Research

The majority of our research is focused on searching for and understanding genes that increase a person's risk of developing various diseases. Knowledge about inherited predisposition to these diseases will help lead to the ability of health care professionals to treat, and eventually prevent, these illnesses with greater success.

Studies

We study the role of genetics in disease progression through:

  • Familial Aggregation studies - Is there a genetic component to the disease, and what are the relative contributions of genes and the environment?
  • High-Risk Pedigree studies - Genotype and sequence data can tell us on which part of which chromosome the disease gene is located.
  • Association studies - Which allele of which gene is associated with the disease?

We conduct our research in several ways:

  • Examining large health databases to determine patterns and associations of various diseases
  • Enrolling participants to study families that have a high incidence of a particular disease and studying the genetic makeup of related affected individuals to identify the genes or variants responsible for the disorder in the pedigree.

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