In the Carey Lab, we study pathogenic mycobacteria, including the globally significant pathogen Mycobacterium tuberculosis. Our scientific goal is to understand how bacterial strain diversity impacts clinically relevant phenotypes, such as antibiotic resistance and vaccine escape.
- Hicks ND, Carey AF, Yang J, Zhao Y, Fortune SM. Bacterial Genome-Wide Association Identifies Novel Factors That Contribute to Ethionamide and Prothionamide Susceptibility in Mycobacterium tuberculosis. mBio. 2019 Apr 23;10(2):e00616-19. doi: 10.1128/mBio.00616-19. PMID: 31015328; PMCID: PMC6479004.
- Cadena AM, Hopkins FF, Maiello P, Carey AF, Wong EA, Martin CJ, Gideon HP, DiFazio RM, Andersen P, Lin PL, Fortune SM, Flynn JL. Concurrent infection with Mycobacterium tuberculosis confers robust protection against secondary infection in macaques. PLoS Pathog. 2018 Oct 12;14(10):e1007305. doi: 10.1371/journal.ppat.1007305. PMID: 30312351; PMCID: PMC6200282.