Neural and antidepressant effects of propofol
We are investigating the neural and clinical actions of propofol, a general anesthetic agent that may have antidepressant effects.
Endogenous opioid modulation by ketamine
This study is testing the hypothesis that the rapid antidepressant effects of ketamine are mediated by the endogenous opioid system.
Manipulation of mood circuits with precision TMS
Cutting-edge transcranial magnetic stimulation (TMS) tools are being applied to probe the neural circuits that are disrupted in mood disorders.
Neuropeptide Y and reward circuitry
We are examining individual differences in neural function caused by naturally occurring variation in NPY, a peptide neurotransmitter implicated in multiple neuropsychiatric disorders.
Predictors of response to ECT
This study aims to combine clinical and biological markers to identify subtypes of depression that respond best to electroconvulsive therapy (ECT).