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Research Highlights - Spring 2021


WELCOME OUR NEW CLINICAL RESEARCH MANAGER

Margaret Carlson, MPH CPH

margaret carlsonMs. Carlson received her undergraduate degree in Sociology with a minor in Pediatric Research and completed a Master of Public Health program in 2019. She went on to start a Doctorate in Public Health, emphasizing on patient provider communications, at the University of Utah and is pursuing this alongside her professional development. Previously, Ms. Carlson worked as the study coordinator for the Division of Emergency Medicine overseeing 3-4 advanced research associates where she was also the program director for the Research Associate Program conducted in the Emergency Division at the University Hospital.

Margaret is passionate about learning and looks forward to growing clinical research within CT Surgery.

WHAT’S HAPPENING

The Dosdall lab, together with an interdisciplinary team including Doug Smego MD from CT surgery, Robin Shaw MD PhD from Cardiovascular Medicine, and Ting Ting Hong PhD from Pharmacology, is developing a large animal ischemic heart failure model for testing novel therapeutic treatment options for patients with heart failure. This model will play an important role in research efforts at the CVRTI in the future. Initial results with a novel cBIN1 gene therapy have been very promising.

RECENT PUBLICATIONS

33+ publications since the start of the new year!

Wohlfahrt P, Nativi-Nicolau J, Zhang M, Selzman CH, Greene T, Conte J, Biber JE, Hess R, Mondesir FL, Wever-Pinzon O, Drakos SG, Gilbert EM, Kemeyou L, LaSalle B, Steinberg BA, Shah RU, Fang J, Spertus JA, Stehlik J. Quality of Life in Patients with Heart Failure With Recovered Ejection Fraction. JAMA Cardiol. 2021 May 5. Doi: 10.1001/jamacardio.2021.0939. PMID: 33950162. Link.

Beesley SJ, Sorenen J, Walkey AJ, Tonna JE, Lanspa MJ, Hirshberg E, Grissom CK, Horne BD, Burk R, Abraham TP, Paine R, Brown SM. Long-Term Implications of Abnormal Left Ventricular Strain During Sepsis. Crit Care med. 2021 Apr 1; 49(4): e444-e453. Doi: 10.1097/CCM. 0000000000004886. PMID: 33591007. Link.

Metcalf RA, Goodfellow J, Cali K, Blaylock R, Kawamoto K, Enniss T, Galaviz C, Ming L, Reddy S, Sharma V, Wanner N. Electronic clinical decision support: Evidence that default settings influence end-user behavior. Transfusion. 2021 Mar; 61(3): 669-670. Doi: 10.111/trf.16269. PMID: 33438332. Link.

Selzman CH, Tonna JE, Pierce J, Vargas C, Skidmore C, Lewis G, Hatton ND, Phillips JD. A pilot trial of human amniotic fluid for the treatment of COVID-19. BMC Res Notes. 2021 Jan 22;14(1):32.

Check out more of our research publications.

UPCOMING STUDIES

PI: Craig Selzman, MD

Project: A Phase 2 Proof of Concept, Double-Blind, Randomized, Placebo-controlled Study to Evaluate the Efficacy of ASP1128 (MA-0217) in Subjects at Risk for Acute Kidney Injury Following Coronary Artery Bypass Graft (CABG) and/or Valve Surgery

Sponsor: Astellas Pharma Inc

Enrollment Start: May 2021

DID YOU KNOW?

CT Surgery Research encompasses:

  • Adult Cardio
  • Pediatric Cardio (Primary Children’s)
  • Huntsman team (Huntsman Cancer Institute)
  • Animal Lab Research
  • Perfusion

Don’t see your publication or research highlight? Want to share new updates or projects in the works? Please contact Margaret (Margaret.carlson@hsc.utah.edu) to reflect in the next newsletter.