Diana I. Brixner, PhD, RPh

Languages

  • English
  • German

Academic Information

  • Departments: Pharmacotherapy - Professor, Population Health Sciences - Adjunct Professor
  • Divisions: Health System Innovation and Research
  • Cancer Center Programs: Affiliate, non-programmatically aligned

Academic Office Information

  • 801-581-3182
  • L.S. Skaggs Pharmacy Institute
    Pharmacy Practice
    30 S 2000 E
    Salt Lake City, UT 84112

Academic Bio

Dr. Brixner serves as Professor and Chair of the Department of the Pharmacotherapy and as Executive Director of the Pharmacotherapy Outcomes Research Center (PORC) in the College of Pharmacy at the University of Utah. More specifically, through her additional appointment as the Director of Outcomes for the University of Utah Program in Personalized Health Care, she is applying these skills towards evaluation of personalized, or targeted, technologies in oncology. Her research interests are focused in general on demonstrating the value to providers, patients, payers and to society of new technologies in the delivery of health care. Her sabbatical at UMIT University of Health Sciences, Medical Informatics and Technology and the Oncotyrol Center for Personalized Cancer Medicine (www.umit.at; http://www.oncotyrol.at) in Austria has expanded her scope of expertise in applying decision analytical modeling to assist in these evaluations with international collaborators. Dr. Brixner’s most recent research interests have focused on the application of personalized medicine in oncology for women with breast cancer. Her efforts are particularly timely as expensive medications have come to the market to this disease in targeted populations and patients need to weigh the side effects of these drugs against their own preferences for treatment pathways. Patients need more information on the benefit and potential harm of thee new technologies in making more informed decisions on targeted treatment pathway options.

Education History

Type School Degree
Certification University of Health Sciences, Medical Informatics and Technology (UMIT)
Epidemiology
Certificate
Certification University of Health Sciences, Medical Informatics and Technology
Health Sciences, Hall in Tirol, Austria
Certificate
Doctoral Training University of Utah
Medicinal Chemistry
Ph.D.
Undergraduate University of Rhode Island
Pharmacy
B.S.

Global Impact

Education History

Type School Degree Country
Certification University of Health Sciences, Medical Informatics and Technology (UMIT)
Epidemiology
Certificate Austria
Certification University of Health Sciences, Medical Informatics and Technology
Health Sciences, Hall in Tirol, Austria
Certificate Austria

Career

Institution Description Country
Oncotyrol GmbH in Health Technology Assessment Associated Researcher Austria

Selected Publications

Journal Article

  1. Saverno K, Neu, G, Schmidt S, Wolf D, Conrads-Frank A, Jahn B, Sroczynski G, Brixner, DI (10/28/2013). Medical Decision Analysis for the First-line Therapy of Chronic Myeloid Leukemia. Leuk Lymphoma.
  2. Ghate SR, Porucznik CA, Said Q, Hashibe M, Joy E, Brixner DI (March 1, 2013). Association Between Second-generation Antipsychotics and Changes in Body Mass Index in Adolescents. J Adolesc Health, 52(3), 336-43.
  3. Documentation of chemotherapy infusion preparation costs in academic- and community-based oncology practices.Brixner DI, Oderda GM, Nickman NA, Beveridge R, Jorgenson JA (2006). Documentation of chemotherapy infusion preparation costs in academic- and community-based oncology practices. Journal of the National Comprehensive Cancer Network, 4(3), 197-208.
  4. Brixner DI, Oderda GM, Nickman NA, Servatius D, Lambert A, Bancroft F, Bretzel R, Beveridge R, Vermulen L, Lentz S (2005). Documentation of pharmacy cost in the preparation of chemotherapy infusions in academic and community-based oncology practices. Journal of the National Comprehensive Cancer Network.
  5. Kuehl M, Brixner DI, Broom AD, Avery TL, Blakley RL (1998). Cytotoxicity uptake, polyglutamate formation, and antileukemic effects of 8-deaza analogues of methotrexate and aminopterin in mice. Cancer Res, 48((6)), 1481-8.
  6. Schwarzer R, Rochau U, Saverno K, Jahn B, Bornschein B, Muehlberger N, Flatscher-Thoeni M, Schnell-Inderst P, Sroczynski G, Lackner M, Schall I, Hebborn A, Pugner K, Fehervari A, Brixner DI, Siebert U (In Press). Systematic overview of cost-effectiveness thresholds in ten countries across four continents with a special focus on personalized cancer medicine. Personalized Medicine.

Abstract

  1. Stanford J, Martin J, Gibson M, Birdsall E, Brixner DI (In Press). Use of Clomiphene Citrate in the University of Utah Community Clinics [Abstract]. The Journal of Reproductive Medicine.

