actin-bundling protein L-plastin dissociates CCR7 proximal signaling from CCR7-induced motility. J Immunol, 184(7), 3628-38.
- Lo WL, Felix NJ, Walters JJ, Rohrs H, Gross ML, Allen PM (2009). An endogenous peptide positively selects and augments the activation and survival of peripheral CD4+ T cells. Nat Immunol, 10(11), 1155-61.
- Lin YC, Kuo MW, Yu J, Kuo HH, Lin RJ, Lo WL, Yu AL (2008). c-Myb is an evolutionary conserved miR-150 target and miR-150/c-Myb interaction is important for embryonic development. Mol Biol Evol, 25(10), 2189-98.
- Lin YC, Hsieh LC, Kuo MW, Yu J, Kuo HH, Lo WL, Lin RJ, Yu AL, Li WH (2007). Human TRIM71 and its nematode homologue are targets of let-7 microRNA and its zebrafish orthologue is essential for development. Mol Biol Evol, 24(11), 2525-34.
- Chuang MH, Wu MS, Lo WL, Lin JT, Wong CH, Chiou SH (2006). The antioxidant protein alkylhydroperoxide reductase of Helicobacter pylori switches from a peroxide reductase to a molecular chaperone function. Proc Natl Acad Sci U S A, 103(8), 2552-7.
Conference Proceedings
- Ganti RS, Lo WL, McAffee DB, Groves JT, Weiss A, Chakraborty AK (2020). How the T cell signaling network processes information to discriminate between self and agonist ligands. Proceedings of the National Academy of Sciences of the United States of America.