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Alton Swennes

Alton Swennes, DVM, MS, DACLAM

Languages spoken: English

Academic Information

Departments Primary - Pathology

Academic Office Information

Education History

Postdoctoral Fellowship Massachusetts Institute of Technology
Postdoctoral Fellow
University of Georgia College of Veterinary Medicine
Graduate Training University of Georgia
University of Georgia

Selected Publications

Journal Article

  1. Aguirre AM, Yalcinkaya N, Wu Q, Swennes A, Tessier ME, Roberts P, Miyajima F, Savidge T, Sorg JA (2021). Bile acid-independent protection against Clostridioides difficile infection. PLoS Pathog, 17(10), e1010015.
  2. Schwabkey Z, Wiesnoski DH, Chang C-C, Tsai W-B, Pham D, Ahmed SS, Hayase T, Turrubiates MRO, El-Himri RK, Sanchez CA, Hayase E, Oquendo ACF, Miyama T, Halsey TM, Heckel BE, Brown AN, Jin Y, Lorenzi PL, Warmoes MO, Tan L, Swennes AG, Jensen VB, Peterson CB, Do K-A, Zhang L, Shi Y, Wang Y, Galloway-Pena JR, Okhuysen PC, Daniel-MacDougall CR, Shono Y, Burgos da Silva M, Peled JU, van den Brink MRM, Ajami N, Wargo JA, Rondon G, Srour SA, Mehta RS, Alousi AM, Shpall EJ, Champlin RE, Shelburne SA, Molldrem JJ, Jamal MA, Karmouch JL, Jenq RR (2021). Diet-derived metabolites and mucus link the gut microbiome to fever after cytotoxic cancer treatment. bioRxiv.
  3. Marini RP, Patterson MM, Muthupalani S, Feng Y, Holcombe H, Swennes AG, Ducore R, Whary MM, Shen Z, Fox JG (2021). Helicobacter suis and Helicobacter pylori infection in a colony of research macaques: characterization and clinical correlates. J Med Microbiol, 70(3).
  4. Tataryn NM, Buckmaster CA, Schwiebert RS, Swennes AG (2020). Comparison of Four Beddings for Ammonia Control in Individually Ventilated Mouse Cages. J Am Assoc Lab Anim Sci, 60(1), 37-43.
  5. Zuo X, Deguchi Y, Xu W, Liu Y, Li HS, Wei D, Tian R, Chen W, Xu M, Yang Y, Gao S, Jaoude JC, Liu F, Chrieki SP, Moussalli MJ, Gagea M, Sebastian MM, Zheng X, Tan D, Broaddus R, Wang J, Ajami NJ, Swennes AG, Watowich SS, Shureiqi I (2019). PPARD and Interferon Gamma Promote Transformation of Gastric Progenitor Cells and Tumorigenesis in Mice. Gastroenterology, 157(1), 163-178.
  6. Valentine GC, Seferovic MD, Fowler SW, Major AM, Gorchakov R, Berry R, Swennes AG, Murray KO, Suter MA, Aagaard KM (2018). Timing of gestational exposure to Zika virus is associated with postnatal growth restriction in a murine model. Am J Obstet Gynecol, 219(4), 403.e1-403.e9.
  7. Zaheer M, Wang C, Bian F, Yu Z, Hernandez H, de Souza RG, Simmons KT, Schady D, Swennes AG, Pflugfelder SC, Britton RA, de Paiva CS (2018). Protective role of commensal bacteria in Sjögren Syndrome. J Autoimmun, 93, 45-56.
  8. Wang C, Zaheer M, Bian F, Quach D, Swennes AG, Britton RA, Pflugfelder SC, de Paiva CS (2018). Sjögren-Like Lacrimal Keratoconjunctivitis in Germ-Free Mice. Int J Mol Sci, 19(2).
  9. Gopalakrishnan V, Spencer CN, Nezi L, Reuben A, Andrews MC, Karpinets TV, Prieto PA, Vicente D, Hoffman K, Wei SC, Cogdill AP, Zhao L, Hudgens CW, Hutchinson DS, Manzo T, Petaccia de Macedo M, Cotechini T, Kumar T, Chen WS, Reddy SM, Szczepaniak Sloane R, Galloway-Pena J, Jiang H, Chen PL, Shpall EJ, Rezvani K, Alousi AM, Chemaly RF, Shelburne S, Vence LM, Okhuysen PC, Jensen VB, Swennes AG, McAllister F, Marcelo Riquelme Sanchez E, Zhang Y, Le Chatelier E, Zitvogel L, Pons N, Austin-Breneman JL, Haydu LE, Burton EM, Gardner JM, Sirmans E, Hu J, Lazar AJ, Tsujikawa T, Diab A, Tawbi H, Glitza IC, Hwu WJ, Patel SP, Woodman SE, Amaria RN, Davies MA, Gershenwald JE, Hwu P, Lee JE, Zhang J, Coussens LM, Cooper ZA, Futreal PA, Daniel CR, Ajami NJ, Petrosino JF, Tetzlaff MT, Sharma P, Allison JP, Jenq RR, Wargo JA (2017). Gut microbiome modulates response to anti-PD-1 immunotherapy in melanoma patients. Science, 359(6371), 97-103.
  10. Hibl BM, Fowler SW, Southern CT, Swennes AG, Buckmaster CA (2018). Cellulose-based bedding as an alternative to corn cob for rodent colonies. Animal Lab News, 16(5), 14-17.
  11. Feng Y, Mannion A, Madden CM, Swennes AG, Townes C, Byrd C, Marini RP, Fox JG (2017). Cytotoxic Escherichia coli strains encoding colibactin and cytotoxic necrotizing factor (CNF) colonize laboratory macaques. Gut Pathog, 9, 71.
  12. Swennes AG, Parry NMA, Feng Y, Sawyer E, Lohr BR, Twedt DC, Fox JG (2016). Enterohepatic Helicobacter spp. in cats with non-haematopoietic intestinal carcinoma: a survey of 55 cases. J Med Microbiol, 65(8), 814-820.
  13. Esmail MY, Bacon R, Swennes AG, Feng Y, Shen Z, Garcia A, Sharma P, Cohen J, Fox JG (2015). Helicobacter Species Identified in Captive Sooty Mangabeys (Cercocebus atys) with Metastatic Gastric Adenocarcinoma. Helicobacter, 21(3), 175-85.
  14. Gill J, Haydon TG, Rawdon TG, McFadden AM, Ha HJ, Shen Z, Feng Y, Pang J, Swennes AG, Paster BJ, Dewhirst FE, Fox JG, Spence RP (2016). Helicobacter bilis and Helicobacter trogontum: infectious causes of abortion in sheep. J Vet Diagn Invest, 28(3), 225-34.
  15. Yu DH, Gadkari M, Zhou Q, Yu S, Gao N, Guan Y, Schady D, Roshan TN, Chen MH, Laritsky E, Ge Z, Wang H, Chen R, Westwater C, Bry L, Waterland RA, Moriarty C, Hwang C, Swennes AG, Moore SR, Shen L (2015). Postnatal epigenetic regulation of intestinal stem cells requires DNA methylation and is guided by the microbiome. Genome Biol, 16, 211.
  16. Swennes AG, Sheh A, Parry NM, Muthupalani S, Lertpiriyapong K, Garca A, Fox JG (2014). Helicobacter hepaticus infection promotes hepatitis and preneoplastic foci in farnesoid X receptor (FXR) deficient mice. PLoS One, 9(9), e106764.
  17. Swennes AG, Turk ML, Trowel EM, Cullin C, Shen Z, Pang J, Petersson KH, Dewhirst FE, Fox JG (2013). Helicobacter canis colonization in sheep: a Zoonotic link. Helicobacter, 19(1), 65-8.
  18. Swennes AG, Buckley EM, Madden CM, Byrd CP, Donocoff RS, Rodriguez L, Parry NM, Fox JG (2013). Enteropathogenic Escherichia coli prevalence in laboratory rabbits. Vet Microbiol, 163(3-4), 395-8.
  19. Swennes AG, Buckley EM, Parry NM, Madden CM, Garca A, Morgan PB, Astrofsky KM, Fox JG (2012). Enzootic enteropathogenic Escherichia coli infection in laboratory rabbits. J Clin Microbiol, 50(7), 2353-8.
  20. Shringi S, Garca A, Lahmers KK, Potter KA, Muthupalani S, Swennes AG, Hovde CJ, Call DR, Fox JG, Besser TE (2011). Differential virulence of clinical and bovine-biased enterohemorrhagic Escherichia coli O157:H7 genotypes in piglet and Dutch belted rabbit models. Infect Immun, 80(1), 369-80.
  21. Swennes AG, Alworth LC, Harvey SB, Jones CA, King CS, Crowell-Davis SL (2011). Human handling promotes compliant behavior in adult laboratory rabbits. J Am Assoc Lab Anim Sci, 50(1), 41-5.
  22. Pattathil S, Avci U, Baldwin D, Swennes AG, McGill JA, Popper Z, Bootten T, Albert A, Davis RH, Chennareddy C, Dong R, OShea B, Rossi R, Leoff C, Freshour G, Narra R, ONeil M, York WS, Hahn MG (2010). A comprehensive toolkit of plant cell wall glycan-directed monoclonal antibodies. Plant Physiol, 153(2), 514-25.
  23. Swennes AG, Findly RC, Dickerson HW (2006). Cross-immunity and antibody responses to different immobilisation serotypes of Ichthyophthirius multifiliis. Fish Shellfish Immunol, 22(6), 589-97.
  24. Swennes AG, Noe JG, Findly RC, Dickerson HW (2006). Differences in virulence between two serotypes of Ichthyophthirius multifiliis. Dis Aquat Organ, 69(2-3), 227-32.

