Selective attention and working memory play a profound role in many of the tasks of everyday life; from driving a car, to reading, to holding a conversation in a crowded room, these cognitive abilities are an integral part of all our goal-oriented interactions with the world around us. The ultimate goal of our research is an understanding of the neural basis of selective attention and working memory. In particular, we will study the role of prefrontal control of visual cortical signals in these cognitive processes. This work involves electrophysiological recording, electrical stimulation, and pharmacological manipulation of neural activity in awake, behaving animals trained to perform tasks involving covert attention, spatial, and object working memory.
- Bahmani Z, Daliri MR, Merrikhi Y, Clark CL, Noudoost B. Working Memory Enhances Cortical Representations via Spatially-specific Coordination of Spike Times. In press Neuron. 2018.
- Akbarian A, Niknam K, Parsa M, Clark K, Noudoost B, Nategh N. Developing a Nonstationary Computational Framework with Application to Modeling Dynamic Modulations in Neural Spiking Responses. IEEE Trans Biomed Eng. 2017 Oct 13.
- Merrikhi Y, Clark K, Albarran E, Parsa M, Zirnsak M, Moore T, Noudoost B. Spatial Working Memory Alters the Efficacy of Input to Visual Cortex. Nat Comm 2017; Apr 27; 8:15041. [Recommended by Faculty of 1000 Biology]
- Noudoost B, Nategh N, Clark KL, Esteky H. Stimulus context alters neural representations of faces in inferotemporal cortex. J Neurophys 2017; Jan 117(1):336-347.
- Clark KL, Squire RF, Merrikhi Y, Noudoost B. Visual attention: Linking prefrontal sources to neuronal and behavioral correlates. Prog Neurobiol 2015; Sep 132: 59-80.
- Hu M, Clark KL, Gong X, Noudoost B, Li M, Moore T, Liang H. Copula regression analysis of simultaneously recorded frontal eye field and inferotemporal spiking activity during object-based working memory. J Neurosci 2015; 35(23): 8745-57.
- Clark KL, Noudoost B. The role of prefrontal catecholamines in attention and working memory. Front Neural Circuits 2014; Apr 8: 8-33.
- Zirnsak M, Steinmetz NA, Noudoost B, Xu K, Moore T. Visual space is compressed in prefrontal cortex before eye movements. Nature 2014; 507: 504-7.
- Clark KL, Noudoost B, Moore T. Persistent spatial information in the frontal eye field during object-based short-term memory does not contribute to task J Cogn Neurosci 2014; 26(6): 1292-9.
- Noudoost B, Clark KL, Moore T. A distinct contribution of the frontal eye field to the visual representation of saccadic targets. J Neurosci 2014; 34:3678-98.
- Squire RF, Noudoost B, Schafer RJ, Moore T. Prefrontal contributions to visual selective attention. Ann Rev Neurosci 2013; 36:451-66.
- Soltani A, Noudoost B, Moore T. Dissociable dopaminergic control of saccadic target selection and its implications for reward modulation. Proc Natl Acad Sci 2013; 110: 3579-84.
- Noudoost B, Esteky H. Neuronal correlates of view representation revealed by face view aftereffect. J Neurosci 2013; 33: 5761-72.
- Noudoost B, Moore T. Parietal and prefrontal neurons driven to distraction. Nature Neurosci: News & Views 2013; 16(1): 8-9.
- Clark KL, Noudoost B, Moore T. Persistent spatial information in the frontal eye field during object-based short-term memory. J Neurosci 2012; 32(32):10907-14.
- Noudoost B, Moore T. The role of neuromodulators in selective visual attention. Trends Cogn Sci 2011; 15: 585-591.
- Noudoost B, Moore T. Control of visual cortical signals by prefrontal dopamine. Nature 2011; 474(7351): 372-375. [Recommended by Faculty of 1000 Biology]
- Noudoost B, Moore T. A reliable microinjectrode system for use in behaving monkeys. J Neurosci Methods 2011; 194(2): 218-223.
- Noudoost B, Chang MC, Steinmetz NA, Moore T. Top-down control of visual attention. Curr Opin Neurobiol 2010; 20(2): 183-190.
- Nilipour R, Saber GT, Noudoost B. Different profiles of verbal and nonverbal auditory impairment in cortical and subcortical lesions. Basic and Clinical Neuroscience 2010; 1(4): 14:24.
- Noudoost B, Afraz SR, Vaziri-Pashkam M, Esteky H. Visual spatial integrity in the absence of splenium. Brain Res 2006; 1076(1): 177-186.
- Noudoost B, Adibi M, Moeeny A, Esteky H. Configural and analytical processing of familiar and unfamiliar objects. Brain Res Cogn Brain Res 2005; 24(3): 436-441.
- Nilipour R, Clarke S, Noudoost B, Saber GT, Najlerahim A. Response time as an index for selective auditory cognitive deficits. Acta Neurobiol Exp 2004; 64(2): 163-170.