Clinical Trials Office Publications

2013

1. Zobell JT, Young DC, Waters D, Stockmann C, Ampofo K, Sherwin CM, Spigarelli, MG.
   Optimization of antipseudomonal Antibiotics for Cystic Fibrosis Pulmonary Exacerbations: II. Cephalosporins and Pencillins.
   Pediatri Pulmonol. 2013 Feb;48(2):107-22. doi:10.1002/ppul.22669.
2. Stockmann C, Sherwin CM, Zobell JT, Young DC, Waters D, Spigarelli, MG, Ampofo K.
   Optimization of antipseudomonal Antibiotics for Cystic Fibrosis Pulmonary Exacerbations: III. Fluoroquinolones.
   Pediatr Pulmonol. 2013 Sep 4. doi: 10.1002/ppul.22667. [Epub ahead of print]
3. Young DC, Zobell JT, Waters CD, Ampofo K, Stockmann C, Sherwin CM, Spigarelli MG.
   Optimization of antipseudomonal antibiotics for cystic fibrosis pulmonary exacerbations: IV. colistimethate sodium.
   Pediatr Pulmonol. 2013 Jan;48(1):1-7. doi: 10.1002/ppul.22664.
4. Campbell, S, Spigarelli, MG, Coulter, J., Sherwin, CM.
   Metabolic and Toxicological Considerations for Sepsis Drug Treatments.
   Expert Opin Drug Metab Toxicol. 2013 Jan;9(1):79-89. doi: 10.1517/17425255.2012.727396.
5. Zobell JT, Young DC, Waters CD, Ampofo K, Stockmann C, Sherwin CM, Spigarelli MG.
   Optimization of antipseudomonal antibiotics for cystic fibrosis pulmonary exacerbations: VI. Executive summary.
   Pediatr Pulmonol. 2013 Jan 28. doi: 10.1002/ppul.22757. [Epub ahead of print]
6. David C Young. Jeffery T Zobell, Dustin Waters, Krow Ampofo, Chris Stockmann, Catherine Sherwin, Michael Spigarelli.
   Optimization of antipseudomonal Antibiotics for Cystic Fibrosis Pulmonary Exacerbations: V. Aminolgycoside.
   Pediatr Pulmonol. 2013 [in press]
7. Kimberlin DW, Acosta EP, Prichard MN, Sánchez PJ, Ampofo K, Lang D, Ashouri N, Vanchiere JA, Abzug MJ, Abughali N, Caserta MT, Englund JA, Sood SK, Spigarelli MG, Bradley JS, Lew J, Michaels MG, Wan W, Cloud G, Jester P, Lakeman FD, Whitley RJ; for the National Institute of Allergy and Infectious Diseases Collaborative Antiviral Study Group.
   Oseltamivir Pharmacokinetics, Dosing, and Resistance Among Children Aged <2 Years With Influenza.
   J Infect Dis. 2013 Jan 10. [Epub ahead of print]

2012

1. Sherwin CMT, Sagcal-Gironella AC, Fukuda, T, Brunner, HI, and Vinks, AA.
   Development of a population pharmacokinetic model with enterohepatic circulation of mycophenolic acid in patients with childhood-onset systemic lupus erythematosus (cSLE).
   Br J Clin Pharmacol. 2012 May;73(5):727-40 doi: 10.1111/j.1365-2125.2011.04140.x.
2. De Cock, RFW, Allegaert, K., Schreuder, MF., Sherwin, CM., de Hoog, M., Danhof, M and Knibbe, CAJ.
   Maturation of glomerular filtration rate in neonates as reflected by amikacin clearance.
   Clin Pharmacokinet. 2012 Feb 1;51(2):105-17doi: 10.2165/11595640-000000000-00000.
3. Kiang, TKL, Sherwin CM, Spigarelli, MG, and Ensom, MHH.
   Fundamentals of Population Pharmacokinetic: Modeling and Software.
   Clin Pharmacokinet. 2012 Aug 1;51(8):515-25. doi: 10.2165/11634080-000000000-00000.
4. Sherwin CM, Kiang, TKL, Spigarelli, MG, and Ensom, MHH.
   Fundamentals of Population Pharmacokinetic Modeling: Validation methods.
   Clin Pharmacokinet. 2012 Jul 16. doi: 10.2165/11634200-000000000-00000.
5. Hanson KE, Pfeiffer CD, Lease ED, Balch AH, Zaas AK, Perfect JR, Alexander BD.
   β-D-glucan surveillance with preemptive anidulafungin for invasive candidiasis in intensive care unit patients: a randomized pilot study.
   PLoS One. 2012;7(8):e42282. doi: 10.1371/journal.pone.0042282.
6. Thompson SD, Marion MC, Sudman M, Ryan M, Tsoras M, Howard TD, Barnes MG, Ramos PS, Thomson W, Hinks A, Haas JP, Prahalad S, Bohnsack JF, Wise CA, Punaro M, Rosé CD, Pajewski NM, Spigarelli M, Keddache M, Wagner M, Langefeld CD, Glass DN.
   Genome-wide association analysis of juvenile idiopathic arthritis identifies a new susceptibility locus at chromosomal region 3q13.
   Arthritis Rheum. 2012 Aug;64(8):2781-91. doi: 10.1002/art.34429.
7. Zobell JT, Waters D, Young DC, Stockmann C, Ampofo K, Sherwin CM, Spigarelli, MG.
   Optimization of antipseudomonal Antibiotics for Cystic Fibrosis Pulmonary Exacerbations: I. Aztreonam and Carbapenems.
   Pediatr Pulmonol. 2012 Dec;47(12):1147-58. doi: 10.1002/ppul.22655.
8. Sherwin, CMT, Saldana SN, Bies, R, Anam, M and Vinks, AA.
   Population PK modeling of risperidone and 9-OH risperidone to estimate two subpopulations in adolescents.
   Ther Drug Monit. 2012 Oct;34(5):535-544.

