Dr. Paul Bray Recipient of NIH Grant
Apr 20, 2018 9:00 AM
Congratulations to Dr. Paul Bray for his award of a NIH grant from the National Heart, Lung, and Blood Institute. The grant awarded from 2018 through 2022 is focused on in vivo studies of megakaryocyte microRNAs regulating platelet number and integrin activation. The goal of Dr. Bray’s studies is to glean insights into the molecular genetic mechanisms that contribute to blood platelet formation and function. Dr. Bray and his team will investigate the role of microRNA regulation of megakaryocyte gene expression and test the hypothesis that specific microRNAs modulate the development of megakaryocytes into platelets and platelet function. One additional aspect of their studies will be testing whether microRNAs can enhance the in vitro production of platelets as a potential therapeutic for thrombocytopenia and thrombocytosis.