Publications

Hu X, Zhang YQ, Lee OW, Liu L, Tang M, Lai K, Boxer MB, Hall MD, Shen M. Discovery of novel inhibitors of human galactokinase by virtual screening. J Comput Aided Mol Des. 2019 Apr;33(4):405-417. doi: 10.1007/s10822-019-00190-3. Epub 2019 Feb 26.

Siddiqi A, Webb F, Smotherman C, Shuja S, Mubeen A, Lai K. Prevalence of epithelial abnormalities and high-risk human papilloma virus in cervicovaginal Pap smears of population subgroups as a guide toward evidence-based best practice. Diagn Cytopathol. 2019 Jul;47(7):648-652. doi: 10.1002/dc.24158. Epub 2019 Feb 23. PubMed PMID: 30801970.

Balakrishnan B, Verheijen J, Lupo A, Raymond K, Turgeon C, Yang Y, Carter KL, Whitehead KJ, Kozicz T, Morava E, Lai K. A novel phosphoglucomutase-deficient mouse model reveals aberrant glycosylation and early embryonic lethality. J Inherit Metab Dis. 2019 May 11;. doi: 10.1002/jimd.12110. [Epub ahead of print] PubMed PMID: 31077402.

Balakrishnan B, Siddiqi A, Mella J, Lupo A, Li E, Hollien J, Johnson J, Lai K. Salubrinal enhances eIF2α phosphorylation and improves fertility in a mouse model of Classic Galactosemia Biochim Biophys Acta Mol Basis Dis. 2019 Nov 1;1865(11):165516. doi: 10.1016/j.bbadis.2019.07.010. Epub 2019 Jul 27.

Balakrishnan B, An D, Nguyen V, DeAntonis C, Martini PGV, Lai K. Novel mRNA-based therapy reduces toxic galactose metabolites and overcomes galactose sensitivity in a mouse model of Classic Galactosemia (in press, Molecular Therapy (Cell Press) https://doi.org/10.1016/j.ymthe.2019.09.018

Welsink-Karssies M, van Weeghel M, Elfrink H, Hollak C, Janssen M, Lai K, Langendonk J, Oussoren E, Ruiter J, Treacy E, de Vries M, Ferdinandusse S, Bosch A (2020) The Galactose Index measured in fibroblasts of GALT deficient patients distinguishes variant patients detected by newborn screening from patients with classical phenotypes (in press, Molecular Genetics and Metabolism)

Yang Y, Vankayalapati H, Tang M, Zheng Y, Li Y, Ma C, Lai K (2020) Discovery of novel inhibitors targeting multi-UDP-hexose pyrophosphorylases as anticancer agents. (in press, Molecules)

Contact Us

Kent Lai
Phone: 801-581-4510
Email: kent.lai@hsc.utah.edu

Division of Medical Genetics,
Department of Pediatrics
University of Utah School of Medicine,
295 Chipeta Way, Salt Lake City, UT 84108, U.S.A.