School of Medicine

Neurology Headache Physiology Lab


Brennan K.C., Mendez JM, Theriot JJ, Sawant PM, Lopez-Valdes HE, Ju YS, Tang, YT. (2014) Minimum Conditions for the Induction of Cortical Spreading Depression in Brain Slices. J Neurophysiol. 2014 Aug 13.

Brennan, K.C., Bates, E.A., Shapiro, R.E., Zyuzin, J., Hallows, W.C., Huang, Y., Lee, H.Y., Jones, C.R., Fu, Y.H., Charles, A.C., and Ptacek, L.J. (2013) Casein kinase 1 delta mutations in familial migraine and advanced sleep phase. Sci Transl Med, 2013 May 1;5(183):183ra56. doi: 10.1126/scitranslmed.3005784.Cover, editorial..

Clarkson, A.N., Lopez-Valdes, H.E., Overman, J.J., Charles, A.C., Brennan, K.C.*, and Carmichael, S.T.* (2013) Multimodal examination of structural and functional remapping in the mouse photothrombotic stroke model. J Cereb Blood Flow Metab, doi:10.1038/jcbfm.2013.7. *Equal contribution.

Cortical Sensory Plasticity in a Model of Migraine with Aura. J. Neurosci., 32:15252-15261. Theriot JJ, Toga AW, Prakash N, Ju YS, Brennan KC.

Bogdanov, V.B., Bogdanova, O.V., Koulchitsky, S.V., Chauvel, V., Multon, S., Makarchuk, M.Y., Brennan, K.C., Renshaw, P.F., and Schoenen, J. (2013) Behavior in the open field predicts the number of KCl-induced cortical spreading depressions in rats. Behav Brain Res, Jan 1;236(1):90-3. doi: 10.1016/j.bbr.2012.08.004. Epub 2012 Aug 14. PMID: 22981717.

Brennan KC, Chang JC, He D, Huang H, Miura RM, Wilson PL, Wylie JJ. (2013) A Mathematical Model of the metabolic and perfusion effects on cortical spreading depression. PLoS One 2103 14;8(8).

Digre, K.B., and Brennan, K.C. (2012) Shedding light on photophobia. J Neuroophthalmol, Mar;32(1):68-81. doi: 10.1097/WNO.0b013e3182474548. Review. PMID: 22330853.

Ahn, A.H., and Brennan, K.C. (2012) Unanswered questions in headache: how does a migraine attack stop? Headache, Jan;52(1):186-187. doi: 10.1111/j.1526-4610.2011.02078.x. Epub 2012 Jan 3. PMID: 22221296.

Tang, Y.T., Kim, J., López-Valdés, H.E., Brennan, K.C., and Ju, Y.S. (2011) Development and characterization of a microfluidic chamber incorporating fluid ports with active suction for localized chemical stimulation of brain slices. Lab Chip, Jul 7;11(13):2247-2254. Epub 2011 May 12. PMID: 21562669.

Chang, J.C., Brennan, K.C., and Chou T. (2011) Tracking monotonically advancing boundaries in image sequences using graph cuts and recursive kernel shape priors. IEEE Trans Med Imaging, May;31(5):1008-1020. Epub 2011 Dec 5. PMID: 22156978 

Brennan, K.C. (2011) Turn down the lights! An irritable occipital cortex in migraine without aura. Neurology, 76(3):206-207.

Chang, J.C., Shook, L.L., Biag, J., Nguyen, E.N., Toga, A.W., Charles, A.C., and Brennan, K.C. (2010) Biphasic direct current shift, haemoglobin desaturation and neurovascular uncoupling in cortical spreading depression. Brain, 133(Pt 4):996-1012.

Lopez-Valdes, H.E., Beltran-Parrazal, L., Brennan, K.C., and Charles, A.C. (2010) Bradykinin increases resensitization of purinergic receptor signaling in glioma cells. Cancer Cell Int, 10:35.

