2021

Fogang B, Biabi, MF, Maloba, FM, Essangui E, Donkeu C, Cheteug G, Kapen M, Keumoe R, Nsango S, Eboumbou C, Megnekou R, Lamb TJ and Ayong, LS. High prevalence of asymptomatic malarial anemia and association with early clinical conversion in a P. falciparum hyper-endemic setting in Cameroon. AJTMH, in press

Olatunde AC, Hale JS, Lamb TJ. Cytokine-skewed Tfh cells: functional consequences for B cell help. Trends Immunol. 2021 Jun;42(6):536-550. PMID: 33972167

Pham TT, Lamb TJ, Deroost K, Opdenakker G, Van den Steen PE. Hemozoin in Malarial Complications: More Questions Than Answers. Trends Parasitol. 2021 Mar;37(3):226-239. PMID: 33223096 

2020

Srey MT, Taccogna A, Oksov Y, Lustigman S, Tai PY, Acord J, Selkirk ME, Lamb TJ, Guiliano DB. Vaccination with novel low-molecular weight proteins secreted from Trichinella spiralis inhibits establishment of infection. PLoS Negl Trop Dis. 2020 Nov 18;14(11):e0008842. PMID: 33206649

Kolawole EM, Lamb TJ, Evavold BD. Relationship of 2D Affinity to T Cell Functional Outcomes. Int J Mol Sci. 2020 Oct 27;21(21):7969. PMID: 33120989

Darling TK, Schenk MP, Zhou CC, Maloba FM, Mimche PN, Gibbins JM, Jobe SM, Lamb TJ. Platelet α-granules contribute to organ-specific pathologies in a mouse model of severe malaria. Blood Adv. 2020 Jan 14;4(1):1-8. PMID: 31891656

Darling TK, Mimche PN, Bray C, Umaru B, Brady LM, Stone C, Eboumbou Moukoko CE, Lane TE, Ayong LS, Lamb TJ. EphA2 contributes to disruption of the blood-brain barrier in cerebral malaria. PLoS Pathog. 2020 Jan 30;16(1): e1008261. PMID: 31999807 

2019

Joyner CJ, Brito CFA, Saney CL, Joice Cordy R, Smith ML, Lapp SA, Cabrera-Mora M, Kyu S, Lackman N, Nural MV, DeBarry JD MaHPIC Consortium, Kissinger JC, Styczynski MP, Lee FE*, Lamb TJ*, Galinski MR*. (2019) Humoral immunity prevents clinical malaria during Plasmodium relapses without eliminating gametocytes. PLoS Pathog. 15(9):e1007974. PMID: 31536608
* Co-corresponding authors

Darling TK, Lamb TJ. (2019) Emerging Roles for Eph Receptors and Ephrin Ligands in Immunity. Front Immunol. 2019 10:1473 PMID: 31333644

Mimche SM, Lee CM, Liu KH, Mimche PN, Harvey RD, Murphy TJ, Nyagode BA, Jones DP, Lamb TJ, Morgan ET (2019) A non-lethal malarial infection results in reduced drug metabolizing enzyme expression and drug clearance in mice. Malar J. 18(1):234 PMID: 31299982

Tunon-Ortiz A, Lamb TJ. (2019) Blood brain barrier disruption in cerebral malaria: Beyond endothelial cell activation. PLoS Pathog. 2019 15(6):e1007786. PMID: 31247027

2018

Qiu Y, Ahn B, Sakurai Y, Hansen CE, Tran R, Mimche PN, Mannino RG, Ciciliano JC, Lamb TJ, Joiner CH, Ofori-Acquah SF, Lam WA. (2018) Microvasculature-on-a-chip for the long-term study of endothelial barrier dysfunction and microvascular obstruction in disease. Nat Biomed Eng. 2:453-463. PMID:30533277

Morgan ET, Dempsey JL, Mimche SM, Lamb TJ, Kulkarni S, Cui JY, Jeong H, Slitt AL.(2018)
Physiological Regulation of Drug Metabolism and Transport: Pregnancy, Microbiome, Inflammation, Infection, and Fasting. Drug Metab Dispos.46(5):503-513. PMID: 29514828

