Internal Medicine Department
Hematology Division

John D. Phillips, PhD

Email:    john.phillips@hsc.utah.edu

Education:

1983 – 1992    Ph.D. in Biochemistry, Darthmouth College, Hanover, New Hampshire

1979 – 1983    B.S. in Animal Science, University of New Hampshire, Durham, New Hampshire

Training:

1992 – 1995    Post-doctoral Fellow in Human Molecular Biology & Genetics, University of Utah, Salt Lake City, Utah

Research Interests:

Normal and defective heme biosynthesis

Recent Publications

  1. Ajioka RS, Phillips JD, Kushner JP. (2006). Biosynthesis of heme in mammals. Biochimica et Biophysica Acta, 1763(7), 723-36.
  2. Phillips JD, Kushner JP. (2005). Fast track to the porphyrias. Nat Med, 11(10), 1049-50.
  3. Phillips JD, Warby CA, Kushner JP. (2005). Identification of a novel mutation in the L-ferritin IRE leading to hereditary hyperferritinemia-cataract syndrome. Am J Med Genet A, 134(1), 77-9.
  4. Phillips JD, Whitby FG, Warby CA, Labbe P, Yang C, Pflugrath JW, Ferrara JD, Robinson H, Kushner JP, Hill CP. (2004). Crystal structure of the oxygen-dependant coproporphyrinogen oxidase (Hem13p) of Saccharomyces cerevisiae. J Biol Chem, 279(37), 38960-8.
  5. Phillips JD, Whitby FG, Kushner JP, Hill CP. (2003). Structural basis for tetrapyrrole coordination by uroporphyrinogen decarboxylase. EMBO J, 22(23), 6225-33.
  6. Schubert HL, Phillips JD, Hill CP. (2003). Structures along the catalytic pathway of PrmC/HemK, an N5-glutamine AdoMet-dependent methyltransferase. Biochemistry, 42(19), 5592-9.