Brennan, K.C., and Charles, A. (2010) An update on the blood vessel in migraine. Curr Opin Neurol, 23(3):266-274.

Tang, Y.T., Kim, J., Lopez-Valdes, H., Brennan, K.C., and Ju, Y.S. (2010) Microfluidic Chamber with Active Suction Ports for Localized Chemical Stimulation of Brain Slices. Proceedings of IEEE 23rd International Conference on Micro Electro Mechanical Systems. Hong Kong, China, 304-307.

Charles, A., and Brennan, K.C. (2010) The neurobiology of migraine. Handb Clin Neurol, 97:99-108.

Bates, E., Nikai, T., Brennan, K.C., Fu, Y.H., Charles, A., Basbaum, A., Ptacek, L., and Ahn, A. (2009) Sumatriptan alleviates nitroglycerin-induced mechanical and thermal allodynia in mice. Cephalalgia (Epub ahead of print).

Charles, A., and Brennan, K. (2009) Cortical spreading depression-new insights and persistent questions. Cephalalgia, 29(10):1115-1124.

Brennan, K.C., and Charles, A. (2009) Sleep and headache. Semin Neurol, 29(4):406-418.

Brennan, K.C., and Toga, A.W. (2009) Intraoperative optical imaging. In: Frostig R (Ed.), Methods for in vivo Optical Imaging of the Central Nervous System. CRC Press.

Charles, A., and Brennan, K.C. (2008) A touch of increased pain: cutaneous allodynia in migraine. Ann Neurol, 63(2):130-132.

Brennan, K.C., and Charles, A.C. (2008) Mechanisms of cortical spreading depression as targets for migraine therapy. In: OlesenJ, Ramadan N (Eds.), Frontiers in Headache Research: Innovative Drug Development for Headache Disorders. Oxford University Press.–––

Charles, A.C., and Brennan, K.C. (2008) Glial cell calcium signaling. In: Squire L (Ed.), Encyclopedia of Neuroscience. Elsevier Press.

Charles, A., Flippen, C., Romero Reyes, M., and Brennan, K.C. (2007) Memantine for prevention of migraine: a retrospective study of 60 cases. J Headache Pain, 8(4):248-250.

Brennan, K.C., Romero Reyes, M., Lopez Valdes, H.E., Arnold, A.P., and Charles, A.C. (2007) Reduced threshold for cortical spreading depression in female mice. Ann Neurol, 61(6):603-606.

Brennan KC, Charles A. (2007) Sumatriptan-naproxen combination for acute migraine. Nat Clin Pract Neurol 2007 Nov 11;3(11):604-5.

Brennan, K.C., Beltran-Parrazal, L., Lopez-Valdes, H.E., Theriot, J., Toga, A.W., and Charles, A.C. (2007) Distinct vascular conduction with cortical spreading depression. J Neurophysiol, 97(6):4143-4151.

Beltran-Parrazal, L., López-Valdés, H.E., Brennan, K.C., Díaz-Muñoz, M., de Vellis, J., and Charles, A.C. (2006) Mitochondrial transport in processes of cortical neurons is independent of intracellular calcium. Am J Physiol Cell Physiol, 291(6):C1193-1197.

Matsumoto, J., Saver, J.L., Brennan, K.C., and Ringman, J.M. (2005) Mitochondrial encephalomyopathy with lactic acidosis and stroke (MELAS). Reviews in Neurological Diseases, 2(1):30-34.

Brennan, K.C., Jurewicz, E.C., Ford, B., Pullman, S.L., and Louis, E.D. (2002) Is essential tremor predominantly a kinetic or a postural tremor? A clinical and electrophysiological study. Mov Disord, 17(2):313-316.

Sakai, N., Brennan, K., Weiss, L., and Matile, S. (1997) Toward Biomimetic Ion Channels Formed by Rigid-Rod Molecules: Length-Dependent Ion-Transport Activity of Oligo(p-Phenylene)s. J Am Chem Soc, 119: 8726-8727.