School of Medicine

Orthopaedics Research Labs

Research Support

Active:

NIH R21 AR069773-A1 4/1/2017 – 3/31/2019

In Vivo Arthrokinematics of Total Ankle Replacement and Ankle Arthrodesis
PI = Andrew Anderson, co-I: Alexej Barg, Charles Saltzman
Goals: The objective of this project is to quantify and compare in-vivo articulation of the primary ankle and adjacent joints during activities of daily living using dual-fluoroscopy. Motion will be displayed relative to the underlying anatomy to provide arthrokinematics of three groups: controls, post-TAR, and post-ankle arthrodesis.

NIH R01-AR067196 5/1/2016 – 4/30/2021

Biomechanics of reverse total shoulder arthroplasty
PI = Heath Henninger, Co-I: Andrew Anderson
Goals: Quantify the transient changes in scapulohumeral kinematics in reverse total shoulder patients during short term (<1 yr) recovery. Test the relationships between shoulder kinematics and implant hardware configuration in the laboratory using a dynamic shoulder simulator. Validate a predictive model of patient range of motion using both patient-specific and laboratory data.

PAC12 Research Grant 5/1/2018 – 4/30/2021

Developing a Comprehensive, Quantitative Understanding of Hip Morphometrics and Biomechanics in Collegiate Athletes at Risk for Developing Femoroacetabular Impingement Syndrome
PI = Andrew Anderson, co-I = Bo Foreman, Steve Aoki, Travis Maak
Goals: Determine if collegiate athletes are at a higher risk of developing femoroacetabular impingement syndrome based on the 3D shape of their hip. Develop predictive relationships between hip shape and kinematics, kinetics, and muscle activations measured in collegiate athletes.

Stryker/Orthopaedic Research Society Fellowship 4/1/2019 – 3/31/2019

Advancing Total Ankle Replacement Through Morphometric and Kinematic Analyses
PI = Amy Lenz; Sponsor = Andrew Anderson
Evaluate three-dimensional shape of the ankle joint complex using statistical shape modeling and quantify in-vivo joint motion of the prosthetic tibiotalar joint and adjacent subtalar joint. Data should inform the development of new prostheses that improves joint function and mobility.

LS-Peery Foundation 3/1/2018 – 2/28/2019

Qualitative and Quantitative Assessment of the Subtalar Joint Using Three-Dimensional Computed Tomography Models and High-Speed Dual-Fluoroscopy
PI = Alexej Barg, Nicola Krahenbuhl, Amy Lenz, co-I = Andrew Anderson
Goals: Determine how the appearance of the subtalar joint (in a neutral, weight-bearing position) changes as a function of the radiographic projection angle.  In addition, quantify the 3D anatomical variation and orientation of the posterior facet of the calcaneus in a cohort of asymptomatic adults without a history of ankle pathology. Finally, determine how the orientation of the subtalar joint in the coronal plane changes during activities of daily living.

Pending:

NIH 2R01EB016701-05 4/1/2019 – 3/31/2023

PI = Andrew Anderson, co-I = Jeff Weiss, Ross Whitaker, Shireen Elhabian, Chris Peters
Computational and Statistical Framework to Model Tissue Shape and Mechanics
Goals: Develop a framework to improve the efficiency in which computer models of tissue biomechanics and shape are developed and analyzed.

NIH R01 AR074416-01 9/1/2018 – 8/31/2023

PI = Andrew Anderson, co-I = Jeff Weiss, Neal Bangerter, Steve Aoki, Travis Maak, Chris Hanrahan, Chris Peters
Integrating Patient-Specific Computer Models with Quantitative Magnetic Resonance Imaging to Identify the Pathophysiology of Femoroacetabular Impingement Syndrome and Effects of Arthroscopic Surgery
Goals: Determine how surgery changes 3D hip shape, chondrolabral mechanics, and cartilage health.