2017

Tang Y, Joyner CJ, Cabrera-Mora M, Saney CL, Lapp SA, Nural MV, Pakala SB, DeBarry JD, Soderberg S; MaHPIC Consortium, Kissinger JC, Lamb TJ, Galinski MR, Styczynski MP. (2017) Correction to: Integrative analysis associates monocytes with insufficient erythropoiesis during acute Plasmodium cynomolgi malaria in rhesus macaques. Malar J. 16(1):486. PMID: 29202752

Tang Y, Joyner CJ, Cabrera-Mora M, Saney CL, Lapp SA, Nural MV, Pakala SB, DeBarry JD, Soderberg S; MaHPIC Consortium, Kissinger JC, Lamb TJ, Galinski MR, Styczynski MP. (2017) Integrative analysis associates monocytes with insufficient erythropoiesis during acute Plasmodium cynomolgi malaria in rhesus macaques. Malar J.16(1):384. Erratum in: Malar J. 2017 Dec 4;16(1):486. PMID: 28938907

Lin, J, Sondekamp, J, Cunningham, D, Deroost, K, Tshitenge,T, McLaughlin, S, Lamb, T, Spencer-Dean, B, Hosking, C, Ramesar, J, Janse, C, Graham, C, O’Garra, A and Langhorne, J. (2017) Signatures of malaria-associated pathology revealed by high-resolution whole-blood transcriptomics in a rodent model of malaria. Scientific Reports, 7: 41722 PMID: 28155887

2016

Joyner C, Moreno A, Meyer EV, Cabrera-Mora M; MaHPIC Consortium, Kissinger JC, Barnwell JW, Galinski MR. (2016). Plasmodium cynomolgi infections in rhesus macaques display clinical and parasitological features pertinent to modelling vivax malaria pathology and relapse infections. Malaria Journal 15(1):451  PMID: 27590312

Hudson, LE, McDermott, CD, Stewart, TP, Hudson, WH, Fasken, MB, Corbett, AH and Lamb, TJ. (2016). Characterization of the Probiotic Yeast Saccharomyces boulardii in the Healthy Mucosal Immune System. PLoS One 11(4) e0153351 PMID: 27064465

Hudson, LE, Stewart, TP, Fasken, M, Corbett, AH and Lamb, TJ. (2016) Transformation of Probiotic Yeast and their Recovery from Gastrointestinal Immune Tissues Following Oral Gavage in Mice. J Vis Exp 108 PMID: 26890281

2015

Mimche, PN, Brady, LM, Bray, CF, Hudson, LE, Fenne DW, Keeton, S, Lamb, TJ. (2015). Expression of the receptor tyrosine kinase EphB2 on dendritic cells is modulated by Toll-like receptor ligation but is not required for T cell activation. PLoS One 10(9): e0138835   PMID: 26407069

Matar CM, Anthony N, Jacobs N, Priyamvada L, Engwerda C, Speck, SH* and Lamb TJ*(2015). Gammaherpes virus co-infection impairs the generation of anti-malaria immunity turning a non-lethal malaria infection into a lethal one. PLOS pathogens 11(5):e1004858 PMID:25996913 *co-corresponding authors

Mimche, PN, Brady, LM, Bray, CF, Thapa, M, McDermott, CD, King, TP, Quicke, K, Lee, CM, Mimche, SM, Grakoui, A, Morgan, ET and Lamb TJ (2015) The receptor tyrosine kinase EphB2 contributes to liver fibrosis during mouse malaria infection. Hepatology 62(3): pp900-14 PMID: 25784101

2014

Hudson, LE, Fasken, MB, McDermott, CD, Kuiper, EG, Guiliano, DB, Corbett, AH and Lamb, TJ (2014). Functional heterologous protein expression by genetically engineered probiotic yeast Saccharomyces boulardii. PLOS One 9 (11): e112660 PMID: 25391025

2013

Abanyie FA, McCracken C, Kirwan P, Molloy SF, Asaolu SO, Holland CV, Gutman J and Lamb TJ (2013). Ascaris co-infection does not alter malaria-induced anaemia in a cohort of Nigerian preschool children. Malaria Journal12(1): e1. PMID: 23282136

2012

Freitas do Rosario, AP, Lamb, TJ, Spence, P, Stephens, R, Lang, A, Roers, A, Muller, W, O’Garra, A and Langhorne, J (2012). IL-27 promotes IL-10 production by effector Th1 CD4+ T cells; a critical mechanism for protection from severe immunopathology during malaria infection. Journal of Immunology, 188 (3), pp1178-90 PMID: 22205023