Book Chapter

  1. Carter PB, Noren EL, Swennes AG (2019). Gnotobiotics and the Microbiome. In Suckow M, Hankenson FC, Wilson R, Foley P (Eds.), The Laboratory Rat (American College of Laboratory Animal Medicine Series) (3rd Edition). Cambridge, MA: Academic Press.
  2. Boyd C, Eaton KA, Schoeb TR, Swennes AG, Bickerton H, Parsons BJ, Sinclair S, Vowles C (2017). Procedures for Rodents. In Schoeb TR, Eaton KA (Eds.), Gnotobiotics (American College of Laboratory Animal Medicine Series) (1st Edition). Cambridge, MA: Academic Press.
  3. Swennes AG, Fox JG (2014). Ferret Bacterial Diseases. In Fox JG, Marini RP (Eds.), Biology and Diseases of the Ferret (3rd Edition). Hoboken, NJ: Wiley-Blackwell.

Case Report

  1. Frydman GH, Metcalf Pate KA, Marini RP, de Laforcade AM, Bosch I, Bakthavatchalu V, Muthupalani S, Swennes AG, Lyons CE, Tompkins RG, Fox JG (2017). Adult-onset, chronic, cyclic thrombocytopenia in a Rhesus macaque (Macaca mulatta) after dengue virus vaccination and viral challenge. Vet Clin Pathol, 46(2), 238-247.