Poster

  1. Udomaksorn S, Stenehjem D, Welch B, Cheng Y, Anderson L, Colonna S, Neumayer L, Brixner DI (11/2/2013). Evaluation of Variable Relevance and Accessibility to Support Personalized Medicine in Breast Cancer. Poster session presented at ISPOR 16th Annual European Congress, Dublin, Ireland.
  2. Stenehjem D, Yoo, M, Unni S, Singhal M, Bauer H, Savarno K, Quaah C, Masaquel A, Brixner DI (November 1-2, 2013). Assessment of Single-institution HER2 Testing Patterns, Rate of HER2+ Disease and Utilization of Trastuzumab in Early Breast Cancer. Poster session presented at ASCO’s Quality Care Symposium, San Diego, CA.
  3. Stenehjem D, Jiao T, Rhien T, Bellows BK, Kaldate RR, Jones J, Brixner DI (November 2, 2013). Literature Review and Assessment to Populate a Decision-analytic Model Evaluating a Novel Prognostic in Early Lung Cancer. Poster session presented at ISPOR 16th Annual European Congress, Dublin, Ireland.
  4. Welch B, Udomaksorn S, Cheng Y, Stenehjem D, Colonna S, Kawamoto K, Brixner DI (May 5-6, 2013). Desired Attributes for a Point-of-Care Breast Cancer Clinical Dashboard Supporting Personalized Health Care. Poster session presented at 2013 Cleveland Clinic Personalized Healthcare Summit, Cleveland, Ohio.
  5. Beate J, Stenehjem D, Saverno K, Cai B, Siebert W, Brixner DI (11/6/2012). Preliminary Outcomes Towards a Risk-Based Microsimulation Decision-Analytical Model Based on Treatment and Cost Inputs From a Real World Cohort of Breast Cancer Patients. Poster session presented at ISPOR 15th Annual European Congress, Berlin, Germany.
  6. Beate J, Stenehjem D, Saverno K, Cai B, Siebert W, Brixner DI (October 17-20, 2012). Preliminary Outcomes Towards a Risk-Based Microsimulation Decision-Analytical Model Based on Treatment and Cost Inputs From a Real World Cohort of Breast Cancer Patients. Poster session presented at The 34th Annual Meeting of the Society for Medical Decision Making, Phoenix AZ.
  7. Jahn B, Stenehjem D, Saverno K, Cai B, Siebert U, Brixner DI (10/17/2012). Preliminary Outcomes Towards a Risk-Based Microsimulation Decision-Analytical Model Based on Treatment Cost Inputs From a Real World Cohort of Breast Cancer Patients. Poster session presented at The 34th Annual Meeting of the Society for Medical Decision Making, Phoenix, AZ.
  8. Brixner DI (November 6, 2012). Application of Real World Data to Inform a Breast Cancer Decision-analytic Model in Austria and the U.S. – Preliminary Outcomes of Data Collection. Poster session presented at ISPOR 15th Annual European Congress, Berlin, Germany.
  9. Saokaew S, Cai B, Kuo K, Bauer H, Albright F, Brixner DI, Stenehjem D (11/6/2012). Treatment Patterns and Outcomes of Breast Cancer Patients in a Patient-centered Retrospective Research Registry. Poster session presented at ISPOR 15th Annual European Congress, Berlin, Germany.
  10. Saokaew S, Cai B, Kuo K, Bauer H, Albright F, Brixner DI, Stenehjem D (11/6/2012). Treatment Patterns and Outcomes of Breast Cancer Patients in a Patient-centered Retrospective Research Registry. Poster session presented at ISPOR 15th Annual European Congress, Berlin, Germany.
  11. Cai B, Saokaew S, Stenehjem D, Kuo K, Bauer H, Albright F, Brixner DI (11/6/2012). Treatment Pattern and Outcomes of Ovarian Cancer Patients in a Patient-Centered Retrospective Research Registry. Poster session presented at ISPOR 15th Annual European Congress, Berlin, Germany.
  12. Jahn B, Brixner DI, Saverno K, Rochau U, Stenehjem D, Albright F, Siebert U (June 10-12, 2012). Application of Real World Data to Inform A Decision -Analytic Model in Breast Cancer in Austria and the U.S. [Poster]. Poster session presented at 14th Biennial European Meeting of the Society for Medical Decision Making, Oslo, Norway.
  13. Stenehjem D, F Albright F, K Kuo K, K Raimundo K, Brixner DI (June 1-6, 2012). Evaluating Contemporary Practice in CML via a Retrospective Research Registry of Patients across a Comprehensive Cancer Center Database. Poster session presented at International Society For Pharmacoeconomics and Outcomes Research, 17th Annual International Meeting, Washington, DC.
  14. Stenehjem D, Albright F, Saverno K, Rochau U, Siebert U, Brixner DI (June 10-12, 2012). Real World Data Inform a Decision Analytic Model in Breast Cancer in Austria and the U.S. Poster session presented at Biennial European Meeting of the Society for Medical Decision Making (SMDM Europe 2012), Oslo, Norway.
  15. Brixner, DI (November 2010). Evaluation of Support Services to Colorectal Cancer Patients in Mexico. Poster session presented at ISPOR 13th Annual European Congress, Prague, Czech Republic.