2011

Fairlie-Clarke, KJ, Lamb, TJ, Langhorne, J, Graham, AL and Allen, JE (2010). Antibody isotype analysis of malaria-nematode co-infection: problems and solutions associated with cross-reactivity. BMC Immunology 11, p6 PMID: 20163714

2010

Saunders, A, Lamb, TJ, Pascall, J, Hutchings, A, Dion, C, Carter, C, Hepburn, L, Miller, JR, Langhorne, J and Butcher, GW (2009). No impact of malaria infection or immunisation on the expression of the immune GTPase GIMAP1 at the protein or mRNA levels. Malaria Journal, 8, p53. PMID: 19338674

2009

Cadman, ET, Sponaas, AM, Voisine, CV, Lamb, TJ, Ndung’u, F, Jarra, W, Harrison, V and Langhorne, J  (2008). Alterations of splenic microarchitecture in malaria are induced independently of Toll-like receptors 2, 4, 9 or MyD88, and may affect antibody affinity. Infection and Immunity, 76 (9), pp3924-3931. PMID: 18559428

Lamb, TJ and Langhorne, J. (2008) The severity of anaemia in Plasmodium chabaudi infections of BALB/c mice is determined independently from the number of circulating parasites. Malaria Journal, 7 p68 PMID: 18439291

Fenton, A, Lamb, TJ and Graham, AL (2008). Optimality analysis of Th1 /Th2 immune responses during microparasite co-infection. Parasitology 28 pp1-13. PMID: 18442426

Lamb, TJ, Harris, A, Le Goff, L, Read, AF and Allen, JE. (2008). Litomosoides sigmodontis: vaccine-induced immune responses against Wolbachia surface protein can enhance the survival of filarial nematodes during primary infection. Experimental Parasitology 118(2) pp285-289 PMID: 17919582

2007

Lamb, TJ, Voisine, C, Koernig, S, Egan, CA, Harnett, W and Langhorne, J. (2007) The pathology of Plasmodium chabaudi infection is not ameliorated by the secreted filarial nematode immunomodulatory molecule, ES-62. Parasite Immunology 29 pp271-276.  PMID:17430551

2005

Lamb, TJ, Graham, AL, Le Goff, L and Allen, JE (2005). Co-infected C57BL/6 mice mount appropriately polarized and compartmentalized cytokine responses to Litomosoides sigmodontis and Leishmania major but disease progression is altered. Parasite Immunology 27(9) pp317-324. PMID: 16149989

Graham, AL, Taylor, MD, Le Goff, L, Lamb, TJ and Allen, JE (2005). Quantitative appraisal of murine filariasis confirms host strain differences but reveals that BALB/c females are more susceptible than males to Litomosoides sigmodontis. Microbes and Infection 7(4) pp612-618. PMID: 15820154

Graham, AL, Lamb, TJ, L, Read, AF and Allen, JE (2005). Malaria-filaria co-infection in mice makes malarial disease more severe unless filarial infection achieves patency. Journal of Infectious Diseases 191(3) pp410-421 PMID:15633101

2004

*Lamb, TJ, Le Goff, L, Kurniawan, A, Read, AF, Guiliano, DB, Fenn, K, Blaxter, M and Allen, JE (2004). The larval stage contributes to the majority of the response against Wolbachia surface protein in filarial nematode infection. Journal of Infectious Diseases 189(1) pp120-127 PMID: 14702162  *Paper recommended to the Faculty of 1000

2002

Le Goff, L, Lamb TJ, Graham, AL, Harcus, Y and Allen, JE. (2002). IL4 is required to prevent filarial nematode development in resistant but not susceptible strains of mice. International Journal for Parasitology 32(10) pp1277-1282 PMID: 12204227

2001

Djikeng A, Ferreira L, D'Angelo M, Dolezal P, Lamb T, Murta S, Triggs V, Ulbert S, Villarino A, Renzi S, Ullu E, Tschudi C (2001) Characterisation of a candidate Trypanosoma brucei U1 snRNA gene. Molecular and Biochemical Parasitology113 (1) pp109-115. PMID: 11254959