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Alex Shcheglovitov

Alex Shcheglovitov, PhD

Languages spoken: English, Ukrainian, Russian

Academic Information

Departments Primary - Neurobiology , Adjunct - Psychiatry

Divisions: Adult Psychiatry

Academic Office Information

Education History

Postdoctoral Training Stanford University
Postdoctoral Training
Department of Pharmacology, University of Virginia
Postdoctoral Training
Doctoral Training Bogomoletz Institute of Physiology
National Technical University of Ukraine "Igor Sikorsky Kyiv Polytechnic Institute"
Undergraduate National Technical University of Ukraine "Igor Sikorsky Kyiv Polytechnic Institute"

Selected Publications

Journal Article

  1. Eckle VS, Shcheglovitov A, Vitko I, Dey D, Yap CC, Winckler B, Perez-Reyes E equally contributed authors (2014). "Mechanisms by which a CACNA1H mutation in epilepsy patients increases seizure susceptibility.". J Physiol, 592(Pt 4), 795-809. (Read full article)
  2. Shcheglovitov A, Shcheglovitova O, Yazawa M, Portmann T, Shu R, Sebastiano V, Krawisz A, Froehlich W, Bernstein JA, Hallmayer JF, Dolmetsch RE (2013). "SHANK3 and IGF1 restore synaptic deficits in neurons from 22q13 deletion syndrome patients.". Nature, 503(7475), 267-71. (Read full article)
  3. Krey JF, Pasca SP, Shcheglovitov A, Yazawa M, Schwemberger R, Rasmusson R, Dolmetsch RE (2013). "Timothy syndrome is associated with activity-dependent dendritic retraction in rodent and human neurons.". Nat Neurosci, 16(2), 201-9. (Read full article)
  4. Shcheglovitov A, Vitko I, Lazarenko RM, Orestes P, Todorovic SM, Perez-Reyes E corresponding authors (2012). "Molecular and biophysical basis of glutamate and trace metal modulation of voltage-gated Ca(v)2.3 calcium channels.". J Gen Physiol, 139(3), 219-34. (Read full article)
  5. Pasca SP, Portmann T, Voineagu I, Yazawa M, Shcheglovitov A, Pasca AM, Cord B, Palmer TD, Chikahisa S, Nishino S, Bernstein JA, Hallmayer J, Geschwind DH, Dolmetsch RE (2011). "Using iPSC-derived neurons to uncover cellular phenotypes associated with Timothy syndrome.". Nat Med, 17(12), 1657-62. (Read full article)
  6. Yoo AS, Sun AX, Li L, Shcheglovitov A, Portmann T, Li Y, Lee-Messer C, Dolmetsch RE, Tsien RW, Crabtree GR equally contributed authors (2011). "MicroRNA-mediated conversion of human fibroblasts to neurons.". Nature, 476(7359), 228-31. (Read full article)
  7. Nguyen HN, Byers B, Cord B, Shcheglovitov A, Byrne J, Gujar P, Kee K, Schule B, Dolmetsch RE, Langston W, Palmer TD, Pera RR (2011). "LRRK2 mutant iPSC-derived DA neurons demonstrate increased susceptibility to oxidative stress.". Cell Stem Cell, 8(3), 267-80. (Read full article)
  8. Park CY, Shcheglovitov A, Dolmetsch R (2010). "The CRAC channel activator STIM1 binds and inhibits L-type voltage-gated calcium channels.". Science, 330(6000), 101-5. (Read full article)
  9. Shcheglovitov A, Vitko I, Bidaud I, Baumgart JP, Navarro-Gonzalez MF, Grayson TH, Lory P, Hill CE, Perez-Reyes E equally contributed authors (2008). "Alternative splicing within the I-II loop controls surface expression of T-type Ca(v)3.1 calcium channels.". FEBS Lett, 582(27), 3765-70. (Read full article)
  10. Vitko I, Shcheglovitov A, Baumgart JP, Arias-Olguin II, Murbartian J, Arias JM, Perez-Reyes E (2008). "Orientation of the calcium channel beta relative to the alpha(1)2.2 subunit is critical for its regulation of channel activity.". PLoS One, 3(10), e3560. (Read full article)
  11. Shcheglovitov A, Kostyuk P, Shuba Y (2007). "Selectivity signatures of three isoforms of recombinant T-type Ca2+ channels.". Biochim Biophys Acta, 1768(6), 1406-19. (Read full article)
  12. Shcheglovitov A, Zhelay T, Vitko Y, Osipenko V, Perez-Reyes E, Kostyuk P, Shuba Y (2005). "Contrasting the effects of nifedipine on subtypes of endogenous and recombinant T-type Ca2+ channels.". Biochem Pharmacol, 69(5), 841-54. (Read full article)


  1. Shcheglovitov A, Rao M, Yoo A (2018). Special issue on stem cell and tissue engineering in development, disease, and repair. Dev Dyn, 248(1), 7-9. (Read full article)