2011

1. Sherwin, CM, Fukuda, T, Brunner, HI, Goebel, J, and Vinks, AA.
   The Evolution of Population Pharmacokinetic Models to Describe the Enterohepatic Recycling of Mycophenolic Acid in Solid Organ Transplantation and Autoimmun Disease (review) Clin Pharmacokinet. 2011;50(1):1-24. doi:10.2165/11536640-000000000-00000.
2. Sagcal-Gironella AC, Fukuda, T, Wiers, K, Cox, S, Nelson, S, Dina, B, Sherwin, CM, Klein-Gitelman, M, Vinks, AA and Brunner, HI.
   Pharmacokinetics and Pharmacodynamics of Mycophenolic Acid and their Relation to Response to Therapy of Childhood-onset Systemic Lupus Erythmatosus.
   Semin Arthritis Rheum. 2011; 40(4):307-13. doi:10.1016/j.semarthrit.2010.05.007.
3. Gerlach LS, Saldaña SN, Wang Y, Nick TG, Spigarelli MG.
   Retrospective review of the relationship between weight change and demographic factors following initial depot medroxyprogesterone acetate injection in adolescents.
   Clin Ther. 2011 Feb;33(2):182-7. doi: 10.1016/j.clinthera.2011.02.008.
4. Merhar SL, Schibler KR, Sherwin CM, Meinzen Derr J, Shi J, Balmakund T, and Vinks AA.
   Pharmacokinetics of Levetiracetam in Neonates with Seizures.
   J Pediatr. 2011 ;159(1):152-154.e3  doi:10.1016/j.jpeds.2011.03.057.
5. Sherwin CM, Ding, L, Kaplan, J, Spigarelli, M and Vinks, AA.
   Optimal study design for pioglitazone in septic pediatric patients.
   J Pharmacokinet Pharmacodyn. 2011 ;38(4):433-47. doi: 10.1007/s10928-011-9202-8.
6. Sagcal-Gironella AC, Sherwin CM, Tirona, RG, Rieder MJ, Brunner, HI, Vinks AA.
   Pharmacokinetics of Prednisolone at Steady State in Young Patients With Systemic Lupus Erythematosus on Prednisone Therapy: An Open-Label, Single-Dose Study.
   Clin Ther. 2011 Oct;33(10):1524-36. doi:10.1016/j.clinthera.2011.09.015.
7. Zobell JT, Stockmann C, Young DC, Cash J, McDowell BJ, Korgenski K, Sherwin CM, Spigarelli M, Chatfield BA, Ampofo K.
   Population pharmacokinetic and pharmacodynamic modeling of high dose intermittent ticarcillin-clavulanate administration in pediatric cystic fibrosis patients.
   Clin Ther. 2011 Nov;33(11):1844-50. Epub 2011 Oct 21 doi:10.1016/j.clinthera.2011.09.010.

Book Chapters

• Children's Environmental Health, Chapter # 47, Obesity, Diabetes, and Cardiovascular Disease, NL Mihalopoulos
• Clinical Obstetrics and Gynecology, Pharmacology and Pharmacogenomics of neurological medications in pregnancy, Campbell, S, Spigarelli, MG June 2013 issue